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Schrodinger

HQ: New York, NY source · schrodinger.com ↗ · New England

Clinical Phase 1

Location: New York, NY · source · Oct 13, 2026

Profile checked Oct 10, 2026

Keywords: Mature B-Cell Neoplasm Non Hodgkin Lymphoma DLBCL Waldenstrom Macroglobulinemia MALT Lymphoma Follicular Lymphoma Pediatric-Type Follicular Lymphoma IRF4 Gene Rearrangement Nos EBV-Positive DLBCL Burkitt Lymphoma Plasmablastic Lymphoma High-grade B-cell Lymphoma Primary Cutaneous Follicle Center Lymphoma Primary Effusion Lymphoma Mantle Cell Lymphoma DLBCL Germinal Center B-Cell Type Primary Mediastinal Large B Cell Lymphoma T-Cell/Histiocyte Rich Lymphoma ALK-Positive Large B-Cell Lymphoma Primary Cutaneous Diffuse Large B-Cell Lymphoma Splenic Marginal Zone Lymphoma Chronic Lymphocytic Leukemia Nodal Marginal Zone Lymphoma Nos HHV8-Positive DLBCL Lymphoplasmacytic Lymphoma Duodenal-Type Follicular Lymphoma Acute Myeloid Leukemia High-Risk and Very High-Risk Myelodysplastic Syndromes SGR-1505 SGR-2921 SGR-3515

3Trials (company is sponsor)15NIH grants

Timeline

  1. Trial start Phase 1: Study of SGR-3515 In Participants With Advanced Solid Tumors. source ↗
  2. Trial start Phase 1: Study of SGR-2921 in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome source ↗
  3. Trial start Phase 1: Study of SGR-1505 in Mature B-Cell Neoplasms source ↗

Upcoming milestones

Estimated primary completion per ClinicalTrials.gov. Dates move.

Clinical trials (lead sponsor) 3

RecordTitlePhaseStatusStartPrimary completion
NCT05544019Study of SGR-1505 in Mature B-Cell NeoplasmsPhase 1RecruitingApr 10, 20232027-11 (estimated)
NCT05961839Study of SGR-2921 in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic SyndromePhase 1TerminatedSep 27, 2023Aug 14, 2025 (actual)
NCT06463340Study of SGR-3515 In Participants With Advanced Solid Tumors.Phase 1RecruitingJun 18, 2024Oct 31, 2026 (estimated)

NIH awards 15

Annual award amounts. Total $3.7M.

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