Upcoming trial dates

3,252 active trials (company is sponsor) with an estimated primary completion from Oct 2026 on. Estimated per ClinicalTrials.gov; dates move.

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Oct 2026 (estimated) · 97 trials

Phase 2 · Acumen Pharmaceuticals · A Study to Evaluate Efficacy and Safety of Intravenous Sabirnetug in Participants With Early Alzheimer's Disease (ALTITUDE-AD) NCT06335173
Not applicable · Alpha Tau Medical · Alpha Radiation Emitters (DaRT) With Chemotherapy for the Treatment of Locally Advanced and Metastatic Pancreatic Cancer NCT06698458
Not applicable · Alpha Tau Medical · Alpha Radiation Emitters Device for the Treatment of Advanced Pancreatic Cancer NCT04002479
Phase 1 · BioCryst Pharmaceuticals · A Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of BCX17725 NCT06539507
Phase 2/Phase 3 · Biohaven · Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy NCT06309966
Early phase 1 · Cajal Therapeutics · A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CTX001 in Healthy Adults. NCT07577817
Phase 1 · Calico · Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors NCT04777994
Not applicable · CardioFocus · CardioFocus HeartLight Post-Approval Study NCT03168659
Phase 3 · Celldex Therapeutics · A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria NCT06445023
Phase 3 · Celldex Therapeutics · A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU) NCT06455202
Not applicable · Ceribell · Ceribell Delirium Monitor Outcomes Pilot Study NCT07449416
Not applicable · Conceivable Life Sciences · Automation of the In Vitro Fertilization Laboratory NCT06581068
Phase 2 · Corcept Therapeutics · Dazucorilant in Patients With Amyotrophic Lateral Sclerosis NCT05407324
Phase 1 · Corsera Health · A Study to Evaluate COR-1004 in Adult Volunteers. NCT07229118
Phase 1/Phase 2 · Crinetics Pharmaceuticals, Inc. · A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome NCT05804669
Phase 1 · Deciphera Pharmaceuticals, LLC · Evaluate the Effect of Vimseltinib on Pharmacokinetics of Combined Oral Contraceptive (Ethinyl Estradiol/Levonorgestrel) NCT07539090
Phase 2 · Disc Medicine · Study of DISC-0974-201 in Participants With IBD and Anemia NCT07368972
Phase not stated · Eko Devices · Detection of Reduced Left Ventricular Ejection Fraction With Three-Lead ECG Using Artificial Intelligence NCT07270692
Phase 1 · Eli Lilly · A Study of LY4268989 (MORF 057) in Healthy Participants NCT07707375
Phase 1 · Endeavor BioMedicines · A Study to Evaluate Pharmacokinetics and Drug-drug Interactions of ENV-101 (Taladegib) in Healthy Participants NCT07454291
Phase 2 · Endeavor BioMedicines · A Phase 2 Trial of ENV-101 in Patients With Lung Fibrosis (WHISTLE-PF Trial) NCT06422884
Phase 2 · GEn1E Lifesciences · A Study of GEn-1124 in Subjects With Acute Respiratory Distress Syndrome (ARDS) NCT05795465
Not applicable · GI Windows · Initial Safety of SFM Plus OTOLoc for Creating Side-to-side or End-to-side Colorectal Anastomoses NCT07276529
Phase 1 · Gilead · Study of GS-4528 in Adults With Solid Tumors NCT05840224
Phase 1 · IDEAYA Biosciences · A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors NCT05787587
Phase 2 · ImmunityBio · A Study to Assess Anktiva in Patients With Long Covid-19. NCT07108036
Phase 2 · Immunovant · A Study to Assess the Safety, Tolerability, and Efficacy of IMVT-1402 in Participants With Cutaneous Lupus Erythematosus (CLE) NCT06980805
Early phase 1 · Janux Therapeutics · Study of JANX011 in Healthy Adult Volunteers to Assess Safety and Tolerability. NCT07291323
Phase 3 · Mirum Pharmaceuticals · Evaluation of Maralixibat in Pruritus Associated With General Cholestatic Liver Disease (EXPAND) NCT06553768
Phase not stated · Neuspera Medical · FREEDOM Registry - Follow up Revision Experience and Evaluation of Device Outcomes Metrics NCT07383688
Phase 2 · Novaliq · Tacrolimus Ophthalmic Solution for the Treatment of Non-infectious Anterior Uveitis NCT07285070
Not applicable · PathMaker Neurosystems · Controlling Amyotrophic Lateral Sclerosis Motor Neuron Excitability Study NCT06649955
Phase 1 · PEEL Therapeutics · A Study to Evaluate PEEL-224 in Patients With Advanced Solid Tumors NCT05329103
Phase 2 · Phathom Pharmaceuticals · A Study in Adult Participants With EoE to Evaluate Vonoprazan 20 mg Compared to Placebo After 12 Weeks and to Evaluate Vonoprazan 20 mg Up to 24 Weeks NCT06851559
Phase 2/Phase 3 · Privo Technologies · A Study Evaluating the Safety and Efficacy of PRV111, PRV211, and PRV131 in Subjects With Oral and Lung Cancers NCT05893888
Not applicable · Pulse Biosciences, Inc. · NS-PFA Catheter Ablation of Paroxysmal Atrial Fibrillation With the Pulse Biosciences CellFX System NCT07018596
Phase 2 · Qlaris Bio · Single-site Pilot Study Evaluating the Effect of QLS-111 Ophthalmic Solution on Posterior Perfusion and Vessel Dilation NCT07354477
Phase 1 · Sorrento Therapeutics, Inc. · Study to Assess the Safety and Preliminary Efficacy of STI-1386 Oncolytic Virus in Relapsed or Refractory Solid Tumors NCT05361954
Phase 1 · SOTIO Biotech · A Study to Assess Safety and Efficacy of SOT201 in Patients With Advanced/Metastatic Cancer NCT06163391
Phase not stated · TransMedics · OCS DCD Heart + CAP Continued Follow-Up NCT05741723
Phase 2 · Triveni Bio · A Study Evaluating TRIV-509 in Atopic Dermatitis NCT07167758
Phase 2 · Vanda Pharmaceuticals · Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension NCT07090161
Phase 4 · Viatris (2) · Dymista in Chinese Adolescents NCT07597473
Phase not stated · Vima Therapeutics · An Observational Study of Individuals With Isolated Dystonia NCT07111663
Phase 1/Phase 2 · Cocrystal Pharma Inc. · A Study to Evaluate the Efficacy, Safety and Pharmacokinetics of CDI-988 in Healthy Adults After Challenge With Snow Mountain Virus NCT07198139
Phase not stated · Natera · The PROspera Kidney Transplant ACTIVE Rejection Assessment Registry (ProActive) NCT04091984
Phase 3 · Novo Nordisk A/S · A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation NCT06200207
Phase 2 · Taiho Oncology · Phase 2 Futibatinib in Combination With PD-1 Antibody Based Standard of Care in Solid Tumors NCT05945823
Phase 1 · Viking Therapeutics · A Phase 1 Study of VK3019 in Overweight and Obese Adults Without Comorbidities NCT07846033
Phase 1/Phase 2 · Moderna · A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189, in 10- to 30-Year-Old Healthy Adolescents and Adults NCT05164094
Phase 3 · Swedish Orphan Biovitrum · A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis NCT03165734
Phase 1 · Bayer AG · A Study to Learn About How a New Nurandociguat Tablet is Absorbed and Processed in the Body Compared to an Old Tablet and How Food Affects the Way the New Tablet is Absorbed and Processed in the Body NCT07722585
Phase 1 · Elixirgen Therapeutics · Study to Evaluate of EXG34217 in Patients With Telomere Biology Disorders With Bone Marrow Failure NCT04211714
Phase 3 · Incyte · Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS1) NCT06959225
Phase 3 · Incyte · Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS2) NCT06958211
Phase 1/Phase 2 · Aspa Therapeutics · A Study of AAV9 Gene Therapy in Participants With Canavan Disease (CANaspire Clinical Trial) NCT04998396
Phase 1 · Moderna · A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1195, in 18- to 55-Year-Old Healthy Participants NCT05831111
Phase 1 · Boehringer Ingelheim · A Study to Test How BI 3034701 is Taken up and Processed by the Body in Healthy Men With Normal Weight or Overweight NCT07708493
Phase not stated · CareDx · Assessment of Chimerism and Relapse Post Bone Marrow/Hematopoietic Cell Transplant (HCT) Using AlloHeme Test NCT04635384
Phase 1 · Incyte · A Study to Assess the Mass Balance, Pharmacokinetics, and Metabolite Profiles of a Single Oral Dose of [14C]-INCB161734 in Healthy Male Participants NCT07814404
Phase not stated · Magnus Medical · Open Label Optimization Study NCT05819021
Phase 1/Phase 2 · Solid Biosciences Inc. · Microdystrophin Gene Transfer Study in Adolescents and Children With DMD NCT03368742
Phase 1 · Osel · CBM588 Capsules in Combination With Nivolumab and Ipilimumab for the Treatment of Advanced Stage Kidney Cancer NCT06399419
Phase 2/Phase 3 · Biogen · A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus NCT05531565
Phase 1/Phase 2 · Daiichi Sankyo · First-in-Human Study of DS-3939a in Participants With Advanced Solid Tumors NCT05875168
Phase not stated · Septodont · Tooth Retention After Root Canal Treatment With Endomethasone N NCT04945993
Phase 3 · Novartis · Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-ob NCT05360446
Phase 1 · Vertex Pharmaceuticals Incorporated · A Phase 1 Relative Bioavailability Study of a VX-581 Tablet Formulation NCT07813039
Phase 1 · Alzheon · Safety and Pharmacokinetics of ALZ-507 in Healthy Elderly Adults NCT07824271
Phase not stated · Bayer AG · An Observational Study to Learn How Mirena and Other Progestogen Treatments Are Used for Endometrial Protection in Women 40+ With a Uterus in the United States Receiving Estrogen Therapy, and Their Re NCT07795606
Phase 1 · Cayuga Biotech · Study to Evaluate CAY001 in Healthy Volunteers NCT06845839
Not applicable · ConvaTec · ConvaVAC™ Ag+ Negative Pressure Wound Therapy System in Chronic Wounds NCT07342049
Phase 1 · Corcept Therapeutics · Evaluating the Pharmacokinetics and Safety of Miricorilant NCT07553663
Phase 1 · INIMMUNE CORPoration · Trial of INI-4001 in Patients With Advanced Solid Tumours NCT06302426
Phase 1 · MBX Biosciences · A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MBX 4291 in Adult Participants With Obesity NCT07142707
Phase not stated · PinkDx · Investigations of Reproductive Cancers in Women NCT06527157
Phase 3 · Vertex Pharmaceuticals Incorporated · A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy NCT05444257
Not applicable · Ancora Heart · Evaluate the Safety and Performance of the AccuCinch® Ventricular Repair System - The CorCinch-EU Study NCT03183895
Not applicable · Arsenal Medical, Inc. · REVIVE: Reducing Exsanguination Via In-Vivo Expandable Foam NCT02880163
Phase 2 · AskBio · Phosphatase Inhibition by Intracoronary Gene Therapy in Subjects With Non-Ischemic NYHA Class III Heart Failure NCT05598333
Phase not stated · Biogen · A Study Utilising Data From European Union (EU) National Multiple Sclerosis (MS) Registries to Assess the Incidence of Anti-Natalizumab Antibody Among Participants Who Receive Subcutaneous Administrat NCT05925049
Phase not stated · Bristol-Myers Squibb · Asia Myelodysplastic Syndrome (MDS) Registry NCT07355478
Phase not stated · CathVision · Repeatable Evaluation of Functional Intra-procedural Signals for Effect in Pulsed Field Ablation REFINE-PFA NCT07275151
Not applicable · Cochlear · New Algorithms to Signal Processing for Speech Enhancement in Adult Cochlear Implant Recipients. NCT06100393
Not applicable · Hyperfine · Evaluation of Gadolinium Based Contrast Agents for Portable MR Imaging Systems NCT07296263
Phase 1 · Myosin Therapeutics Inc. · A Phase 1/2 Study of the Safety and Tolerability of MT-125 in GBM Patients NCT07185880
Phase not stated · Natera · Prospera Test Evaluation in Cardiac Transplant (ProTECT) NCT05205551
Phase 3 · Olema Oncology · OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer NCT06016738
Phase 1 · Replimune · Study of RP2 Monotherapy and RP2 in Combination With Nivolumab in Patients With Solid Tumors NCT04336241
Phase 2 · Rhythm Pharmaceuticals · A Study of Setmelanotide in Patients With Prader-Willi Syndrome NCT06772597
Phase 2 · Salubris Biotherapeutics · Study of JK07 in Patients With Chronic Heart Failure NCT06369298
Phase 3 · Sarepta Therapeutics, Inc. · A Study to Compare Safety and Efficacy of High Doses of Eteplirsen in Participants With Duchenne Muscular Dystrophy (DMD) (MIS51ON) NCT03992430
Phase 1 · Schrodinger · Study of SGR-3515 In Participants With Advanced Solid Tumors. NCT06463340
Phase 1 · SpringWorks Therapeutics · Effect of Hepatic Impairment on the Pharmacokinetics of Mirdametinib NCT06997276
Phase 2 · Spyre Therapeutics · A Study of SPY072 in Rheumatic Disease NCT07148414
Phase not stated · Tasso, Inc · Clinical Performance of Capillary Blood Samples Collected Using the Tasso+ Serum Gel Capillary Blood Collection System for Clinical Chemistry Testing of 14 Analytes on an Abbott Alinity Analyzer NCT07260799
Phase 1/Phase 2 · Xentria · Study of Multiple-Ascending-Dose Study of XTMAB-16 in Patients With Pulmonary Sarcoidosis With or Without Extrapulmonary Manifestations NCT05890729

Nov 2026 (estimated) · 95 trials

Phase 2 · Alkermes, Inc. · A Study to Evaluate the Safety and Effectiveness of ALKS 2680 in Subjects With Idiopathic Hypersomnia NCT06843590
Not applicable · Alpha Tau Medical · Alpha Radiation Emitters Device for the Treatment of Advanced Pancreatic Cancer (Feasibility and Safety) NCT05657743
Not applicable · AngioDynamics · Percutaneous AngioVac Vegetation Extraction (PAVE) to Remove Right Heart Vegetations in Patients With Infective Endocarditis NCT07282002
Phase 2 · Apogee Therapeutics · A Study Evaluating APG777 in Atopic Dermatitis NCT06395948
Phase 1/Phase 2 · Aptose Biosciences · Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia NCT03850574
Early phase 1 · Barinthus Biotherapeutics · VTP-1000 in Adults With Celiac Disease NCT06310291
Phase 1 · Bausch + Lomb · A Study to Assess Safety, Tolerability, and Pharmacokinetics of Ascending Concentrations of Topical Ocular BL1332 in Healthy Volunteers NCT06978244
Not applicable · Bausch + Lomb · Effectiveness and Safety of the TENEO 317 Model 2 Excimer Laser to Treat Myopia With or Without Astigmatism by Transepithelial Photorefractive Keratectomy NCT06618547
Phase not stated · Becton Dickinson · HemoSphere Alta Study NCT07148323
Phase not stated · Becton Dickinson · UK PureWick™ At-Home Pilot Study NCT07555548
Phase 1/Phase 2 · Bexion Pharmaceuticals · BXQ-350 in Newly Diagnosed Metastatic Colorectal Carcinoma NCT05322590
Phase 1 · Biohaven · A Phase 1b Study of BHV-7000 in Participants With Inherited Erythromelalgia NCT07262268
Phase 2 · BioNTech US Inc. · A Phase II Clinical Trial Comparing the Efficacy of RO7198457 Versus Watchful Waiting in Patients With ctDNA-positive, Resected Stage II (High Risk) and Stage III Colorectal Cancer NCT04486378
Phase 1 · BioNTech US Inc. · A Clinical Trial Investigating the Safety and Biological Activity of the Antibody BNT351 in Adults Living Without and With HIV NCT07392372
Phase not stated · CareDx · Surveillance HeartCare® Outcomes Registry NCT03695601
Phase 3 · CG Oncology · A Study of Adjuvant Cretostimogene Grenadenorepvec for Treatment of Intermediate Risk NMIBC Following TURBT NCT06111235
Phase 1 · Cullinan Therapeutics Inc. · A Study of CLN-978 in Patients With Relapsed or Refractory (R/R) B Cell Non-Hodgkin Lymphoma (B-NHL) NCT05879744
Phase 1 · Enanta Pharmaceuticals · A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of EDP-978 in Healthy Adults NCT07540910
Phase 1 · GRIN Therapeutics · Honeycomb: Evaluation of Radiprodil in Children with GRIN-related Disorder NCT05818943
Not applicable · GT Metabolic Solutions · GT Metabolic Magnet System in Adults With Gastrointestinal Disorders NCT07317076
Phase not stated · Harbinger Health · Prospective Study to Assess a Diagnostic Aid for Cancer NCT07046260
Phase 1 · HiberCell · A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma NCT06234605
Phase 2 · IGC Pharma · Clinical Trial on Agitation in Alzheimer's Dementia NCT05543681
Phase 2 · ImmunityBio · Clinical Trial of Ablation Therapy in Participants With Intermediate-Risk Non-Muscle Invasive Papillary Bladder Cancer NCT06829823
Phase 2 · Kiora Pharmaceuticals · Safety, Tolerability and Efficacy of Intravitreal KIO-104 in Patients With Macular Edema NCT06825702
Early phase 1 · Krystal Biotech · A Study to Investigate Safety and Efficacy of KB111 for the Treatment of Hailey-Hailey Disease NCT07717346
Phase 1 · MacroGenics · A Study of MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies NCT05362773
Phase 1 · MacroGenics · A Study of MGC028 in Participants With Advanced Solid Tumors NCT06723236
Phase 3 · Medicure · Oral Pyridoxal 5'-Phosphate for the Treatment of Patients With PNPO Deficiency NCT04706013
Not applicable · NeuralInk · UAE-PRIME: A Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices NCT06992596
Not applicable · Neuspera Medical · Study of 30-Minute Stimulation With the Neuspera Sacral Neuromodulation (SNM) System NCT07247136
Phase 2 · ReCode Therapeutics · A Phase 2 Study Evaluating Safety and Tolerability of RCT2100 (CFTR mRNA) in Healthy Participants and in Participants With CF NCT06237335
Phase 2 · Reunion Neuroscience · RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses NCT07002034
Phase 2 · SciNeuro Pharmaceuticals · A Phase 2a Study to Evaluate the Safety, Tolerability, and Efficacy of SNP318 in DME Patients NCT07199777
Phase 3 · SK Life Science · Safety and Efficacy Study of Cenobamate in Pediatric Subjects 2-17 Years of Age With Partial-onset (Focal) Seizures NCT05067634
Phase 1 · Sonoma Biotherapeutics · Study of Single Doses of SBT777101 in Subjects With Rheumatoid Arthritis NCT06201416
Phase 1 · Sonoma Biotherapeutics · Study of Single Doses of SBT777101 in Subjects With Hidradenitis Suppurativa NCT06361836
Phase 2 · Stemline Therapeutics · ELACESTRANT in Women and Men With CDK4/6 Inhibitor-Naive Estrogen Receptor Positive, HER-2 Negative Metastatic Breast Cancer Study NCT05596409
Phase 1/Phase 2 · Tyra Biosciences · Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations NCT05544552
Phase 2 · Vir Biotechnology · A Study to Evaluate Tobevibart+Elebsiran Versus Bulevirtide in Chronic HDV Infection NCT07142811
Not applicable · Vivalyx · Hypothermic Machine Perfusion With Omnisol of Deceased Donor Kidneys Prior to Transplantation NCT07792317
Phase 2 · Xentria · An Open-label Extension Study of XTMAB-16 in Patients With Pulmonary Sarcoidosis NCT06169397
Phase not stated · Zimmer Biomet · Embody Post-Market Clinical Follow-Up Study NCT05735119
Phase 2 · Zura Bio · Tibulizumab Skin Healing and Inflammation Evaluation for Lasting Defense NCT06993610
Not applicable · Alpha Tau Medical · Alpha Radiation Emitters Device (DaRT) for the Treatment of Recurrent Glioblastoma NCT06910306
Phase 1 · Consano Bio, Inc. · Study to Evaluate Safety of C-1101 Versus Sterile Saline in Adults With Chronic Painful Lumbosacral Radiculopathy NCT07264270
Phase 1/Phase 2 · Corbus Pharmaceuticals · First-in-human Study of CRB-601-01 to Treat Patients With Advanced Solid Tumor. NCT06603844
Not applicable · Edwards Lifesciences · ALT-FLOW II Trial of the Edwards APTURE Transcatheter Shunt System NCT05686317
Not applicable · Motif Neurotech · Regulated Stimulation for Optimized Network Activity and Therapeutic Equilibrium - Maintenance NCT07684794
Phase 3 · Scholar Rock, Inc. · Long-Term Safety & Efficacy of Apitegromab in Patients With SMA Who Completed Previous Trials of Apitegromab NCT05626855
Not applicable · URO-1 · Comparing Standard of Care Biopsy System to a Novel Biopsy Needle System by Computational Pathologic Analysis NCT06830265
Phase 1 · Bristol-Myers Squibb · A Phase 1 Study of Navlimetostat Tablet Formulations NCT07544628
Phase 3 · Bristol-Myers Squibb · A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2) NCT06951711
Phase 4 · Dexcom · Continuous Glucose Monitoring By DExcom iN PEople Followed for Type 2 DIabeTes on Insulin Therapy in the Kingdom of Saudi Arabia NCT07603284
Phase not stated · Novo Nordisk A/S · A Retrospective Real-World Cohort Study NCT07781371
Phase 3 · Novartis · 24 Weeks Double-blind Randomized Placebo-controlled Trial to Evaluate Efficacy, PK, Safety of LOU064 in Adolescents (12 - <18) With CSU and Inadequate Response to H1-antihistamine Followed by Optional NCT05677451
Phase 1 · Sanofi · An Open-label DDI Study to Investigate the Effect of Rilzabrutinib on P-gp, BCRP, OATP1B1 and OATP1B3 Inhibition NCT07855250
Not applicable · Hologic · Prospective Case Collection Study for New Mammography Technologies NCT05199701
Not applicable · Hologic · Prospective Case Collection Study of Contrast-Enhanced Mammography Imaging Acquired on a New Investigational Device NCT06636539
Phase not stated · Sanofi · Agalsidase Beta Long-Term Treatment Outcome for Fabry Disease Patients With IVS4 Mutation in Taiwan NCT06052800
Phase 2 · Precigen · PRGN-2009 in Combination With Pembrolizumab in Patients With Recurrent or Metastatic Cervical Cancer NCT06157151
Phase 1 · Mirador Therapeutics · A Single-Dose Study of MT-201 and Concomitant Infliximab in Healthy Participants NCT07776782
Phase 1 · LifeMine Therapeutics · A Phase I Study to Evaluate LIFE-001 NCT06904807
Phase 1 · Treeline Biosciences, Inc. · A Study of TLN-254 in Participants With Relapsed or Refractory T-cell Lymphoma NCT06733441
Phase 4 · Swedish Orphan Biovitrum · A Study to Investigate the Course of Synovial Hypertrophy in Patients With Haemophilia A on Efanesoctocog Alfa Prophylaxis NCT06752850
Phase 4 · Novavax · Efficacy and Safety of NVX-CoV2705 NCT07086222
Phase 1 · PeproMene Bio · BAFFR Targeting CAR-T Cells for the Treatment of Relapsed or Refractory B-cell ALL NCT04690595
Phase 1 · Spyre Therapeutics · A Study of SPY003-207 in Healthy Volunteers NCT06873724
Not applicable · Tides Medical · Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers NCT06681428
Phase 1 · Vertex Pharmaceuticals Incorporated · Dose Escalation Study Evaluating the Safety and Pharmacokinetics of VX-581 in Healthy Participants NCT07283770
Phase 2 · Skye Bioscience · Study to Evaluate the Effect on Obesity of QW Nimacimab and QW Nimacimab Co-administered With Semaglutide vs Placebo NCT06577090
Phase 2 · ResVerlogiX · A Two-Part Phase 2a Study of RVX000222 in Patients With End-Stage Renal Disease Treated With Hemodialysis NCT03160430
Phase 1 · Exelixis · Study of XB010 in Subjects With Solid Tumors NCT06545331
Phase 1 · Mirador Therapeutics · A First-in-Human Single and Multiple Ascending Dose Study of MT-201 NCT07219368
Phase 2 · Tectonic Therapeutic · A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study) NCT06616974
Phase 1 · Insmed · A Study to Assess the Potential CYP3A Induction Effect of Brensocatib on the Pharmacokinetics (PK) of Midazolam in Healthy Participants NCT07859007
Phase 4 · Sanofi · Study of a Recombinant Spike COVID-19 Vaccine With Matrix-M in Older Adults and People at Increased Risk of Severe COVID-19 NCT07861542
Not applicable · Levita Magnetics · Safety and Feasibility of the MACS in Surgical Procedures: A Prospective Multi-Center Study NCT07470411
Phase 2 · TrueBinding · A Phase 2a Multicenter Clinical Trial of TB006 in Participants With Parkinson's Disease NCT06773962
Phase 1 · Boehringer Ingelheim · A Study to Test Different Doses of BI 1823911 Alone and Combined With Other Medicines in People With Different Types of Advanced Cancer With KRAS Mutation NCT04973163
Phase 1/Phase 2 · Arvinas, Inc · A Study to Evaluate ARV-806 in Adults With Advanced Cancer That Has the KRAS G12D Mutation NCT07023731
Phase 2 · Aura Biosciences · Suprachoroidal Administration in Subjects With Metastases to the Choroid NCT06643884
Phase 1 · CAGE Bio · A Proof of Concept, Phase 1 Study of CGB-600 for the Topical Treatment of Non-Segmented Facial Vitiligo NCT07357870
Not applicable · GI Windows · Megagon Magnet Anastomosis Plus OTOLoc for Creating Colo-colonic and Colorectal Anastomoses NCT07856342
Phase not stated · Ipsen · Odevixibat Outcomes in Patients With PFIC Versus an External Control Cohort (OvEC-PFIC) NCT07497724
Phase 1/Phase 2 · Moderna · A Study of mRNA-3745 in Adult and Pediatric Participants With Glycogen Storage Disease Type 1a (GSD1a) NCT05095727
Phase 1/Phase 2 · NeOnc Technologies · Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma NCT02704858
Not applicable · Neptune Medical · Triton 1.5 Robotic System for Diagnostic Colonoscopy in the Middle East NCT07835542
Phase 1/Phase 2 · OncoC4 · ONC-392 Plus Lutetium Lu 177 Vipivotide Tetraxetan in Patients With mCRPC NCT05682443
Phase 1 · Replimune · Study of RP3 Monotherapy and RP3 in Combination With Nivolumab in Patients With Solid Tumours NCT04735978
Not applicable · Rhaeos, Inc. · Study of Shunt Flow Under Different Valve Settings Using a Wireless Sensor NCT07679035
Phase 1 · Rise Therapeutics · R-2487 in Patients With Rheumatoid Arthritis NCT05961592
Phase 3 · Saol Therapeutics · Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain NCT07226258
Phase 2 · Takeda · A Study of TAK-360 in Adults With Narcolepsy Without Cataplexy (NT2) NCT06952699
Phase not stated · Vertero Therapeutics · Research Into the Expression of the csgA-gene and How it Changes in Patients With Parkinson's Disease NCT07175922

Dec 2026 (estimated) · 293 trials

Phase 1/Phase 2 · 858 Therapeutics · A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies NCT06395519
Phase 1/Phase 2 · A2 Biotherapeutics · A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression NCT05736731
Phase 1 · Actio Biosciences · A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ABS-1230 Given Orally Compared With Placebo in Healthy Participants Aged 18 to 55 Years NCT07156201
Phase not stated · Advanced Bionics · Evaluation of Remote Programming of Cochlear Implants in Routine Cochlear Implant Follow-up NCT06894303
Phase 1 · AeroRx Therapeutics · Phase 1 PK Study of AERO-007, an Inhaled LABA+LAMA Combination for Nebulization Delivery in COPD Patients NCT07802730
Phase 1 · Akebia Therapeutics · SAD and MAD Study of AKB-9090 in Healthy Adult Participants NCT07429006
Phase 3 · Aldeyra Therapeutics, Inc. · A Clinical Trial Evaluating Patients With Primary Vitreoretinal Lymphoma NCT07402876
Not applicable · Alpha Tau Medical · Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous SCC for Immunocompromised Patients NCT06615635
Not applicable · Alpha Tau Medical · Alpha Radiation Emitters Device for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia (DaRT) NCT03737734
Not applicable · Alpha Tau Medical · Alpha Radiation Emitters Device (DaRT) in Combination With Check Point Inhibitor for the Treatment of Recurrent Unresectable or mHNSCC NCT05047094
Phase 2 · Alto Neuroscience, Inc. · Study of ALTO-300 in MDD NCT05922878
Phase 1/Phase 2 · Alyssum Therapeutics · Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmocodynamics and Preliminary Antitumor Activity of AT-1965 in Patients With Advanced, Refractory or Recurrent Solid Tumors NCT06234098
Phase 1/Phase 2 · Alzamend Neuro · A Study to Investigate Lithium Brain/Plasma Pharmacokinetics and Safety of an AL001 Oral Capsule Compared to a Marketed Immediate-release Lithium Carbonate Capsule in Subjects With Bipolar I Disorder NCT07540338
Phase 2 · Amydis Diagnostics · A Study of AMDX-2011P in Participants With CAA NCT05709314
Not applicable · AngioDynamics · Acute Pulmonary Embolism Treatment With the AlphaVac Multipurpose Mechanical Aspiration System and the AlphaReturn Blood Management System: Evaluation of Safety and Effectiveness NCT07280247
Phase 2 · Angitia Biopharmaceuticals · A Trial Evaluating Efficacy of AGA2118 in PostMenopausal Women wIth Low Bone MasS (ARTEMIS) NCT06577935
Phase 1 · Arcus Biosciences · A Study to Investigate the Safety, Tolerability, and PK of AB102 in Healthy Participants NCT07662057
Phase 1 · Arrowhead Pharmaceuticals · Study of ARO-ATXN2 Injection in Adults With Spinocerebellar Ataxia Type 2 NCT06672445
Phase 2 · Ascentage Pharma · Study of APG-2575 in Patients With Relapsed/Refractory CLL/SLL NCT05147467
Phase 1 · Atea Pharmaceuticals · Study of AT-587 in Healthy Subjects NCT07728487
Phase 3 · Atea Pharmaceuticals · C-Forward: Efficacy and Safety of BEM/RZR vs SOF/VEL in Subjects With Chronic HCV NCT07037277
Phase 2 · Aveta Biomics · Safety and Efficacy of APG-157 in Head and Neck Cancer NCT05312710
Not applicable · Axogen · Tolerability and Feasibility Pilot Clinical Study of a Large-Diameter Nerve Cap for Protecting and Preserving Terminated Nerve Ends NCT04865679
Not applicable · Axogen · Nerve Protection Evaluation: Revision Cubital Tunnel Syndrome Decompression NCT06117501
Phase 3 · Axsome Therapeutics · Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol NCT06413433
Phase 3 · Axsome Therapeutics · Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN) NCT06568367
Phase 1/Phase 2 · Beam Therapeutics · A Study Evaluating the Safety and Efficacy of BEAM-201 in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LL) NCT05885464
Phase 1/Phase 2 · BioCardia · Clinical Trial of Human Allogenic Culture-expanded Bone Marrow-derived Mesenchymal Stem Cells NCT05925608
Phase 2/Phase 3 · Biohaven · A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy NCT06132893
Phase 2 · Biohaven · Long-term Safety and Tolerability of BHV-7000 NCT06443463
Not applicable · BiVACOR Inc. · BiVACOR® Total Artificial Heart Early Feasibility Study NCT06174103
Phase 2 · Brii Biosciences · Study to Investigate the Efficacy and Safety of Regimens Containing BRII-179, BRII-835, and PEG-IFNα Treating Chronic Hepatitis B Virus (HBV) Infection (ENRICH) NCT06491563
Not applicable · Capstan Medical · Capstan Medical TMVR Study: FIH NCT06600191
Phase 3 · Celltrion · Efficacy and Safety of Add-On Therapy With Empagliflozin in Patients With Type 2 Diabetes on a Background of Alogliptin and Metformin NCT07093476
Not applicable · Cilcare · Early Stage of Alzheimer's and Parkinson's Diseases, HearIng Relevance (SAPHIR) NCT07083089
Not applicable · Cognito Therapeutics · Extension to a Pivotal Study of Sensory Stimulation in Alzheimer's Disease (OLE Hope Study, CA-0015) NCT06245031
Phase 1 · Compass Therapeutics · A Phase 1 of CTX-8371 in Patients With Advanced Malignancies NCT06150664
Not applicable · Concept Medical · SirolimUs CoaTed Balloon for The TrEatment of Below The Knee Arterial Disease NCT04511247
Not applicable · CONMED · BioBrace® Implant for Arthroscopic Repair of Full Thickness Rotator Cuff Tears NCT05997381
Phase 1 · Context Therapeutics · CT-95 in Advanced Cancers Associated With Mesothelin Expression NCT06756035
Phase 3 · Cook MyoSite · Iltamiocel Compared to Placebo for Chronic Fecal Incontinence in Females With Obstetric Injury NCT05776277
Phase 2 · Corcept Therapeutics · Extension Study to Evaluate the Safety of Long-Term Use of Relacorilant in Patients With Cushing Syndrome NCT03604198
Phase 1 · Cullinan Therapeutics Inc. · A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus NCT06613360
Phase 1 · Deciphera Pharmaceuticals, LLC · Evaluate the Effect of Vimseltinib on P-glycoprotein (P-gp) Inhibition in Healthy Male Participants NCT07744802
Phase 2 · Delcath · Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients NCT06607458
Phase 1/Phase 2 · Denali Therapeutics · A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL593 in Healthy Participants and Participants With Frontotemporal Dementia (FTD-GRN) NCT05262023
Phase 1/Phase 2 · Design Therapeutics · A Multiple Ascending Dose Study of DT-216P2 in Patients With Friedreich's Ataxia NCT06874010
Phase 1 · Diakonos Oncology · Th-1 Dendritic Cell Immunotherapy Plus Standard Chemotherapy for Pancreatic Adenocarcinoma NCT04157127
Phase 2/Phase 3 · DiaMedica Therapeutics · Treatment of Acute Ischemic Stroke (ReMEDy2 Trial) NCT05065216
Phase 2 · Dianthus Therapeutics · A Clinical Study to Evaluate DNTH103 in Adults With Multifocal Motor Neuropathy NCT06537999
Phase 1 · Dragonfly Therapeutics · A Study to Evaluate the Safety of Increasing Doses of DF5112 in Healthy Adults NCT07232121
Phase 1/Phase 2 · Dren Bio · A Study of DR-01 in Subjects With Large Granular Lymphocytic Leukemia or Cytotoxic Lymphomas NCT05475925
Phase 1 · DynamiCure · DCSZ11 as a Monotherapy and in Combination in Patients With Advanced or Metastatic Solid Tumors NCT05785754
Phase not stated · Edwards Lifesciences · Real World Data Collection on the INSPIRIS RESILIA Aortic Valve NCT07120048
Not applicable · Edwards Lifesciences · COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction NCT02744677
Phase 2 · Eikon Therapeutics · A Phase 2 Study of EIK1001 in Combo With Pembrolizumab and Chemotherapy in Patients With Stage 4 NSCLC NCT06246110
Phase not stated · Elephas Biosciences · Observational Lung Trial to Collect Tissue to Train and Validate a Live Tumor Diagnostic Platform (ELEPHAS-01) NCT05478538
Phase 1 · Eli Lilly · A Study of LY4515100 in Healthy Male Participants NCT07867327
Phase 2 · Eli Lilly · A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer NCT07169851
Phase 2 · Elion Therapeutics · Phase 2 EL219 Versus Liposomal Amphotericin B or Voriconazole for Early Antifungal Therapy NCT07215273
Phase 2 · Enanta Pharmaceuticals · A Phase 2 Study to Investigate the Efficacy and Safety of Zelicapavir in Participants Aged ≥28 Days to ≤36 Months of Age Infected With Respiratory Syncytial Virus NCT07482657
Not applicable · EnCompass Technologies · Trial of the F2 Filter and Delivery System for Embolic Protection During TAVR NCT06689839
Phase not stated · Ensoma · Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease NCT06605378
Not applicable · Fresenius Kabi · Glycaemic Index Measurement of an Oral Nutritional Supplement With Biomarker Assessment and Lifestyle Monitoring in Healthy Participants NCT07479251
Phase 3 · Genelux · Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-30 NCT05281471
Phase 1/Phase 2 · Georgiamune · Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors NCT06425926
Phase 1 · HDT Bio Corp. · Safety and Immunogenicity of a Self-Amplifying RNA Vaccine Against Crimean-Congo Hemorrhagic Fever NCT06799013
Not applicable · Healionics Corporation · STARgraft (10401) Pilot NCT07555717
Phase 1 · HiFiBiO Therapeutics · A Study of HFB200603 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors NCT05789069
Phase 1 · HiFiBiO Therapeutics · A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors NCT05238883
Not applicable · Ideal Medical Technologies · Closed Loop Glucose Control in a Simulated ICU Setting NCT07646067
Phase not stated · IlluminOss Medical · Device Global Registry for the IlluminOss Bone Stabilization System NCT05206981
Phase 2 · Imbria Pharmaceuticals · A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy NCT07023614
Phase 1/Phase 2 · Ingenia Therapeutics · A Study to Investigate IGT-303 in Healthy Volunteers and Participants With Chronic Kidney Disease NCT07231679
Not applicable · Insightec · ExAblate (Magnetic Resonance-guided Focused Ultrasound Surgery) Treatment of Brain Tumors NCT01473485
Not applicable · Insightec · Blood-Brain Barrier Disruption Using Transcranial MRI-Guided Focused Ultrasound NCT02343991
Not applicable · Insightec · MRI-Guided Focused Ultrasound Feasibility Study for Brain Tumors NCT00147056
Phase 2 · jCyte · Safety of a Single, Intravitreal Injection of 6.0M jCell (Famzeretcel) in Retinitis Pigmentosa (RP) NCT06912633
Phase 2 · Kardigan · Study of Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe Hypertension NCT07511361
Phase 2/Phase 3 · Karyopharm Therapeutics Inc. · A Study of Rituximab-Gemcitabine-Dexamethasone-Platinum (R-GDP) With or Without Selinexor in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma NCT04442022
Phase 2 · Karyopharm Therapeutics Inc. · Selinexor (KPT-330) in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL) NCT02227251
Phase 1 · Krystal Biotech · A Study Assessing KB407 for the Treatment of Cystic Fibrosis NCT05504837
Phase 3 · Krystal Biotech · A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis Bullosa NCT07016750
Phase 1/Phase 2 · Krystal Biotech · A Study Comparing KB801 Verse Placebo in Patients With Stage 2 or 3 Neurotrophic Keratitis NCT06999733
Phase 1 · Kura Oncology · Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia NCT06001788
Phase 1 · Kymera Therapeutics, Inc. · First-in-human Study of Orally Administered KT-579 in Healthy Adult Participants NCT07412288
Phase 2 · Lantern Pharma · A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma NCT05456256
Phase 1/Phase 2 · Lexeo Therapeutics · Gene Therapy for ACM Due to a PKP2 Pathogenic Variant NCT06109181
Phase 1/Phase 2 · Lumicell, Inc. · Feasibility of the LUM Imaging System for Detection of Gastrointestinal Cancers NCT02584244
Phase 3 · Madrigal Pharmaceuticals · A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES) NCT05500222
Phase 1 · MediBeacon Inc. · Evaluation of Lumitrace for Visualizing Ureters During Abdominopelvic Surgeries NCT07080008
Early phase 1 · MediBeacon Inc. · Feasibility and Safety of MB-102 in Ocular Angiography as Compared to Fluorescein Sodium NCT04008121
Phase 1 · Medley Therapeutics · Study Assessing Left Ventricular Administration of a Genetic Medicine Directing Organ Regeneration in Heart Failure NCT06831825
Phase 1 · Monopar Therapeutics · Diagnostic Efficacy and Dosimetry of MNPR-101-DFO*-89Zr in Patients With Solid Tumors NCT06337084
Phase 1/Phase 2 · Nexcella · Study of NXC-201 CAR-T in Patients With Light Chain (AL) Amyloidosis NCT06097832
Not applicable · Noctrix Health, Inc. · Optimizing Extended-Duration (XD-) TOMAC Therapy for Restless Legs Syndrome (RLS) NCT07675109
Phase 2 · NS Pharma, Inc. · Trial of Efficacy and Safety of NS-229 Versus Placebo in Patients With Eosinophilic Granulomatosis With Polyangiitis NCT06046222
Phase 1 · Nuvectis Pharma · Study of NXP900 With Osimertinib in Subjects With Advanced, EGFR-Mutated Non-Small Cell Lung Cancer NCT07315113
Phase 1 · NuvOx Therapeutics · A Dose Escalation Study of NanO2 in Patients With Mild Respiratory Distress NCT06658535
Phase 2 · Omeros · Long-Term Safety, Tolerability and Efficacy of OMS906 in Paroxysmal Nocturnal Hemoglobinuria NCT06298955
Phase 1 · ORIC Pharmaceuticals · ORIC-114 in Combination With Subcutaneous Amivantamab in Patients With EGFR Exon20 Insertion Mutant NSCLC NCT06816992
Phase 3 · Otsuka · A Phase 3 Trial to Demonstrate the Superiority of 1% OPA-15406 Foam to the Vehicle in Adult Patients With Atopic Dermatitis NCT07173478
Phase 1 · PanTher Therapeutics · PTM-101 in Pancreatic Ductal Adenocarcinoma (PDAC) NCT06673017
Phase not stated · Penumbra · Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System NCT04798261
Not applicable · Phantom Neuro · Evaluation of the Phantom X Implantable EMG Sensor System for Myoelectric Prosthesis Control NCT07325708
Phase 3 · Praxis Precision Medicines · A Clinical Trial for Participants With DEE to Assess Efficacy, Safety, Tolerability, and PK of Relutrigine NCT07010471
Phase 3 · Praxis Precision Medicines · A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety NCT07019922
Phase 1 · Precision BioSciences · Phase 1 Study to Evaluate Safety and Antiviral Activity of PBGENE-HBV in Adult Patients With Chronic Hepatitis B NCT06680232
Phase not stated · PreludeDx · The PREDICT Registry: NCT03448926
Phase 1 · ProMIS Neurosciences · PMN310 in Patients With Early Alzheimer's Disease (PRECISE-AD) NCT06750432
Phase 2 · Protara Therapeutics · Safety and Efficacy Study of Intracystic TARA-002 for the Treatment of Lymphatic Malformations in Participants 6 Months to Less Than 18 Years of Age NCT05871970
Phase 2 · Pulmovant · A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD NCT07333183
Early phase 1 · Ratio Therapeutics · A Study of the Pharmacokinetics, Biodistribution and Dosimetry of Granzyme-B Targeted [Cu-64]-Labeled PET Radiotracers in Adult Healthy Volunteers NCT07774650
Phase 3 · RayzeBio · Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy NCT05477576
Phase 1 · ReacX Pharmaceuticals · Nalmefene Implant in Healthy Subjects NCT07325279
Phase 1 · Sapience Therapeutics · A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors NCT04478279
Not applicable · SeaStar Medical · Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - A Randomized Clinical Trial in Acute Kidney Injury NCT05758077
Phase 3 · Sound Pharmaceuticals, Incorporated · SPI-1005 for the Treatment of Meniere's Disease (Open Label) NCT06859788
Phase 2 · Sound Pharmaceuticals, Incorporated · SPI-1005 in Adults Receiving Cochlear Implant NCT06340633
Not applicable · Spinal Simplicity · Post-Market Clinical Study of Functional Motion Outcomes in Subjects Treated With the Minuteman Device NCT06355791
Phase 1/Phase 2 · Stemline Therapeutics · Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer NCT05386108
Not applicable · Supira Medical · Feasibility Study of the Supira System in Patients Undergoing HRPCI With Support Beyond the PCI Procedure NCT07407816
Phase 1/Phase 2 · SynDevRx · Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer NCT05455619
Phase 2 · Taiho Oncology · Study of Futibatinib in Patients With Advanced Cholangiocarcinoma With FGFR2 Fusion or Rearrangement NCT05727176
Phase 1 · Taiho Oncology · Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Renal Impairment NCT04953897
Phase 1 · Taiho Oncology · Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Hepatic Impairment NCT04953910
Phase 1 · Trellis Bioscience · Study to Evaluate Safety and Activity of Inhaled TRL1068 in Healthy Volunteers NCT07644195
Phase 3 · United Therapeutics · A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension NCT03683186
Phase 3 · Vanda Pharmaceuticals · Study to Evaluate the Efficacy and Safety of VQW-765 for the On-Demand Treatment of Social Anxiety Disorder NCT07221578
Phase 3 · Veradermics · Safety and Efficacy of VDPHL01 in Males With AGA NCT06972264
Phase 3 · Vir Biotechnology · A Study to Evaluate Tobevibart+Elebsiran in Participants With Chronic HDV Infection Not Virologically Suppressed With Bulevirtide NCT07128550
Phase 1 · Vivani Medical · Safety, Tolerability and Pharmacokinetics of a Subcutaneous Semaglutide Implant NCT07430059
Phase 2 · Zenith Epigenetics · ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer NCT04986423
Phase not stated · Zimmer Biomet · Database Retrieval for the Comprehensive Shoulder NCT03409718
Phase not stated · Zimmer Biomet · Persona IQ Cohort Study NCT06089291
Phase not stated · Zimmer Biomet · Outcomes Study of the Trabecular Metal (TM) Reverse Shoulder System NCT01480440
Phase 1 · Zumutor Biologics · This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors NCT06451497
Phase 2 · Biocomposites · A Randomized Controlled Phase II Trial of STIMULAN VG vs Standard of Care (SoC) for the Treatment of Osteomyelitis Associated With Stage IV Pressure Ulcers. NCT06283979
Phase 3 · Biogen · A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Kidney Transplants Who Have Antibody-Mediated Rejection (AMR) NCT06685757
Phase 2 · Cartesian Therapeutics Inc. · Descartes-08 for Patients With Systemic Lupus Erythematosus NCT06038474
Not applicable · Concept Medical · Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease NCT06182397
Not applicable · ConvaTec · EDX110 Randomized Control Trial for Treatment of DFUs NCT07209358
Phase not stated · Eko Devices · Data Collection Using Eko Devices in a Clinical Setting NCT07270744
Phase 2 · EpicentRx · A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid Tumors NCT04673942
Not applicable · Kubota Vision · A Controlled Evaluation of Optical Defocus Parameters on Transient Changes in Axial Length Using Kubota Glass NCT07686289
Phase 1/Phase 2 · Luxa Biotechnology · Safety and Tolerability of RPE Stem Cell-derived RPE(RPESC-RPE) Transplantation in Patients With Dry Age-related Macular Degeneration (AMD) NCT04627428
Not applicable · Navigantis · Robot-Assisted Neurovascular Intervention NCT06752096
Phase not stated · Nihon Kohden · Pulse Oximeter Accuracy During Stable Hypoxia Plateaus NCT07408388
Phase not stated · Novo Nordisk A/S · Adverse Event Data Collection From the EUHASS Registry on Turoctocog Alfa Pegol NCT04682145
Phase not stated · Rani Therapeutics · An Early Phase Study of RT-114 (RaniPill Containing PG-102, a GLP-1/2 Dual Agonist) in Healthy Volunteers. NCT06891287
Phase 3 · Vanda Pharmaceuticals · A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist Use NCT07446439
Phase 1 · Shionogi · Study of Sulthiame (S-054502) in Participants With Renal Impairment and Matched Healthy Controls NCT07857837
Phase 1 · Excellergy · A Study to Find a Suitable Dose of Exl-111 for Further Research NCT07356713
Phase 1 · Novartis · A Safety and Tolerability Study of HJB647 in Heart Failure Participants With Reduced Ejection Fraction NCT07465653
Not applicable · SetPoint Medical · Long Term Extension of Safety and Efficacy of Vagus Nerve Stimulator in Patients With Rheumatoid Arthritis (RA) NCT04862117
Phase 1 · Incyte · Study to Evaluate the Maximal Use of Ruxolitinib Cream in Adult and Adolescent Participants With Hidradenitis Suppurativa NCT07049575
Phase 3 · Boehringer Ingelheim · Beamion LUNG-2: A Study to Test Whether Zongertinib (BI 1810631) Helps People With Advanced Non-small Cell Lung Cancer With HER2 Mutations Compared With Standard Treatment NCT06151574
Phase not stated · Lineage Cell Therapeutics · LTFU Study of Subjects Who Received GRNOPC1 NCT05919563
Phase 1 · Bristol-Myers Squibb · A Study to Evaluate the Pharmacokinetics and Safety of Golcadomide in Participants With Severe Renal Impairment and End-Stage Renal Disease Compared With Participants With Normal Renal Function NCT07763418
Phase 3 · Alexion Pharmaceuticals, Inc. · PK, PD, Safety, and Efficacy Study of Gefurulimab in Pediatric Patients With AChR+ Generalized Myasthenia Gravis NCT06607627
Not applicable · AnX Robotica · NaviCam Patency Capsule to Verify Gastrointestinal Patency NCT07649720
Phase 2 · Cerus · A Recovery and Lifespan Study Using INTERCEPT Red Blood Cells Prepared Using the INTERCEPT Blood System for RBCs With AS-1 NCT07015437
Phase 3 · Exelixis · Study of XL092 + Nivolumab vs Sunitinib in Subjects With Advanced or Metastatic Non-Clear Cell Renal Cell Carcinoma NCT05678673
Phase 1/Phase 2 · GV20 Therapeutics · A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies NCT05669430
Phase 3 · Ipsen · A Study to Assess the Effectiveness and Safety of IPN10200 Over Time in Adults With Moderate to Severe Wrinkle-like Lines Between the Eyebrows NCT07435428
Phase 3 · Ipsen · A Study to Assess the Effectiveness and Safety of IPN10200 in Adults With Moderate to Severe Wrinkle-like Lines Between the Eyebrows NCT07427797
Phase not stated · Novartis · A Study of Complement 3 Glomerulopathy (C3G) Patients Treated With Iptacopan Through an Early Access Program in Spain NCT07598448
Phase not stated · Novartis · A Study of Patients' Preferences for Primary Immune Thrombocytopenia Treatment NCT07786077
Phase 1 · PAQ Therapeutics · A Study of PT0253 in Participants With KRAS G12D Mutated Advanced Solid Tumors NCT06797336
Phase 1 · Moderna · A Study to Investigate Safety and Tolerability of mRNA-0184 Administered Subcutaneously in Healthy Participants NCT06655870
Phase 3 · Ipsen · A Study of Elafibranor in Adult Japanese Participants With Primary Biliary Cholangitis (PBC) NCT06730061
Phase 2 · Sanofi · A Study to Investigate the Efficacy and Safety of Brivekimig in Adult Participants With Ulcerative Colitis NCT06975722
Phase 1 · Scholar Rock, Inc. · A Single- and Multiple-Ascending Dose Study of SRK-439 in Healthy Adults NCT07444294
Phase 1 · Novartis · Assessment of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of a New Formulation of Inclisiran Containing Polysorbate 80 Compared to the Currently Marketed Formulation NCT07626281
Phase 3 · Adverum Biotechnologies · Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-Related Macular Degeneration NCT06856577
Phase 1 · Boehringer Ingelheim · A Study to Test How Well Different Doses of BI 3034701 Are Tolerated by Japanese Healthy People and Japanese People With Obesity or Overweight NCT07693231
Phase 2 · Boehringer Ingelheim · A Study to Test Different Doses of BI 1584862 in People With a Distinct Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy NCT06769048
Phase 1 · Ensysce Biosciences · Single Dose Study, Pharmacokinetics of Oxycodone and PF614 Co-Administered With Nafamostat (PF614-MPAR-102) NCT06500793
Phase 1 · Alexion Pharmaceuticals, Inc. · Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study of ALXN2230 in Healthy Participants NCT07352423
Phase 1 · Boehringer Ingelheim · A Study to Test How BI 1291583 is Taken up in the Blood of People With and Without Liver Problems NCT07023354
Phase 2 · Sanofi · A Study to Evaluate the Efficacy and Safety of Frexalimab, Brivekimig, or Rilzabrutinib in Participants Aged 16 to 75 Years With Primary Focal Segmental Glomerulosclerosis or Minimal Change Disease NCT06500702
Phase 1 · Bayer AG · A Study to Learn About How Safe BAY 3389934 is, Its Suitable Dose, and How it Affects the Participants With Sepsis Induced Coagulopathy NCT06854640
Phase 1 · QuantX Biosciences · A Single and Multiple Ascending Dose Escalation and Food Effect Study of QX-4533 in Healthy Participants NCT07678463
Phase 3 · Incyte · A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa NCT06212999
Phase not stated · Novo Nordisk A/S · Patient Preferences in Treatment of Haemophilia A With and Without Inhibitors: a Discrete Choice Experiment in Germany NCT07653139
Phase 2 · Amplexd Therapeutics · Phase II Study of Dysplasix™ Intravaginal Suppositories in Patients Patients With High-Risk HPV and Mild Cervical Cytologic Abnormalities NCT07572396
Phase 1/Phase 2 · Stemline Therapeutics · Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Participants With Metastatic Breast Cancer NCT05563220
Phase 1 · Alnylam Pharmaceuticals · A Study to Evaluate ALN-4285 in Adult Healthy Volunteers NCT07295717
Phase 1 · Alterome Therapeutics · A Study to Learn About Study Medicine ALTA2618 in Adults With AKT1 E17K-Mutant Solid Tumors NCT06533059
Phase 1 · Bayer AG · A Study to Learn About How Safe BAY3389934 is and How it Affects Blood Clotting When Given Alone or With Aspirin in Healthy Participants NCT07652723
Phase 1 · Dr. Reddy's Laboratories · A Study to Evaluate Pharmacokinetics of DRL_AB in Healthy Male Participants NCT07744828
Phase 1 · Akamis Bio · NG-350A Plus Chemoradiotherapy for Locally Advanced Rectal Cancer NCT06459869
Phase 2 · Allotera Therapeutics · A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex) NCT06514794
Not applicable · Andromeda Surgical · A Prospective, Multicenter, Open-label Study of the Beacon Platform for Holmium Laser Enucleation of the Prostate (HoLEP) NCT06668142
Phase not stated · Anebulo Pharmaceuticals · Observational Study of THC Concentrations in Acute Cannabis-induced CNS Depression NCT06017622
Phase 3 · Askgene Pharma · ASKB589 in Combination With CAPOX and PD-1 Inhibitor in Patients With Advanced or Metastatic GC/GEJ Adenocarcinoma NCT06206733
Phase 1/Phase 2 · Bionic Sight · BS01 in Patients With Retinitis Pigmentosa NCT04278131
Phase not stated · Bluejay Diagnostics · Multicenter Symphony™ IL-6 Monitoring Sepsis ED Pilot Study NCT07425587
Phase 1 · Boehringer Ingelheim · Beamion LUNG-1: A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene) NCT04886804
Phase 3 · Cartesian Therapeutics Inc. · Investigating an mRNA CAR T-cell Therapy, Known as Descartes-08, as a Potential Approach to Treat Myasthenia Gravis NCT06799247
Early phase 1 · Cyclarity Therapeutics · Placebo-controlled Study of Single and Multiple Ascending Doses of UDP-003 in Healthy Human Participants and Followed by an Open-label Patient Cohort NCT06813339
Phase 1 · Daiichi Sankyo · A Study of DS-6000a in Subjects With Advanced Renal Cell Carcinoma and Ovarian Tumors NCT04707248
Not applicable · Insightec · Continued Access of Focal MR-Guided Focused Ultrasound for Localized Intermediate Risk Prostate Lesions NCT03998657
Phase 2 · NeOnc Technologies · NEO100 and High-Grade Meningioma NCT05023018
Phase 2/Phase 3 · Quoin Pharmaceuticals · Clinical Study of QRX003 Lotion in Subjects With Netherton Syndrome NCT06953466
Phase 2/Phase 3 · Quoin Pharmaceuticals · Open Label, Safety and Efficacy Study of QRX003 Lotion in Subjects With Netherton Syndrome NCT05789056
Not applicable · Rhaeos, Inc. · A Prospective Study Comparing CSF Shunt Flow Between "Virtual Off" and "Flow Permissive" Shunt Valve Settings Using a Wireless, Noninvasive Shunt Flow Sensor NCT07815314
Phase 1/Phase 2 · Sellas Life Sciences Group · Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML NCT04588922
Phase 2 · Shionogi · A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease NCT07214571
Phase 1/Phase 2 · Supernus Pharmaceuticals · BIS-001-ER for the Treatment of Adult Focal Impaired Awareness Seizures NCT03474770
Phase 2 · Swedish Orphan Biovitrum · A Study to Assess the Effectiveness and Safety of Pacritinib in Patients With VEXAS Syndrome (PAXIS) NCT06782373
Phase 2 · Teclison · Combination of TATE and PD-1 Inhibitor in Liver Cancer NCT03259867
Phase 1 · TScan Therapeutics · A Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid Tumors NCT05973487
Phase 2 · XyloCor Therapeutics Inc. · Epicardial Delivery of XC001 Gene Therapy to Promote Angiogenesis in CAD Patients Undergoing Treatment With CABG NCT07118449
Phase 1 · Acepodia · ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR) NCT06415487
Not applicable · Advanced Bionics · Hearing and Structure Preservation Via ECochG NCT06268340
Phase 1 · AgonOx, Inc. · Adoptive Cell Therapy Using Cancer Specific CD8+ Tumor Infiltrating Lymphocytes in Adult Patients With Solid Tumors NCT05902520
Not applicable · Align Technology · Invisalign® System with Mandibular Advancement NCT06651944
Phase 3 · Amicus Therapeutics · A Study to Evaluate Migalastat in Fabry Subjects With Amenable GLA Variant and Renal Disease NCT04020055
Phase 2/Phase 3 · AMO Pharma · Safety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic Dystrophy NCT05004129
Not applicable · Andromeda Surgical · A Study of the Beacon Platform for Holmium Laser Enucleation of the Prostate (HoLEP) NCT07741656
Phase 3 · Annexon Biosciences · An Open Label Clinical Study to Evaluate Tanruprubart (Also Commonly Known as ANX005) in Participants With Guillain-Barré Syndrome (FORWARD Study) NCT07020819
Not applicable · Apyx Medical · Within-Subject Comparison of Adipose Tissue Viability Following Liposuction NCT07820397
Not applicable · Aqua Medical · A U.S. Pilot Human Investigation of RadiofrEquency Vapor Ablation System to Evaluate Safety, TOleRability, and Effectiveness for Proximal Intestinal Mucosal Ablation in Patients With Type 2 Diabetes M NCT07355270
Phase 3 · Ascentage Pharma · Global Trial in APG2575 for Patients With CLL/SLL NCT06104566
Phase 1/Phase 2 · Askgene Pharma · A Study of ASKG915 in Patients With Selected Advanced Solid Tumors. NCT05867420
Phase 1/Phase 2 · Aveta Biomics · Treatment of Patients With Recurrent High-Grade Glioma With APG-157 and Bevacizumab NCT06011109
Phase 1 · Bambusa Therapeutics · A Study of BBT002 in Healthy Volunteers (HVs) and in Patients With Chronic Obstructive Pulmonary Disease (COPD) NCT07288554
Phase not stated · Bluejay Diagnostics · Multicenter Symphony IL-6 Monitoring Sepsis ICU Validation Study NCT06654895
Phase 3 · Boehringer Ingelheim · EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin) NCT06531824
Not applicable · Cardiac Dimensions · The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR NCT03142152
Phase 1 · CARsgen Therapeutics · CT011 Autologous CAR-T Cells in Patients With Hepatocellular Carcinoma at Risk of Recurrence After Surgical Resection NCT06560827
Phase 1 · CARsgen Therapeutics · A Study to Evaluate the Efficacy and Safety of CT041 After Adjuvant Chemotherapy for Pancreatic Cancer NCT05911217
Phase not stated · CathVision · Measuring Local Potentials in PFA. MULTI PFA (EU) NCT07379697
Phase not stated · Ceribell · EEG Abnormalities in Adult ICU Patients With High Risk of Delirium NCT07485244
Not applicable · CoreMap · Endocardial Mapping With the CoreMap EP Mapping System NCT06529978
Phase 3 · Corza Medical · A Study to Compare the Efficacy and Safety of TachoSil and Surgicel Original as an Adjunct to Control Mild to Moderate Soft Tissue Bleeding During Surgery NCT06664775
Not applicable · EchoPixel · EPX-HTG for Structural Heart Procedures NCT07705425
Not applicable · Edwards Lifesciences · Clinical Study of Edwards Cardioband FIT Valve Repair System NCT03382457
Phase 1/Phase 2 · Evopoint Biosciences · Study of XNW28012 in Subjects With Advanced Solid Tumors Who Failed Standard Treatments NCT06799637
Not applicable · ExThera Medical · Blood Purification for the Treatment of Pathogen Associated Shock NCT05011656
Phase 1 · Forte Biosciences · A Study to Evaluate the Safety and Efficacy of FB102 in Patients With Non-segmental Vitiligo NCT06905873
Phase not stated · Guardant Health · Screening for High Frequency Malignant Disease NCT05117840
Phase not stated · HeartFlow · Using CTA Measures to Define Cardiac Risk In NFL Alumni NCT06831409
Phase 2 · Hillhurst Biopharmaceuticals · Low-dose Carbon Monoxide (HBI-002) Trial to Evaluate Safety, Tolerability, PK, and Biomarkers in Parkinson's Disease NCT07005180
Phase 1/Phase 2 · Inovio Pharmaceuticals · INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM) NCT03491683
Not applicable · Insightec · A Feasibility Safety Study of Benign Centrally-Located Intracranial Tumors in Pediatric and Young Adult Subjects NCT03028246
Not applicable · Insightec · Exablate for LIFU Neuromodulation in Patients With Opioid Use Disorder (OUD) and/or Other Substance Use Disorders (SUDs) NCT04197921
Phase not stated · Insightec · Post-Exablate Pregnancy Outcomes Registry Study: Exablate Treatment of Symptomatic Uterine Fibroids NCT05386615
Phase 2/Phase 3 · Insmed · An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Arterial Hypertension (PAH) NCT05649748
Not applicable · Integra LifeSciences · A Modified Platform Trial of Multiple CAMPs for the Management of Diabetic Foot Ulcers and Venous Leg Ulcers NCT06453187
Phase 2 · Jazz Pharmaceuticals · A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors NCT06695845
Phase 1/Phase 2 · Kamau Therapeutics · Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease NCT04819841
Phase 3 · Kartos Therapeutics · Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib NCT06479135
Phase 1 · Kumquat Biosciences · A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies NCT06507306
Phase not stated · Luminopia · Clinical Data Registry of Amblyopia Patients on Luminopia Treatment NCT06429280
Not applicable · Masimo · Philips FAST SpO2 Technology With Masimo Sensors for SpO2 Monitoring in the Neonatal, Infant, and Pediatric Populations NCT07223177
Phase 1 · MBQ Pharma · A Study of Oral MBQ-167 in Participants With Advanced Breast Cancer NCT06075810
Phase 2 · MediciNova · MN-001 in Non-alcoholic Fatty Liver Disease, Type 2 Diabetes Mellitus, and Hypertriglyceridemia NCT05464784
Phase 2 · Mercator MedSystems, Inc. · Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Acute Femoropopliteal DVT NCT04862468
Phase 4 · Moderna · A Study to Investigate the Immunogenicity and Safety of mRNA COVID-19 Variant-containing Vaccine Formulations NCT06585241
Not applicable · Novian Health · Confirmatory Clinical Evaluation of Novilase® Laser Therapy for Focal Destruction of Malignant Breast Tumors NCT03463954
Phase 2/Phase 3 · Olatec Therapeutics · Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare NCT05658575
Phase 1/Phase 2 · OncoC4 · Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC NCT04140526
Phase 1 · Oxford BioTherapeutics · Safety and Preliminary Efficacy of OBT076 in Recurrent/Metastatic CD205+ Solid Tumors NCT04064359
Phase 2 · Partner Therapeutics · A Study of Zenocutuzumab (MCLA-128) in Patients With Solid Tumors Harboring an NRG1 Fusion (eNRGy) NCT02912949
Phase not stated · Pulmonx · Zephyr Valve Registry (ZEVR) NCT04186546
Not applicable · Pulse Biosciences, Inc. · CellFX® nsPFA™ Cardiac Surgery System to Treat Atrial Fibrillation NCT06355063
Not applicable · R3 Vascular · Evaluation of the MAGNITUDE® Bioresorbable Drug-Eluting Scaffold in the Treatment of Patients With Below the Knee Disease in Australia NCT06075940
Not applicable · R3 Vascular · Study of the R3 Vascular Drug-Eluting Bioresorbable Scaffold in Treating Below the Knee Arterial Disease NCT04912323
Phase 1 · Radiomedix, Inc. · Study of 203Pb-RMX-VH-PIB Dosimetry and Biodistribution in Patients With Glioblastoma Multiform (GBM) and Pancreatic Ductal Adenocarcinoma (PDAC) NCT07733674
Not applicable · Regenexx · Trial for Treating Painful Degenerative Disc Disease NCT05287867
Phase 1 · REVOLUTION Medicines · Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors NCT06040541
Not applicable · Rhaeos, Inc. · Flow Detection in Open and Closed Shunt Valve Periods NCT07478926
Phase not stated · Sanguine Biosciences · A Multi-Site Leukopak Repository Providing Annotated Biospecimens for Approved Investigator-Directed Biomedical Research Initiatives NCT05794217
Phase 2 · Sano Chemicals Inc · Biweekly Long-term Occidiofungin Study for Suppression of Mycotic Recurrence NCT07521137
Phase 1 · Sapience Therapeutics · A Phase 1-2 of ST316 With Selected Advanced Unresectable and Metastatic Solid Tumors NCT05848739
Phase 1/Phase 2 · Sarepta Therapeutics, Inc. · Study of SRP-1003 in Participants With Type 1 Myotonic Dystrophy NCT06138743
Phase 2 · Shionogi · Safety and Efficacy Study of Sivopixant, Acetazolamide and SASS-001 in Sleep Apnea NCT06776432
Phase 1 · Solu Therapeutics · A Phase 1 Study of STX-0712 in Patients With Advanced Hematological Malignancies (CMML and AML) NCT06950034
Phase 1 · Spirovant Sciences · A Phase 1/2 Trial of SP-101 for the Treatment of Cystic Fibrosis (CF) NCT06526923
Phase 2 · Supernus Pharmaceuticals · Double-blind, Placebo-controlled Study in Adults With Major Depressive Disorder NCT07226661
Phase not stated · Takeda · A Study of NINLARO® in Chinese Adults With Multiple Myeloma NCT05013190
Phase not stated · Takeda · A Study of OBIZUR in Adults With Acquired Hemophilia A (AHA) in South Korea NCT06550882
Phase 2 · Tarsus Pharmaceuticals · Study of Lotilaner Ophthalmic Gel in Patients With Ocular Rosacea (KORE) NCT07443202
Phase 1 · Trethera · Open-Label, Dose-Escalation With Expansion to Assess the Safety, Tolerability, and PK of TRE-515 in Subjects With Solid Tumors NCT05055609
Phase 1 · Unravel Biosciences · An Exploratory Evaluation of the Safety and Efficacy of Vorinostat in Pitt Hopkins Syndrome NCT07150026
Phase 1 · Unravel Biosciences · Rett REVOLUTION Trial: An Exploratory Evaluation of the Safety and Efficacy of Vorinostat in Rett Syndrome NCT07150013
Phase not stated · Vertex Pharmaceuticals Incorporated · Polycystic Kidney Disease 1 (PKD1) Gene Variant Groups in Autosomal Dominant Polycystic Kidney Disease NCT06747572
Not applicable · Vesalio · NeVa ONE Registry Study NCT04562194
Phase 3 · Vir Biotechnology · A Study to Evaluate Tobevibart + Elebsiran in Chronic HDV Infection NCT06903338
Phase 1 · Zydus Therapeutics · Hepatic Impairment With Cirrhosis Due to Cholestatic Liver Disease NCT05045482
Phase 1 · Zydus Therapeutics · Evaluate PK & Safety of Saroglitazar in Subjects With Moderate Hepatic Impairment Due to Cholestatic Liver Disease NCT06825559

Jan 2027 (estimated) · 105 trials

Phase 2 · Actio Biosciences · A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Clinical Activity of ABS-1230 in Pediatric and Young Adult Participants With KCNT1-related Epilepsy NCT07600736
Not applicable · Alpha Tau Medical · Alpha Radiation Emitters Device (DaRT) for the Treatment of Locally Advanced Pancreatic Cancer NCT06755359
Not applicable · Alpha Tau Medical · Alpha Radiation Emitters Device (DaRT) for the Treatment of of Malignant Cutaneous Tumors NCT04068155
Not applicable · Alpha Tau Medical · Alpha Radiation Emitters for the Treatment of Pancreatic Cancer for the Treatment of Locally Advanced Pancreatic Cancer NCT06026943
Phase 2 · Arcus Biosciences · A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies NCT05329766
Not applicable · Becton Dickinson · Personal BP - CAI Study NCT06492746
Not applicable · Becton Dickinson · The Continuity Study NCT07216573
Phase 2 · BioMendics · A Phase II, Placebo Controlled, Clinical Trial of Topical TolaSure Targeting Aggregated Mutant Keratin in Epidermolysis Bullosa Simplex NCT07027345
Phase 1 · Centrexion Therapeutics · Safety and PK of Intrathecal CNTX-3001 for Intractable Chronic Low Back Pain NCT07122453
Not applicable · Checkpoint Surgical · Evaluating Therapeutic Electrical Stimulation to Improve Nerve Healing After Surgical Repair of Digital Nerve Injuries NCT06867185
Phase 2/Phase 3 · Coya Therapeutics · Study of COYA 302 for the Treatment of ALS NCT07161999
Phase 1 · Crossbow Therapeutics · A Study of CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias NCT06994676
Phase 1 · Cullinan Therapeutics Inc. · CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) NCT05143996
Phase 2 · Edgewise Therapeutics · A Study of EDG-5506 in Children With Duchenne Muscular Dystrophy (LYNX) NCT05540860
Phase 1/Phase 2 · Eledon Pharmaceuticals · Safety, Pharmacokinetics, and Efficacy of AT 1501 in Patients Undergoing Kidney Transplant NCT05027906
Phase not stated · Elephas Biosciences · Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform (ELEPHAS-02) NCT05520099
Phase 1 · Eli Lilly · A Study of Single and Multiple Doses of LY5625573 in Healthy Participants, Including Japanese and Chinese Populations, and Participants With Inflammation (High C-Reactive Protein) NCT07867340
Phase 1 · Eli Lilly · A Study of LY4355756 in Healthy Participants NCT07765498
Phase 1 · Enliven Therapeutics · ELVN-002 With Trastuzumab +/- Chemotherapy in HER2+ Solid Tumors, Colorectal and Breast Cancer NCT06328738
Phase 2 · Evopoint Biosciences · To Evaluate XNW5004 Tablets in Patients with Relapsed or Refractory Peripheral T Cell Lymphoma NCT06702605
Phase 2 · Gilead · Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis NCT06029972
Phase 2 · Imvax · A Phase 2b Clinical Study With a Combination Immunotherapy in Newly Diagnosed Patients With Glioblastoma NCT04485949
Phase 1 · Kura Oncology · KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors NCT06026410
Phase 2 · Lakewood-Amedex · Phase 2a Dose Finding Study of Nu-3 Gel in Subjects With Mild iDFU NCT07565506
Phase 2 · Larimar Therapeutics · An Open-Label Study of CTI-1601 in Subjects With Friedreich's Ataxia NCT06447025
Phase 1/Phase 2 · Marengo Therapeutics · A Study of Invikafusp Alfa (STAR0602), a Selective T Cell Receptor (TCR)-Targeting, Bifunctional Antibody-fusion Molecule, in Combination With Sacituzumab Govitecan in Participants With Advanced Solid NCT06827613
Not applicable · MediBeacon Inc. · Evaluation of Protein Loading on Measurement of Renal Reserve NCT07335614
Not applicable · MediBeacon Inc. · MediBeacon® Transdermal GFR System for the Evaluation of Kidney Function in Adults With Heart Failure NCT07349797
Not applicable · MiMedx · Post-Marketing Surveillance of Dehydrated Human Amnion/Chorion Membrane (DHACM) in Non-Ischemic Chronic Wounds NCT06236750
Phase 2 · Mirum Pharmaceuticals · A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis NCT05050136
Phase 1 · Monopar Therapeutics · Dose-Escalation of MNPR-101-PCTA-177Lu in Solid Tumors NCT06617169
Phase 1 · Neomorph · Open-Label Phase 1/2 Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell Carcinoma NCT07300241
Phase 2 · Newleos · A Study of NTX-1472 in Social Anxiety Disorder NCT07323784
Not applicable · Noctrix Health, Inc. · Tonic Motor Activation (TOMAC) Therapy in Patients With Restless Legs Syndrome and Dopaminergic Augmentation NCT07397247
Phase 1 · Nurix Therapeutics · A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies NCT05131022
Phase 1 · Nuvalent · A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1) NCT06521554
Phase 2 · OncoVerity · A Study Comparing Venetoclax and Azacitidine Plus Cusatuzumab to Venetoclax and Azacitidine in Newly Diagnosed AML Ineligible for Intensive Therapy NCT06384261
Phase 1 · Oruka Therapeutics · ORKA-002-211 A Phase I Study to Evaluate ORKA-002 in Healthy Volunteers Following A Single Dose NCT06944379
Phase 3 · Praxis Precision Medicines · Randomized Clinical Trial Evaluating the Efficacy and Safety of Vormatrigine in Adults With Focal Seizures NCT07505004
Not applicable · Presidio Medical · Ultra Low Frequency Neuromodulation for Nociceptive Chronic Low Back Pain NCT06763653
Phase 1 · Prolium Bioscience · A Phase 1/2 Study of PRO-203 in Healthy Volunteers and Participants With Systemic Sclerosis. NCT07641634
Not applicable · RapidPulse · The Pivotal Study of RapidPulseTM Aspiration System NCT06029491
Early phase 1 · RayzeBio · Imaging Study in Metastatic Clear Cell RCC. NCT07671417
Phase 1 · Sagimet Biosciences · Phase 1 Study to Evaluate the Safety, Tolerability, PK, and PD of TVB-3567 in Healthy Participants With or Without Acne NCT06989840
Not applicable · Spiro Medical · PULmonary Stimulation for Asthma Relief NCT07709754
Phase 1 · Tortugas Neuroscience · A Study to Test a Single Dose of a New Tablet Formulation of TRTL-729 NCT07811063
Phase 3 · Ultragenyx Pharmaceutical · Setrusumab in Pediatric Japanese Subjects With Osteogenesis Imperfecta NCT06636071
Phase 3 · Vantive · Safety Evaluation of Prismocitrate 18 in Patients Receiving CRRT NCT05399537
Phase 3 · VaxCyte · Safety, Tolerability, and Immunogenicity of VAX-31 in Adults ≥50 Years With Immunobridging to Adults 18-49 NCT07284654
Phase not stated · Zimmer Biomet · PMCF Study on the Safety and Performance of the Zimmer® Maxera™ Acetabular System in Total Hip Arthroplasty NCT03372278
Phase not stated · Zimmer Biomet · ROSA Knee Intraoperative Planning Flexibility Study NCT05966519
Not applicable · Alpha Tau Medical · Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia NCT04534127
Phase 1 · Incyte · A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation NCT06179160
Not applicable · RefleXion Medical · SCINTIX [BgRT} Using RMRS in Solid and Soft Tissue Tumors NCT06634706
Phase not stated · Vivex Biologics · VIA Disc NP Registry 3.0 NCT06345690
Phase 1 · Quanta Therapeutics · QTX3544 in Patients With Advanced Solid Tumors With KRAS G12V Mutations NCT06715124
Not applicable · Shape Memory Medical · False Lumen Treatment for Prevention of Aortic Growth Using Shape Memory Polymer - First-in-Human Study (FLAGSHIP_FRA) NCT06740721
Phase 1/Phase 2 · Incyte · A Ph1b/2 Study of Axatilimab Monotherapy in Chinese Participants With Recurrent or Refractory cGVHD NCT06843408
Phase 1 · IDEAYA Biosciences · Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion NCT04794699
Phase 3 · Ocular Therapeutix · Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Axitinib Implant) in Subjects With Neovascular Age- Related Macular Degeneration NCT06495918
Phase 4 · Moderna · A Study to Investigate the Immunogenicity and Safety of mRNA COVID-19 Variant-containing Formulations NCT07863635
Phase 1 · Amgen · Comparing the Extent to Which Romosozumab (AMG 785) is Made Available in the Body When Administered as a Single SC Injection or as 2 SC Injections NCT07811999
Phase 1 · Circle Pharma · Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies NCT06577987
Phase 1/Phase 2 · Azitra Inc. · A Study to Evaluate Topical ATR04-484 for EGFRi-Associated Dermal Toxicity NCT06830863
Phase 1 · Biora Therapeutics · An Early Feasibility Study of the BioJet™ Oral Biotherapeutic Delivery System for Administration of Therapeutic Agents in Healthy Participants NCT07849153
Phase 2/Phase 3 · IDEAYA Biosciences · IDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal Melanoma NCT05987332
Phase 2 · XBiotech · Natrunix in Combination With Methotrexate for Rheumatoid Arthritis Treatment NCT06590090
Phase 1 · Corbus Pharmaceuticals · A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors NCT06265727
Phase 1 · SpringWorks Therapeutics · SW-682 in Advanced Solid Tumors NCT06251310
Phase 1/Phase 2 · Creative Medical Technology Holdings · Safety, Tolerability, and Effectiveness of Intramuscular Injection of CELZ-201-DDT for the Treatment of Chronic Lower Back Pain NCT06053242
Phase not stated · Novo Nordisk A/S · A Research Study to See How Insulin Icodec Helps People With Type 1 Diabetes Control Their Blood Sugar NCT07160816
Phase 2 · Turn Therapeutics · A Double-Blind, Randomized, Vehicle-Controlled Phase 2 Study to Assess the Efficacy and Safety of GX-03 in Adult Subjects With Moderate to Severe Atopic Dermatitis (Eczema) NCT07355075
Phase 3 · Amgen · Evaluation of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight NCT06858839
Phase 1 · ADARx Pharmaceuticals · Phase 1 Study of ADX-626 in Healthy Participants NCT07081503
Phase 3 · Lupin · An Open-Label, Randomized, Cross-Over Study to Investigate the Efficacy and Safety of Mexiletine PR Compared to Mexiletine IR NCT07097701
Phase 1 · ViiV Healthcare · A Study to Investigate the Use of VH3810109 With or Without Fostemsavir (FTR) to Reduce the Size and Activity of the Viral Reservoir in People Living With HIV NCT07053384
Phase 3 · Novo Nordisk A/S · A Research Study to See How a Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine, Both in Combination With Insulin Aspart, in Adults With Type 1 Diabe NCT07076199
Phase 3 · Vertex Pharmaceuticals Incorporated · Evaluation of the Long-term Safety and Effectiveness of Suzetrigine (SUZ) in Participants With Painful Diabetic Peripheral Neuropathy (DPN) NCT06696443
Phase not stated · Swedish Orphan Biovitrum · Pacritinib Effectiveness in Real-world Settings NCT07774455
Phase not stated · MindRhythm · MindRhythm Detection of Concussion and Recovery Study NCT07190963
Phase 3 · Moderna · A Study of mRNA-1018-H5 Pandemic Influenza Vaccine in Healthy Adults NCT07496450
Phase 3 · Novartis · Study to Assess the Efficacy and Safety of Alpelisib Plus Fulvestrant in Participants With HR-positive (HR+), HER2-negative, Advanced Breast Cancer After Treatment With a CDK4/6 Inhibitor and an Aroma NCT05038735
Phase 2 · Dynavax Technologies Corporation · Immunogenicity, Safety, and Tolerability of rF1V-1018 Vaccine in Adults 18 to 55 Years of Age NCT07207408
Phase 1/Phase 2 · IDEAYA Biosciences · Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions NCT03947385
Phase 1 · Orionis Biosciences · ORB-021 In Patients With Advanced Solid Tumors NCT06607939
Phase 1 · Elixirgen Therapeutics · Rollover Study From EXG-US-01 NCT05868499
Phase not stated · GentiBio, Inc · HLA Demographics Study in Adults With Type 1 Diabetes NCT06860516
Phase not stated · Globus Medical · A Retrospective Review: Outcomes of the REFLECT™ System for Idiopathic Scoliosis NCT07589023
Not applicable · TransMedics · Enhancing Heart Allograft Function With the OCS Heart System Trial NCT07145515
Phase 4 · Vertex Pharmaceuticals Incorporated · Evaluation of Pain Treatment After Total Knee Arthroplasty NCT07538570
Not applicable · Adagio Medical · Cryoablation for Monomorphic Ventricular Tachycardia NCT05675865
Phase 1 · Bambusa Therapeutics · A Study of BBT002 in Healthy Volunteers (HVs) and in Adult Patients With Chronic Obstructive Pulmonary Disease (COPD) or Chronic Rhiosininusitis With Nasal Polyps (CRSwNP) NCT06944925
Not applicable · Bausch + Lomb · A Study to Evaluate the Safety and Efficacy of the Bausch + Lomb Myopia Control Lens for the Correction of Myopic Ametropia and Slowing the Progression of Myopia in Children NCT06305663
Not applicable · Bayer AG · A Study to Understand How Cardiac Surgery-associated Acute Kidney Injury Develops in Participants Who Undergo Heart Surgery With the Use of Heart-lung Machine NCT06772025
Phase 1/Phase 2 · Creative Medical Technology Holdings · Safety and Efficacy of CELZ-201 in Patients With Recent Onset Type 1 Diabetes NCT05626712
Phase 2 · Daiichi Sankyo · Long-term, Extension Study of DS-5141b in Patients With Duchenne Muscular Dystrophy NCT04433234
Phase 1 · Exelixis · Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors NCT05176483
Not applicable · ExThera Medical · Safety & Effectiveness Evaluation of Seraph 100 in Treatment of Pts With COVID-19 NCT04547257
Not applicable · Innovative Cardiovascular Solutions · Evaluation of Safety and Effectiveness of the EMBLOK EPS Compared With No Cerebral Embolic Protection During TAVR NCT07129421
Phase 2 · Quoin Pharmaceuticals · Phase 2/3 Clinical Study of QRX003 Lotion in Subjects With Netherton Syndrome NCT07538583
Phase 1 · Serina Therapeutics · SAD Study in Patients With Parkinson's Disease and Motor Fluctuations NCT07422675
Not applicable · Shockwave Medical · Investigational Study of SWM-831 to Treat Moderate and Severely Calcified Femoropopliteal Arteries NCT06938854
Phase 1 · Sparian Biosciences, Inc · Phase 1 Study of SBS-147 in Healthy Adults NCT07335913
Not applicable · Vantive · A Study of the Efficacy and Safety of Extracorporeal Carbon Dioxide Removal Using PrismaLung+ NCT07326215
Phase 4 · Viatris (2) · Abuse Potential of Gabapentin Taken Orally Concomitantly With Oxycodone Hydrochloride in Healthy, Non-Drug-Dependent, Recreational Opioid Users NCT07813026

Feb 2027 (estimated) · 86 trials

Phase not stated · AccurKardia · ECG-based AI Screening for Cases of Undiagnosed Moderate-to-Severe Aortic Stenosis in the Primary Care Setting NCT07827105
Phase 1 · Acrotech Biopharma · Study to Evaluate the Pharmacokinetics and Safety of Pralatrexate in Patients With Advanced Solid Tumor or Hematological Malignancy and Either Normal Hepatic Function or Mild, Moderate, or Severe Hepa NCT07036133
Not applicable · Activ Surgical · A Prospective Study Assessing ActivSight Imaging for Intraoperative Perfusion Evaluation in Left-Sided Colectomy NCT07453797
Not applicable · Alpha Tau Medical · Alpha Radiation Emitters Device (DaRT) for the Treatment of Liver Metastases NCT05829291
Not applicable · Alpha Tau Medical · Alpha Radiation Emitters Device (DaRT) for the Treatment of Recurrent Lung Cancer NCT05632913
Phase 1 · Amylyx Pharmaceuticals · AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis NCT06665165
Phase 1/Phase 2 · Arrowhead Pharmaceuticals · A First-In-Human Study of ARO-ALK7 in Adults With Obesity With and Without Type 2 Diabetes Mellitus NCT06937203
Phase 2 · Bausch + Lomb · BL1107 Response and Intensity Guided Dosing for Hyperemia Resolution Trial NCT07778888
Phase 2 · Bausch + Lomb · A Study to Evaluate the Use of Topical Ocular BL1332 for the Management of Postoperative Ocular Pain Following Photorefractive Keratectomy NCT07412496
Phase 1/Phase 2 · Bond Biosciences · A Study to Evaluate BBI-001 in Healthy Volunteers and in Patients With Hereditary Hemochromatosis NCT07371793
Phase 2 · Candel Therapeutics, Inc. · A Biomarker Study in Men With Localized Prostate Cancer Treated With Aglatimagene Besadenovec NCT07332000
Phase 3 · Celltrion · A Study to Compare Effects and Safety of CT-P51 and Keytruda in Patients With Previously Untreated Metastatic Lung Cancer NCT06939595
Phase 3 · Celltrion · A Study to Compare Efficacy, Pharmacokinetics, Pharmacodynamics and Safety of CT-P53 and Ocrevus in Patients With Relapsing-remitting Multiple Sclerosis NCT05906992
Phase not stated · Cofactor Genomics, Inc. · A Multicenter Cancer Biospecimen Collection Study NCT04510129
Phase 1/Phase 2 · Day One Biopharmaceuticals · A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors NCT05377996
Phase 1 · Denali Therapeutics · A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL628 in Participants With Early Alzheimer's Disease NCT07328451
Phase 2 · Disc Medicine · A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV) NCT06985147
Not applicable · Edwards Lifesciences · Early Feasibility Study of the Edwards APTURE Transcatheter Shunt System NCT07858799
Phase 1 · Formation Bio · A Phase 1 Study of BLKR201 in Healthy Adult Participants NCT07501039
Phase 1 · Forte Biosciences · A Study Testing the Safety and Effects of FB102 in Healthy Volunteers NCT07623057
Phase 2 · Genelux · Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's Choice of Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL Cancer NCT06463665
Phase 1 · Geron · A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of Imetelstat in Combination With Ruxolitinib in Participants With Myelofibrosis NCT05371964
Phase 1 · Gilead · Study of GS-4571 in Healthy Participants, Nondiabetic Obese Participants, and Nonobese Participants With Type 2 Diabetes Mellitus (T2DM) NCT06562907
Not applicable · GT Metabolic Solutions · Magnet System Gastric Outlet Obstruction Study NCT07609511
Phase not stated · Jazz Pharmaceuticals · Epidyolex® in Lennox Gastaut, Dravet Syndrome and Tuberous Sclerosis Complex: an Observational Study in ITALY NCT05485831
Phase 1 · Kali Therapeutics · A First-in-human Study of KT501 Administered Subcutaneously to Patients With Rheumatoid Arthritis (RA). NCT07234773
Phase 3 · Kallyope · A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine NCT07645924
Phase 3 · Kodiak Sciences · A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PINNACLE NCT06996080
Phase 1/Phase 2 · Krystal Biotech · A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs NCT06228326
Phase 2 · Liquidia · A Study of LIQ861 (Inhaled Treprostinil) in Adults With Systemic Sclerosis Who Have Symptomatic Raynaud's Phenomenon Attacks NCT07748000
Phase 1 · Memgen · MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors NCT05076760
Not applicable · Natera · A Comparative Effectiveness Study in Heart Transplant Patients of Rejection Surveillance With Cell-free DNA Versus Endomyocardial Biopsy NCT06414603
Phase 3 · Otsuka · A Phase 3 Trial of OPA-15406 Foam in Children and Infants With Atopic Dermatitis NCT07184645
Phase not stated · Ray Therapeutics · Development and Evaluation of Functional Visual Field and Navigation Endpoints in Moderate to Profound Inherited Retinal Disease (DEFINE-IRD) NCT07502664
Phase 1 · RayzeBio · Study of RYZ401 in Subjects With Solid Tumors Expressing SSTRs. NCT07165132
Phase 1/Phase 2 · RIGImmune · RIG 101 Trial in Healthy Adults and Adults With Asthma NCT07488897
Phase 2 · Rivus Pharmaceuticals · A Trial to Investigate Safety, Exposure, and Efficacy of HU6 Compared With Placebo in Adult Participants With Metabolic Dysfunction-associated Steatohepatitis (MASH) NCT07491458
Phase 2 · Sanaria Inc. · Field Trial of PfSPZ-LARC2 Vaccine in Burkinabe Adults NCT07385287
Not applicable · SeaStar Medical · Feasibility of the SCD in Cardiorenal Syndrome Patients Awaiting LVAD NCT03836482
Phase 1 · Septerna · A Study to Evaluate Single and Multiple Doses of SEP-479 in Healthy Adult Participants NCT07433179
Phase 3 · SK Life Science · Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults NCT05219617
Phase 1/Phase 2 · SparingVision · Promising ROd-cone DYstrophy Gene therapY NCT05748873
Phase 1 · Syndax Pharmaceuticals · A Study of Revumenib in Combination With Intensive Chemotherapy in Participants With Acute Myeloid Leukemias NCT06226571
Phase 2 · TearSolutions · A Multicenter, Randomized, Vehicle-Controlled, Double-Masked to Open-Label Study to Evaluate the Safety and Efficacy of Lacripep in Subjects With Neurotrophic Keratitis NCT07568730
Phase 1 · Xencor · Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma NCT05433142
Not applicable · Brixton Biosciences, Inc. · INJECTABLE COLD ENERGY THERAPY FOR THE MANAGEMENT OF CHRONIC PAIN ASSOCIATED WITH OSTEOARTHRITIS OF THE KNEE NCT06700109
Phase not stated · Nihon Kohden · Hypoxia and Hemodilution Testing in Healthy Adult Volunteers NCT07503171
Not applicable · Sonavex · Maturation of Arteriovenous Fistula With Automated Sonography Assessments Trial NCT06190717
Phase 1/Phase 2 · Tvardi Therapeutics · A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma NCT05440708
Phase 1 · Biogen · A Study to Learn More About the Safety of BIIB145 and How it is Processed in the Body of Healthy Adult Participants NCT07225517
Phase 2 · CellVax Therapeutics · FK-PC101 as Adjuvant Therapy for Men With High-Risk Prostate Cancer NCT06636682
Phase 1 · Nuvation Bio Inc. · Study on the Effect of Famotidine on Pharmacokinetics of Taletrectinib NCT07742384
Phase 1 · Vertex Pharmaceuticals Incorporated · A Phase 1/2 Study of VX-670 in Adult Participants With Myotonic Dystrophy 1 (DM1) NCT06185764
Phase not stated · Biogen · Observational, Postmarketing Surveillance Study of Spinraza Injection (Nusinersen Sodium) NCT04317794
Phase not stated · Smith and Nephew · A Post Approval Multicenter 10 Year Follow-up Observational Trial of Marketed Product - MP01 vs. Surgical Standard of Care (SSOC) Used for the Treatment of Joint Surface Lesions of the Knee NCT06916728
Not applicable · Innoblative Designs, Inc. · Feasibility Study for the SIRA-1000, SIRA® RFA Electrosurgical Device as an Adjunct to Breast Conserving Surgery NCT07206121
Phase 1 · Insmed · A Study to Evaluate the Pharmacokinetics (PK) and Safety of a Single Dose of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Normal Hepatic Function and Participants With Hepatic I NCT07643155
Phase 2 · Abcentra · Focused Orticumab Research for Treating Inflammation in Coronary Arteries NCT06927739
Phase 1 · Merck & Co., Inc. · A Clinical Trial of MK-6916 With Midazolam and Rosuvastatin in Healthy Participants (MK-6916-012) NCT07862621
Phase 1 · Terrestrial Bio · Semaglutide Delivered Epi-Intradermally by Microarray Patch (VX-201) Versus Subcutaneous Administration in Healthy Overweight and Obese Participants NCT07673900
Phase 2 · Sanofi · A Study to Investigate the Efficacy and Safety of Rilzabrutinib in Adult Participants With Graves' Disease NCT06984627
Phase not stated · Daiichi Sankyo · Clinical Effectiveness and Safety of Trastuzumab Deruxtecan (T-DXd) in Chinese Patients With HER2m NSCLC (RERUN) NCT06809764
Phase 3 · Ocugen · A Phase 3 Study Of OCU400 Gene Therapy for the Treatment Of Retinitis Pigmentosa NCT06388200
Phase 1/Phase 2 · Evopoint Biosciences · A Study of PARG Inhibitor XNW29016 in Patients With Advanced Solid Tumors Who Failed Standard Treatment NCT06987500
Phase not stated · Vesalio · Registry on NeVa VS for CerebraL VAsospasm ManagemenT in Post SAH PatiEnts NCT06893588
Phase 3 · Moderna · A Study to Investigate the Safety and Efficacy of mRNA-1403 in Participants ≥18 Years of Age for the Prevention of Acute Gastroenteritis NCT06592794
Not applicable · Shape Memory Medical · False Lumen Treatment for Prevention of Aortic Growth Using Shape Memory Polymer - First-in-Human Study NCT06550986
Phase 2 · Takeda · A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease NCT06233461
Phase 1 · Bayer AG · Evaluation of Possible Ways the Body May Process Two Different Forms of Elinzanetant in Healthy Study Participants NCT07762287
Not applicable · ECM Therapeutics · Study Evaluating the Safety and Efficacy of an ECM Hydrogel for the Treatment of Anorectal Fistulas NCT07035925
Phase 3 · Ardelyx · A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults NCT07382167
Phase 2 · NS Pharma, Inc. · NS-089/NCNP-02-201 in Boys With Duchenne Muscular Dystrophy (DMD) NCT05996003
Phase 1 · Jazz Pharmaceuticals · A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JZP269 in Healthy Male and Female Participants NCT07813663
Phase 1/Phase 2 · Aulos Bioscience · Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer NCT05267626
Phase 1 · Bambusa Therapeutics · A Study of BBT001 in Healthy Volunteers (HVs) and in Adult Patients With Atopic Dermatitis (AD) NCT06808477
Not applicable · Boomerang Medical · BOOM-IBD2 Pivotal Clinical Trial NCT06571669
Phase 2 · Forte Biosciences · Randomized, Double Blind, Placebo-controlled Phase 2 Study in Adults With Celiac Disease NCT06982963
Phase not stated · Ipsen · CARegiver BURden, Effectiveness and Other Health Care Measures on Functional Disability, in Patients Treated With Abobotulinumtoxin A for Upper Limb Spasticity NCT06245772
Phase 1 · Macro Biologics · A Study of Amicidin-β Topical Solution for Patients With Surgical or Traumatic Wound Infections NCT07379684
Phase 1/Phase 2 · NeOnc Technologies · Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis NCT06047379
Phase 4 · On Target Laboratories · CYTALUX Dose Extension Study NCT07469202
Phase 2 · R1 Therapeutics · A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia NCT06712654
Not applicable · Saluda Medical · Clinical Utility of Neurophysiological Measurements of ECAP-controlled Closed-loop SCS to Guide Treatment of Chronic Pain NCT06229470
Phase 1 · SpyGlass Pharma · Evaluation of the Safety, Efficacy, Dose Response of the Bimatoprost Drug Ring System (BIM-DRS) in Pseudophakic Patients Diagnosed With Open Angle Glaucoma or Ocular Hypertension NCT07641296
Phase 1 · SystImmune · Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of BL-M05D1 in Subjects With Solid Tumors NCT07021066
Phase not stated · Wren Laboratories · A Single-arm, Multicenter Prospective Study to Evaluate the Diagnostic Performance of PROSTest in Men With PSA ≥ 3ng/ml Using Biopsy as the Sole Ground Truth NCT07454603

Mar 2027 (estimated) · 123 trials

Not applicable · Aerin Medical · Measuring Nasal Airway Changes After VivAer Treatment Using AI Analysis NCT07574918
Phase 2 · Aligos Therapeutics · A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME) NCT06963710
Phase 2 · Allarity Therapeutics · Investigation of the Anti-tumor Effect of 2X-121 in Patients With Recurrent, Advanced Ovarian Cancer NCT03878849
Phase 2 · AllRock Bio · A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY) NCT07175038
Phase 3 · Amicus Therapeutics · ZIP Study-OL Study of Safety, PK, Efficacy, PD, Immunogenicity of ATB200/AT2221 in Pediatrics Aged 0 to < 18 y.o. w/LOPD NCT03911505
Phase 1 · Aura Biosciences · A Phase 1, Open-label Trial of Belzupacap Sarotalocan (AU-011) in Bladder Cancer NCT05483868
Phase 2 · Azevan Pharmaceuticals Inc · Inhibition of Aggressive Behavior in Participants With Fragile X Syndrome NCT07328529
Phase 1 · Bio-Path Holdings · A Clinical Trial of BP1002 in Patients With Refractory/Relapsed Acute Myeloid Leukemia (AML) NCT05190471
Phase 2 · BioMarin Pharmaceutical · A Study of Vosoritide in Children With Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatment NCT06668805
Phase 2 · Biomea Fusion · Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Who Are Not Achieving Glycemic Targets NCT07502495
Phase 3 · BlueRock Therapeutics · A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease NCT06944522
Phase 1 · Celldex Therapeutics · A Study of CDX-622 in Participants With Mild to Moderate Asthma NCT07330778
Phase not stated · Celltrion · A Study to Evaluate the Safety of Remsima® SC in the Treatment of RA, AS, PsA and Ps NCT05866614
Phase 1/Phase 2 · Cogent Biosciences, Inc. · A Study of an FGFR2/3 Inhibitor (CGT4859) in Patients With Cholangiocarcinoma and Other Advanced Solid Tumors NCT06777316
Phase 1/Phase 2 · Compugen · A Clinical Trial to Evaluate the Safety and Efficacy of COM701 in Relapsed Platinum Sensitive Ovarian Cancer NCT06888921
Phase 1/Phase 2 · Deciphera Pharmaceuticals, LLC · A Study of Inlexisertib (DCC-3116) in Combination With Anticancer Therapies in Participants With Advanced Malignancies NCT05957367
Phase 2 · Denali Therapeutics · Safety and Pharmacodynamic Effects of BIIB122 in Participants With LRRK2-Associated Parkinson's Disease (LRRK2-PD) NCT06602193
Not applicable · Diality · Moda-flx Hemodialysis System™ Under Professional Care Settings by Trained Individuals and At Home by Participants NCT06613568
Phase 2 · Edgewise Therapeutics · Phase 2 Study of EDG-5506 in Children and Adolescents With Duchenne Muscular Dystrophy Previously Treated With Gene Therapy NCT06100887
Phase 2 · Eli Lilly · A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes NCT07215559
Phase 2 · Eli Lilly · A Study of Solbinsiran (LY3561774) in Participants With Severe Hypertriglyceridemia NCT07269210
Phase 1 · Evergreen Therapeutics · Pharmacokinetic Study to Evaluate Safety and Tolerability of EG-101 in Healthy Female Volunteers as a Safety Lead-In for Dosing in Pregnant Women With Severe Pre-eclampsia NCT07327255
Phase 2 · Evergreen Therapeutics · Safety Lead-In Study of a Repurposed Drug Added to the Combination of Len Plus Pem NCT05106127
Phase 2 · Genmab · A Study to Evaluate Adverse Events of Subcutaneous (SC) Epcoritamab Administered in the Outpatient Setting in Adult Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma and Classic F NCT05451810
Phase 2 · Gilead · Study of Sacituzumab Govitecan Combinations in First-line Treatment of Participants With Advanced or Metastatic Non-Small-Cell Lung Cancer (NSCLC) NCT05186974
Phase 2 · Gilead · Study of Novel Treatment Combination Therapies in Participants With Head and Neck Squamous Cell Carcinoma Regardless of PD-L1 Expression Status; Substudy-01 NCT06727565
Phase 1 · Gilead · Study of GS-0151 in Participants With Rheumatoid Arthritis NCT06902519
Phase not stated · Glaukos · iDose TR Administration in an Office-Based Surgery Setting NCT07816692
Phase 3 · Grace Science · Safety and Efficacy of GS-100 Gene Therapy in Patients With NGLY1 Deficiency NCT06199531
Not applicable · GT Metabolic Solutions · Creation of Compression Anastomosis Using the GT Metabolic Magnet System NCT07431723
Phase not stated · GT Metabolic Solutions · MagDI U.S. Registry NCT06928545
Phase 1 · HAYA Therapeutics · A Phase 1, Multiple Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of HTX-001 NCT07867288
Phase 2 · ImmunityBio · A Study to Examine Anktiva for the Treatment of COVID-19. NCT07123727
Phase 1 · Kumquat Biosciences · A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Hematologic Malignancies NCT06645886
Phase 1 · Leal Therapeutics · A Study of LTX-001 In Adult Participants With Acute Exacerbation of Schizophrenia NCT07734493
Phase 3 · Madrigal Pharmaceuticals · A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE) NCT04951219
Phase 2 · MannKind · INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes NCT07224321
Phase 1 · Myosin Therapeutics Inc. · A Phase 1/2 Study of Safety and Tolerability of MT-125 With Chemoradiation in Patients With Newly Diagnosed MGMT Methylated Glioblastoma NCT07604285
Phase 1 · Newleos · Study of NTX-2001 on Alcohol Consumption in Alcohol Use Disorder NCT07520292
Phase 1/Phase 2 · Nuvation Bio Inc. · Safety and Efficacy Study of NUV-1511 in Adult Patients With Advanced Solid Tumors NCT06334432
Phase 1 · Nuvectis Pharma · A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers NCT05873686
Phase 1/Phase 2 · Ocugen · Study to Assess the Safety and Efficacy of OCU400 for Retinitis Pigmentosa and Leber Congenital Amaurosis NCT05203939
Phase 3 · Ocular Therapeutix · A Study to Evaluate the Efficacy and Safety of OTX-TKI (Axitinib Implant) in Participants With Non-Proliferative Diabetic Retinopathy NCT07235085
Phase 2 · PepGen Inc · A Clinical Study of PGN-EDODM1 in People With Myotonic Dystrophy Type 1 NCT06667453
Phase 3 · Quetzal Therapeutics · Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia NCT07504458
Not applicable · Reprise Biomedical · Miro3D Wound Matrix for Treatment of Diabetic Foot Ulcers NCT07632001
Phase 2 · Retension Pharmaceuticals · A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension NCT07142356
Phase 2 · Seaport Therapeutics · A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study) NCT07065240
Phase 1 · Senhwa Biosciences · Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation NCT04890613
Not applicable · ShiraTronics · A PIVOTAL STUDY EVALUATING SAFETY AND EFFICACY OF THE SHIRATRONICS MIGRAINE THERAPY SYSTEM NCT06167655
Phase 3 · Stoke Therapeutics · A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome NCT06872125
Phase 3 · Swedish Orphan Biovitrum · Study to Provide Continued Access to Treatment for Patients Completing a Previous Trial With Efanesoctocog Alfa NCT06716814
Phase 4 · Travere Therapeutics · Sparsentan in Posttransplant Immunoglobulin A Nephropathy or Focal Segmental Glomerulosclerosis NCT07219121
Phase not stated · United Therapeutics · ADAPT - A Patient Registry of the Real-world Use of Orenitram® NCT03045029
Not applicable · Valencia Technologies · A Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE) NCT05685433
Phase 1/Phase 2 · Vanda Pharmaceuticals · Treatment of Charcot-Marie-Tooth Disease, Axonal, Type 2S (CMT2S) in an Individual Patient NCT07223632
Phase 3 · VaxCyte · A Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of VAX-31 With Influenza Vaccine in Adults ≥ 50 Years of Age NCT07365826
Phase 3 · VaxCyte · Safety, Tolerability, and Immunogenicity of VAX-31 in Adults ≥50 Years With Prior Pneumococcal Vaccination NCT07425392
Phase 2 · Vima Therapeutics · A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia NCT07304089
Phase 2 · Walden Biosciences · Study of WAL0921 in Patients With Glomerular Kidney Diseases NCT06466135
Phase 1 · Xentria · A Study to Investigate the Pharmacokinetics and Safety of KM04 Compared to United States (US)-Gonal-f Revised Formulation Female (RFF) Redi-ject and European Union (EU)-Gonal-f in Healthy Adult Female NCT07794683
Phase not stated · Zimmer Biomet · MDR - PMCF Study for RingLoc Bipolar Acetabular Cup and Endo II Femoral Heads NCT05199870
Phase 3 · Novo Nordisk A/S · A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-term NCT07011667
Phase not stated · Takeda · A Study to Better Understand the Diagnosis and Treatment of Polycythaemia Vera NCT07868081
Phase 3 · Zero Point Five Therapeutics · Phase 3, Multi-center, Prospective, Randomized, Double-blind, Placebo- Controlled Study to Evaluate the Effectiveness and Safety of ZP5-9676 for the Treatment of Soil Transmitted Helminthiasis (STH) NCT06128447
Phase 2 · Boehringer Ingelheim · A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy NCT06321302
Phase 1 · Vertex Pharmaceuticals Incorporated · A Phase 1, First-in-human Study of VX-433 NCT07584434
Phase 1 · Angiex, Inc. · A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors NCT06440005
Phase 2 · Moderna · A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Allogenic Hematopoietic Cell Transplantation (HCT) Participants. NCT05683457
Phase 1 · Mirador Therapeutics · A First-in-Human Single and Multiple Ascending Dose Study of MT-251 NCT07423299
Phase 1 · ViiV Healthcare · A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Cabotegravir Ultra Long-acting (CAB ULA) Following Switch From Cabotegravir Long-acting (CAB LA) in Healthy Adults NCT06786520
Phase 1 · Forte Biosciences · A Study to Evaluate the Safety and Efficacy of FB102 in Patients With Severe to Very Severe Alopecia Areata. NCT07205159
Phase 1 · Vertex Pharmaceuticals Incorporated · Effects of VX-407 on the Pharmacokinetics of Combined Oral Contraceptives NCT07792408
Phase 2 · Travere Therapeutics · Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases NCT05003986
Phase 1/Phase 2 · Vertex Pharmaceuticals Incorporated · A Safety, Tolerability, and Efficacy Study of VX-264 in Participants With Type 1 Diabetes NCT05791201
Phase 1 · Amgen · Evaluation of Xaluritamig in High-Risk, Biochemically Recurrent, Non-metastatic Castrate-sensitive Prostate Cancer NCT06555796
Phase 3 · Rhythm Pharmaceuticals · A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756) NCT06760546
Phase not stated · Pharmanest · Artificial Intelligence For Outcomes Research in Crohn's Disease: Digital Pathology Assessment of Fibrosis and Association With Patient History and Clinical Outcomes NCT07795476
Phase 1 · Insmed · A Study to Assess the Safety, Tolerability and Pharmacokinetics (PK) of INS1033 in Healthy Participants NCT07765706
Phase 1 · Amgen · Comparing the Extent to Which Two Maridebart Cafraglutide Drug Products Are Made Available in the Body After a Single Subcutaneous Dose NCT07832799
Phase 1/Phase 2 · Boehringer Ingelheim · A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated NCT07553429
Not applicable · Surgenex · Study Assessing Complete Wound Healing by Comparing Surgenex® PelloGraft in Treating DFU and SanoGraft® in Treating VLU to SOC NCT06515093
Phase 1 · Bristol-Myers Squibb · A Study of Navlimetostat (BMS-986504) Drug Interactions and Food Effect in Healthy Participants NCT07800897
Phase 2 · OrthoTrophix · 53-Week Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 With Mild to Severe Tibio-Femoral Osteoarthritis of the Knee NCT06865079
Phase 2 · Vertex Pharmaceuticals Incorporated · Evaluation of Efficacy and Safety of VX-993 for Pain Associated With Diabetic Peripheral Neuropathy NCT06619860
Phase 2 · Ipsen · A Study of IPN10200 for the Treatment of Cervical Dystonia in Adults NCT06937931
Phase 1 · Incyte · A Study to Evaluate INCB186748 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation NCT06818812
Phase not stated · Biogen · A Long-Term Study of Patient-Reported Changes in Postpartum Depression Symptoms in People Starting Zuranolone NCT07398469
Phase 1 · TORL BioTherapeutics · A Phase 1, First in Human Study of TORL-4-500 in Patients With Advanced Cancer NCT06005740
Phase 1 · Aspen Neuroscience · Phase 1/2a Study of ANPD001 in Parkinson Disease NCT06344026
Phase 1 · Incyte · A Study to Evaluate the Pharmacokinetics and Safety of INCB161734 in Participants With Impaired Renal Function and Participants on Hemodialysis NCT07854249
Phase not stated · InVivoScribe · The Use of Residual De-identified Specimens and/or Samples From Patients for Clinical Research NCT06222164
Phase not stated · Novartis · A Study of Patient Characteristics, Co-Morbidities, and Treatment Patterns in Chronic Myeloid Leukemia Patients in Kuwait NCT07454850
Not applicable · TELA Bio · Ventral or Inguinal Hernia, Robotically Repaired With OviTex Mesh NCT04779918
Phase 1 · TerSera Therapeutics · A Trial to Evaluate Ovarian Suppression Following Subcutaneous ZOLADEX 10.8 mg in Premenopausal Women With Early-stage and Advanced HR+ Breast Cancer NCT07310420
Not applicable · Adagio Medical · Cryoablation for Monomorphic Ventricular Tachycardia (VTS) NCT07650032
Phase 3 · Ascentage Pharma · A Study of Olverembatinib in SDH-deficient GIST. NCT06640361
Phase not stated · Bayer AG · An Observational Study to Collect Data on How Aflibercept (Eylea) Given Using a Paediatric Dosing Device is Used in Preterm Babies With Retinopathy of Prematurity in the United Kingdom (UK) NCT06315556
Phase 1 · Boehringer Ingelheim · DAREONᵀᴹ-8: A Study to Test How Well Different Doses of BI 764532 in Addition to Standard of Care Are Tolerated by People With Advanced Small Cell Lung Cancer NCT06077500
Phase 1 · Boehringer Ingelheim · A Study to Test Different Doses of BI 1701963 Alone and Combined With Trametinib in Patients With Different Types of Advanced Cancer (Solid Tumours With KRAS Mutation) NCT04111458
Phase not stated · Bristol-Myers Squibb · Evaluation of Mavacamten-Based Practice in Chinese Adults With Obstructive Hypertrophic Cardiomyopathy NCT07846059
Not applicable · CardioFocus · Pulmonary Vein Isolation With the Single Shot Endoscopic Ultra-Compliant PFA Balloon for the Treatment of AF NCT06828939
Phase 1/Phase 2 · CellCentric · Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies NCT04068597
Phase 2 · CG Oncology · Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC NCT06567743
Phase 1 · Comanche Biopharma · A Study to Investigate the Safety, Pharmacodynamic and Pharmacokinetic Characteristics of CBP-4888 in Hospitalized Participants With Preterm Preeclampsia and Their Children up to 24 Months NCT07282171
Not applicable · Globus Medical · REFLECT Scoliosis System Post Approval Study NCT06298812
Phase 1 · Incyte · A Study to Evaluate the Pharmacokinetics and Safety of INCB161734 in Participants With Hepatic Impairment NCT07853040
Phase not stated · Ipsen · Observational Real-life Study of Cabozantinib in Monotherapy or in Combination With Nivolumab in Advanced Renal Cell Carcinoma (RCC) NCT04106349
Phase not stated · Lumos Diagnostics · FebriDx® Pediatric Validation Study NCT07211997
Phase 2 · Merakris Therapeutics · MTX-001 for the Treatment of Non-Healing Venous Stasis Ulcers NCT04647240
Phase 1 · Modulation Therapeutics, Inc. · Targeted Alpha Particle Radiotherapy for Metastatic Uveal Melanoma NCT05496686
Phase 3 · Neuraptive Therapeutics · This Study Will Evaluate the Effectiveness of NTX-001, a Surgical Nerve Repair Product When Used in People With Upper Extremity Nerve Lacerations. NCT06616025
Phase 1 · Neutrolis, Inc. · Phase 1a/b Tolerability of NTR-1011 in Healthy Adults and Adult Patients With SLE and RA NCT07237659
Phase not stated · Pulmonx · Zephyr Valve Japan Post-Marketing Surveillance NCT06332885
Phase 1 · REVOLUTION Medicines · Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors NCT05462717
Phase not stated · Spark Biomedical, Inc. · Sensing Physiological Symptoms of Opioid Withdrawal and Cravings in Patients With Opioid Use Disorder NCT06487533
Phase 1/Phase 2 · Tango Therapeutics, Inc. · Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss NCT06810544
Phase 2 · Teclison · TATE and Pembrolizumab (MK3475) in mCRC and NSCLC NCT04701476
Phase 1 · Therini Bio · A Study Intravitreal THN391 in Diabetic Macular Oedema Secondary to Non-Proliferative Diabetic Retinopathy. NCT06701721
Phase 1 · Therini Bio · A Study to Assess THN391 in Subjects With Alzheimer's Disease NCT06814730
Phase 2/Phase 3 · TuHURA Biosciences · Placebo-Controlled Trial of IFx-Hu2.0 Followed By Pembrolizumab In Checkpoint Inhibitor Naïve Participants With Advanced Or Metastatic Merkel Cell Carcinoma NCT06947928
Phase 2 · Vast Therapeutics · Study on Doses of Inhaled ALX1 in Adults With Bronchiectasis NCT07731919
Phase 2 · VIVUS · A Study of Carmustine With and Without Ethanol in Subjects With Lymphoma NCT06915246

Apr 2027 (estimated) · 83 trials

Not applicable · Alpha Tau Medical · Alpha Radiation Emitters Device (DaRT) for Target Treatments of Malignant Tumors NCT05781555
Not applicable · Alpha Tau Medical · Alpha Radiation Emitters Device (DaRT) for the Treatment of Recurrent Cutaneous Squamous Cell Carcinoma NCT05323253
Phase 1 · Alveus Therapeutics · Study of ALV-100 to Assess Safety, Tolerability, and PK/PD in Overweight/Obese Participants With or Without T2D NCT07399678
Phase 1 · Ankyra Therapeutics · Phase I Study of Tolododekin Alfa (ANK-101) in Advanced Solid Tumors NCT06171750
Phase 1 · Apriligen · Assessing the Safety, Tolerability, and Efficacy of APR-2020 in Pediatric and Adolescent Subjects With RPS19 Deficient Diamond-Blackfan Anemia NCT07476183
Phase 1 · Assembly Biosciences · A Study to Assess the Safety, Tolerability and Pharmacokinetics of ABI-6250 in Participants With Mild Hepatic Impairment Compared With Participants With Normal Hepatic Function NCT07850999
Phase 1 · Auron Therapeutics · Phase 1 Study of AUTX-703 in Relapsed/Refractory AML and MDS NCT06846606
Phase 2 · Cardurion Pharmaceuticals · A Phase 2 Study of CRD-4730 in CPVT NCT06658899
Phase 1 · Climb Bio · A Phase 1b Study of Budoprutug in Systemic Lupus Erythematosus (SLE) NCT07011043
Not applicable · Cochlear · A Pivotal Study to Evaluate the Efficacy and Safety of a Totally Implantable Cochlear Implant (TICI) System in Adults NCT07139327
Phase 3 · Doron Therapeutics · A Study to Evaluate the Efficacy and Safey of PTP-001 (MOTYS™) in Knee Osteoarthritis Patients NCT07219771
Not applicable · Edwards Lifesciences · Early Feasibility Study - Edwards APTURE Transcatheter Shunt System NCT03523416
Phase 1 · Eli Lilly · A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 ) NCT07101328
Not applicable · Envoy Medical · Pivotal Clinical Trial Evaluating the Safety and Efficacy of the Fully Implanted Acclaim Cochlear Implant NCT06699797
Phase 1 · Equillium · A Phase I, Randomized, Double-Blind, Placebo-Controlled Study of EQ504 in Single and Multiple Ascending Doses in Healthy Volunteers NCT07869225
Phase 2 · Glaukos · Placebo-controlled Study to Evaluate the Safety and Efficacy of GLK-221 Ophthalmic Solution in Subjects With Keratoconus NCT07400952
Phase not stated · icometrix · Clinical Impact Through AI-assisted MS Care - A Retrospective Multi-center Observational Study. NCT06280755
Not applicable · Imbed Biosciences · Safety Study of Microlyte DualGuard NCT07695688
Phase not stated · Inari Medical · RevCore for In Stent Thrombosis NCT06394739
Phase 1/Phase 2 · Karyopharm Therapeutics Inc. · Selinexor and Backbone Treatments of Multiple Myeloma Patients NCT02343042
Phase 3 · Kodiak Sciences · A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK NCT06990399
Phase 1 · Kymera Therapeutics, Inc. · A Study to Evaluate Different Oral Formulations of KT-621 NCT07823205
Phase 2 · Kyverna Therapeutics · KYSA-7: A Study of Anti-CD19 CAR T-Cell Therapy, in Subjects With Refractory Primary and Secondary Progressive Multiple Sclerosis NCT06384976
Phase 3 · LeonaBio · Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation NCT05696626
Phase 2/Phase 3 · MediciNova · Evaluation of MN-166 (Ibudilast) for 12 Months Followed by an Open-label Extension for 6 Months in Patients With ALS NCT04057898
Phase not stated · Natera · EXpanding Prenatal Cell Free DNA Screening Across moNogenic Disorders (EXPAND) NCT06808880
Phase 2 · NGM Biopharmaceuticals · An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia. NCT07033026
Phase 1 · Nkarta Therapeutics · A Phase 1/2 Study of NKX019 in Subjects With Autoimmune Disease (Ntrust-1) NCT06557265
Not applicable · Novonesis · Exploring Wellbeing Outcomes in Adolescents Using Bifidobacterium Longum, 1714™: a Prospective Open-Label Real-World Study NCT07752342
Phase 1/Phase 2 · Nura Bio · A Clinical Trial to Evaluate NB-4746 in Participants With Amyotrophic Lateral Sclerosis. NCT07369076
Phase 2 · Pulmotect · PUL-042 Treatment in Patients With Parainfluenza Virus (PIV), Human Metapneumovirus (hMPV) or Respiratory Syncytial Virus (RSV) NCT06665100
Not applicable · Pulse Biosciences, Inc. · CellFX® Nanosecond Pulsed Field Ablation (nsPFA)™ Cardiac Surgery Clamp System to Treat Atrial Fibrillation NCT06959121
Phase 2 · Riboscience · Evaluation of RBS2418 in Combination With Tremelimumab Plus Durvalumab in Participants With Advanced Unresectable Hepatocellular Carcinoma NCT07175441
Phase 1 · Riboscience · Evaluation of RBS2418 in Subjects With Advanced, Metastatic Solid Tumors NCT05270213
Phase 1 · Santa Ana Bio · Phase 1 Study Involving SAB01 and Healthy Participants NCT07815561
Phase not stated · Sinaptica Therapeutics · Precuneus Mapping With Sinaptistim® (an Investigational TMS-EEG System) in Mild to Moderate AD Patients NCT07841808
Phase 2/Phase 3 · Taiho Oncology · Futibatinib in Patients Previously Enrolled in an Antecedent Futibatinib as Monotherapy or Combination Therapy. NCT06506955
Phase 2 · Trellis Bioscience · Study to Evaluate the Efficacy and Safety of TRL1068 for the Treatment of Prosthetic Joint Infection NCT06621251
Phase 4 · Viridian Therapeutics, Inc. · An Open-Label Trial of Veligrotug in Participants With Thyroid Eye Disease Who Previously Responded to Teprotumumab NCT07832136
Phase 3 · vTv Therapeutics · Cadisegliatin as Adjunctive Therapy to Insulin in Participants With Type 1 Diabetes NCT06334133
Not applicable · BioCardia · CardiAMP Heart Failure II Trial for Patients With Ischemic Heart Failure With Reduced Ejection Fraction NCT06258447
Phase not stated · Castle Biosciences · Evaluation of a Non-Invasive Device for Early Detection of Atopic Dermatitis Flares NCT07645820
Phase 3 · Cerium Pharmaceuticals · A Study of SNP-ACTH (1-39) Gel in Patients With Primary Membranous Nephropathy NCT05696613
Not applicable · EBR Systems · A Feasibility Study Implant of the WiSE® CRT System With an Intracardiac Pacemaker to Achieve Totally Leadless CRT NCT06561932
Phase not stated · Eko Devices · Data Collection Using Eko Digital Devices in a Clinical Setting NCT07227376
Phase 1 · NextPoint Therapeutics · NPX372, a B7-H7:CD3 Bispecific Antibody, in Selected Solid Tumor Malignancies NCT07563829
Phase 1 · Nuravax, Inc. · DUVAX: A Phase 1 Alzheimer's Vaccine Study Targeting Amyloid-Beta and Tau NCT07142278
Phase 1/Phase 2 · Parabilis Medicines, Inc. · FOG-001 in Locally Advanced or Metastatic Solid Tumors NCT05919264
Phase 1 · Quanta Therapeutics · QTX3034 in Patients With KRAS G12D Mutation NCT06227377
Not applicable · Shape Memory Medical · False Lumen Treatment for Prevention of Aortic Growth Using Shape Memory Polymer - First-in-Human Study (FLAGSHIP_CHL) NCT07387250
Phase 1 · Trotana Therapeutics · Phase 1 Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TRT-448 in Healthy Adult Subjects NCT07745751
Phase 3 · Vertex Pharmaceuticals Incorporated · Study to Evaluate Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) Long-term Safety and Efficacy in Subjects Without F508del NCT05331183
Phase 3 · Vertex Pharmaceuticals Incorporated · Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy NCT07231419
Phase 2 · Sanofi · A Study to Investigate the Efficacy and Safety of SAR444336 in Adults With Microscopic Colitis in Clinical Remission NCT07156175
Phase 3 · Bayer AG · A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE In NCT05196035
Not applicable · DermaSensor · DermaSensor Postmarket Surveillance Study NCT06666790
Phase 1 · BioMarin Pharmaceutical · A Phase 1/2 Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BMN 351 in Participants With Duchenne Muscular Dystrophy NCT06280209
Phase 1 · QuantX Biosciences · Phase 1 Study of QX-4533 in Healthy Volunteers and Patients With Moderate-to-Severe Atopic Dermatitis NCT07800104
Phase 3 · Takeda · A Study of Dengue Tetravalent Vaccine (TDV) in Adults (Age 45 to 60 and >60 to 79 Years) NCT06579755
Not applicable · Smith and Nephew · Use of the REGENETEN™ Bioinductive Implant System in High Grade Partial-thickness Tears NCT05444465
Phase 3 · Zydus Therapeutics · Open-Label Extension Study of Saroglitazar Magnesium in Participants With Primary Biliary Cholangitis NCT06427395
Phase 3 · Amgen · Comparison Between ABP 692 and Ocrevus® (Ocrelizumab) NCT06700343
Phase 3 · BioNTech US Inc. · A Study of COVID-19 Vaccine(s) in Children and Adults NCT07798648
Phase 1 · Sanofi · Study to Assess the Plasma Concentration of Rilzabrutinib Given as a Tablet to Adult Participants With Severe Renal Impairment Compared to Matched Participants With Normal Renal Function NCT07853131
Phase 1 · Alessa Therapeutics, Inc. · Bicalutamide Implants (Biolen) With Radiation Therapy in Patients With Localized Prostate Cancer NCT04943536
Phase 1 · Pyxis Oncology, Inc · A Study of PYX-201 in Advanced Solid Tumors NCT05720117
Phase 1 · Bayer AG · A Phase I Study of BAY3498264 Given Together With Sotorasib in Participants Who Have Advanced Solid Cancers With Specific Genetic Changes Called KRASG12C Mutation NCT06659341
Phase 1/Phase 2 · Alnylam Pharmaceuticals · A Study to Evaluate ALN-2232 in Participants With Obesity NCT07463846
Phase 2 · Incyte · A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression NCT07023627
Phase not stated · Volta Medical · Clinical and Healthcare Economic OutcoMes From ReAl-worlD Use in Europe of an AI Software During AF Ablation NCT06083012
Phase 3 · Boehringer Ingelheim · A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilast NCT06238622
Phase 1/Phase 2 · Accent Therapeutics · First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, as Monotherapy and in Combination With Anticancer Therapy in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer NCT06799065
Phase 2 · Avidity Biosciences · Ph2 Open-label Study of AOC 1044 in Duchenne Muscular Dystrophy Participants With Mutations Amenable to Exon44 Skipping NCT06244082
Phase 1/Phase 2 · Daiichi Sankyo · Study of Ifinatamab Deruxtecan (DS-7300a, I-DXd) in Participants With Advanced Solid Malignant Tumors NCT04145622
Not applicable · Daré Bioscience · Contraceptive Efficacy Study of Ovaprene NCT06127199
Phase 2 · IDEAYA Biosciences · (Neo)Adjuvant IDE196 (Darovasertib) in Patients With Localized Ocular Melanoma NCT05907954
Phase 3 · Incyte · A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Children (6 to < 12 Years Old) With Nonsegmental Vitiligo NCT06804811
Not applicable · InterVene · RECANA OUS - Recana Thrombectomy Catheter System for Venous Obstruction and Occlusion Study (RECANA-OUS-IRL) NCT07095660
Phase 2 · Mirador Therapeutics · A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease NCT07113522
Phase not stated · NeurOptics · Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy NCT07573150
Phase 1 · Relay Therapeutics, Inc. · First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in NCT05216432
Phase 4 · Rigel Pharmaceuticals · Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies NCT07486713
Phase 1/Phase 2 · Sumitomo Pharma America, Inc. · A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis NCT04176198

May 2027 (estimated) · 100 trials

Phase 3 · Alkermes, Inc. · A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 2 NCT07502443
Phase 3 · Alkermes, Inc. · A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 1 NCT07455383
Phase 2 · Arcus Biosciences · Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer NCT04736173
Phase 1 · Arcus Biosciences · Comparative PK Assessment Study of Casdatifan in Moderate Hepatically Impaired Participants Versus Matched Participants With Normal Hepatic Function NCT07751250
Phase 1 · Ascentage Pharma · APG-2449 Monotherapy or in Combination With PLD in Patients With Platinum-resistant Recurrent OC or Advanced ST NCT06687070
Phase not stated · BlueRock Therapeutics · Continued Evaluation of Patients With Parkinson's Disease Who Previously Received BRT-DA01 NCT05897957
Phase 1/Phase 2 · Bolt Biotherapeutics · A First-in-Human Study Using BDC-4182 as a Single Agent in Advanced Gastric and Gastroesophageal Cancer NCT06921837
Not applicable · Cochlear · Investigation to Evaluate the Safety and Effectiveness of Cochlear Implantation in Children and Adults With Unilateral Hearing Loss/Single-sided Deafness NCT05318417
Not applicable · ConvaTec · IDEAL: Efficacy of Porcine Placental Extracellular Matrix Augmented Plus Standard of Care (SOC) Versus SOC Alone for the Management of Diabetic Foot Ulcers NCT06616844
Phase 3 · Crinetics Pharmaceuticals, Inc. · A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia NCT07144163
Phase 1/Phase 2 · Disc Medicine · Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia NCT05320198
Phase 1 · Dren Bio · A Study of DR-01 in Subjects With Alopecia Areata and Vitiligo NCT06602232
Phase 2 · Eli Lilly · A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide NCT06897475
Phase 2 · Eli Lilly · A Study of LY4005130 in Adult Participants With Non-Segmental Vitiligo NCT07533019
Phase 2 · Eli Lilly · LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis: NCT07186101
Phase 2 · Eli Lilly · A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event NCT07783802
Phase 3 · Eli Lilly · A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes Who Observe Ramadan Fasting NCT07613307
Phase not stated · Endologix · The Long-Term EVAR Assessment and Follow-Up (LEAF) Study for the AFX2 System NCT06990048
Phase 2 · Extend Biosciences Inc. · A Phase 2 Trial Investigating the Safety, Tolerability and Efficacy of EXT608 in Adults With Hypoparathyroidism NCT06988670
Phase 3 · Gameto · Fertilo In Vitro Research Study and Trial NCT06858111
Phase 4 · Glaukos · Travoprost Intraocular Implant + iStent Infinite NCT06066645
Phase 3 · GRIN Therapeutics · Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder NCT07224581
Phase 1 · GRIN Therapeutics · Radiprodil in Participants With Hepatic Impairment NCT07457229
Phase 1 · iBio · A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of IBIO-600 in Overweight or Obese Adults NCT07487376
Phase not stated · Igenomix · Pilot Study of Discarded Blastocysts NCT07429097
Phase 2 · ImmunityBio · A Phase 2, Open-label, Single-arm Study Of Autologous M-CENK Adoptive Cell Therapy And N-803 (IL-15 Superagonist) In Combination With Gemcitabine In Participants With Recurrent Platinum-Resistant High NCT06710288
Phase 2 · Immunovant · A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease NCT07018323
Phase 2 · Kailera Therapeutics · Efficacy and Safety of Ribupatide (KAI-9531) Administered Once Weekly in Participants Living With Obesity Who Do Not Have Diabetes NCT07458269
Phase 4 · Liquidia · A Study of Inhaled Treprostinil (LIQ861) in Adults With Pulmonary Arterial Hypertension Transitioning From Oral Selexipag NCT07759804
Phase 1 · Mediar Therapeutics · Evaluation of MTX-439 in Healthy Adults and Adults With Diabetic Kidney Disease NCT07473323
Phase not stated · Nanoscope Therapeutics · Non-interventional Long Term Follow-up Study of Participants Previously Enrolled in the STARLIGHT Study NCT06048185
Phase not stated · Renata Medical · Minima Stent System Post- Approval Study (PAS) NCT06828770
Phase 2 · Seaport Therapeutics · An Open-Label Extension Study to Evaluate the Safety and Tolerability of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 OLE Study) NCT07161700
Phase 2/Phase 3 · Skyhawk Therapeutics · Study of SKY-0515 for Safety, Efficacy, and Pharmacodynamics in Participants With Huntington's Disease NCT06873334
Phase 1 · Solve Therapeutics · SLV-324 Treatment of Metastatic Solid Tumors NCT07108114
Not applicable · STAAR Surgical · Study of an Implantable Collamer Lens (ICL) NCT07791381
Not applicable · STAAR Surgical · Study of a Phakic Implantable Collamer Lens (ICL) NCT07790965
Phase not stated · Stemline Therapeutics · A Non-interventional Study of Participants With BPDCN Treated With Chemotherapy NCT07785180
Phase 1 · Strand Therapeutics · Phase 1/2 Study of Intratumoral Injection of STX-001 in Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab NCT06249048
Phase 2 · Vaxart · A Study to Evaluate VXA-CoV2-3.3 COVID-19 Vaccine Against Currently Approved/Authorized mRNA COVID-19 Injectable Booster Vaccine in Adults Previously Immunized Against COVID-19 Infection NCT06672055
Phase 3 · Verrica Pharmaceuticals · Cantharidin Application in Patients With Common Warts (Verruca Vulgaris) (COVE-3) NCT07637734
Phase 1 · Viking Therapeutics · A Phase 1 Study of VK2735 in Obese Adults Without Comorbidities NCT07838740
Phase 3 · Vor Biopharma · A Study of Telitacicept for the Treatment of Generalized Myasthenia Gravis (UPSTREAM MG) NCT06456580
Phase 1/Phase 2 · Voyager Therapeutics · VY7523-102: Randomized, Placebo-Controlled, Double-Blind, Multiple Ascending Dose Study in Participants With Early Alzheimer's Disease NCT06874621
Phase 1 · Xencor · Study of XmAb412 in Healthy Participants NCT07713485
Phase 2 · Zura Bio · Tibulizumab Systemic Sclerosis Understanding and Response Evaluation (TibuSURE) NCT06843239
Not applicable · Adagio Medical · VT Cryoablation System Post-Market Clinical Follow-up (PMCF) Study NCT06384599
Phase 2 · Aqualung Therapeutics, Corp. · Study of Safety and Efficacy of ALT-100mAb in Participants With Moderate/Severe ARDS NCT05938036
Phase 3 · IntraBio · Pivotal Study of N-acetyl-L-leucine for CACNA1A NCT07221292
Phase 1 · SciTech Development · Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/ Refractory Small Cell Lung Cancer NCT06922539
Phase 1 · Starlight Therapeutics · A Phase 1b/2a Study to Evaluate the Safety, Pharmacokinetics, and Objective Response of STAR-001 (LP-184) in Combination With Spironolactone in Supratentorial Glioblastoma at First Progression NCT07431216
Phase 4 · Takeda · A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting NCT06581328
Not applicable · Cochlear · An Investigation to Validate Speech Perception Assessment for Adult Cochlear Recipients Using a Mobile Research App NCT06098482
Phase 1 · Novo Nordisk A/S · A Research Study Looking Into How NNC0662-0419 Works With Birth Control Pills and Emptying of the Stomach in Women Not Able to Become Pregnant With Excess Body Weight NCT07525791
Phase 1 · ViiV Healthcare · A Study to Investigate the Safety and PK of VH4770359 in Healthy Participants NCT07525544
Phase 1/Phase 2 · Solid Biosciences Inc. · A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy (INSPIRE DUCHENNE) NCT06138639
Phase 1 · Bayer AG · A Study to Learn About How Safe Nitroglycerin is and How it Affects the Body When Taken Along With Nurandociguat in People With Coronary Artery Disease NCT07431294
Phase 1/Phase 2 · Rhythm Pharmaceuticals · A Study of RM-718 in Healthy Subjects and Patients With MC4R Pathway Impairment NCT06239116
Phase 2 · AusperBio · Study of AHB-137 in Chronic Hepatitis B (CHB) Participants in North America and Europe Regions NCT07654283
Phase 3 · Novo Nordisk A/S · Weight Loss in People Living With Overweight or Obesity and Type 2 Diabetes Following Treatment With Cagrilintide NCT07220759
Phase not stated · Sanofi · French Prospective Observational Study in Patients Eligible for Systemic Therapy for Atopic Dermatitis (AD) NCT06837454
Phase not stated · Exact Sciences · CORRECT Study of Minimal Residual Disease Detection in Colorectal Cancer NCT05210283
Phase 1 · Moderna · A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189 in Healthy Adults 18 to 30 Years of Age NCT07478952
Phase 1 · OncoVerity · Cusatuzumab in Combination With Background Therapy for the Treatment of Participants With Acute Myeloid Leukemia NCT04150887
Phase 1 · SHY Therapeutics · A Study of SHY-ONC6, a Novel Proteasome Inhibitor, in Adults With Advanced or Metastatic Solid Tumors NCT07705334
Phase not stated · Arthrex · Knee Related Subchondral Bone Lesions Treated With IOBP NCT05314608
Phase 3 · Paradigm Therapeutics · Efficacy and Safety Study to Evaluate SD-101 in Epidermolysis Bullosa NCT07482787
Phase 3 · Takeda · A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic Medicines NCT06671483
Phase 3 · Biogen · A Study to Evaluate the Safety, Tolerability, and Efficacy of BIIB017 (Peginterferon Beta-1a) in Pediatric Participants for the Treatment of Relapsing-Remitting Multiple Sclerosis NCT03958877
Phase 1 · Cellenkos · A Clinical Trial of CK0801 (a New Drug) in Patients With Bone Marrow Failure Syndrome (BMF) NCT03773393
Phase 2 · ImmunityBio · Study of Relapsed/ Refractory B-cell Non- Hodgkin Lymphoma NCT07125872
Phase 4 · Biogen · A Study to Learn More About the Long-Term Safety of Tofersen (Qalsody) in Chinese Participants With SOD-1 Amyotrophic Lateral Sclerosis (ALS) NCT07223723
Phase 4 · SK Life Science · Open-label Study of Cenobamate Monotherapy in Adult Subjects With Newly Diagnosed or Recurrent Partial-Onset Epilepsy NCT06453213
Phase 1 · Adjuvia Therapeutics · A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ATI-105 in Healthy Adults NCT07869654
Phase 3 · Taiho Oncology · REZILIENT3 (REsearching ZIpaLertinib In Egfr Non-small Cell Lung Cancer Tumors) NCT05973773
Phase 2 · Alnylam Pharmaceuticals · A Study to Evaluate ALN-4324 on Insulin Sensitivity in Adults With Type 2 Diabetes Mellitus NCT07465224
Phase 2 · SpringWorks Therapeutics · A Study of Nirogacestat in Japanese Adults With Desmoid Tumors/Aggressive Fibromatosis (DT/AF) NCT07170644
Phase 2 · Acrivon Therapeutics · A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma NCT05548296
Phase not stated · Digital Diagnostics · Pivotal Trial for an Automated AI-based System for Detection of Diabetic Retinopathy NCT07844317
Phase 1 · Olema Oncology · Phase 1 Study of OP-3136 in Advanced or Metastatic Solid Tumors NCT06784193
Phase 1 · OnCusp Therapeutics · A Study of CUSP06 in Patients With Platinum-Refractory/Resistant Ovarian Cancer and Other Advanced Solid Tumors NCT06234423
Phase not stated · Agios Pharmaceuticals · Pyruvate Kinase Deficiency Global Longitudinal Registry NCT03481738
Phase 3 · Biogen · A Study to Learn About the Effects of Felzartamab Infusions on Adults With Immunoglobulin A Nephropathy (IgAN) NCT06935357
Phase 2 · Cognition Therapeutics · A Study to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease NCT05531656
Phase 2 · Day One Biopharmaceuticals · A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors NCT04775485
Phase not stated · Eko Devices · Detecting Pulmonary Hypertension With the Eko CORE 500 Digital Stethoscope NCT07136623
Phase not stated · Eko Devices · Development of an Algorithm to Detect Pulmonary Hypertension Using an Electronic Stethoscope NCT05873387
Phase not stated · Eko Devices · Deep Learning Detection of Pulmonary Hypertension and Low Ejection Fraction Via Digital Stethoscope and 3-Lead ECG NCT07087613
Phase 3 · Evopoint Biosciences · Study of XNW28012 in Subjects With Metastatic Pancreatic Cancer Who Received Prior Systemic Therapy NCT07823049
Phase 1/Phase 2 · ExeGi Pharma · Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an IPAA (PROF) NCT05938465
Phase 1 · Exelixis · A Study of XB628 Alone and in Combination With Zanzalintinib in Participants With Recurrent Advanced or Metastatic Solid Tumors NCT06952010
Not applicable · Hyalex Orthopaedics · The Hyalex MTP Study NCT07538141
Not applicable · Hyalex Orthopaedics · The Hyalex First-in-Human Study NCT06344481
Phase 1 · MOMA Therapeutics · Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors NCT06545942
Phase 1/Phase 2 · REVOLUTION Medicines · Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS NCT05379985
Phase 3 · Sarepta Therapeutics, Inc. · A Gene Transfer Therapy Study to Evaluate the Safety and Efficacy of Delandistrogene Moxeparvovec (SRP-9001) in Non-Ambulatory and Ambulatory Participants With Duchenne Muscular Dystrophy (DMD) NCT05881408
Phase 1/Phase 2 · Starton Therapeutics · Safety, Efficacy, and Pharmacokinetics of Continuous Subcutaneous Lenalidomide in Multiple Myeloma (MM) NCT06087653
Phase 3 · Vertex Pharmaceuticals Incorporated · Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy NCT06628908
Phase 1 · Vividion Therapeutics · A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors NCT06004245
Phase 2 · ZetrOZ Systems · Long Duration High Frequency Ultrasound for the Treatment of Osteoarthritis NCT07515872

Jun 2027 (estimated) · 138 trials

Phase 1 · Ajax Therapeutics · A Phase 1 Study of LY5830966 in Participants With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Fai NCT06343805
Phase 2 · Akebia Therapeutics · A Study of Praliciguat in Participants With Focal Segmental Glomerulosclerosis (FSGS) NCT07268638
Phase 3 · Alkermes, Inc. · A Study to Evaluate the Efficacy, Safety and Tolerability of ALKS 2680 in Adults With Narcolepsy Type 1 (Brilliance NT1 - 304) NCT07540897
Phase not stated · Allarity Therapeutics · Clinical Pre-screening Protocol for Ovarian Cancer NCT03877796
Not applicable · Alpha Tau Medical · Alpha Radiation Emitters Device (DaRT) for the Treatment of Non-Metastatic Locally Recurrent Prostate Cancer. NCT06202248
Phase 1 · ALX Oncology · A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors NCT07085091
Not applicable · Anika Therapeutics · Integrity Implant System Post Market Clinical Follow-Up Study NCT06741527
Phase 4 · Apellis Pharmaceuticals, Inc. · A Prospective, Multicenter, Open-Label, Observational Phase 4 Study to Evaluate Real-World Safety, Tolerability, and Treatment Patterns of Pegcetacoplan (Syfovre) in Patients With Geographic Atrophy S NCT06161584
Phase 1 · Aprea Therapeutics · Study of APR-1051 in Patients With Advanced Solid Tumors NCT06260514
Phase 2 · Arcturus Therapeutics · Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis NCT06747858
Not applicable · Argá Medtech · Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation NCT06784466
Phase 1/Phase 2 · Arrowhead Pharmaceuticals · Study of ARO-MAPT-SC in Healthy Participants and Participants With Early Alzheimer's Disease NCT07221344
Phase 3 · Asklepion Pharmaceuticals · A Study of Intravenous L-Citrulline in Patients Aged 6-21 Years Old With Sickle Cell Disease Presenting to Emergency Departments in Acute Vaso-Occlusive Crisis NCT06989567
Phase 2 · Assembly Biosciences · A Study to Assess the Safety, Pharmacokinetics, and Efficacy of ABI-6250 in Participants With Chronic Hepatitis D Virus Infection NCT07762027
Phase 3 · Aurion Biotech · AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction NCT07368959
Phase 4 · Azurity Pharmaceuticals · Ambulatory Blood Pressure Monitoring (ABPM) Study in Hypogonadal Men NCT07328542
Phase 2 · Basking Biosciences · Study of BB-031 in Acute Ischemic Stroke Patients (RAISE) NCT06226805
Phase 2 · BeBetter Med · Study of BEBT-109 in Subjects With Non-Small Cell Lung Cancer Carrying EGFR Exon 20 Insertion Mutations NCT06514027
Phase not stated · Beta Bionics · The iLet Experience Study NCT06891898
Phase 2 · Biomea Fusion · Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Mellitus Who Are Not Achieving Glycemic Targets While Using GLP-1-Based Therapy NCT07502508
Phase 2 · BioNTech US Inc. · Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With Chemotherapy NCT06449209
Phase 2 · BioNTech US Inc. · A Randomized Clinical Trial Investigating the Safety, Reactogenicity, and Immunogenicity After Immunization With an mRNA-based Mpox Vaccine Candidate in Africa NCT07379580
Not applicable · Cochlear · A Study to Evaluate the Safety and Performance of a Vestibular Implant in Adults to Provide Balance Restoration NCT06805175
Phase 2 · ConSynance Therapeutics · A Study of CSTI-500 in Patients With Prader-Willi Syndrome NCT07348601
Phase 2 · Corvus Pharmaceuticals · Study to Evaluate Soquelitinib in Participants With Moderate to Severe AD NCT07441395
Phase 1 · CRISPR Therapeutics · A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias NCT07491172
Phase 1/Phase 2 · Cytoagents, Inc. · Study of CTO1681 for the Prevention and Treatment of CRS in Patients Receiving CAR T-Cell Therapy NCT05905328
Phase 3 · Day One Biopharmaceuticals · DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2) NCT05566795
Phase 2/Phase 3 · Denali Therapeutics · An Extension Study of the Long-Term Safety, Tolerability, and Efficacy of Tividenofusp Alfa (DNL310) in Participants With Mucopolysaccharidosis Type II (MPS II) From Study DNLI-E-0002 or Study DNLI-E- NCT06075537
Phase 2 · Direct Biologics · DB-3Q for the Treatment of Medically Refractory Crohn's Disease NCT07625293
Phase 1 · Disc Medicine · A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD) NCT07187973
Phase not stated · EBR Systems · WiCS-LV Post Market Surveillance Registry NCT02610673
Phase 2/Phase 3 · Electra Therapeutics · Open-label Study of ELA026 in Participants With Secondary Hemophagocytic Lymphohistiocytosis (sHLH) NCT05416307
Phase 2 · Eli Lilly · A Study of LY4005130 in Adult Participants With Severe Alopecia Areata (Hair Loss) NCT07533006
Phase 2 · Eli Lilly · A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's Disease NCT07483099
Phase 2 · Eli Lilly · A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's Disease NCT07483073
Phase 1 · Eli Lilly · A Study of Eloralintide (LY3841136) in Female Participants With Obesity or Overweight NCT07808060
Phase 3 · Genmab · A Study to Evaluate Change in Disease Activity of Subcutaneous (SC) Epcoritamab Combined With Intravenous and Oral Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone ( NCT05578976
Phase 3 · Gilead · Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadju NCT05633654
Not applicable · GT Metabolic Solutions · Side-to-Side Duodeno-ileostomy Versus Semaglutide in Adults With Obesity and Type 2 Diabetes NCT07317115
Not applicable · Healionics Corporation · Multi-Site STARgraft (10401) Trial NCT07557862
Phase 3 · Humacyte · To Compare the Efficacy and Safety of the ATEV With AVF in Female Patients With End-Stage Renal Disease Requiring Hemodialysis NCT05908084
Phase not stated · Impulse Dynamics · CCM and Implementation of Guideline-Directed Medical Therapy in Patients With Heart Failure (Fix-GDMT-HF) NCT06580392
Not applicable · JenaValve · ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™ NCT06608823
Phase 2 · Karyopharm Therapeutics Inc. · A Study of Selinexor Monotherapy in Subjects With JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia NCT05980806
Phase 2 · Kymera Therapeutics, Inc. · A Study of KT-621 Administered Orally to Participants With Moderate to Severe Atopic Dermatitis NCT07217015
Phase 3 · Lantheus Medical Imaging · [18F]PI-2620 Phase 3 Histopathological Study NCT05641688
Phase 3 · LB Pharmaceuticals · Study to Evaluate LB-102 for the Treatment of Adult Patients With Acute Schizophrenia NCT07363577
Not applicable · LeMaitre Vascular · A PMCF Study to Confirm the Performance and Safety of the LeMaitre® TufTex Single Lumen Embolectomy Catheter NCT05386277
Not applicable · LeMaitre Vascular · A PMCF Study Confirm the Performance and Safety of the TufTex Over-the-Wire (OTW) Embolectomy Catheters NCT05386342
Phase 2 · Locus Biosciences · A Study of LBP-EC01 in the Treatment of Acute Uncomplicated UTI Caused by Drug Resistant E. Coli (ELIMINATE Trial) NCT05488340
Phase 3 · Lupin · The Efficacy and Safety of Once Daily Mexiletine PR in Patients With Myotonic Dystrophy Type 1 and Type 2 NCT06523400
Not applicable · Micro Interventional Devices · The STTAR-US Study: A Pivotal Study of Transcatheter Tricuspid Annular Repair in the US NCT06700239
Phase 2 · MiNK Therapeutics · A Clinical Trial to Evaluate agenT-797 Plus Standard of Care in Participants With Severe Pneumonia With Moderate to Severe Acute Hypoxemic Respiratory Failure NCT07615010
Phase 1 · NeOnc Technologies · A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors NCT06357377
Not applicable · Novonesis · A Real-world Study of Gastrointestinal Health and Mental Wellness in U.S. Adults Following 12 Weeks of Probiotic Supplementation. NCT07849036
Phase 1 · ORIC Pharmaceuticals · Study of ORIC-944 in Patients With Metastatic Prostate Cancer NCT05413421
Phase 2 · Oruka Therapeutics · Dose Ranging Study of ORKA-001 in Patients With Moderate-to-Severe Plaque Psoriasis NCT07290569
Phase 3 · PleoPharma · Efficacy of PP-01 in Mitigating Cannabis Withdrawal Symptoms in Adults With Cannabis Use Disorder NCT07644052
Phase 1/Phase 2 · Recursion Pharmaceuticals · Evaluate REC-4881 in Participants With Familial Adenomatous Polyposis (FAP) NCT05552755
Phase 3 · Renibus Therapeutics · A Study to Evaluate the Efficacy and Safety of Veverimer for the Treatment of Metabolic Acidosis NCT07355062
Phase 3 · RenovoRx · Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC NCT03257033
Phase 1 · Revagenix · A Phase 1a/1b Study to Investigate the Safety, Tolerability, Microbiological Response, and Pharmacokinetics of Inhaled Rev-56 in Adult Healthy Volunteers and Adult Non-cystic Fibrosis Bronchiectasis ( NCT07709494
Phase 1/Phase 2 · REVOLUTION Medicines · Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC NCT06162221
Phase 3 · Savara Pharmaceuticals · Inhaled Molgramostim in Pediatric Participants With Autoimmune Pulmonary Alveolar Proteinosis (aPAP). NCT06431776
Phase 1 · Solid Biosciences Inc. · A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) NCT07148089
Phase not stated · SpotitEarly · Identification of Breast Cancer in Breath Samples Using Trained Detection Dogs NCT07038785
Phase 2 · Spyre Therapeutics · A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis NCT07012395
Phase 1/Phase 2 · Tango Therapeutics, Inc. · Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors NCT05732831
Phase 1/Phase 2 · Tango Therapeutics, Inc. · Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients NCT06922591
Phase 3 · Vedanta Biosciences, Inc. · VE303 for Prevention of Recurrent Clostridioides Difficile Infection NCT06237452
Phase 3 · Veradermics · Safety and Efficacy of VDPHL01 in Females With Androgenetic Alopecia (AGA) NCT07146022
Phase 2 · Verastem Oncology · A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer NCT07644559
Phase 2 · Verastem Oncology · A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer NCT07659795
Phase 2 · Verastem Oncology · A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Non-Small Cell Lung Cancer NCT07659782
Phase 3 · Verrica Pharmaceuticals · Cantharidin Application in Patients With Common Warts (Verruca Vulgaris) (COVE-2) NCT07246590
Phase 2 · Vima Therapeutics · A Study to Evaluate the Efficacy, PK, Safety, and Tolerability of VIM0423 in Adults With Parkinson's Disease Tremor Insufficiently Responsive to Dopaminergic Therapy NCT07804615
Phase 1/Phase 2 · Vironexis Biotherapeutics · Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19) NCT06533579
Phase 2 · vTv Therapeutics · Cadisegliatin as Adjunctive Therapy to Insulin in Participants With Type 1 Diabetes Who Are Using Hybrid Closed Loop (HCL) Systems NCT07616206
Phase 2 · Afasci, Inc. · A Study of the Safety and Exploratory Efficacy of Oral AFA-281 in Patients with Alcohol Use Disorder NCT06710431
Not applicable · Amplifi Vascular · Effect of the Amplifi™ Vein Dilation System on Outflow Vein Dilation and AV Fistula Maturation (AMPLIFI-1) NCT07211035
Phase 1/Phase 2 · Ascentage Pharma · APG-115 Alone or in Combination With APG-2575 in Recurrent or Refractory Neuroblastoma or Solid Tumors NCT05701306
Not applicable · Delve Bio · Investigation of the Delve Detect Cerebrospinal Fluid (CSF) Metagenomic Next-generation Sequencing (mNGS) Test When Used for the Initial Diagnostic Workup of Patients With Suspected Central Nervous Sy NCT07435649
Phase 1/Phase 2 · Eikon Therapeutics · A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors NCT06253130
Not applicable · ExThera Medical · OSCAR II STUDY - The ONCObind CTC Removal Study NCT06655142
Phase 3 · Insightec · Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets NCT05317858
Not applicable · Lucid Diagnostics · Efficacy of EsoGuard Assay on Esophageal Surface Cells Collected With EsoCheck vs EGD for the Diagnosis of BE or EAC NCT04295811
Phase not stated · Perosphere · Clinical Performance Evaluation of Native Whole Blood Samples of Patients on DOACs With the Perosphere ClotChek™ NCT07012291
Phase not stated · Spectral Md, Inc. · Deepview HHF Training and Validation Study NCT07677657
Not applicable · Theranica · An Open Label Study Assessing REN Treatment in Headache Management in Temporomandibular Disorders NCT07639944
Phase 1 · Tizona Therapeutics · TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers NCT04485013
Phase 1 · Lumen Bioscience · A Study of Intranasal LMN-1001 in Healthy Adults NCT07852208
Phase 3 · Vertex Pharmaceuticals Incorporated · Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Severe Sickle Cell Disease (SCD) NCT05329649
Phase 3 · Sanofi · Lot-to-lot Consistency Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From 2 Months of Age NCT07348692
Phase 1 · Bayer AG · A Study to Learn How Safe the Study Treatment Actinium-225-macropa-pelgifatamab (BAY3546828) is, How it Affects the Body, How it Moves Into, Through and Out of the Body, and About Its Anticancer Activ NCT06052306
Phase 1 · ViiV Healthcare · A Study to Investigate Pharmacokinetics, Safety and Tolerability of Long-Acting Cabotegravir Plus Recombinant Human Hyaluronidase PH20 in Healthy Adult Participants NCT05418868
Phase 3 · Novo Nordisk A/S · Research Study on How People With Type 2 Diabetes Tolerate Switching From Semaglutide to Cagrisema NCT07817251
Phase 3 · Vertex Pharmaceuticals Incorporated · Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease NCT05477563
Phase 2 · Merck & Co., Inc. · A Clinical Trial of MK-6916 in Participants With Pain After Bunion Removal Surgery (MK-6916-007) NCT07862595
Phase 1/Phase 2 · Merck & Co., Inc. · A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Program NCT05319730
Phase 2 · ViiV Healthcare · A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study) NCT07202546
Phase 3 · Boehringer Ingelheim · The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis NCT06872892
Phase 1/Phase 2 · CARsgen Therapeutics · Anti-GPRC5D CAR-T Cells (CT071) in Participants With RRMM or RRpPCL NCT06333509
Phase 2 · Enalare Therapeutics Inc. · ENA-001 for Post Operative Respiratory Depression (PORD) NCT06137638
Phase 1 · Neurona Therapeutics · A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE) NCT06422923
Phase 4 · Moderna · A Study to Evaluate the Efficacy and Safety of mRNA-1283 and mRNA-1273 in Participants 50 to 64 Years of Age Without High-Risk Conditions for Severe Coronavirus Disease 2019 (COVID-19) NCT07266558
Phase 1 · Bristol-Myers Squibb · A Study to Evaluate the Drug Levels, Absolute Bioavailability, Safety, Tolerability, and Immunogenicity of Single-Dose of BMS-986446 in Healthy Adults After Single-dose Administration, and Participant NCT07780383
Phase 2 · Sanofi · Study of Lunsekimig (SAR443765) Compared With Placebo in Adults With High-risk Asthma NCT06676319
Phase 4 · Alexion Pharmaceuticals, Inc. · Post-Marketing Clinical Study of Ravulizumab in Participants With Clinical aHUS NCT07308574
Phase 2 · Apellis Pharmaceuticals, Inc. · A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacopla NCT07215390
Phase 1 · Vertex Pharmaceuticals Incorporated · Dose Escalation Study Evaluating the Safety and Pharmacokinetics of VX-272 in Healthy Participants NCT07437105
Phase 1 · Bristol-Myers Squibb · A Study to Evaluate the Safety, Tolerability, and Drug Levels of BMS-986454 in Participants With Rheumatoid Arthritis NCT07171983
Phase 2 · AiViva BioPharma · Safety and Efficacy of AIV007 Periocular Injection in Patients With Neovascular Age-Related Macular Degeneration NCT07557121
Phase not stated · Alexion Pharmaceuticals, Inc. · Early Ravulizumab Treatment Of Anti- AChR Antibody-Positive Generalized Myasthenia Gravis NCT06967480
Phase 2 · Alnylam Pharmaceuticals · HMBeacon: A Phase 2 Study to Evaluate ALN-6400 in Adult and Adolescent Female Patients With VWD and HMB NCT07575308
Phase 3 · Amgen · A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous N NCT05920356
Phase 1 · Ankyra Therapeutics · A Study of Tolododekin Alfa (ANK-101) in Combination With an Anti-PD-1/PD-L1 Antibody in Participants With Advanced Non-Small Cell Lung Cancer NCT07027514
Not applicable · Aqua Medical · Safety, Tolerability, and Effectiveness of Duodenal Mucosal RF Vapor Ablation for Insulin Elimination in Type-2 Diabetes NCT06655740
Not applicable · Aqua Medical · RF Vapor Ablation Retreatment of Duodenal Mucosa in Non-responders With Type-2 Diabetes Mellitus NCT06724822
Phase 3 · Ascentage Pharma · Study of Olverembatinib (HQP1351) in Patients With CML-CP NCT06423911
Phase 4 · Astellas · A Study About the Safety of ASP3021 Eye Injections and if They Help People in Japan With Vision Loss From Age-related Macular Degeneration NCT06970665
Phase not stated · Bayer AG · A Study to Learn More About the Long-term Safety and Effectiveness of Molidustat as a Treatment for Japanese Men and Women With Renal Anemia NCT04899661
Phase not stated · Becton Dickinson · An Observational, Multinational, In Hospital Evaluation of Catheter Utilization Rates in Female Patients Using Indwelling Urinary Catheters and the PureWick™ Flex Female External Catheter Across Europ NCT07798128
Phase 3 · Belite Bio · Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Geographic Atrophy NCT05949593
Phase 1 · Cellectar Biosciences, Inc. · Novel Targeted Radiotherapy in Pediatric Patients With Inoperable Relapsed or Refractory HGG NCT05610891
Phase 1 · Cellectar Biosciences, Inc. · Dose Escalation Study of CLR 131 in Pediatric Relapsed/Refractory Malignant Tumors Including Neuroblastoma and Sarcomas NCT03478462
Phase 1 · ENSEM Therapeutics · Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors NCT06993844
Not applicable · Field Medical · The Field PULSE Study NCT06452589
Phase 2 · IMUNON · Phase II IMNN-001 (Also Known as GEN-1) on SLL With BEV and NACT, Newly Diagnosed Advanced Ovarian, Fallopian Tube or Primary Peritoneal Cancer NCT05739981
Phase 3 · Mirum Pharmaceuticals · A Trial Evaluating Brelovitug (BJT-778) vs Bulevirtide for the Treatment of Chronic Hepatitis Delta Infection (AZURE-2) NCT07200908
Phase 2 · Nuvig Therapeutics · Safety, Tolerability, and Efficacy of NVG-2089 in Participants With Immune Thrombocytopenia NCT07095127
Phase 2 · NuvOx Therapeutics · A Study of NanO2™ Combined With Radiation and Temozolomide in Patients With Newly Diagnosed GBM NCT03862430
Phase 1/Phase 2 · OncoC4 · Safety, Pharmacokinetics, and Efficacy of AI-081, a Bispecific Antibody for PD-1 And VEGF in Advanced Solid Tumors NCT06635785
Not applicable · Pulmonx · An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema NCT06035120
Phase 3 · StemCyte · A Study of Human Umbilical Cord Blood (REGENECYTE) Infusion in Patients With Post-COVID Condition NCT07184385
Phase 1 · Sumitomo Pharma America, Inc. · A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1) NCT04988555
Phase not stated · Takeda · A Survey to Assess Participants', Caregivers', and Nurses' Use and Understanding of Educational Material on Velaglucerase Alfa (VPRIV) Home Infusion NCT05669729
Phase 2 · XyloCor Therapeutics Inc. · Investigational Trial to Evaluate XC001 Delivered Via an Cardiac Catheter in Subjects With Chronic Angina. NCT07048808

Jul 2027 (estimated) · 81 trials

Phase 2 · Alkermes, Inc. · A Study to Evaluate Safety and Efficacy of ALKS 7290 Compared With Placebo in Adult Participants With Attention Deficit Hyperactivity Disorder (ALKS 7290-201) NCT07755410
Phase 3 · Amicus Therapeutics · A Study to Evaluate the Safety, Efficacy, PK, PD and Immunogenicity of Cipaglucosidase Alfa/Miglustat in IOPD Subjects Aged 0 to <18 NCT04808505
Phase 2 · Amydis Diagnostics · A Study of AMDX-2011P in Participants With Alzheimer's Disease NCT06514001
Phase 2 · Anagram Therapeutics · Phase 2 Study to Assess the Safety and Efficacy of ANG003 NCT07450547
Phase 3 · Apellis Pharmaceuticals, Inc. · An Open-Label, Nonrandomized, Multicenter Extension Study to Evaluate the Long-term Safety and Efficacy of Pegcetacoplan in Participants With C3 Glomerulopathy or Immune-Complex Membranoproliferative NCT05809531
Phase 1 · Bio-Path Holdings · BP1001-A in Patients With Advanced or Recurrent Solid Tumors NCT04196257
Phase 1 · Biohaven · Study of BHV-1400 in IgA Nephropathy NCT07054684
Phase 1/Phase 2 · Cilcare · A Study Testing the Safety and Possible Benefits of an Ear Injection of a New Compound, Paliroden, in People With Type 2 Diabetes Who Have Difficulty Understanding Speech in Noisy Situations NCT07472907
Not applicable · Cochlear · Evaluating How a Tinnitus Implant Affects Tinnitus Loudness in Adults With Chronic Tinnitus and Varying Levels of Hearing Loss NCT06641999
Phase 2 · Crystalys Therapeutics · A Phase 2 Trial of Dotinurad in Xanthine Oxidase Inhibitor (XOI) Intolerant/Uricase Failure Gout Participants NCT07535034
Phase 1/Phase 2 · Curis · CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL) NCT03328078
Phase 1 · Dren Bio · A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas NCT06999187
Not applicable · Edwards Lifesciences · ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve NCT05172960
Phase 2 · Eli Lilly · A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C) NCT07545772
Phase not stated · Emergent BioSolutions · Observational Study Evaluating Clinical Benefit and Safety of AIGIV (ANTHRASIL®) in Patients With Systemic Anthrax NCT03569514
Phase not stated · Emergent BioSolutions · A Field Study Evaluating Clinical Benefit and Safety of AIGIV (ANTHRASIL®) in Inhalational Anthrax Patients NCT03569553
Phase 1/Phase 2 · Genmab · Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001) NCT05579366
Phase 1/Phase 2 · Incyclix Bio · Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer NCT05735080
Not applicable · Insightec · EMBRACE Tremor BiFUS NCT06974916
Phase 3 · Intellia Therapeutics · A Phase 3 Study of NTLA-2001 in ATTRv-PN NCT06672237
Not applicable · InterVene · RECANA OUS - Recana Thrombectomy Catheter System for Venous Obstruction and Occlusion Study (RECANA-OUS-UK) NCT07219758
Not applicable · iVEAcare · Feasibility Study of the iVEAcare Neuromodulation System for the Treatment of Drug-Resistant Epilepsy NCT07640191
Phase 1 · Janux Therapeutics · Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01) NCT05519449
Phase 1/Phase 2 · Krystal Biotech · A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors NCT05970497
Phase not stated · Lexeo Therapeutics · A Study to Assess Real-world Patient Characteristics and Clinical Course for Symptomatic Patients With PKP2-ACM NCT06976606
Phase 2 · MacroGenics · A Study of Lorigerlimab in Participants With Advanced Solid Tumors NCT06730347
Phase 3 · Mesoblast · Efficacy and Safety of Rexlemestrocel-L Combined With HA* in Participants With Moderate to Severe Chronic Low Back Pain NCT06325566
Phase not stated · Nanoscope Therapeutics · Non-Interventional Long Term Follow-up Study of Participants Previously Enrolled in the RESTORE Study NCT06162585
Phase not stated · PainTEQ · Post-Market Clinical Study Using TRAQ™ for Minimally Invasive Posterior Sacroiliac Joint Fusion NCT07547215
Not applicable · Procept BioRobotics · WATER IV Prostate Cancer NCT06651632
Phase 1/Phase 2 · Q Therapeutics · Study to Investigate the Safety of the Transplantation of Human Glial Restricted Progenitor Cells Into Subjects With Transverse Myelitis NCT03887273
Phase 1 · RayzeBio · Study of RYZ101 in Combination With SoC in Subjects With SSTR+ ES-SCLC NCT05595460
Phase 2 · Reunion Neuroscience · RE104 Safety and Efficacy Study in Generalized Anxiety Disorder NCT07489651
Not applicable · Shape Memory Medical · AAA-SHAPE Pivotal Trial: Abdominal Aortic Aneurysm Sac Healing and Prevention of Expansion NCT06029660
Not applicable · Shockwave Medical · Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II NCT05102019
Phase 1/Phase 2 · Travere Therapeutics · Pegtibatinase as a Treatment for Patients With Classical Homocystinuria (HCU) (Also Known as the COMPOSE Study) NCT03406611
Phase not stated · Zimmer Biomet · Zimmer Biomet-RibFix Titan NCT07485829
Phase 2 · E-Star BioTech · To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension NCT06343298
Phase 2 · EpicentRx · RRx-001 for Reducing Oral Mucositis in Patients Receiving Chemotherapy and Radiation for Head and Neck Cancer NCT05966194
Not applicable · Nexalin Technology · HALO Clarity™ Cranial Alternating Current Stimulation Therapy for Adults With Moderate-to-Severe Insomnia NCT07659366
Phase 1 · Quanta Therapeutics · QTX3046 in Patients With KRAS G12D Mutations NCT06428500
Phase 3 · Viking Therapeutics · VK2735 for Weight Management Type 2 Diabetes Phase 3 (VANQUISH 2) NCT07104383
Phase 3 · Viking Therapeutics · VK2735 for Weight Management Phase 3 NCT07104500
Phase not stated · Zimmer Biomet · Prospective G7 Dual Mobility Total Hip PMCF NCT03308929
Phase 2 · Alexion Pharmaceuticals, Inc. · Study of ALXN1920 in Adult Participants With Primary Membranous Nephropathy (PMN) NCT07157787
Phase 1/Phase 2 · Epicrispr Biotechnologies · A First-in-human Study of EPI-321 in Facioscapulohumeral Muscular Dystrophy NCT06907875
Phase 2 · Kailera Therapeutics · Efficacy and Safety of Oral KAI-7535 in Adult Participants Living With Obesity or Overweight With at Least 1 Weight-Related Comorbidity NCT07497880
Phase 3 · Sanofi · A Study to Test the Efficacy and Safety of Riliprubart Against the Usual Treatment of Intravenous Immunoglobulin (IVIg) in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) NCT06290141
Phase 4 · Takeda · A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC) NCT06095128
Phase not stated · Edwards Lifesciences · CLAARITY is a Prospective, Observational, Single-arm, Multi-center, Post-market US Study Designed to Evaluate the Safety and Performance of the ECLIPTIS Left Atrial Appendage Exclusion System for Excl NCT07742839
Phase not stated · Natera · Evaluation of the Natera Colorectal Cancer Screening Test in an Average Risk Population (FIND-CRC) NCT07046585
Phase 1 · PeproMene Bio · BAFFR-targeting CAR T Cells for Patients With Relapsed or Refractory B-NHL NCT05370430
Phase 4 · Bayer AG · A Study to Learn More About the Change in the Blood Levels of Transthyretin When Participants With Transthyretin Amyloidosis With Cardiomyopathy Switch From Tafamidis to Acoramidis NCT07298044
Phase 1/Phase 2 · GV20 Therapeutics · Study of GV20-0251 in Participants With Solid Tumor Malignancies NCT07070518
Phase 1 · HCW Biologics · HCW9302 (Interleukin-2 Fusion Protein) for Alopecia Areata NCT07049328
Phase 1 · Lifordi Immunotherapeutics · Study of LFD-200 in Healthy Adults and Adults With Moderate to Severe Rheumatoid Arthritis NCT07207954
Phase 2 · Novartis · A Study of JSB462 (Luxdegalutamide) Plus Lutetium (177Lu) Vipivotide Tetraxetan in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC) NCT07047118
Phase 3 · Boehringer Ingelheim · A Study to Test Whether Nerandomilast Helps People With Lung Fibrosis Related to Rheumatic Diseases NCT06806592
Phase 1 · Bristol-Myers Squibb · Study to Assess Drug Levels, Immune Response, Safety and Tolerability of BMS-986446 in Healthy Chinese Participants. NCT07852962
Phase 1/Phase 2 · Daiichi Sankyo · A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03) NCT06362252
Phase 1 · Moderna · A Study to Investigate Safety, Reactogenicity, and Immunogenicity of mRNA-1365 (Profile 2) in Older Healthy Adults NCT07764237
Phase 2 · Vertex Pharmaceuticals Incorporated · Phase 2a Study of VX-407 in Participants With ADPKD Who Have a Subset of PKD1 Gene Variants (AGLOW) NCT07161037
Phase 1 · Incyte · Study of INCB123667 in Subjects With Advanced Solid Tumors NCT05238922
Phase 1 · Thetis Pharmaceuticals LLC · Phase 1b Clinical Study in Patients With Active Ulcerative Colitis NCT07834515
Phase 2 · Direct Biologics · DB-3Q bmMSC-EVs in Patients With Perianal Fistulizing Crohn's Disease NCT06918808
Phase 3 · Genmab · Trial to Evaluate Acasunlimab and Pembrolizumab Combination Superiority Over Standard of Care Docetaxel in Non-Small Cell Lung Cancer (ABBIL1TY NSCLC-06) NCT06635824
Phase 1 · IDEAYA Biosciences · A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types NCT07503808
Phase 4 · Rigel Pharmaceuticals · Pralsetinib DDI Study in Patients With Advanced or Metastatic Solid Tumors NCT07704658
Phase 2 · Throne Biotechnologies · Clinical Application of Stem Cell Educator Therapy in Alopecia Areata NCT04011748
Phase 1 · Alnylam Pharmaceuticals · A Study to Evaluate ALN-4915 in Adult Healthy Volunteers NCT07535606
Phase 3 · Amgen · A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration NCT07614776
Phase 3 · Annexon Biosciences · A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections of Vonaprument (Formerly ANX007) in Participants With Dry Age-Related Macular Degeneration (AMD) With Geographic Atrophy NCT06510816
Phase 1 · BioXcel Therapeutics · Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder NCT05025605
Phase not stated · Daiichi Sankyo · Real-world Effectiveness and Safety of Trastuzumab Deruxtecan in Patients With Locally Advanced or Metastatic HER2-positive Gastric or Gastroesophageal Junction Adenocarcinoma in China NCT06846996
Phase 1/Phase 2 · Estrella Immunopharma · T-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL) NCT06343311
Phase not stated · Liquidia · An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprostinil in PH NCT06129240
Phase 3 · MAIA Biotechnology · A Phase III Study With THIO + Cemiplimab vs Chemotherapy as 3rd Line Treatment in Advanced/Metastatic NSCLC NCT06908304
Phase 1 · NiKang Therapeutics · A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors NCT07029399
Phase 1 · Persevere Therapeutics · A Trial to Evaluate Safety, Tolerability, and Preliminary Efficacy of Misetionamide (GP-2250) as Monotherapy or in Combination With Gemcitabine NCT03854110
Phase 3 · Shionogi · Study of Secutrelvir in Participants With COVID-19 NCT07746544
Phase 2 · Stingray Therapeutics Inc. · Phase 2 Study of SR-8541A in Combination With Botensilimab and Balstilimab in Subjects With Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC) NCT06589440

Aug 2027 (estimated) · 105 trials

Phase not stated · Acera Surgical · A Prospective, Single-arm, Clinical Trial of Electrospun Fiber Matrix (Restrata) in the Treatment of Surgical Defects Secondary to Resection of Malignant Cutaneous Neoplasms NCT06578650
Phase 2 · AOBiome · Study to Determine Efficacy, Safety, and Tolerability of B244 as a Topical Spray in Subjects With Moderate to Severe Acne Vulgaris NCT07866105
Phase 4 · Applied Biologics · A Multicenter, Prospective, Controlled Clinical Trial Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers NCT07159282
Phase 4 · Applied Biologics · A Multicenter, Prospective, Clinical Trial Evaluating a Single Layer Amniotic Membrane and Standard of Care Versus Matched Controls in the Management of Nonhealing Pressure Ulcers NCT07126886
Phase 1 · ArriVent Biopharma · Phase 1 Study to Assess Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Antitumor Activity of ARR-002 in Advanced or Metastatic Ovarian or Endometrial Cancer. NCT07755436
Phase 1 · Artiva Biotherapeutics · AB-101 in Combination With B-Cell Depleting mAb in Patients Who Failed Treatment for Class III or IV Lupus Nephritis or Other Forms of Refractory Systemic Lupus Erythematosus NCT06265220
Phase 3 · Ascentage Pharma · A Study of Lisaftoclax (APG-2575) Combined With Acalabrutinib Versus Immunochemotherapy for Newly Diagnosed CLL/SLL. NCT06319456
Not applicable · Autonomous Healthcare Inc. · Feasibility Study of E-Fusion Vasopressor Titration-Assist During Multi-Level Spine Surgery NCT07840937
Phase 2/Phase 3 · Biohaven · A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease NCT06976268
Phase 1 · Climb Bio · A Phase 1b/2a Study of Budoprutug in Subjects With Immune Thrombocytopenia (ITP) NCT07043946
Phase 2 · Convergent Therapeutics · Study Evaluating Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan in Participants With PSMA PET-Positive Castration-Resistant Prostate Cancer (CRP NCT06549465
Phase 1 · Corsera Health · A Study to Evaluate COR-2003 as Monotherapy and Co-Administered With COR-1004 in Adult Volunteers NCT07858019
Phase 3 · Crinetics Pharmaceuticals, Inc. · Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen NCT07087054
Phase 1/Phase 2 · Crinetics Pharmaceuticals, Inc. · A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors NCT07129252
Phase 3 · DalCor Pharmaceuticals · Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS NCT05918861
Phase 1 · Eli Lilly · A Study of LY5625575 in Healthy Participants and in Participants With Inflammation (Elevated C-Reactive Protein) NCT07801300
Phase not stated · Emergent BioSolutions · VA-005 Clinical Outcomes of VIGIV Treatment of Smallpox Vaccination Complications or Vaccinia Infection NCT01374984
Phase 2 · Emmecell · Study of EO2002 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction NCT07729137
Not applicable · Field Medical · This Study Will Evaluate if the Field Force Pulsed Field Ablation System is Safe and Effective for Treating Sustained Monomorphic Ventricular Tachycardia, a Potentially Serious Fast Heart Rhythm of th NCT07794215
Phase 2 · Genfit · Phase 2 Study of 500 mg BID NTZ on Top of Standard of Care in Patients With Acute Decompensation of Liver Cirrhosis at High Risk of Progression to Acute-on-Chronic Liver Failure or Established Acute-o NCT07694297
Phase 1 · Genmab · A Safety Trial of GEN1042 in Japanese Subjects With Malignant Solid Tumors NCT06057038
Phase 2 · Gilead · Substudy-01: A Study of Long-Acting HIV-1 Treatments Taken by Mouth in People With HIV-1 With Undetectable Virus Levels NCT07841990
Phase 2 · Gilead · A Study of GS-3242 in Combination With Lenacapavir Versus Biktarvy in Virologically Suppressed People With HIV-1 NCT07645287
Not applicable · Holobiome, Inc. · GUT-FEELINGS: Using Citizen Science for Large-Scale Prebiotic Clinical Trials for Mental Health in Adults NCT07752823
Phase not stated · iSono Health · ATUSA Ultrasound Diagnostic Imaging for Breast Lesions Evaluation (AUDIBLE) - iSono Health NCT07505797
Phase 2 · Kiora Pharmaceuticals · A Phase II Study of Intravitreal KIO-301 in Patients With Late-stage Retinitis Pigmentosa NCT06628947
Phase 1 · Korro Bio · Phase 1/2 Study of KRRO-121 in Healthy Volunteers and Patients With UCD NCT07773246
Phase 1/Phase 2 · Lantheus Medical Imaging · Lu-TARGO (177Lu-TARGeted Osteosarcoma Therapy) NCT07357519
Phase 3 · Lipocine · Brexanolone Lifting Outcomes Of Moms NCT07822321
Phase 2 · Marea Therapeutics · A Study to Evaluate MAR002 for Acromegaly NCT07641179
Phase 2 · Mediar Therapeutics · WISPer: Evaluation of MTX-463 in Participants With Idiopathic Pulmonary Fibrosis (IPF) NCT06967805
Phase 1 · NextPoint Therapeutics · A Study of NPX887 for Participants With Solid Tumors Known to Express B7-H7/HHLA2 NCT06240728
Phase 2 · Novelmed Therapeutics Inc · Study of Efficacy and Safety of NM8074 in Adult PNH Patients Who Are Naive to Complement Inhibitor Therapy NCT05646524
Phase 1 · Nuvectis Pharma · Study of NXP900 With Lorlatinib in ALK+ Lung Cancer NCT07784959
Phase 3 · Opus Genetics Inc · OPI-NXYDLD-303 Safety and Efficacy of Phentolamine Ophthalmic Solution in Keratorefractive Surgery Participants With Decreased Mesopic Visual Acuity NCT07140783
Phase not stated · Ossium Health Inc. · HPC Offered for PRESERVE Expansion NCT07145411
Phase 3 · Otsuka · A Long-term Trial of EB-1020 in Pediatric Patients With ADHD NCT07087327
Phase 2/Phase 3 · Otsuka · A Trial to Evaluate the Efficacy and Safety of EB-1020 in Pediatric Patients With ADHD NCT07086313
Phase 2 · Palvella Therapeutics · A Phase 2, Baseline-Controlled Study Evaluating the Safety and Efficacy of PTX-022 (Sirolimus) Topical Gel 3.9% in the Treatment of Angiokeratomas (LOTU) NCT07552077
Phase not stated · Paragonix Technologies · Global Utilization And Registry Database for Improved preservAtion of doNor Livers NCT05082077
Early phase 1 · Piezo Therapeutics, Inc. · PIEZO-101 First-in-Human Safety and Proof-of-Concept Study NCT07671027
Early phase 1 · RayzeBio · Imaging Study in Metastatic UC, HR+ and HER2- Breast Cancer, TNBC, and NSCLC NCT07671092
Not applicable · ReVivo Medical · CEM-Plate and CEM-Cage First-In-Human Use Efficacy Study NCT04883411
Not applicable · Rivanna Medical · Accuro XV Ultrasound Imaging System for BoneEnhance and Fracture Detection Algorithms NCT07853768
Phase 3 · Sagimet Biosciences · Phase 3 Study of Denifanstat in Participants With Moderate to Severe Acne NCT07863193
Phase 1 · Solve Therapeutics · SLV-154 Treatment of Advanced Cancers NCT06771219
Phase 2 · Supernus Pharmaceuticals · RENAISSANCE 2: SPN-817 Phase 2, Double-Blind, Placebo-Controlled Study in Adults With Focal Onset Seizures NCT06798896
Phase 1/Phase 2 · Tenaya Therapeutics · Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM NCT05836259
Phase 2 · Tortugas Neuroscience · A Study of the Safety and Efficacy of TRTL-913 in Healthy Volunteers (Part A) and in Adults With Tinnitus (Part B) NCT07777549
Phase 3 · Travere Therapeutics · Pegtibatinase as a Treatment for Participants With Classical Homocystinuria (HCU) Receiving Standard of Care Treatment NCT06247085
Phase 3 · Trevi Therapeutics · Idiopathic Pulmonary Fibrosis (IPF)-Related Chronic Cough Reduction With Nalbuphine (NAL) Extended-Release (ER) Tablets NCT07868419
Phase 2 · Triveni Bio · A Study Evaluating TRIV-573 in Atopic Dermatitis NCT07782333
Phase 3 · Ultragenyx Pharmaceutical · A Study to Determine the Effect of Triheptanoin Compared With Even-Chain MCT on MCEs in Pediatric Patients With LC-FAOD NCT05933200
Phase 3 · Ultragenyx Pharmaceutical · Follow-up Study of AAV-Mediated Gene Transfer (UX111; Previously Known as ABO-102) for MPS Type IIIA NCT04360265
Phase 1 · Vaxiion Therapeutics · Phase 1 Study of Intratumoral Administration of VAX014 With Expansion in Combination With a Checkpoint Inhibitor in Subjects With Advanced Solid Tumors NCT05901285
Phase not stated · Zimmer Biomet · Affixus Natural Nail System Humeral Nail PMCF NCT05019664
Phase 1 · Continuity Biosciences · A First-in-Human Study to Evaluate Implantable Iontophoresis Chemotherapy Delivery Device With Gemcitabine Once Weekly or Twice Weekly in Participants With Pancreatic Cancer NCT07481383
Phase 4 · Jazz Pharmaceuticals · Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution NCT05044819
Not applicable · Koronis Biomedical Technologies · Portable Positive Pressure Therapy Device NCT04452851
Phase 1 · Novo Nordisk A/S · A Study to See How Safe a New Medicine (NNC0705-0002) is in Healthy People NCT07797855
Phase 1 · OncoC4 · Safety, Pharmacokinetics (PK), and Efficacy of ONC-783 in Advanced Solid Tumors NCT07408258
Phase not stated · Supernus Pharmaceuticals · Real-World Patient Experiences Using Continuous Subcutaneous Apomorphine Infusion (ONAPGOTM) in the United States: NCT07219927
Not applicable · Theranica · The Effect of Remote Electrical Neuromodulation (REN) on Conditioned Pain Modulation (CPM) in Migraine and Fibromyalgia NCT07841509
Phase 1/Phase 2 · Triumvira Immunologics · TAC T-cells for the Treatment of Claudin 18.2 Positive Solid Tumors (TACTIC-3) NCT05862324
Phase 2 · Verastem Oncology · Continued Access to Avutometinib in Combination With Defactinib in Patients With Recurrent Low-Grade Serous Ovarian Cancer (LGSOC) NCT07747506
Phase 1 · Vividion Therapeutics · A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-159642 in Participants With Advanced Solid Tumors NCT06804824
Phase 2 · ImmunityBio · NAI for Sepsis With Persistent Lymphopenia NCT07578558
Phase 1 · Moderna · A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer Agents in Participants With Solid Tumors NCT06880549
Phase 2 · Boehringer Ingelheim · A Study to Test Whether BI 3802876 is Tolerated in People With Compensated Liver Cirrhosis Due to Metabolic Dysfunction- Associated Steatohepatitis (MASH) NCT07325526
Phase 3 · Biogen · A Study of BIIB067 (Tofersen) Initiated in Clinically Presymptomatic Adults With a Confirmed Superoxide Dismutase 1 Mutation NCT04856982
Phase 2 · Shionogi · Study of S-606001 as an Add-on to Enzyme Replacement Therapy (ERT) in Participants With Late-onset Pompe Disease (LOPD) NCT07123155
Phase 2 · Alnylam Pharmaceuticals · A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy NCT06393712
Phase 1 · Boehringer Ingelheim · A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With a Tumour in the Brain That is Positive for DLL3 NCT05916313
Phase 1 · Lineage Cell Therapeutics · A Study to Evaluate the Safety of a Delivery Device for Administering LCTOPC1 in Participants With Spinal Cord Injury NCT06841770
Phase 1 · Novartis · Dose Finding Study of [177Lu]Lu-NeoB in Newly Diagnosed Glioblastoma and in Recurrent Glioblastoma NCT05739942
Phase 1/Phase 2 · Acrivon Therapeutics · Study of ACR-2316 in Specific Advanced Solid Tumors NCT06667141
Phase not stated · Alexion Pharmaceuticals, Inc. · A Study About the Natural History in Adults With BAG3 Dilated Cardiomyopathy (a Type of Heart Disease) (BAG3 DCM) NCT05981092
Phase 1 · Eilean Therapeutics · A First-in-Human Study of ZE66-0205 in Healthy Volunteers NCT07735728
Not applicable · Linshom · Clinical Evaluation of an Alarm Activated Detection System to Enable Early Intervention of Emerging Respiratory Decline With the Linshom Medical Continuous Predictive Respiratory Sensor (CPRS) NCT07793981
Phase 3 · Alexion Pharmaceuticals, Inc. · Efficacy and Safety of Ravulizumab in Chinese Adults Participants With Generalized Myasthenia Gravis (gMG) NCT07596784
Phase 1/Phase 2 · Ipsen · A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Moderate to Severe Upper Facial Lines NCT04821089
Phase 3 · Amgen · Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy NCT07225686
Phase 3 · Arrowhead Pharmaceuticals · A Phase 3 Study of Zodasiran in Adolescent and Adult Subjects With Homozygous Familial Hypercholesterolemia (YOSEMITE) NCT07037771
Phase 4 · BioNTech US Inc. · A Study to Learn About a COVID-19 Vaccine in Healthy Adults 18 Through 64 Years of Age NCT07730450
Phase 2 · LyGenesis · Allogenic Hepatocyte Transplantation Into Periduodenal Lymph Nodes NCT04496479
Phase 2 · Alveus Therapeutics · Study to Assess the Effect and Safety of ALV-100 on Maintenance of Weight Loss NCT07837973
Phase 2 · Amgen · A Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat and Obesity or Overweight NCT07441252
Phase 4 · Novo Nordisk A/S · A Research Study to See How Safe is Eptacog Alfa When Used to Stop Heavy Bleeding in Women After Giving Birth in India NCT07157423
Phase 4 · Alexion Pharmaceuticals, Inc. · A Study to Investigate OCS Tapering in Adult Participants With Generalized Myasthenia Gravis Treated With Ravulizumab NCT07221838
Phase 2 · RyCarma Therapeutics · A Trial to Compare Treatment With Surlorian (ARM210, S48168) to Placebo in Effects on Muscle Strength and Safety in Adults With Autosomal Dominant RYR1-related Myopathy NCT07560020
Phase 3 · Amgen · Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy NCT07226765
Phase 3 · Sofie · Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Gastric or Esophageal Cancer. NCT07217704
Phase 1/Phase 2 · Alnylam Pharmaceuticals · A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM NCT06845202
Phase not stated · Ascidian Therapeutics · Prescreening Study to Identify Potential Stargardt Participants for ACDN-01 Clinical Trials (STARPATH) NCT06445322
Not applicable · AtaCor Medical · Parasternal Extravascular ICD System Pivotal Clinical Investigation (ALARION EV) Study NCT07324031
Phase 1 · Boehringer Ingelheim · A Study to Test Whether Treatment With BI 770371 in Combination With Pembrolizumab With or Without Cetuximab Helps People With Head and Neck Cancer Compared With Pembrolizumab Alone NCT06806852
Phase 2/Phase 3 · Compass Therapeutics · A Study of CTX-009 in Combination With Paclitaxel in Adult Patients With Unresectable Advanced, Metastatic or Recurrent Biliary Tract Cancers (COMPANION-002) NCT05506943
Phase 2/Phase 3 · Mirum Pharmaceuticals · Study to Evaluate Switching to Brelovitug for the Treatment of CHD in Participants Receiving Bulevirtide NCT07454837
Phase 1/Phase 2 · Moderna · Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia NCT04159103
Phase not stated · Novartis · A Real-world Study of the Effectiveness of Angiotensin Receptor-Neprilysin Inhibitor Therapy in Hypertensive Patients in the United Arab Emirates NCT07465666
Phase 3 · OncoC4 · ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors NCT05671510
Phase 4 · Sarepta Therapeutics, Inc. · Study to Evaluate the Safety and Effectiveness of ELEVIDYS in Participants With Duchenne Muscular Dystrophy Treated in a Post-Marketing Setting NCT07542314
Not applicable · Spark Biomedical, Inc. · tAN for Substance Use Disorder NCT07281261
Not applicable · Spark Biomedical, Inc. · Delivering tAN to Reduce HMB: The LUNA Study NCT07326722
Phase not stated · ZimVie · The Tether™ - Vertebral Body Tethering System Post Approval Study NCT04505579

Sep 2027 (estimated) · 102 trials

Phase 2 · Agenus Inc. · A Study of Botensilimab and Balstilimab for the Treatment of Colorectal Cancer NCT05608044
Phase 3 · Alkermes, Inc. · Long-term Safety Extension Study of OLZ/SAM in Pediatric Subjects NCT04987229
Phase 1 · Arcus Biosciences · Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers NCT05891171
Phase 4 · Azurity Pharmaceuticals · Study of the Pharmacokinetics, Safety, and Tolerability of ZONISADE in Children 1 Month to 17 Years of Age With Partial-onset Seizures NCT06534502
Not applicable · Bausch + Lomb · A Study to Investigate the Safety and Effectiveness of the Technolas® TENEO 317 Model 2 Excimer Laser for Laser In Situ Keratomileusis (LASIK) Surgery to Treat Myopia or Myopic Astigmatism NCT07377474
Phase not stated · Berlin Heart · Registry to Assess the Safety and Feasibility of the Subpulmonary Support with the Novel Venous Cannula in Patients with Failing/Absence of the Right Heart NCT04782232
Phase 1 · Biohaven · Study of BHV-1300 in Graves' Disease NCT06980649
Phase 1 · Carna Biosciences · AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma NCT05602363
Phase 3 · Castle Creek Biosciences · Evaluation of D-Fi for the Treatment of Wounds Due to DEB NCT06892639
Phase 1 · Cenna Biosciences · Phase 1 Study to Evaluate the Safety and Tolerability of 8M2D in Healthy People and Alzheimer's Patients NCT07568041
Phase 1 · Climb Bio · A Phase 1b/2a Study of Budoprutug in Systemic Lupus Erythematosus (SLE) NCT07564596
Phase 2 · Coherus Oncology · A Trial of Casdozokitug in Combination With Toripalimab Plus Bevacizumab in Participants With Unresectable and/or Locally Advanced or Metastatic Hepatocellular Carcinoma NCT06679985
Phase not stated · ConvaTec · A Study on the Efficacy and Safety of a Nitric Oxide Generating Dressing in the Treatment of Diabetes Related Foot Ulcers. NCT07438951
Phase 2 · Corcept Therapeutics · Relacorilant With Nab-Paclitaxel and Gemcitabine in Patients With Metastatic Pancreatic Adenocarcinoma NCT07259317
Phase 3 · Cytokinetics · Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction NCT06736574
Phase not stated · Deciphera Pharmaceuticals, LLC · MOVE: Tenosynovial Giant Cell Tumor (TGCT) Real-World Participant Experience With Vimseltinib NCT07075471
Phase 2 · Elevar Therapeutics · A Study of Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement NCT07359820
Phase 1 · Eli Lilly · A Study of LY4329090 in Participants With Obesity or Overweight Who Are Otherwise Healthy NCT07808073
Phase 2 · Eli Lilly · A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Diarrhea (IBS-D) NCT07545759
Phase 2 · Eli Lilly · A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight NCT07589608
Phase not stated · Exact Sciences · First CORRECT Study of Minimal Residual Disease (MRD) Detection in Colorectal Cancer NCT06398743
Phase 3 · Genmab · An Extension Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in Participants With Platinum Resistant Ovarian Cancer in China NCT07604766
Phase 1/Phase 2 · Genmab · Trial of the Safety and Efficacy of Epcoritamab in Japanese Subjects With Relapsed or Refractory (R/R) B-Cell Non-Hodgkin Lymphoma (R/R B-NHL) NCT04542824
Phase 4 · Glaukos · Evaluate the Safety and Feasibility of Same-Day Bilateral Epithelium-On Corneal Cross-Linking for Keratoconus NCT07629557
Phase 1/Phase 2 · Immatics Biotechnologies · IMA402 T Cell-Engaging Receptor Molecule (TCER®) in Recurrent and/or Refractory Solid Tumors NCT05958121
Phase 2 · Immunovant · A Study to Evaluate the Efficacy, Safety, and Tolerability of IMVT-1402 in Adult Participants With Active, Difficult to Treat Rheumatoid Arthritis NCT06754462
Not applicable · Insightec · A Prospective, Randomized, Controlled Trial to Test Safety and Effectiveness of Unilateral Exablate MR-guided Focused Ultrasound Subthalamotomy in Patients With Early-Stage Parkinson's Disease NCT06584383
Phase 1/Phase 2 · Iovance Biotherapeutics · A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer NCT05361174
Phase 1 · K36 Therapeutics · A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001) NCT07103018
Phase 2/Phase 3 · Kardigan · A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy NCT07210723
Phase 1/Phase 2 · Kenai Therapeutics · A Study to Assess Safety and Efficacy of Surgical Implant of RNDP-001 in Patients With Idiopathic Parkinson's Disease NCT07106021
Phase 2/Phase 3 · Kyverna Therapeutics · KYSA-6: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, in Patients With Generalized Myasthenia Gravis NCT06193889
Phase not stated · Lexeo Therapeutics · Clinical Course Of Disease In Participants With FA-CM NCT06865482
Phase 1/Phase 2 · Marengo Therapeutics · A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors NCT05592626
Phase 4 · Meitheal Pharmaceuticals · Evaluation of the Excretion of Fosfomycin Into Breast Milk Following a Single Intravenous Dose of ZTI-01 (6 g) in Healthy Lactating Women NCT07618299
Phase 1 · ModeX Therapeutics · A Study Evaluating MDX2301 in Healthy Adults and Adults at Higher Risk for Severe COVID-19. NCT07445971
Not applicable · Nanochon, Inc. · Nanochon Chondrograft First in Human (FIH) Early Feasibility Study (EFS) - Panama NCT07542184
Phase 2 · Navigator Medicines · A Study to Assess NAV-240 in Adult Participants With Hidradenitis Suppurativa NCT07384975
Not applicable · New World Medical · Clinical Trial to Evaluate the Safety and Effectiveness of a Canaloplasty Device in Subjects With Open-Angle Glaucoma NCT05696561
Phase 2 · Novelmed Therapeutics Inc · Study of NM8074 in Soliris-Treated Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) NCT05731050
Phase 3 · Otsuka · Trial of Brexpiprazole Once-weekly (QW) Formulation in Patients With Acute Schizophrenia NCT05325645
Phase 1 · Pasithea Therapeutics · PAS-004 in Adults Who Have Neurofibromatosis Type 1 With Plexiform Neurofibromas NCT06961565
Phase not stated · REGENXBIO Inc. · Long Term Follow-Up for RGX-111 NCT06103487
Phase not stated · Santen · PRESERFLO™ MicroShunt XI Observational PMCF Study With no Control Group NCT07235592
Not applicable · Sonablate · Safety of the Sonablate HIFU System for the Ablation of Incompetent Veins of the Periphery NCT06642051
Phase 2 · Syndeio Biosciences · Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder NCT06547489
Not applicable · Teleflex Medical · Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions NCT06779630
Phase 1/Phase 2 · Trace Neuroscience · FUNCtion ALS: Aiming to Restore UNC13A Function in People Living With ALS NCT07674667
Phase 2 · Trevi Therapeutics · The Effect of Nalbuphine Extended-Release (NAL ER) on Cough in Participants With Refractory Chronic Cough (RCC) NCT07671924
Phase 1 · TriSalus Life Sciences · Pressure Enabled Intrapancreatic Delivery of SD-101 With Checkpoint Blockade for Locally Advanced Pancreatic Adenocarcinoma NCT05607953
Phase 3 · Ultragenyx Pharmaceutical · Clinical Study of DTX301 AAV-Mediated Gene Transfer for Ornithine Transcarbamylase (OTC) Deficiency NCT05345171
Phase 2 · Upstream Bio · A Long-Term Safety and Efficacy Study of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALOUR) NCT06966479
Phase 3 · X4 Pharmaceuticals · A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections NCT06056297
Not applicable · Zimmer Biomet · Zimmer Trabecular Metal Total Ankle PMCF NCT02038140
Not applicable · ZKR Orthopedics · Evaluation of the Patellar LIFT System for Subjects With Patellofemoral Cartilage Degeneration NCT06423300
Phase 2 · Aeovian Pharmaceuticals · Safety and Efficacy of AV078 in Participants With Tuberous Sclerosis Complex (TSC) Refractory Epilepsy (RESTOR-1) NCT07680322
Phase 2 · Boehringer Ingelheim · A Study to Test Whether BI 1815368 Helps People With an Eye Condition Called Diabetic Macular Edema NCT06962839
Phase 2 · Daiichi Sankyo · A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors NCT06172478
Phase 2 · Wockhardt · This is a Phase 2 Study to Evaluate the Efficacy, Safety, and Tolerability of Intravenous Ertapenem-zidebactam Versus Ceftazidime-Avibactam in the Treatment of Hospitalized Adult Patients With Complic NCT07840105
Phase not stated · Biogen · Pediatric Spinal Muscular Atrophy (SMA) China Registry NCT05042921
Phase 1 · ImmunityBio · IBRX-042 In Participants With HPV-Associated Tumors NCT05976828
Phase 2 · Appello Pharmaceuticals · A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations NCT07432958
Phase 2 · Novartis · A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation NCT07217067
Phase 1 · Novo Nordisk A/S · A Research Study Looking Into How a High Dose of s.c. Semaglutide Works With Emptying of the Stomach in People With Excess Body Weight NCT07845578
Phase 1 · Novo Nordisk A/S · A Study to See How Safe a New Medicine (NNC0642-1895) is in Healthy People NCT07829406
Not applicable · SRI International · Thermoregulatory Physiology of Menopausal Hot Flashes NCT07824648
Phase 1/Phase 2 · Arrowhead Pharmaceuticals · A First-In-Human Study of ARO-INHBE in Adults With Obesity With and Without Type 2 Diabetes Mellitus NCT06700538
Phase 3 · Paradigm Therapeutics · An Open Label Extension Safety Study to Evaluate SD-101 in Epidermolysis Bullosa NCT07482813
Phase 2 · Sanofi · A Study to Investigate Efficacy and Safety With SAR445399 in Adult Participants With Moderate to Severe Hidradenitis Suppurativa NCT07225569
Phase 2 · Incyte · Study to Assess the Safety and Tolerability of Tafasitamab in Adult Participants With Primary Autoimmune Blood Cell Disorders NCT07104565
Phase 3 · Amgen · Phase 3 Trial of Tarlatamab (SC vs IV) in Extensive-Stage Small Cell Lung Cancer After Platinum Based First-line Chemotherapy (ES-SCLC) NCT07778316
Phase 3 · Biogen · A Study to Learn About the Effect of Higher Doses of Nusinersen (BIIB058) Given as Injections to Participants With Spinal Muscular Atrophy (SMA) Who Were Previously Treated With Risdiplam (ASCEND) NCT05067790
Phase 2/Phase 3 · Merck & Co., Inc. · A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003) NCT05139017
Phase 3 · Incyte · A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease NCT06585774
Phase 2 · Acurx Pharmaceuticals · ACX-362E [Ibezapolstat] for Oral Treatment of Recurrent Clostridioides Difficile Infection NCT07513285
Phase not stated · Aclarion · Examination of Nociscan Impact on Low Back Pain Surgical Outcomes NCT06661850
Phase 1 · Alnylam Pharmaceuticals · A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma NCT06600321
Phase 2 · Altimmune · RESTORE TRIAL: Study of the Efficacy and Safety of Pemvidutide in the Treatment of Alcohol-Associated Liver Disease (ALD) NCT07009860
Not applicable · Apreo Health · Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3 NCT06891755
Phase not stated · Bausch + Lomb · IC-8 Apthera IOL New Enrollment Post Approval Study NCT06060041
Phase not stated · Bayer AG · An Observational Study Called FINE-REAL Korea to Learn More About the Use of the Drug Finerenone in People With Chronic Kidney Disease and Type 2 Diabetes in a Routine Medical Care Setting in South Ko NCT07232537
Phase 1 · Biogen · A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants With Spinal Muscular Atrophy (PIERRE-PK) NCT06555419
Phase 4 · BioMarin Pharmaceutical · Immune Modulation During Palynziq® Treatment in Adults (IMPALA) NCT07477691
Phase 1 · BioTheryX · Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of BTX-9341 in Advanced and/or Metastatic Breast Cancer NCT06515470
Phase 1 · Cullinan Therapeutics Inc. · A Phase 1b Study of CLN-049 in Combination With Azacitidine and Venetoclax in AML Patients NCT07722767
Phase 1 · Fate Therapeutics · A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease NCT06308978
Phase 1/Phase 2 · Genmab · Safety and Efficacy Trial of Epcoritamab Combinations in Subjects With B-cell Non-Hodgkin Lymphoma (B-NHL) NCT04663347
Phase 3 · Grifols · A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitryp NCT07555483
Phase 2 · Incyte · An Open-Label Study to Enable Continued Treatment Access for Subjects Previously Enrolled in Studies of Ruxolitinib NCT02955940
Phase not stated · Ipsen · Study of Cabozantinib as Monotherapy or in Combination With Nivolumab in Patients With Advanced or Metastatic Renal Cell Carcinoma Under Real-life Clinical Setting in 1st Line Treatment. NCT03647878
Phase 1 · KaliVir Immunotherapeutics · A Study of VET3-TGI in Patients With Solid Tumors NCT06444815
Phase 2 · MAIA Biotechnology · THIO Sequenced With Cemiplimab in Advanced NSCLC NCT05208944
Phase 1 · Moderna · A Study to Investigate the Safety, Reactogenicity, and Immunogenicity of mRNA-1469 Vaccine to Prevent Ebola-Bundibugyo Virus Disease in Healthy Adult Participants NCT07737717
Phase 1 · OncoC4 · Safety, Pharmacokinetics (PK), and Efficacy of ONC 841 in Advanced Solid Tumors NCT06352359
Phase not stated · Otsuka · REXULTI Drug General Use-results Survey (Excessive Motor Activity or Physically/Verbally Aggressive Behavior Due to Rapid Changes in Mood, Irritability, and/or Outbursts Associated With Dementia Due t NCT06875986
Phase 2 · PTC Therapeutics · Study of PTC844 in Participants With Active Rheumatoid Arthritis NCT07779616
Phase 2 · Rein Therapeutics · A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary Fibrosis NCT06968845
Phase 1/Phase 2 · Remix Therapeutics · Study of REM-422 in Patients With Recurrent, Metastatic, or Unresectable Adenoid Cystic Carcinoma NCT06118086
Early phase 1 · Sumitomo Pharma America, Inc. · Study of DSP-0390 in Patients With Recurrent High-Grade Glioma NCT05023551
Phase not stated · Takeda · A Study of Secondary Immunodeficiencies in Adults With Blood Cancers in Kazakhstan Who Have a Weakened Immune System (K-SIDE Study) NCT07868107
Phase 3 · Vanda Pharmaceuticals · Motion Delos: An Open Label Safety and Efficacy of Tradipitant in Participants Affected by Motion Sickness NCT06138613
Phase 3 · Vertex Pharmaceuticals Incorporated · Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis Participants 12 Months of Age and Older NCT06460506

Oct 2027 (estimated) · 66 trials

Phase not stated · Applied Biologics · Evaluating the Durability of Closure for Diabetic Foot Ulcers Following a Randomized, Controlled, Modified Platform Trial. NCT07360418
Phase 1 · Aptevo Therapeutics · APVO436 Phase 1b/2 Study in Patients With Newly Diagnosed AML NCT06634394
Not applicable · Avisi · Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma NCT07220876
Not applicable · Biocomposites · Antibiotic Device for Osteomyelitis of the Extremities Pivotal Trial - Genex With Gentamicin. NCT07270380
Phase 2 · Climb Bio · A Phase 2 Study of Budoprutug in Subjects With Primary Membranous Nephropathy NCT07096843
Not applicable · Cochlear · A Pivotal Study to Evaluate the Clinical Benefit, Performance and Safety of a Totally Implantable Cochlear Implant (TICI) System in Adults NCT07287124
Not applicable · Cochlear · Investigating the Acceptance and Performance of Low Energy Audio Streaming in Nucleus 8 and Kanso 3 Sound Processors by Experienced Cochlear Implant Users NCT07262827
Phase 2 · Daré Bioscience · A Study of the Preliminary Efficacy of DARE-HPV to Treat High-risk Persistent Human Papillomavirus (hrHPV) NCT07601074
Phase 2 · Endevica Bio · Safely Optimizing Body Weight With Mifomelatide (TCMCB07) in Patients With Newly Diagnosed Colorectal Cancer (CRC) or Pancreatic Ductal Adenocarcinoma (PDAC) Undergoing Chemotherapy NCT06937177
Phase 2 · Evommune · Study of EVO756 in Adults With Migraine NCT07616128
Phase 2 · Forward Therapeutics · Phase 2 Trial of FT2109 for the Treatment of Psoriatic Arthritis NCT07869134
Phase 1/Phase 2 · Frontier Medicines Corporation · A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors NCT06244771
Not applicable · HeartFlow · REWRITE-CAD Protocol: Risk Evaluation With AI-CPA to Reduce Progression and Improve Lifetime Care for Patients With Known Coronary Artery Disease NCT07834372
Phase 2 · Helsinn · Study With IV NEPA (Fosnetupitant/Palonosetron) for the Prevention of Chemotherapy-induced Nausea and Vomiting in Paediatric Cancer Patients Undergoing Highly Emetogenic Chemotherapy (HEC) NCT06904235
Phase 1 · ImmunityBio · Study for Participants With Relapsed/Refractory Non-Hodgkin Lymphoma NCT06334991
Phase 1/Phase 2 · ImmunoGenesis · A Study of Evofosfamide in Combination with Zalifrelimab and Balstilimab NCT06782555
Phase 3 · Kallyope · A Study to Assess the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine NCT07816367
Phase 2 · Kumquat Biosciences · KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting (SynerGIST-1st Line) NCT07406633
Phase 2 · Mirum Pharmaceuticals · Study of MRM-3379 in Male Participants With Fragile X Syndrome (BLOOM) NCT07209462
Not applicable · Nevro · PDN Post Market, Multicenter, Prospective, Global Clinical Study NCT05301816
Phase 2 · Novelmed Therapeutics Inc · Study of NM8074 in Patients with Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis (AAV) NCT06226662
Phase 2 · Opko Health · Pharmacokinetics, Pharmacodynamics, Safety and Tolerability Evaluation of CTAP101 Extended-release Capsules in Pediatric Participants NCT07494045
Phase 2 · Oruka Therapeutics · Dose Ranging Study of ORKA-002 in Patients With Moderate-to-Severe Plaque Psoriasis NCT07474792
Phase not stated · Pacific Edge · Longitudinal Bladder Cancer Study for Tumour Recurrence NCT05080998
Not applicable · Pacific Edge · Study to Assess the Impact of the Urine Test Cxbladder Triage Plus on the Number of Cystoscopies Performed on Patients With Invisible Blood in Their Urine. NCT06394869
Phase 2 · Palisade Bio · A Trial to Investigate PALI-2108 Versus Placebo in Participants With Moderately to Severely Active Ulcerative Colitis NCT07845487
Not applicable · Shockwave Medical · Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of Calcified Carotid Arteries Prior to Trans-Carotid Stenting (SKYWARD Trans-Carotid IDE [Inve NCT07062471
Phase 1/Phase 2 · Sirius Therapeutics · A Study of SRSD384 in Overweight or Obese Participants NCT07557355
Phase 2 · Spyre Therapeutics · A Study of SPY072 in Adults With Moderate to Severe Hidradenitis Suppurativa (The SKYLIGHT Trial) NCT07766005
Not applicable · Starlight Cardiovascular · Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study NCT07114718
Phase 2 · Tarsus Pharmaceuticals · A Study to Evaluate Safety and Efficacy of TP-05 in Healthy Participants With Tick Exposure NCT07562087
Phase 2 · TORL BioTherapeutics · CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer. NCT06690775
Phase 2 · Upstream Bio · A Study to Assess the Efficacy and Safety of Verekitug in Participants With COPD NCT06981078
Phase 2 · Veru · Proof-of-Concept Study Evaluating Total Body Weight, Physical Function & Safety of Enobosarm in Patients Treated With GLP-1 Receptor Agonist, for Weight Loss NCT07446998
Not applicable · Vivex Biologics · Clinical Trial Evaluating the Safety and Efficacy of Nucleus Pulposus Allograft in Participants With Degenerative Disc Disease NCT06778447
Phase 2 · Vogenx · Effect of Mizagliflozin on Hypoglycemia in Patients With Post-Bariatric Hypoglycemia NCT07760961
Phase 2 · Cellsight Technologies, Inc. · Imaging Immune Activation in COVID-19 NCT04815096
Phase 4 · Intrinsic Therapeutics · Return to Activity After Surgery for Lumbar Disc Herniation NCT07667348
Phase not stated · Novo Nordisk A/S · Adverse Event Data Collection From External Registries on Nonacog Beta Pegol NCT03690336
Phase not stated · Smith and Nephew · Safety and Performance Using Legion™ CR Oxinium and CoCr Femoral Implants Combined With Legion™/Genesis™ II XLPE High Flex Tibial Inserts NCT03687593
Phase 2 · Novo Nordisk A/S · A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes NCT07668388
Phase 1 · AusperBio · Study of AHB-171 in Chronic Hepatitis B Participants NCT07617194
Phase 1 · Boehringer Ingelheim · DAREON™-7: A Study to Test How Well Different Doses of BI 764532 in Addition to Chemotherapy Are Tolerated by People With Advanced Neuroendocrine Cancers NCT06132113
Not applicable · Edwards Lifesciences · The ENCIRCLE Trial NCT04153292
Phase 2 · Alexion Pharmaceuticals, Inc. · Phase 2 Study of ALXN2030 in Patients With Antibody-Mediated Rejection After Kidney Transplantation NCT06744647
Phase 2 · Alexion Pharmaceuticals, Inc. · Safety and Efficacy of Tarperprumig in Adult Participants With Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis NCT07160608
Phase 1 · Novo Nordisk A/S · A Research Study on How NNC0638-0355, a New Medicine, Works in People Living With Overweight or Obesity NCT06577766
Phase 2 · Takeda · A Study of Zasocitinib in Adults With Nonsegmental Vitiligo NCT07108283
Phase 1/Phase 2 · Sanofi · A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration NCT07215234
Phase 1 · Proniras · Study to Assess the Use of Tezampanel for Opioid Withdrawal Syndrome in Treatment-Seeking Patients With Opioid Use Disorder NCT06538558
Phase not stated · Incyte · Observational Study for Patients at Risk for Chronic Graft-Versus-Host Disease NCT05919511
Phase 3 · Phathom Pharmaceuticals · A Study to Evaluate the Efficacy and Safety of Vonoprazan 10 mg Compared to Placebo for Relief of Episodic Heartburn in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease Throug NCT07752407
Phase 3 · Throne Biotechnologies · Clinical Application of Stem Cell Educator Therapy in Type 1 Diabetes NCT04011020
Phase 1 · Hinge Bio, Inc. · A Phase 1 Study of HB2198 in Participants With Moderately to Severely Active Systemic Lupus Erythematosus (SLE) NCT07491900
Phase 1 · Stemline Therapeutics · A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer NCT06638307
Phase 3 · Bayer AG · A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the NCT06452277
Phase 2 · Takeda · A Study of Rusfertide in Japanese Adults With Polycythemia Vera NCT07648030
Phase 1 · Alpheus Medical · TMZ + RT + 5-ALA + LIDU SDT System for Newly Diagnosed Butterfly Glioma NCT07862647
Not applicable · Edwards Lifesciences · Autus Valve Continued Access Study (CAS) NCT07466745
Phase 1 · Flare Therapeutics · A Study of FX-909 in Patients With Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma NCT05929235
Phase 2 · Puma Biotechnology · A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer NCT06095505
Phase 1 · Bicara Therapeutics · Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors NCT04429542
Phase 3 · Breathe Biologics · To Evaluate the Safety and Potential Therapeutic Activity of JadiCell™, an Investigational Umbilical Cord-Derived Mesenchymal Stem Cell Therapy, in Patients Diagnosed With Acute Respiratory Distress S NCT07479043
Phase not stated · Ipsen · Study of Cabozantinib in Participants With Neuroendocrine Tumors Who Have Already Received Prior Treatment NCT07314164
Phase 2 · Ipsen · A Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in Adults NCT06625060
Phase not stated · Novo Nordisk A/S · WEgovy Real World Assessment of Weight Loss in Korea NCT07280221

Nov 2027 (estimated) · 26 trials

Phase 2 · Alto Neuroscience, Inc. · ALTO-207 in Adults With Treatment-resistant Depression (TRD) NCT07553637
Phase 2 · Angitia Biopharmaceuticals · Osteogenesis Imperfecta Trial of AGA2115 for ADUlts With COL1A1 and/or COL1A2 GeNetic Variations (IDUN) NCT07062588
Phase 1/Phase 2 · BioNTech US Inc. · A First-in-human, Dose Escalation and Indication Expansion Study of BNT3212 as Monotherapy or in Combination With BNT327 in Adults With Advanced Solid Tumors NCT07147348
Phase 1/Phase 2 · Calico · An Open-Label Exploratory Study of Fosigotifator in Participants With Vanishing White Matter Disease NCT05757141
Phase 2 · Cartesian Therapeutics Inc. · Descartes-08 in Autoantibody Myositis NCT07391605
Not applicable · Cochlear · A Study to Explore Improved Features and a Simplified Treatment Approach for a Totally Implantable Cochlear Implant (TICI) Research System in Adults With Severe Hearing Loss NCT06642935
Phase 3 · Corvus Pharmaceuticals · Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymp NCT06561048
Phase 2 · Curis · A Study of Emavusertib + An Approved Bruton Tyrosine Kinase Inhibitor (BTKi) in Participants With Chronic Lymphocytic Leukemia (CLL) and Other B-cell Malignancies NCT07271667
Phase 1 · Daré Bioscience · Comparing the Pharmacokinetics of a Progesterone Ring Versus a Progesterone Vaginal Insert NCT06668896
Phase 1/Phase 2 · Dynavax Technologies Corporation · Safety and Immunogenicity of an Investigational Herpes Zoster Vaccine (Z-1018) Compared to Shingrix® in Healthy Adults 50 Years of Age and Over NCT06569823
Phase 1 · Exelixis · A Study of XB371 Administered in Participants With Locally Advanced or Metastatic Solid Tumors NCT07123103
Not applicable · Inari Medical · The PERSEVERE Study NCT06588634
Phase 4 · Madrigal Pharmaceuticals · Rezdiffra® With Concomitant Therapies Commonly Used to Treat Comorbidities in Adults With MASH and F2-F3 Fibrosis NCT07848191
Phase 1 · Madrigal Pharmaceuticals · Resmetirom in Patients With MASH and HFpEF NCT07830758
Phase 2 · MapLight Therapeutics · ML-004 Open-Label Extension Study in Adults and Adolescents With Autism Spectrum Disorders (ASD) NCT05889273
Phase 2 · Marea Therapeutics · Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol NCT07028749
Phase 1 · MOMA Therapeutics · Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors NCT06974110
Phase 2 · Novelmed Therapeutics Inc · Study of NM8074 in Patients with Dermatomyositis (DM) NCT06887738
Phase 1 · Parvus Therapeutics · A Phase 1 Study of PVT401 in Healthy Subjects NCT07423000
Phase 2 · Relmada Therapeutics · A Study to Evaluate the Safety and Efficacy of NDV-01 in Participants With NMIBC NCT06663137
Phase 1 · Schrodinger · Study of SGR-1505 in Mature B-Cell Neoplasms NCT05544019
Phase not stated · SI-BONE · Pelvic Fixation and Fusion During Multilevel Spinal Surgery NCT05640908
Not applicable · Supira Medical · Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI) NCT07296744
Phase 3 · United Therapeutics · Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF) NCT05943535
Phase 3 · Vanda Pharmaceuticals · Evaluating the Effects of Tasimelteon vs. Placebo in Treating Pediatric Insomnia NCT06953869
Phase 3 · Vanda Pharmaceuticals · Randomized Withdrawal Study in Patients With Schizophrenia NCT06961968

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