COMPANY
Smith and Nephew
FDA-cleared device company Past trials only
We are a portfolio medical technology company focused on the repair, regeneration and replacement of soft and hard tissue. From company website Source · Oct 12, 2026
Hiring
| Title | Location (from posting) | Employer posted | First seen |
|---|---|---|---|
| Sr. Associate, Global Customer Care, International Order Management | IND - NonGBS-Pune-Kharadi | Oct 22, 2026 | Oct 16, 2026 |
| Interim Assistant Company Secretary | UK - Watford | Oct 22, 2026 | Oct 22, 2026 |
| Territory Manager AWM Wound Care | POL - Field | Oct 22, 2026 | Oct 22, 2026 |
| Territory Manager, Complex Wounds, Hospital - QLD | AUS - Brisbane | Oct 22, 2026 | Oct 22, 2026 |
| Business Development Executive, Community - NZ | NZL - Auckland | Oct 22, 2026 | Oct 22, 2026 |
Trial and FDA signals
- Device approval + hiring FDA De Novo device grant for TESSA Spatial Surgery System (DEN250037, Jul 6, 2026); 249 manufacturing/quality or commercial roles open. FDA DEN250037 (Jul 6, 2026)
Evidence (1 event)
- Jul 6, 2026 · FDA DEN250037
openFDA device/510k: k_number=DEN250037; applicant='Smith & Nephew, Inc.'; decision_code=DENG; decision_date=2026-07-06; device_name='TESSA Spatial Surgery System; INTELLIO Tablet (72205455)'
- Jul 6, 2026 · FDA DEN250037
Timeline
- Trial start Not phased (device or behavioral study): Sacrum Pressure Injury Prevention Study Using ALLEVYN◊ Complete Care in Adults at Risk of Developing Hospital-acquired Pressure Injuries in Critical Care Units source ↗
- Board tracked Radar started tracking this company’s job board (404 open jobs at last check). source ↗
- Trial start —: Knee Cartilage Repair Registry source ↗
- FDA FDA 510(k) clearance: LANDMARK Total Knee System — K261462, Sep 8, 2026. Applicant at approval: Smith & Nephew, Inc. source ↗
- FDA FDA 510(k) clearance: Q-FIX KNOTLESS All-Suture Anchor, 2.8mm, with one black knotless and one blue MINITAPE suture (72205981); Q-FIX KNOTLESS All-Suture Anchor, 2.8mm, with one blue knotless and one source ↗
- FDA FDA De Novo grant: TESSA Spatial Surgery System; INTELLIO Tablet (72205455) — DEN250037, Jul 6, 2026. Applicant at approval: Smith & Nephew, Inc. source ↗
- FDA FDA 510(k) clearance: AETOS Shoulder System - CONCELOC Glenoids — K254084, Apr 6, 2026. Applicant at approval: Smith & Nephew, Inc. source ↗
- FDA FDA 510(k) clearance: AETOS Shoulder System Meta Humeral Prosthesis Size 0 — K252416, Oct 29, 2025. Applicant at approval: Smith & Nephew, Inc. source ↗
- FDA FDA 510(k) clearance: AETOS Shoulder System Stemless Humeral Prosthesis — K252129, Oct 3, 2025. Applicant at approval: Smith & Nephew, Inc. source ↗
- Trial start —: A Multi-Center Study Assessing the Safety and Efficacy of the LEGION Medial Stabilized (MS) Insert in Patients Undergoing a Total Knee Arthroplasty (TKA) source ↗
- Trial start Not phased (device or behavioral study): Post-Market Clinical Study to Evaluate the Safety and Effectiveness of REFLEX ULTRA 45 for Coblation Inferior Turbinate Reduction in China source ↗
- FDA FDA 510(k) clearance: BIORAPTOR 2.3 PK Suture Anchor w/ ULTRABRAID (#2) Suture (cobraid blue); BIORAPTOR 2.3 PK Suture Anchor w/ ULTRABRAID (#2) Suture (cobraid black); BIORAPTOR 2.3 PK Suture Anchor source ↗
- FDA FDA 510(k) clearance: TRIGEN Stable Lock Nut & Washer — K243608, Jun 12, 2025. Applicant at approval: Smith & Nephew, Inc. source ↗
- Trial start —: A Post Approval Multicenter 10 Year Follow-up Observational Trial of Marketed Product - MP01 vs. Surgical Standard of Care (SSOC) Used for the Treatment of Joint Surface Lesions of the Knee source ↗
- FDA FDA 510(k) clearance: LEGION Total Knee System — K250677, Apr 2, 2025. Applicant at approval: Smith & Nephew, Inc. source ↗
- FDA FDA 510(k) clearance: CATALYSTEM Femoral Stems — K250571, Mar 28, 2025. Applicant at approval: Smith & Nephew, Inc. source ↗
- Trial start Not phased (device or behavioral study): Human Participant Study of a Prototype Multilayer Foam Dressing on Intact Skin. source ↗
- FDA FDA 510(k) clearance: TRIGEN META-TAN Trochanteric Antegrade Nail — K243364, Dec 9, 2024. Applicant at approval: Smith & Nephew, Inc. source ↗
- FDA FDA 510(k) clearance: AETOS Shoulder System Stemless Humeral Prosthesis — K240716, Nov 20, 2024. Applicant at approval: Smith & Nephew, Inc. source ↗
- FDA FDA 510(k) clearance: JOURNEY II Unicompartmental Knee System (JOURNEY II UK) — K242711, Oct 30, 2024. Applicant at approval: Smith & Nephew, Inc. source ↗
- Trial start Not phased (device or behavioral study): Human Participant Study of Prototype Non-medicated Multilayer Foam Dressings on Intact Skin source ↗
- FDA FDA 510(k) clearance: Anthology Hip Stems; CPCS Hip Stems; Femoral Heads; R3 Acetabular Liners; Spectron Hip Stems; Synergy Hip Stems — K240783, Oct 21, 2024. Applicant at approval: Smith & Nephew, Inc. source ↗
- Trial start —: A Multi-Centre Study in Patients Undergoing Total Hip Arthroplasty With the Smith+Nephew CATALYSTEM™ Primary Hip System source ↗
- Trial start —: A Clinical Study on New Negative Pressure Wound Therapy Dressing in the Management of Chronic & Acute Wounds source ↗
- Trial start Not phased (device or behavioral study): PICO Venous Leg Ulcers (VLU) Reimbursement Study source ↗
Upcoming milestones
- Feb 5, 2027 (ESTIMATED) · · A Post Approval Multicenter 10 Year Follow-up Observational Trial of Marketed Product - MP01 vs. Surgical Standard of Care (SSOC) Used for the Treatment of Joint Surface Lesions of the Knee · NCT06916728
- Apr 15, 2027 (ESTIMATED) · Not phased · Use of the REGENETEN™ Bioinductive Implant System in High Grade Partial-thickness Tears · NCT05444465
- Oct 1, 2027 (ESTIMATED) · · Safety and Performance Using Legion™ CR Oxinium and CoCr Femoral Implants Combined With Legion™/Genesis™ II XLPE High Flex Tibial Inserts · NCT03687593
- 2027-12 (ESTIMATED) · · A Multi-Centre Study in Patients Undergoing Total Hip Arthroplasty With the Smith+Nephew CATALYSTEM™ Primary Hip System · NCT06564636
- Dec 31, 2027 (ESTIMATED) · · LEGION Hinge Safety and Efficacy Study · NCT02445443
- 2028-06 (ESTIMATED) · · JOURNEY™ II CR Total Knee System · NCT02440672
- Oct 24, 2028 (ESTIMATED) · Not phased · Sacrum Pressure Injury Prevention Study Using ALLEVYN◊ Complete Care in Adults at Risk of Developing Hospital-acquired Pressure Injuries in Critical Care Units · NCT07849387
- Apr 30, 2029 (ESTIMATED) · · Ten Year Implant Survivorship of the ANTHEM™ PS Total Knee System · NCT03078543
Open jobs 403
| Title | Location (from posting, not HQ) | Employer posted | First seen | Level |
|---|---|---|---|---|
| Sr. Associate, Global Customer Care, International Order Management | IND - NonGBS-Pune-Kharadi | Oct 22, 2026 | Oct 16, 2026 | Not stated |
| Interim Assistant Company Secretary | UK - Watford | Oct 22, 2026 | Oct 22, 2026 | Not stated |
| Territory Manager AWM Wound Care | POL - Field | Oct 22, 2026 | Oct 22, 2026 | Not stated |
| Territory Manager, Complex Wounds, Hospital - QLD | AUS - Brisbane | Oct 22, 2026 | Oct 22, 2026 | Not stated |
| Business Development Executive, Community - NZ | NZL - Auckland | Oct 22, 2026 | Oct 22, 2026 | Not stated |
| Loan Set Controller Graduate | ZAF - Johannesburg | Oct 21, 2026 | Oct 9, 2026 | Entry |
| Industrial Plumber (US - Memphis) | Memphis, TN | Oct 21, 2026 | Oct 9, 2026 | Mid |
| Industrial Plumber (US - Memphis) | Memphis, TN | Oct 21, 2026 | Oct 9, 2026 | Mid |
| Spatial Surgery Development Manager (SSDM) | 82 locations, including Dallas TX, US | Oct 21, 2026 | Oct 9, 2026 | Mid |
| Senior Financial Reporting Accountant with German | POL - Wroclaw | Oct 21, 2026 | Oct 13, 2026 | Senior |
| Senior Marketing Manager | UAE - DUBAI | Oct 21, 2026 | Oct 16, 2026 | Not stated |
| Quality Engineer 2 | US - Maple Plain | Oct 21, 2026 | Oct 22, 2026 | Not stated |
| Senior Advanced Manufacturing Engineer | US - Maple Plain | Oct 21, 2026 | Oct 22, 2026 | Not stated |
| Design Quality Engineer | Austin, TX | Oct 21, 2026 | Oct 22, 2026 | Not stated |
| IT Support Specialist - Hybrid (Pittsburgh, PA) | Pittsburgh, PA | Oct 21, 2026 | Oct 22, 2026 | Not stated |
| Packaging Process Engineer | Memphis, TN | Oct 21, 2026 | Oct 22, 2026 | Not stated |
| Principal Product Security Engineer | 2 locations (listed on the posting) | Oct 21, 2026 | Oct 9, 2026 | Not stated |
| Intern Computer Vision Software Engineering | Andover, MA | Oct 21, 2026 | Oct 22, 2026 | Not stated |
| Sports Medicine Territory Manager (Washington, DC) | US - Washington DC | Oct 21, 2026 | Oct 22, 2026 | Not stated |
| Intern Biologics R&D | US - Fort Worth, TX | Oct 21, 2026 | Oct 22, 2026 | Not stated |
| Co-op Research & Development | US - Austin Artemis TX | Oct 21, 2026 | Oct 22, 2026 | Not stated |
| Intern Mechanical Engineering | Mansfield, MA | Oct 21, 2026 | Oct 22, 2026 | Not stated |
| Intern Electrical Engineering | Andover, MA | Oct 21, 2026 | Oct 22, 2026 | Not stated |
| Co-Op Electrical Engineering | Andover, MA | Oct 21, 2026 | Oct 22, 2026 | Not stated |
| Intern Systems Engineering | Andover, MA | Oct 21, 2026 | Oct 22, 2026 | Not stated |
| Co-Op Systems Engineering | Andover, MA | Oct 21, 2026 | Oct 22, 2026 | Not stated |
| Intern Embedded Software Engineering | Andover, MA | Oct 21, 2026 | Oct 22, 2026 | Not stated |
| Intern Agentic AI Software Engineering | Andover, MA | Oct 21, 2026 | Oct 22, 2026 | Not stated |
| Senior Regulatory Affairs Specialist | Mansfield, MA | Oct 20, 2026 | Oct 9, 2026 | Senior |
| NPD Materials Specialist | Oklahoma City, OK | Oct 20, 2026 | Oct 16, 2026 | Not stated |
| Machining Operator 1- 2nd shift | Mansfield, MA | Oct 20, 2026 | Oct 22, 2026 | Not stated |
| Associate Sourcing Specialist | CR - Alajuela, Coyol | Oct 20, 2026 | Oct 22, 2026 | Not stated |
| Senior Trade Compliance Specialist | CR - Alajuela, Coyol | Oct 20, 2026 | Oct 22, 2026 | Not stated |
| Director of Sales, ENT | US - Field | Oct 20, 2026 | Oct 22, 2026 | Not stated |
| Product Specialist | UAE - Field | Oct 20, 2026 | Oct 22, 2026 | Not stated |
| Sales Representative (w/m/x) Sportmedizin (Region Sachsen) | 2 locations, including Sachsen, DEU | Oct 20, 2026 | Oct 22, 2026 | Not stated |
| Business Development Executive, Hospital - NZ | NZL - Auckland | Oct 20, 2026 | Oct 22, 2026 | Not stated |
| Commercial Capability Lead ANZ, Cross Franchises | AUS - Sydney | Oct 19, 2026 | Oct 9, 2026 | Senior |
| Regulatory Affairs Manager - Orthopedics | US - Field | Oct 19, 2026 | Oct 9, 2026 | Senior |
| Solution Architect - Enterprise AI | IND - NonGBS-Pune-Kharadi | Oct 19, 2026 | Oct 9, 2026 | Senior |
| Enterprise Architect - Enterprise AI Platform & Governance | IND - NonGBS-Pune-Kharadi | Oct 19, 2026 | Oct 9, 2026 | Senior |
| Health, Safety & Environmental Manager (Oklahoma City, OK) | Oklahoma City, OK | Oct 19, 2026 | Oct 9, 2026 | Senior |
| Sales Representative (w/m/x) Orthopädie (Wien) | 2 locations, including Wien, AUT | Oct 19, 2026 | Oct 9, 2026 | Mid |
| Manufacturing Engineer 1 | Oklahoma City, OK | Oct 19, 2026 | Oct 9, 2026 | Not stated |
| Machine Maintenance Technician III | Memphis, TN | Oct 19, 2026 | Oct 9, 2026 | Mid |
| Sr. Packaging Process Engineer | Memphis, TN | Oct 19, 2026 | Oct 16, 2026 | Not stated |
| Senior Director, Commercial Analytics & Strategy (Fort Worth, TX) | Fort Worth | Oct 19, 2026 | Oct 16, 2026 | Not stated |
| Délégué(e) Médico-Commercial(e) Ville – Nord-Est Île-de-France | FRA - Paris | Oct 19, 2026 | Oct 19, 2026 | Not stated |
| Délégué(e) Médico-Commercial(e) Ville - Sud Île-de-France | FRA - Paris | Oct 19, 2026 | Oct 19, 2026 | Not stated |
| Sales Representative | ESP - Sevilla | Oct 19, 2026 | Oct 19, 2026 | Not stated |
Clinical trials (lead sponsor) Showing 50 of 133
| Record | Title | Phase | Status | Start | Primary completion |
|---|---|---|---|---|---|
| NCT07786207 | Knee Cartilage Repair Registry | Not listed | Recruiting | Sep 23, 2026 | Mar 31, 2034 (estimated) |
| NCT07849387 | Sacrum Pressure Injury Prevention Study Using ALLEVYN◊ Complete Care in Adults at Risk of Developing Hospital-acquired Pressure Injuries in Critical Care Units | Not phased (device or behavioral study) | Not yet recruiting | Oct 30, 2026 | Oct 24, 2028 (estimated) |
| NCT05444465 | Use of the REGENETEN™ Bioinductive Implant System in High Grade Partial-thickness Tears | Not phased (device or behavioral study) | Recruiting | Aug 30, 2022 | Apr 15, 2027 (estimated) |
| NCT04325022 | Safety and Effectiveness Study of OR3O™ Dual Mobility System in THA | Not listed | Active, not recruiting | Jul 27, 2020 | Feb 23, 2026 (actual) |
| NCT05197036 | A Global Clinical Study Investigating the Safety and Effectiveness of Smith and Nephew's Porous Knee System in Patients Who Need a Total Knee Replacement Due to Degenerative Arthritis, Post-traumatic Arthritis or Inflammatory Arthritis | Not listed | Active, not recruiting | Dec 21, 2021 | Jun 11, 2026 (actual) |
| NCT07199738 | A Multi-Center Study Assessing the Safety and Efficacy of the LEGION Medial Stabilized (MS) Insert in Patients Undergoing a Total Knee Arthroplasty (TKA) | Not listed | Recruiting | Sep 25, 2025 | 2036-12 (estimated) |
| NCT06916728 | A Post Approval Multicenter 10 Year Follow-up Observational Trial of Marketed Product - MP01 vs. Surgical Standard of Care (SSOC) Used for the Treatment of Joint Surface Lesions of the Knee | Not listed | Enrolling by invitation | May 5, 2025 | Feb 5, 2027 (estimated) |
| NCT03985839 | Safety and Performance of MICRORAPTOR™ Suture Anchors in Shoulder and Hip | Not listed | Completed | Aug 1, 2019 | Aug 8, 2024 (actual) |
| NCT04849884 | To Evaluate the Performance of the CORI™ KNEE TENSIONER as an Accessory to the CORI™ Surgical System. | Not phased (device or behavioral study) | Completed | Mar 30, 2022 | Jun 4, 2025 (actual) |
| NCT03247023 | Long Term Follow-up of Integra® Cadence™ Total Ankle System in Primary Ankle Joint Replacement | Not listed | Terminated | Sep 18, 2017 | Sep 6, 2023 (actual) |
| NCT02440672 | JOURNEY™ II CR Total Knee System | Not listed | Active, not recruiting | 2015-09 | 2028-06 (estimated) |
| NCT06831448 | Human Participant Study of a Prototype Multilayer Foam Dressing on Intact Skin. | Not phased (device or behavioral study) | Completed | Jan 27, 2025 | Mar 17, 2025 (actual) |
| NCT06857084 | Evaluation Of Outcomes Following Rotator Cuff Repair Using the REGENETEN Bioinductive Implant | Not listed | Recruiting | Oct 1, 2020 | Dec 31, 2029 (estimated) |
| NCT03720782 | Safety and Performance Study of the Legion Porous System in Total Knee Arthroplasty | Not listed | Active, not recruiting | May 22, 2019 | Jan 23, 2031 (estimated) |
| NCT04552119 | Safety of Treatment of Shoulder Repair | Not listed | Completed | Jan 26, 2021 | May 24, 2024 (actual) |
| NCT00611585 | A Safety and Efficacy Study of the Birmingham Hip Resurfacing System | Not listed | Completed | Oct 6, 2006 | May 12, 2025 (actual) |
| NCT06700850 | Human Participant Study of Prototype Non-medicated Multilayer Foam Dressings on Intact Skin | Not phased (device or behavioral study) | Completed | Oct 28, 2024 | Jan 21, 2025 (actual) |
| NCT02353377 | OXINIUM◊ DH Total Hip Arthroplasty Pivotal Study | Not listed | Active, not recruiting | 2015-01 | Sep 21, 2021 (actual) |
| NCT04903106 | Safety and Performance Study of the FAST-FIX FLEX System for Meniscal Repairs and Meniscal Transplantations | Not listed | Completed | Jan 20, 2022 | Nov 26, 2024 (actual) |
| NCT02204228 | TITAN™ Reverse Shoulder System | Not listed | Terminated | 2014-09 | Dec 14, 2023 (actual) |
| NCT06564636 | A Multi-Centre Study in Patients Undergoing Total Hip Arthroplasty With the Smith+Nephew CATALYSTEM™ Primary Hip System | Not listed | Active, not recruiting | Sep 26, 2024 | 2027-12 (estimated) |
| NCT03078543 | Ten Year Implant Survivorship of the ANTHEM™ PS Total Knee System | Not listed | Active, not recruiting | Jun 28, 2017 | Apr 30, 2029 (estimated) |
| NCT04848896 | Study to Evaluate the Safety and Effectiveness of the REAL INTELLIGENCE™ CORI™ in Total Knee Arthroplasty (TKA) Procedure | Not phased (device or behavioral study) | Recruiting | Feb 12, 2022 | Apr 17, 2026 (estimated) |
| NCT03768128 | Safety and Performance of the Journey™ II UNI Unicompartmental Knee System | Not listed | Completed | Aug 10, 2018 | May 19, 2025 (actual) |
| NCT04361487 | Circumferential Compression STITCH Repairs of Complex and Horizontal Cleavage Meniscal Tears | Not listed | Terminated | Nov 13, 2020 | Apr 25, 2024 (actual) |
| NCT03687593 | Safety and Performance Using Legion™ CR Oxinium and CoCr Femoral Implants Combined With Legion™/Genesis™ II XLPE High Flex Tibial Inserts | Not listed | Active, not recruiting | Aug 26, 2018 | Oct 1, 2027 (estimated) |
| NCT02648152 | POLARSTEM Cementless Hip Stem | Not listed | Completed | 2009-03 | 2020-11 (actual) |
| NCT06510777 | PICO Venous Leg Ulcers (VLU) Reimbursement Study | Not phased (device or behavioral study) | Terminated | Dec 29, 2023 | Oct 24, 2025 (actual) |
| NCT07025304 | Post-Market Clinical Study to Evaluate the Safety and Effectiveness of REFLEX ULTRA 45 for Coblation Inferior Turbinate Reduction in China | Not phased (device or behavioral study) | Recruiting | Jul 2, 2025 | Sep 30, 2026 (estimated) |
| NCT02405208 | A Multi-center Outcomes Clinical Study of the PyroTITAN™ HRA Shoulder Implant in Humeral Head Resurfacing | Not listed | Completed | 2010-08 | 2023-09 (actual) |
| NCT02380092 | Post Market Clinical Follow Up of LEGION™ Primary TKS With VERILAST™ | Not listed | Active, not recruiting | 2015-09 | 2029-05 (estimated) |
| NCT03299959 | Agili-C™ Implant Performance Evaluation | Not phased (device or behavioral study) | Completed | Sep 25, 2017 | Nov 14, 2024 (actual) |
| NCT06036212 | Study to Evaluate Patient Outcomes and Safety and Effectiveness of Robotic Assisted Unicompartmental Knee Replacements Versus Conventional Unicompartmental Knee for Subjects With Primary Arthritis of the Knee Joint Involving One (UKA) Compartment (Medial or Lateral) | Not phased (device or behavioral study) | Withdrawn | Nov 21, 2023 | Mar 15, 2027 (estimated) |
| NCT06306716 | A Clinical Study on New Negative Pressure Wound Therapy Dressing in the Management of Chronic & Acute Wounds | Not listed | Terminated | May 30, 2024 | Oct 31, 2025 (actual) |
| NCT04786119 | Study to Evaluate the Safety and Effectiveness of REAL INTELLIGENCE™ CORI™ in Knee Arthroplasty Procedures | Not phased (device or behavioral study) | Completed | Feb 17, 2021 | Oct 27, 2023 (actual) |
| NCT04818840 | Evaluate the Performance of JOURNEY II CR in TKA Populations | Not listed | Terminated | Mar 3, 2022 | Mar 15, 2024 (actual) |
| NCT05234632 | Study to Evaluate the PICO 14 Negative Pressure Wound Therapy System in the Management of Acute and Chronic Wounds | Not listed | Terminated | Sep 22, 2020 | Sep 23, 2022 (actual) |
| NCT04450342 | REGENETEN™ Bioinductive Implant System in Full-thickness Tears | Not phased (device or behavioral study) | Terminated | Dec 7, 2020 | Oct 31, 2023 (actual) |
| NCT03056534 | R3 Delta Ceramic Acetabular System PAS U.S. | Not listed | Completed | Feb 7, 2018 | May 31, 2023 (actual) |
| NCT04012567 | Safety and Effectiveness of BIOSURE RG in Cruciate Ligaments Reconstruction in Chinese | Not phased (device or behavioral study) | Completed | Dec 17, 2019 | Sep 11, 2021 (actual) |
| NCT04797897 | Study to Evaluate the Safety and Effectiveness of REAL INTELLIGENCE™ CORI™ in Unicondylar Knee Arthroplasty (UKA) Procedures | Not phased (device or behavioral study) | Terminated | Feb 12, 2022 | Sep 29, 2023 (actual) |
| NCT01471236 | Evaluation of the Agili-C Biphasic Implant in the Knee Joint | Not phased (device or behavioral study) | Completed | 2011-06 | Nov 19, 2018 (actual) |
| NCT02831244 | Agili-CTM Implant Performance Evaluation in the Treatment of Osteoarthritis of the Great Toe | Not phased (device or behavioral study) | Completed | Aug 10, 2016 | Jun 23, 2019 (actual) |
| NCT02423629 | Agili-C™ Implant Performance Evaluation in the Repair of Cartilage and Osteochondral Defects | Not phased (device or behavioral study) | Completed | 2014-05 | Nov 19, 2019 (actual) |
| NCT03610789 | A Multicenter, Post-Market Clinical Follow-up Study of Subjects With the REDAPT™ System Monolithic Sleeveless/Sleeved Stem and/or Fully Porous Acetabular Shell With XLPE Liner and/or Modular Shell Components Previously Implanted | Not listed | Enrolling by invitation | May 7, 2018 | Jul 1, 2034 (estimated) |
| NCT04102865 | Performance, Safety and Efficacy of NPWT Device | Not phased (device or behavioral study) | Completed | Jul 12, 2019 | Jul 6, 2022 (actual) |
| NCT02154516 | Pilot Study Evaluating the Safety and Efficacy of a New Hard-on-Hard Total Hip Replacement System | Not phased (device or behavioral study) | Completed | Nov 4, 2011 | Oct 18, 2022 (actual) |
| NCT02445443 | LEGION Hinge Safety and Efficacy Study | Not listed | Active, not recruiting | Jun 30, 2015 | Dec 31, 2027 (estimated) |
| NCT03734536 | Treatment of Partial-Thickness Rotator Cuff Tears | Not phased (device or behavioral study) | Terminated | Dec 5, 2018 | Sep 11, 2023 (actual) |
| NCT03142958 | Clinical Evaluation of Integra® Cadence™ Total Ankle System in Primary Ankle Joint Replacement (CADENCE) | Not listed | Suspended | Aug 24, 2017 | Apr 30, 2025 (estimated) |
FDA records (last 2 years)
- FDA 510(k) clearance: LANDMARK Total Knee System — K261462, Sep 8, 2026. Applicant at approval: Smith & Nephew, Inc. source ↗
- FDA 510(k) clearance: Q-FIX KNOTLESS All-Suture Anchor, 2.8mm, with one black knotless and one blue MINITAPE suture (72205981); Q-FIX KNOTLESS All-Suture Anchor, 2.8mm, with one blue knotless and one black MINITAPE suture (72205982) — K261968, Jul 9, 2026. Applicant at approval: Smith & Nephew, Inc. source ↗
- FDA De Novo grant: TESSA Spatial Surgery System; INTELLIO Tablet (72205455) — DEN250037, Jul 6, 2026. Applicant at approval: Smith & Nephew, Inc. source ↗
- FDA 510(k) clearance: AETOS Shoulder System - CONCELOC Glenoids — K254084, Apr 6, 2026. Applicant at approval: Smith & Nephew, Inc. source ↗
- FDA 510(k) clearance: AETOS Shoulder System Meta Humeral Prosthesis Size 0 — K252416, Oct 29, 2025. Applicant at approval: Smith & Nephew, Inc. source ↗
- FDA 510(k) clearance: AETOS Shoulder System Stemless Humeral Prosthesis — K252129, Oct 3, 2025. Applicant at approval: Smith & Nephew, Inc. source ↗
- FDA 510(k) clearance: BIORAPTOR 2.3 PK Suture Anchor w/ ULTRABRAID (#2) Suture (cobraid blue); BIORAPTOR 2.3 PK Suture Anchor w/ ULTRABRAID (#2) Suture (cobraid black); BIORAPTOR 2.3 PK Suture Anchor w/ ULTRABRAID (#2) Suture (white); BIORAPTOR CURVED 2.3 PK Suture Anchor w/ ONE 38 ULTRABRAID (#2) Suture (cobraid black); — K251627, Jun 25, 2025. Applicant at approval: Smith & Nephew, Inc. source ↗
- FDA 510(k) clearance: TRIGEN Stable Lock Nut & Washer — K243608, Jun 12, 2025. Applicant at approval: Smith & Nephew, Inc. source ↗
- FDA 510(k) clearance: LEGION Total Knee System — K250677, Apr 2, 2025. Applicant at approval: Smith & Nephew, Inc. source ↗
- FDA 510(k) clearance: CATALYSTEM Femoral Stems — K250571, Mar 28, 2025. Applicant at approval: Smith & Nephew, Inc. source ↗
- FDA 510(k) clearance: TRIGEN META-TAN Trochanteric Antegrade Nail — K243364, Dec 9, 2024. Applicant at approval: Smith & Nephew, Inc. source ↗
- FDA 510(k) clearance: AETOS Shoulder System Stemless Humeral Prosthesis — K240716, Nov 20, 2024. Applicant at approval: Smith & Nephew, Inc. source ↗
- FDA 510(k) clearance: JOURNEY II Unicompartmental Knee System (JOURNEY II UK) — K242711, Oct 30, 2024. Applicant at approval: Smith & Nephew, Inc. source ↗
- FDA 510(k) clearance: Anthology Hip Stems; CPCS Hip Stems; Femoral Heads; R3 Acetabular Liners; Spectron Hip Stems; Synergy Hip Stems — K240783, Oct 21, 2024. Applicant at approval: Smith & Nephew, Inc. source ↗
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