COMPANY
Madrigal Pharmaceuticals
Hiring
| Title | Location (from posting) | Employer posted | First seen |
|---|---|---|---|
| Regional Sales Director - South Central | 2 locations, including Field, Houston Texas | Oct 21, 2026 | Oct 18, 2026 |
| Director, Regulatory Affairs CMC | PA - Conshohocken - Office | Oct 20, 2026 | Oct 21, 2026 |
| Manager, Biostatistics | PA - Conshohocken - Office | Oct 16, 2026 | Oct 18, 2026 |
| Senior Director, Data Operations & Enablement | 2 locations, including Office, Conshohocken, PA | Oct 16, 2026 | Oct 18, 2026 |
| Associate Director, New Market Introduction and Life Cycle Lead | Zug - Switzerland - Office | Oct 16, 2026 | Oct 18, 2026 |
Trial and FDA signals
- New trial + clinical hiring Started a Phase 2 trial (NCT07763015, actual start Aug 1, 2026) (+1 other new trial); 13 clinical-operations roles open. ClinicalTrials.gov NCT07763015 (Aug 1, 2026)
Evidence (2 events)
- Aug 1, 2026 · ClinicalTrials.gov NCT07763015
leadSponsor.name='Madrigal Pharmaceuticals, Inc.'; phases=['PHASE2']; overallStatus=RECRUITING; startDateStruct={date:2026-08-01,type:ACTUAL}; studyFirstPostDate=2026-08-13; briefTitle='Study of Resmetirom in Children and Adolescents With MASH' - Oct 7, 2026 · ClinicalTrials.gov NCT07848191
leadSponsor.name='Madrigal Pharmaceuticals, Inc.'; phases=['PHASE4']; overallStatus=RECRUITING; startDateStruct={date:2026-10-07,type:ACTUAL}; studyFirstPostDate=2026-09-29; briefTitle='Rezdiffra® With Concomitant Therapies Commonly Used to Treat Comorbidities in Adults With MASH and F2-F3 Fibrosis'
- Aug 1, 2026 · ClinicalTrials.gov NCT07763015
Timeline
- Board tracked Radar started tracking this company’s job board (59 open jobs at last check). source ↗
- Trial start Phase 4: Rezdiffra® With Concomitant Therapies Commonly Used to Treat Comorbidities in Adults With MASH and F2-F3 Fibrosis source ↗
- Trial start Phase 1: Resmetirom in Patients With MASH and HFpEF source ↗
- Trial start Phase 2: Study of Resmetirom in Children and Adolescents With MASH source ↗
- Trial start —: Rezdiffra Pregnancy and Lactation Registry source ↗
- Trial start Phase 2: Study to Evaluate Resmetirom in Post-Liver Transplant Patients With MASH source ↗
- Trial start Phase 1: A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Multiple Oral Doses (6 Days) of 100 mg Resmetirom in Subjects With Severe Renal Impairment and in Matched Healthy Control source ↗
- Trial start 3: A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES) source ↗
- Trial start 3: A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE) source ↗
- Trial start 3: A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Non Alcoholic Fatty Liver Disease Patients source ↗
- Trial start Phase 1: Drug Interaction Study of MGL-3196 With Clopidogrel source ↗
- Trial start 3: A Phase 3 Study to Evaluate the Efficacy and Safety of MGL-3196 (Resmetirom) in Patients With NASH and Fibrosis source ↗
- Trial start Phase 1: Drug Interaction Study of MGL-3196 With Pioglitazone source ↗
- Trial start 1: Phase 1 Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Multiple Oral Doses of MGL-3196 in Subjects With Varying Degrees of Hepatic Impairment and Healthy Matched Control Subjec source ↗
- Trial start Phase 1: Bioavailability Study of MGL-3196 Tablets Compared to Capsules source ↗
- Trial start Phase 1: Radiolabeled Study to Determine the Mass Balance of [14C] MGL-3196 source ↗
- Trial start Phase 2: Study of MGL-3196 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) source ↗
- Trial start 2: Phase 2 Study of MGL-3196 in Patients With Non-Alcoholic Steatohepatitis (NASH) source ↗
- Trial start Phase 1: Drug Interaction Study of MGL-3196 With Atorvastatin source ↗
- Trial start Phase 1: Drug Interaction Study of MGL-3196 With Rosuvastatin and Simvastatin source ↗
- Trial start Phase 1: Ascending Multiple-Dose Study to Evaluate VIA-3196 in Healthy Subjects source ↗
- Trial start Phase 1: Ascending Single-Dose Study to Evaluate VIA-3196 in Healthy Subjects source ↗
Upcoming milestones
- 2026-12 (ESTIMATED) · 3 · A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES) · NCT05500222
- 2027-03 (ESTIMATED) · 3 · A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE) · NCT04951219
- 2027-11 (ESTIMATED) · Phase 4 · Rezdiffra® With Concomitant Therapies Commonly Used to Treat Comorbidities in Adults With MASH and F2-F3 Fibrosis · NCT07848191
- 2027-11 (ESTIMATED) · Phase 1 · Resmetirom in Patients With MASH and HFpEF · NCT07830758
- 2028-01 (ESTIMATED) · 3 · A Phase 3 Study to Evaluate the Efficacy and Safety of MGL-3196 (Resmetirom) in Patients With NASH and Fibrosis · NCT03900429
- 2028-08 (ESTIMATED) · Phase 2 · Study to Evaluate Resmetirom in Post-Liver Transplant Patients With MASH · NCT07335601
- 2029-07 (ESTIMATED) · Phase 2 · Study of Resmetirom in Children and Adolescents With MASH · NCT07763015
- Apr 8, 2030 (ESTIMATED) · · Rezdiffra Pregnancy and Lactation Registry · NCT07541469
Open jobs 58
| Title | Location (from posting, not HQ) | Employer posted | First seen | Level |
|---|---|---|---|---|
| Regional Sales Director - South Central | 2 locations, including Field, Houston Texas | Oct 21, 2026 | Oct 18, 2026 | Not stated |
| Director, Regulatory Affairs CMC | PA - Conshohocken - Office | Oct 20, 2026 | Oct 21, 2026 | Not stated |
| Manager, Biostatistics | PA - Conshohocken - Office | Oct 16, 2026 | Oct 18, 2026 | Not stated |
| Senior Director, Data Operations & Enablement | 2 locations, including Office, Conshohocken, PA | Oct 16, 2026 | Oct 18, 2026 | Not stated |
| Associate Director, New Market Introduction and Life Cycle Lead | Zug - Switzerland - Office | Oct 16, 2026 | Oct 18, 2026 | Not stated |
| Associate Director, Trial Master File Operations | 2 locations, including Office, Conshohocken, PA | Oct 15, 2026 | Oct 6, 2026 | Senior |
| Senior Manager, FP&A – G&A Business Partner | PA - Conshohocken - Office | Oct 15, 2026 | Oct 16, 2026 | Not stated |
| Vice President, Global Medical Lead - MASH | 2 locations, including Office, Conshohocken, PA | Oct 14, 2026 | Oct 15, 2026 | Executive |
| Associate Director, Sourcing Strategy & Procurement | Zug - Switzerland - Office | Oct 13, 2026 | Oct 6, 2026 | Senior |
| Associate Director Drug Product SME | PA - Conshohocken - Office | Oct 13, 2026 | Oct 14, 2026 | Senior |
| Health Systems Regional Scientific Director | Chicago, Illinois - Field | Oct 13, 2026 | Oct 14, 2026 | Senior |
| Health Systems Regional Scientific Director | Denver, Colorado - Field | Oct 13, 2026 | Oct 14, 2026 | Senior |
| Senior Manager, Brand Analytics & Forecasting | PA - Conshohocken - Office | Oct 9, 2026 | Oct 5, 2026 | Senior |
| Health Systems Regional Scientific Director | TX - Texas - Field | Oct 7, 2026 | Oct 5, 2026 | Senior |
| Health Systems Regional Scientific Director | Philadelphia, Pennsylvania - Field | Oct 7, 2026 | Oct 6, 2026 | Senior |
| Health Systems Regional Scientific Director | MA - Massachusetts - Field | Oct 7, 2026 | Oct 6, 2026 | Senior |
| Senior Director, Clinical Practice Liaison Team- East Region | Philadelphia, Pennsylvania - Field | Oct 7, 2026 | Oct 7, 2026 | Senior |
| Head of Market Access, Italy | Milano - Italy - Office | Oct 7, 2026 | Oct 8, 2026 | Executive |
| Senior Director, Global Safety Physician | MA - Waltham - Office | Oct 6, 2026 | Oct 6, 2026 | Senior |
| Director, Drug Product SME | PA - Conshohocken - Office | Oct 6, 2026 | Oct 6, 2026 | Senior |
| Associate Director, Global Scientific Content | 2 locations, including Office, Conshohocken, PA | Oct 2, 2026 | Oct 5, 2026 | Senior |
| Director, Field Execution and Excellence | Remote - US | Oct 1, 2026 | Oct 5, 2026 | Senior |
| Key Account Director - Southwest | OK - Oklahoma - Field | Sep 30, 2026 | Oct 5, 2026 | Senior |
| Key Account Director - Heartland | MO - Missouri - Field | Sep 30, 2026 | Oct 5, 2026 | Senior |
| VP, Scientific IT Business Partner | PA - Conshohocken - Office | Sep 28, 2026 | Oct 5, 2026 | Executive |
| Associate Director, U.S. Tax Operations & Reporting | MA - Waltham - Office | Sep 28, 2026 | Oct 5, 2026 | Senior |
| Senior Biostatistician | PA - Conshohocken - Office | Sep 25, 2026 | Oct 5, 2026 | Senior |
| Clinical Practice Liaison - South Florida/Puerto Rico | Miami, FL | Sep 23, 2026 | Oct 5, 2026 | Mid |
| Senior Director, Regulatory Affairs CMC | 2 locations, including Office, Waltham, MA | Sep 23, 2026 | Oct 5, 2026 | Senior |
| Executive Director, U.S. HCP Marketing | 2 locations, including Office, Conshohocken, PA | Sep 23, 2026 | Oct 5, 2026 | Executive |
| Associate Director, Specialty Pharmacy Operations | 2 locations, including Office, Conshohocken, PA | Sep 23, 2026 | Oct 5, 2026 | Senior |
| Senior Director, Participant Recruitment and Retention | PA - Conshohocken - Office | Sep 23, 2026 | Oct 5, 2026 | Senior |
| Executive Director, Operations Lead | 2 locations, including Office, Conshohocken, PA | Sep 23, 2026 | Oct 5, 2026 | Executive |
| Director, API External Manufacturing Lead | Zug - Switzerland - Office | Sep 23, 2026 | Oct 5, 2026 | Senior |
| Senior Medical Director, Early Clinical Development & Translational Medicine (MD) | 2 locations, including Office, Conshohocken, PA | Sep 23, 2026 | Oct 5, 2026 | Senior |
| Associate Director, Development Quality – OSD | 2 locations, including Office, Conshohocken, PA | Sep 23, 2026 | Oct 5, 2026 | Senior |
| Vice President, Clinical Development Program Leader | PA - Conshohocken - Office | Sep 23, 2026 | Oct 5, 2026 | Executive |
| Associate Director, MSAT API | Zug - Switzerland - Office | Sep 23, 2026 | Oct 5, 2026 | Senior |
| Senior Director, Clinical Operations | 2 locations, including Office, Conshohocken, PA | Sep 23, 2026 | Oct 5, 2026 | Senior |
| Director, Quality – New Product Development Lead | PA - Conshohocken - Office | Sep 23, 2026 | Oct 5, 2026 | Senior |
| Senior Manager, MSAT Product Knowledge Steward | PA - Conshohocken - Office | Sep 23, 2026 | Oct 5, 2026 | Senior |
| Senior Director, Bioanalysis | PA - Conshohocken - Office | Sep 23, 2026 | Oct 5, 2026 | Senior |
| Director, Clinical Pharmacology | PA - Conshohocken - Office | Sep 23, 2026 | Oct 5, 2026 | Senior |
| Thought Leader Liaison- Cleveland/Pittsburgh | OH - Ohio - Field | Sep 23, 2026 | Oct 5, 2026 | Senior |
| Director, Market Access International | Zug - Switzerland - Office | Sep 23, 2026 | Oct 5, 2026 | Senior |
| Associate Director, Manufacturing Technical Project Management (MSAT) | PA - Conshohocken - Office | Sep 23, 2026 | Oct 5, 2026 | Senior |
| Senior Director, Clinical Supply Release | Remote - US | Sep 23, 2026 | Oct 5, 2026 | Senior |
| Thought Leader Liaison - Great Lakes | MI - Michigan - Field | Sep 23, 2026 | Oct 5, 2026 | Senior |
| Access Reimbursement Manager - Puerto Rico | PR - Puerto Rico - Field | Sep 23, 2026 | Oct 5, 2026 | Mid |
| Senior Manager, GCP Quality Assurance | PA - Pennsylvania – Remote | Sep 23, 2026 | Oct 5, 2026 | Senior |
Clinical trials (lead sponsor) 21
| Record | Title | Phase | Status | Start | Primary completion |
|---|---|---|---|---|---|
| NCT07848191 | Rezdiffra® With Concomitant Therapies Commonly Used to Treat Comorbidities in Adults With MASH and F2-F3 Fibrosis | Phase 4 | Not yet recruiting | 2026-09 | 2027-11 (estimated) |
| NCT07830758 | Resmetirom in Patients With MASH and HFpEF | Phase 1 | Not yet recruiting | 2026-09 | 2027-11 (estimated) |
| NCT07763015 | Study of Resmetirom in Children and Adolescents With MASH | Phase 2 | Recruiting | Aug 1, 2026 | 2029-07 (estimated) |
| NCT07335601 | Study to Evaluate Resmetirom in Post-Liver Transplant Patients With MASH | Phase 2 | Recruiting | Dec 29, 2025 | 2028-08 (estimated) |
| NCT05500222 | A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES) | 3 | Active, not recruiting | Aug 26, 2022 | 2026-12 (estimated) |
| NCT03038022 | Study of MGL-3196 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) | Phase 2 | Completed | Feb 23, 2017 | Jan 15, 2018 (actual) |
| NCT03900429 | A Phase 3 Study to Evaluate the Efficacy and Safety of MGL-3196 (Resmetirom) in Patients With NASH and Fibrosis | 3 | Active, not recruiting | Mar 28, 2019 | 2028-01 (estimated) |
| NCT04951219 | A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE) | 3 | Active, not recruiting | Jul 9, 2021 | 2027-03 (estimated) |
| NCT07541469 | Rezdiffra Pregnancy and Lactation Registry | Not listed | Recruiting | Mar 4, 2026 | Apr 8, 2030 (estimated) |
| NCT02912260 | Phase 2 Study of MGL-3196 in Patients With Non-Alcoholic Steatohepatitis (NASH) | 2 | Completed | Oct 18, 2016 | Oct 25, 2017 (actual) |
| NCT06397872 | A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Multiple Oral Doses (6 Days) of 100 mg Resmetirom in Subjects With Severe Renal Impairment and in Matched Healthy Control Subjects With Normal Renal Function | Phase 1 | Completed | Mar 6, 2024 | Sep 16, 2024 (actual) |
| NCT04643795 | Phase 1 Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Multiple Oral Doses of MGL-3196 in Subjects With Varying Degrees of Hepatic Impairment and Healthy Matched Control Subjects | 1 | Completed | Oct 25, 2018 | Aug 4, 2021 (actual) |
| NCT04197479 | A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Non Alcoholic Fatty Liver Disease Patients | 3 | Completed | Dec 16, 2019 | Jan 6, 2023 (actual) |
| NCT01367873 | Ascending Single-Dose Study to Evaluate VIA-3196 in Healthy Subjects | Phase 1 | Completed | 2011-06 | 2011-10 (actual) |
| NCT02542969 | Drug Interaction Study of MGL-3196 With Rosuvastatin and Simvastatin | Phase 1 | Completed | 2015-09 | 2015-10 (actual) |
| NCT04671069 | Drug Interaction Study of MGL-3196 With Clopidogrel | Phase 1 | Completed | Jul 26, 2019 | Aug 30, 2019 (actual) |
| NCT04671056 | Drug Interaction Study of MGL-3196 With Pioglitazone | Phase 1 | Completed | Nov 9, 2018 | Dec 11, 2018 (actual) |
| NCT03413124 | Bioavailability Study of MGL-3196 Tablets Compared to Capsules | Phase 1 | Completed | Feb 5, 2018 | Feb 17, 2018 (actual) |
| NCT03220165 | Radiolabeled Study to Determine the Mass Balance of [14C] MGL-3196 | Phase 1 | Completed | Aug 6, 2017 | Sep 3, 2017 (actual) |
| NCT02749578 | Drug Interaction Study of MGL-3196 With Atorvastatin | Phase 1 | Completed | 2016-04 | 2016-05 (actual) |
| NCT01519531 | Ascending Multiple-Dose Study to Evaluate VIA-3196 in Healthy Subjects | Phase 1 | Completed | 2012-01 | 2012-11 (actual) |
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