COMPANY
Merck & Co., Inc.
FDA-approved therapeutic company FDA-cleared device company Clinical Phase 3
No verified company description yet.
Hiring
| Title | Location (from posting) | Employer posted | First seen |
|---|---|---|---|
| Sr. Specialist, AI Engineering | Hyderabad, India | Oct 23, 2026 | Oct 8, 2026 |
| Senior Specialist, Business Insights & Analytics | Mumbai, India | Oct 23, 2026 | Oct 8, 2026 |
| Coordinateur Administration de Projets (H/F/D) - CDD 6 mois | Paris, France | Oct 23, 2026 | Oct 7, 2026 |
| Senior Specialist , Technology Partnership | Mumbai, India | Oct 23, 2026 | Oct 7, 2026 |
| R&D Oncology Japan Clinical Director (Non-MD) | JPN - Tokyo - Chiyoda | Oct 23, 2026 | Oct 7, 2026 |
Trial and FDA signals
- New trial + clinical hiring Started a Phase 3 trial (NCT07743164, actual start Oct 7, 2026) (+13 other new trials); 93 clinical-operations roles open. ClinicalTrials.gov NCT07743164 (Oct 7, 2026)
Evidence (14 events)
- Oct 7, 2026 · ClinicalTrials.gov NCT07743164
leadSponsor.name='Merck Sharp & Dohme LLC'; phases=['PHASE3']; overallStatus=RECRUITING; startDateStruct={date:2026-10-07,type:ACTUAL}; studyFirstPostDate=2026-08-03; briefTitle='A Clinical Trial of Raludotatug Deruxtecan (R-DXd) With or Without Bevacizumab in Participants With Ovarian Cancer Who Have Progressed Durin' - Sep 25, 2026 · ClinicalTrials.gov NCT07705607
leadSponsor.name='Merck Sharp & Dohme LLC'; phases=['PHASE3']; overallStatus=RECRUITING; startDateStruct={date:2026-09-25,type:ACTUAL}; studyFirstPostDate=2026-07-15; briefTitle='A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-005)' - Sep 18, 2026 · ClinicalTrials.gov NCT07776691
leadSponsor.name='Merck Sharp & Dohme LLC'; phases=['PHASE3']; overallStatus=RECRUITING; startDateStruct={date:2026-09-18,type:ACTUAL}; studyFirstPostDate=2026-08-20; briefTitle='A Study of Raludotatug Deruxtecan With or Without Bevacizumab as First-Line Maintenance Treatment in Non-HRD-Positive Advanced Ovarian Cance' - Aug 27, 2026 · ClinicalTrials.gov NCT07705555
leadSponsor.name='Merck Sharp & Dohme LLC'; phases=['PHASE3']; overallStatus=RECRUITING; startDateStruct={date:2026-08-27,type:ACTUAL}; studyFirstPostDate=2026-07-15; briefTitle='A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-004)' - Oct 7, 2026 · ClinicalTrials.gov NCT07785609
leadSponsor.name='Merck Sharp & Dohme LLC'; phases=['PHASE2']; overallStatus=RECRUITING; startDateStruct={date:2026-10-07,type:ACTUAL}; studyFirstPostDate=2026-08-25; briefTitle='A Clinical Trial of MK-2010 With Sacituzumab Tirumotecan (Sac-TMT) in Participants With Solid Tumors (MK-2010)' - Sep 17, 2026 · ClinicalTrials.gov NCT07646860
leadSponsor.name='Merck Sharp & Dohme LLC'; phases=['PHASE2']; overallStatus=RECRUITING; startDateStruct={date:2026-09-17,type:ACTUAL}; studyFirstPostDate=2026-06-15; briefTitle='A Study of Sotatercept (MK-7962) in Japanese Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-032)' - Sep 10, 2026 · ClinicalTrials.gov NCT07743151
leadSponsor.name='Merck Sharp & Dohme LLC'; phases=['PHASE1']; overallStatus=RECRUITING; startDateStruct={date:2026-09-10,type:ACTUAL}; studyFirstPostDate=2026-08-03; briefTitle='A Clinical Trial of MK-1406 in Healthy Participants (MK-1406-008)' - Sep 8, 2026 · ClinicalTrials.gov NCT07734610
leadSponsor.name='Merck Sharp & Dohme LLC'; phases=['PHASE1']; overallStatus=RECRUITING; startDateStruct={date:2026-09-08,type:ACTUAL}; studyFirstPostDate=2026-07-29; briefTitle='A Clinical Trial of Nemtabrutinib in Participants With Severe Kidney Disease (MK-1026-027)' - Aug 31, 2026 · ClinicalTrials.gov NCT07776665
leadSponsor.name='Merck Sharp & Dohme LLC'; phases=['PHASE1']; overallStatus=ACTIVE_NOT_RECRUITING; startDateStruct={date:2026-08-31,type:ACTUAL}; studyFirstPostDate=2026-08-20; briefTitle='A Clinical Trial of Enlicitide (MK-0616) Formulations in Healthy Participants (MK-0616-044)' - Aug 25, 2026 · ClinicalTrials.gov NCT07748351
leadSponsor.name='Merck Sharp & Dohme LLC'; phases=['PHASE1']; overallStatus=ACTIVE_NOT_RECRUITING; startDateStruct={date:2026-08-25,type:ACTUAL}; studyFirstPostDate=2026-08-05; briefTitle='A Clinical Trial of Multiple Formulations of MK-4082 in Healthy Overweight and Obese Participants (MK-4082-007)' - Aug 17, 2026 · ClinicalTrials.gov NCT07595263
leadSponsor.name='Merck Sharp & Dohme LLC'; phases=['PHASE1']; overallStatus=RECRUITING; startDateStruct={date:2026-08-17,type:ACTUAL}; studyFirstPostDate=2026-05-19; briefTitle='A Study of Ulonivirine (MK-8507) and Methadone in Healthy Volunteers (MK-8507-019)' - Aug 14, 2026 · ClinicalTrials.gov NCT07677163
leadSponsor.name='Merck Sharp & Dohme LLC'; phases=['PHASE1']; overallStatus=COMPLETED; startDateStruct={date:2026-08-14,type:ACTUAL}; studyFirstPostDate=2026-06-30; briefTitle='A Clinical Trial of MK-1403 in Healthy Participants (MK-1403-007)' - Aug 12, 2026 · ClinicalTrials.gov NCT07712575
leadSponsor.name='Merck Sharp & Dohme LLC'; phases=['PHASE1']; overallStatus=RECRUITING; startDateStruct={date:2026-08-12,type:ACTUAL}; studyFirstPostDate=2026-07-17; briefTitle='A Study of V132 in Healthy Older Participants (V132-001)' - Jul 20, 2026 · ClinicalTrials.gov NCT07697625
leadSponsor.name='Merck Sharp & Dohme LLC'; phases=['PHASE1']; overallStatus=RECRUITING; startDateStruct={date:2026-07-20,type:ACTUAL}; studyFirstPostDate=2026-07-13; briefTitle='A Clinical Trial of MK-4082 in Healthy Participants (MK-4082-005)'
- Oct 7, 2026 · ClinicalTrials.gov NCT07743164
- Drug approval + hiring FDA novel approval for LIPFENDRA (NDA 220848, Jul 15, 2026; +1 other approval); 463 manufacturing/quality or commercial roles open. FDA NDA 220848 (Jul 15, 2026)
Evidence (2 events)
- Jul 15, 2026 · FDA NDA 220848
openFDA drugsfda: application_number=NDA220848; sponsor_name='MSD'; submission_type=ORIG; submission_number=1; submission_status=AP; submission_status_date=20260715; submission_class_code=TYPE 1; brand_name=['LIPFENDRA'] - Apr 20, 2026 · FDA NDA 216964
openFDA drugsfda: application_number=NDA216964; sponsor_name='MSD'; submission_type=ORIG; submission_number=1; submission_status=AP; submission_status_date=20260420; submission_class_code=TYPE 1/4; brand_name=['IDVYNSO']
- Jul 15, 2026 · FDA NDA 220848
Timeline
- Trial start Phase 2: DOR/ISL in Pediatric Participants With HIV-1, <18 Years of Age and ≥ 35 kg source ↗
- Trial start Phase 1: A Clinical Trial of MK-6916 With Midazolam and Rosuvastatin in Healthy Participants (MK-6916-012) source ↗
- Trial start Phase 2: A Clinical Trial of MK-6916 in Participants With Pain After Bunion Removal Surgery (MK-6916-007) source ↗
- Trial start Phase 2: A Clinical Trial of Tulisokibart (MK-7240) in Participants With Pulmonary Sarcoidosis (MK-7240-016) source ↗
- Trial start Phase 2: A Clinical Trial of MK-2010 Alone and With Other Treatments in Participants With Advanced Solid Tumors (MK-2010-002) source ↗
- Trial start Phase 2: A Clinical Trial of MK-2010 With Sacituzumab Tirumotecan (Sac-TMT) in Participants With Solid Tumors (MK-2010) source ↗
- Trial start Phase 2: A Clinical Trial of MK-1045 in People With B-cell Cancer (MK-1045-006) source ↗
- Board tracked Radar started tracking this company’s job board (1,137 open jobs at last check). source ↗
- Trial start Phase 3: A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-005) source ↗
- Trial start Phase 3: A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-004) source ↗
- Trial start Phase 1: A Clinical Trial of MK-1403 in Healthy Participants (MK-1403-007) source ↗
- Trial start Phase 2/Phase 3: A Clinical Trial of MK-1045 and Rituximab in People With Follicular Lymphoma (MK-1045-007) source ↗
- Trial start Phase 3: A Clinical Trial of Calderasib (MK-1084) and Durvalumab in People With Non-Small Cell Lung Cancer (MK-1084-015/KANDLELIT-015) source ↗
- Trial start Phase 1: Clinical Study of MK-4884 in Participants With Advanced or Metastatic Solid Tumors (MK-4884-001) source ↗
- Trial start Phase 2/Phase 3: A Clinical Trial of MK-1045 in People With B-cell Acute Lymphoblastic Leukemia (MK-1045-005) source ↗
- Trial start Phase 3: A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014) source ↗
- Trial start Phase 1/Phase 2: A Clinical Study of MK-1045 in People With Non-Hodgkin Lymphoma (MK-1045-008) source ↗
- Trial start Phase 3: A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031) source ↗
- Trial start Phase 3: MK-3475A±Calderasib (MK-1084) in Completely Resected Stage IIA-IIIB (N2) KRAS G12Cm NSCLC (MK-1084-013) source ↗
- Trial start Phase 1/Phase 2: A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003) source ↗
- Trial start Phase 2: A Clinical Study of Calderasib (MK-1084) in People With Advanced Solid Tumors (MK-1084-014) source ↗
- Trial start Phase 3: A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007) source ↗
- Trial start Phase 2/Phase 3: A Study of Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029) source ↗
- Trial start Phase 2: A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015) source ↗
- Trial start Phase 3: A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016) source ↗
Upcoming milestones
- Feb 9, 2027 (ESTIMATED) · Phase 1 · A Clinical Trial of MK-6916 With Midazolam and Rosuvastatin in Healthy Participants (MK-6916-012) · NCT07862621
- Jun 10, 2027 (ESTIMATED) · Phase 2 · A Clinical Trial of MK-6916 in Participants With Pain After Bunion Removal Surgery (MK-6916-007) · NCT07862595
- Jun 11, 2027 (ESTIMATED) · Phase 1/Phase 2 · A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Program · NCT05319730
- Sep 24, 2027 (ESTIMATED) · Phase 2/Phase 3 · A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003) · NCT05139017
- Nov 4, 2027 (ESTIMATED) · Phase 2 · A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015) · NCT06979596
- Dec 13, 2027 (ESTIMATED) · Phase 2 · A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell L · NCT06890884
- Jan 24, 2028 (ESTIMATED) · Phase 3 · A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score · NCT06345729
- May 10, 2028 (ESTIMATED) · Phase 3 · A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004) · NCT06136650
Open jobs 1,137
| Title | Location (from posting, not HQ) | Employer posted | First seen | Level |
|---|---|---|---|---|
| Sr. Specialist, AI Engineering | Hyderabad, India | Oct 23, 2026 | Oct 8, 2026 | Not stated |
| Senior Specialist, Business Insights & Analytics | Mumbai, India | Oct 23, 2026 | Oct 8, 2026 | Senior |
| Coordinateur Administration de Projets (H/F/D) - CDD 6 mois | Paris, France | Oct 23, 2026 | Oct 7, 2026 | Mid |
| Senior Specialist , Technology Partnership | Mumbai, India | Oct 23, 2026 | Oct 7, 2026 | Not stated |
| R&D Oncology Japan Clinical Director (Non-MD) | JPN - Tokyo - Chiyoda | Oct 23, 2026 | Oct 7, 2026 | Senior |
| Director Strategic Planning | 2 locations, including Rahway, New Jersey, USA | Oct 23, 2026 | Oct 17, 2026 | Not stated |
| Specialist, SAP Data Analytics | Hyderabad, India | Oct 23, 2026 | Oct 17, 2026 | Not stated |
| Sr. Key Account Manager, Retail | Chengdu, China | Oct 23, 2026 | Oct 20, 2026 | Not stated |
| Pharm Technician (WDA) | Singapore | Oct 23, 2026 | Oct 20, 2026 | Not stated |
| Assoc. Spclst, Engineering (WDA) | Singapore | Oct 23, 2026 | Oct 23, 2026 | Not stated |
| AtR General Ledger Specialist (Fixed Term) | Prague, Czechia | Oct 23, 2026 | Oct 23, 2026 | Not stated |
| Senior Manager, ServiceNow Senior Developer - Operational Technology | Hyderabad, India | Oct 23, 2026 | Oct 23, 2026 | Not stated |
| Sr. Spclst, Quality Assurance (Upstream) | IRL - Meath - Dunboyne | Oct 23, 2026 | Oct 23, 2026 | Not stated |
| Vaccine Customer Specialist (Multiple Locations) | Warsaw, Poland | Oct 23, 2026 | Oct 23, 2026 | Not stated |
| Intern – HBO/WO Business administration or Data Analytics – Intellectual Property | NLD - North Brabant - Boxmeer | Oct 23, 2026 | Oct 23, 2026 | Not stated |
| Sales Team Leader (North Central Poland) | POL - Poland - Poland | Oct 23, 2026 | Oct 23, 2026 | Not stated |
| Specialist, AI Engineering | Hyderabad, India | Oct 23, 2026 | Oct 23, 2026 | Not stated |
| Associate Director, FPP Engagement & Enablement Lead, AP | 12 locations, including Singapore Boulevard Towers, Singapore, SGP | Oct 23, 2026 | Oct 23, 2026 | Not stated |
| Pharmaceutical Information Specialist | CHN - Guangzhou - Tianhe | Oct 23, 2026 | Oct 23, 2026 | Not stated |
| Senior Professional Sales Specialist | TWN - Taipei - Taipei City | Oct 23, 2026 | Oct 23, 2026 | Not stated |
| Associate Director, Drug Product, Quality Assurance | Wilmington, DE | Oct 22, 2026 | Oct 8, 2026 | Senior |
| Senior Specialist Engineering (Onsite) | USA - New Jersey - Rahway | Oct 22, 2026 | Oct 8, 2026 | Senior |
| Associate Director Regional Market Access | 2 locations, including North Wales Upper Gwynedd, Pennsylvania, USA | Oct 22, 2026 | Oct 7, 2026 | Senior |
| Spclst, Scitara Technical Analyst | Hyderabad, India | Oct 22, 2026 | Oct 7, 2026 | Mid |
| Associate Director, Quality Control | IRL - Carlow - Carlow | Oct 22, 2026 | Oct 7, 2026 | Senior |
| Bioprocess Technician | NLD - Utrecht - De Bilt | Oct 22, 2026 | Oct 7, 2026 | Entry |
| Post Doc Fellow-Immunogenicity Prediction | USA - Pennsylvania - West Point | Oct 22, 2026 | Oct 7, 2026 | Not stated |
| Sr. Spclst, Marketing | North Wales, PA | Oct 22, 2026 | Oct 7, 2026 | Not stated |
| Rare Disease Account Specialist, PAH - Colorado | 2 locations, including Denver, Colorado, USA | Oct 22, 2026 | Oct 7, 2026 | Not stated |
| 2027 Future Talent Program - Global Supplier Management Group Supplier Development & Performance Management - Intern | 2 locations, including West Point, Pennsylvania, USA | Oct 22, 2026 | Oct 7, 2026 | Not stated |
| Senior Operator Visuele Inspectie | NLD - North Brabant - Boxmeer | Oct 22, 2026 | Oct 7, 2026 | Senior |
| Operational Coach (Start-up Phase) | NLD - North Brabant - Boxmeer | Oct 22, 2026 | Oct 7, 2026 | Mid |
| Senior Validatie/Kwalificatie Engineer | NLD - North Brabant - Boxmeer | Oct 22, 2026 | Oct 7, 2026 | Senior |
| Operator (Dagdienst) | NLD - North Brabant - Boxmeer | Oct 22, 2026 | Oct 7, 2026 | Entry |
| Director, Global Oncology Marketing - Prostate Cancer | 2 locations, including Rahway, New Jersey, USA | Oct 22, 2026 | Oct 9, 2026 | Senior |
| Clinical Programmer | San Jose, Costa Rica | Oct 22, 2026 | Oct 14, 2026 | Not stated |
| Associate Director, U.S. Account Management Strategy | North Wales, PA | Oct 22, 2026 | Oct 17, 2026 | Not stated |
| Senior Director, Clinical Science, Infectious Disease, Hybrid | 4 locations, including Rahway, New Jersey, USA | Oct 22, 2026 | Oct 17, 2026 | Not stated |
| HIV Customer Representative - New Orleans Territory Mirror | 2 locations, including North Wales Upper Gwynedd, Pennsylvania, USA | Oct 22, 2026 | Oct 17, 2026 | Not stated |
| Senior. Specialist, Software Engineering (CIAM) | 2 locations, including Hyderabad Hitec City Raidurg, Telangana, IND | Oct 22, 2026 | Oct 17, 2026 | Not stated |
| Senior Specialist, Platform Architect (CIAM) | 2 locations, including Hyderabad Hitec City Raidurg, Telangana, IND | Oct 22, 2026 | Oct 17, 2026 | Not stated |
| Senior Specialist, Technical Product Management | Hyderabad, India | Oct 22, 2026 | Oct 17, 2026 | Not stated |
| Associate Director, Clinical Research Associate Manager | Mumbai, India | Oct 22, 2026 | Oct 17, 2026 | Not stated |
| Functional Area Geography Associate Director, GDMS Clinical Data Management | Warsaw, Poland | Oct 22, 2026 | Oct 17, 2026 | Not stated |
| Associate Specialist, Clinical Data Management | 2 locations, including West Point, Pennsylvania, USA | Oct 22, 2026 | Oct 23, 2026 | Not stated |
| Senior Technician, Operations | Millsboro, DE | Oct 22, 2026 | Oct 23, 2026 | Not stated |
| Associate Technician, Operations | USA - Texas - Irving | Oct 22, 2026 | Oct 23, 2026 | Not stated |
| Technician, Operations | Millsboro, DE | Oct 22, 2026 | Oct 23, 2026 | Not stated |
| Senior Medical Writer, Safety Support Services | 3 locations, including Bogot Colpatria, Cundinamarca, COL | Oct 22, 2026 | Oct 23, 2026 | Not stated |
| Senior Technician (Process), Operations | USA - North Carolina - Wilson | Oct 22, 2026 | Oct 23, 2026 | Not stated |
Clinical trials (lead sponsor) Showing 50 of 1,369
| Record | Title | Phase | Status | Start | Primary completion |
|---|---|---|---|---|---|
| NCT07705555 | A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-004) | Phase 3 | Recruiting | Aug 27, 2026 | Oct 31, 2028 (estimated) |
| NCT07785609 | A Clinical Trial of MK-2010 With Sacituzumab Tirumotecan (Sac-TMT) in Participants With Solid Tumors (MK-2010) | Phase 2 | Recruiting | Oct 9, 2026 | Sep 30, 2031 (estimated) |
| NCT07227597 | A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003) | Phase 1/Phase 2 | Recruiting | Jan 29, 2026 | Nov 29, 2030 (estimated) |
| NCT07513376 | A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014) | Phase 3 | Recruiting | May 4, 2026 | Aug 22, 2034 (estimated) |
| NCT07705607 | A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-005) | Phase 3 | Recruiting | Sep 25, 2026 | Nov 30, 2028 (estimated) |
| NCT07554339 | A Clinical Trial of Calderasib (MK-1084) and Durvalumab in People With Non-Small Cell Lung Cancer (MK-1084-015/KANDLELIT-015) | Phase 3 | Recruiting | Jun 18, 2026 | Dec 15, 2032 (estimated) |
| NCT07867938 | A Clinical Trial of Tulisokibart (MK-7240) in Participants With Pulmonary Sarcoidosis (MK-7240-016) | Phase 2 | Not yet recruiting | Nov 6, 2026 | Oct 5, 2029 (estimated) |
| NCT07677163 | A Clinical Trial of MK-1403 in Healthy Participants (MK-1403-007) | Phase 1 | Completed | Aug 14, 2026 | Oct 5, 2026 (actual) |
| NCT06863272 | A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02) | Phase 1/Phase 2 | Recruiting | Jul 3, 2025 | Oct 1, 2031 (estimated) |
| NCT06890884 | A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011) | Phase 2 | Recruiting | Apr 11, 2025 | Dec 13, 2027 (estimated) |
| NCT06623409 | Safety and Immunogenicity of V540B in Healthy Adults (V540B-002). | Phase 1 | Recruiting | Nov 12, 2024 | May 31, 2028 (estimated) |
| NCT06925737 | A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001) | Phase 3 | Recruiting | May 13, 2025 | Jun 26, 2028 (estimated) |
| NCT07060807 | A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016) | Phase 3 | Recruiting | Jul 21, 2025 | Jul 14, 2033 (estimated) |
| NCT07519772 | A Clinical Study of MK-1045 in People With Non-Hodgkin Lymphoma (MK-1045-008) | Phase 1/Phase 2 | Recruiting | May 3, 2026 | Jul 1, 2030 (estimated) |
| NCT07033494 | A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004) | Phase 2 | Recruiting | Jul 16, 2025 | Apr 30, 2029 (estimated) |
| NCT07793942 | A Clinical Trial of MK-2010 Alone and With Other Treatments in Participants With Advanced Solid Tumors (MK-2010-002) | Phase 2 | Not yet recruiting | Oct 27, 2026 | Sep 26, 2028 (estimated) |
| NCT05139017 | A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003) | Phase 2/Phase 3 | Recruiting | Jan 14, 2022 | Sep 24, 2027 (estimated) |
| NCT03924856 | Perioperative Pembrolizumab (MK-3475) Plus Neoadjuvant Chemotherapy Versus Perioperative Placebo Plus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle-invasive Bladder Cancer (MIBC) (MK-3475-866/KEYNOTE-866) | Phase 3 | Completed | Jun 13, 2019 | Jan 26, 2026 (actual) |
| NCT07218029 | A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038) | Phase 3 | Active, not recruiting | May 12, 2021 | Dec 7, 2028 (estimated) |
| NCT07709000 | A Clinical Trial of MK-1045 in People With B-cell Cancer (MK-1045-006) | Phase 2 | Not yet recruiting | Oct 9, 2026 | Nov 16, 2033 (estimated) |
| NCT07570173 | A Clinical Trial of MK-1045 in People With B-cell Acute Lymphoblastic Leukemia (MK-1045-005) | Phase 2/Phase 3 | Recruiting | May 18, 2026 | Oct 18, 2033 (estimated) |
| NCT07634471 | A Clinical Trial of MK-1045 and Rituximab in People With Follicular Lymphoma (MK-1045-007) | Phase 2/Phase 3 | Recruiting | Jun 22, 2026 | Jul 23, 2032 (estimated) |
| NCT05067283 | A Study of Calderasib (MK-1084) in KRAS Mutant Advanced Solid Tumors (MK-1084-001) | Phase 1 | Recruiting | Dec 17, 2021 | Feb 25, 2030 (estimated) |
| NCT05319730 | A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B) | Phase 1/Phase 2 | Recruiting | May 16, 2023 | Jun 11, 2027 (estimated) |
| NCT07190248 | A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007) | Phase 3 | Recruiting | Oct 8, 2025 | Dec 7, 2029 (estimated) |
| NCT06469944 | Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06) | Phase 1/Phase 2 | Recruiting | Sep 20, 2024 | Sep 12, 2029 (estimated) |
| NCT07209111 | A Clinical Study of Calderasib (MK-1084) in People With Advanced Solid Tumors (MK-1084-014) | Phase 2 | Recruiting | Dec 4, 2025 | Apr 9, 2032 (estimated) |
| NCT07058077 | A Study of Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029) | Phase 2/Phase 3 | Recruiting | Aug 21, 2025 | Dec 4, 2033 (estimated) |
| NCT07431827 | MK-3475A±Calderasib (MK-1084) in Completely Resected Stage IIA-IIIB (N2) KRAS G12Cm NSCLC (MK-1084-013) | Phase 3 | Recruiting | Mar 18, 2026 | Oct 26, 2039 (estimated) |
| NCT06731907 | A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01) | Phase 2 | Recruiting | Mar 30, 2025 | Mar 12, 2032 (estimated) |
| NCT03486873 | Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587) | Phase 3 | Recruiting | Aug 21, 2018 | Aug 4, 2043 (estimated) |
| NCT06997497 | A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012) | Phase 3 | Recruiting | Jul 16, 2025 | Mar 28, 2029 (estimated) |
| NCT06345729 | A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004) | Phase 3 | Recruiting | May 24, 2024 | Jan 24, 2028 (estimated) |
| NCT06780098 | Substudy 01I: A Study of Investigational Agents in Participants With Previously Treated Stage IV Squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01I/KEYMAKER-U01I) | Phase 2 | Recruiting | May 28, 2025 | Mar 2, 2032 (estimated) |
| NCT07862621 | A Clinical Trial of MK-6916 With Midazolam and Rosuvastatin in Healthy Participants (MK-6916-012) | Phase 1 | Not yet recruiting | Nov 30, 2026 | Feb 9, 2027 (estimated) |
| NCT07862569 | DOR/ISL in Pediatric Participants With HIV-1, <18 Years of Age and ≥ 35 kg | Phase 2 | Not yet recruiting | Dec 23, 2026 | Sep 24, 2029 (estimated) |
| NCT04956692 | Study of Pembrolizumab (MK-3475) Subcutaneous (SC) Versus Pembrolizumab Intravenous (IV) Administered With Platinum Doublet Chemotherapy in Participants With Metastatic Squamous or Nonsquamous Non-Small Cell Lung Cancer (NSCLC) (MK-3475-A86) | Phase 3 | Completed | Aug 5, 2021 | Apr 4, 2023 (actual) |
| NCT07862595 | A Clinical Trial of MK-6916 in Participants With Pain After Bunion Removal Surgery (MK-6916-007) | Phase 2 | Not yet recruiting | Nov 23, 2026 | Jun 10, 2027 (estimated) |
| NCT04924075 | Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015) | Phase 2 | Recruiting | Aug 12, 2021 | Nov 18, 2032 (estimated) |
| NCT06843447 | A Clinical Study of Raludotatug Deruxtecan in People With Ovarian Cancer (MK-5909-003) | Phase 1/Phase 2 | Recruiting | Apr 15, 2025 | Mar 27, 2029 (estimated) |
| NCT06395103 | Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01) | Phase 1/Phase 2 | Recruiting | Aug 16, 2024 | Mar 31, 2029 (estimated) |
| NCT06841354 | A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011) | Phase 3 | Recruiting | Mar 16, 2025 | May 18, 2030 (estimated) |
| NCT06941272 | A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01) | Phase 1/Phase 2 | Recruiting | May 26, 2025 | Dec 30, 2030 (estimated) |
| NCT07419295 | A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031) | Phase 3 | Recruiting | Apr 23, 2026 | Jul 27, 2029 (estimated) |
| NCT06136650 | A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004) | Phase 3 | Recruiting | Dec 18, 2023 | May 10, 2028 (estimated) |
| NCT06353386 | Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A) | Phase 1/Phase 2 | Recruiting | May 20, 2024 | Jan 15, 2029 (estimated) |
| NCT06979596 | A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015) | Phase 2 | Recruiting | Aug 11, 2025 | Nov 4, 2027 (estimated) |
| NCT06818643 | A Study to Evaluate the Safety and Efficacy of MK-3120 in Participants With Advanced Solid Tumors (MK-3120-002) | Phase 1/Phase 2 | Recruiting | Mar 25, 2025 | Mar 7, 2031 (estimated) |
| NCT07600749 | Clinical Study of MK-4884 in Participants With Advanced or Metastatic Solid Tumors (MK-4884-001) | Phase 1 | Recruiting | Jun 18, 2026 | Oct 4, 2029 (estimated) |
| NCT06428409 | A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A) | Phase 1/Phase 2 | Recruiting | Jun 20, 2024 | Oct 16, 2029 (estimated) |
NIH awards 4
- NIH award 5R33MH066623-05 FY2008: $320,631 awarded for that fiscal year; activity R33 (OTHER_NIH); PI MOZLEY, P. DAVID DAVID; recipient as written: MERCK AND COMPANY, RAHWAY, NJ. Development of Group II mGluR Radiotr source ↗
- NIH award 4R33MH066623-04 FY2007: $361,733 awarded for that fiscal year; activity R33 (OTHER_NIH); PI WATERHOUSE, RIKKI NOEL; recipient as written: MERCK AND COMPANY, RAHWAY, NJ. Development of Group II mGluR Radiotr source ↗
- NIH award 5R01MH062344-04 FY2003: $1,313,073 awarded for that fiscal year; activity R01 (OTHER_NIH); PI BARLOW, CARROLEE; recipient as written: MERCK AND COMPANY, RAHWAY, NJ. Molecular Genetic Mapping of the Mouse Br source ↗
- NIH award 7R01MH062344-03 FY2002: $1,100,698 awarded for that fiscal year; activity R01 (OTHER_NIH); PI BARLOW, CARROLEE; recipient as written: MERCK AND COMPANY, RAHWAY, NJ. Molecular Genetic Mapping of the Mouse Br source ↗
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