Biotech RadarJobs updated

COMPANY

Astellas

astellas.com ↗

Clinical Phase 3

Profile checked Oct 10, 2026

Keywords: Type 2 Diabetes Mellitus Hot Flashes Non-Small-Cell Lung Cancer Rheumatoid Arthritis Aspergillosis Invasive Fungal Infections Prostate Cancer Castration-Resistant Prostate Cancer Coronary Artery Disease Geographic Atrophy Age-Related Macular Degeneration AML With FLT3 Mutation Chronic Ischemic Stroke Metastatic Castration Resistant Prostate Cancer Pancreatic Ductal Adenocarcinoma Colorectal Cancer NSCLC Kidney Transplantation Progressive Metastatic Prostate Cancer Acute Myeloid Leukemia FLT3-mutated Acute Myeloid Leukemia Renal Anemia Primary Mitochondrial Myopathy Restless Legs Syndrome Invasive Candidiasis Candidemia Mycoses Prostatic Neoplasms Acute Kidney Injury Detrusor Overactivity Overactive Bladder Gastric Cancer Gastro-esophageal Junction (GEJ) Cancer Rhinitis, Allergic, Seasonal Urinary Incontinence Overactive Urinary Bladder Prostate Neoplasms

525Trials (company is sponsor)

Timeline

  1. Trial start Phase 3: A Study to Confirm if Fezolinetant Helps to Reduce Hot Flashes in Indian Women Going Through Menopause source ↗
  2. Trial start Phase 1/Phase 2: A Study of ASP2246 for People Who Have Movement Problems Caused by Brain Injury After a Stroke source ↗
  3. Trial start Phase 1: A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors source ↗
  4. Trial start Phase 4: A Study About the Safety of ASP3021 Eye Injections and if They Help People in Japan With Vision Loss From Age-related Macular Degeneration source ↗
  5. Trial start Phase 1: A Study to Find a Suitable Dose of ASP4396 in Adults With Solid Tumors source ↗
  6. Trial start Phase 3: A Study to Assess Long-term Safety of Fezolinetant Given to Japanese Women Going Through Menopause source ↗
  7. Trial start —: A Study to Compare the Use of Diabetes Treatment Support System (BAP0527 and Blood Glucose Meter) in Addition to Daily Practice and Treatment With Daily Practice and Treatment Alone in Patients Wit source ↗
  8. Trial start Phase 3: A Study to Confirm if Fezolinetant Helps Reduce Hot Flashes in Japanese Women Going Through Menopause source ↗
  9. Trial start Phase 1: A Study of ASP3082 in Adults With Advanced Solid Tumors source ↗
  10. Trial start Phase 2: A Study to Evaluate ASP0367 in Participants With Primary Mitochondrial Myopathy source ↗
  11. Trial start —: Post-marketing Surveillance of EVRENZO® Tablets (Roxadustat) in Patients With Renal Anemia source ↗
  12. Trial start Phase 2: Study to Evaluate the Efficacy of ASP1128 (MA-0217) in Subjects at Risk for Acute Kidney Injury (AKI) Following Coronary Artery Bypass Graft (CABG) and/or Valve Surgery source ↗
  13. Trial start —: Japan Post-Marketing Surveillance for Peficitinib to Assess Safety and Effectiveness in the Patients With Rheumatoid Arthritis source ↗
  14. Trial start Phase 4: A Safety and Efficacy Study of Enzalutamide in Indian Patients With Progressive Metastatic Castration-Resistant Prostate Cancer (mCRPC) Previously Treated With Docetaxel-Based Chemotherapy source ↗
  15. Trial start Not phased (device or behavioral study): A Study of IMAB362 in Japanese Subjects With Locally Advanced or Metastatic Gastric or Gastro-esophageal Junction (GEJ) Adenocarcinoma source ↗
  16. Trial start Phase 3: A Study of ASP2215 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase 3 (FLT3) Mutation source ↗
  17. Trial start Phase 2: A Dose-finding Study of ASP4070 source ↗
  18. Trial start Phase 4: A Study of Oral Dosing of Gabapentin Enacarbil in Japanese Restless Legs Syndrome Patients source ↗
  19. Trial start Phase 4: Study on Enzalutamide and Flutamide in Patients With Castration Resistant Prostate Cancer source ↗
  20. Trial start Phase 1/Phase 2: A Study of ASP2215 in Combination With Induction and Consolidation Chemotherapy in Patients With Newly Diagnosed Acute Myeloid Leukemia. source ↗
  21. Trial start —: Long-Term Specified Drug Use-Results Survey for Xtandi Capsule source ↗
  22. Trial start Phase 3: An Asian Study to Evaluate Efficacy and Safety of Oral Enzalutamide in Progressive Metastatic Prostate Cancer Participants source ↗
  23. Trial start Phase 2: A Study to Evaluate the Safety and Efficacy of ASP015K in Moderate to Severe Rheumatoid Arthritis Subjects Who Have Had an Inadequate Response to Methotrexate source ↗
  24. Trial start Phase 2: A Study to Assess the Safety of Continued Administration of MDV3100 in Subjects With Prostate Cancer Who Showed Benefit From Prior Exposure to MDV3100 source ↗
  25. Trial start Phase 3: Efficacy Confirmation Study of CDP870 in Early Rheumatoid Arthritis source ↗

Showing 25 of 50 dated events.

Upcoming milestones

Estimated primary completion per ClinicalTrials.gov. Dates move.

Clinical trials (lead sponsor) Showing 50 of 525

RecordTitlePhaseStatusStartPrimary completion
NCT05382559A Study of ASP3082 in Adults With Advanced Solid TumorsPhase 1RecruitingJun 8, 2022Dec 31, 2028 (estimated)
NCT06970665A Study About the Safety of ASP3021 Eye Injections and if They Help People in Japan With Vision Loss From Age-related Macular DegenerationPhase 4Active, not recruitingJul 8, 2025Jun 30, 2027 (estimated)
NCT06156696A Study to Compare the Use of Diabetes Treatment Support System (BAP0527 and Blood Glucose Meter) in Addition to Daily Practice and Treatment With Daily Practice and Treatment Alone in Patients With Type 2 Diabetes MellitusNot listedCompletedFeb 16, 2024Jul 2, 2025 (actual)
NCT07829653A Study to Confirm if Fezolinetant Helps to Reduce Hot Flashes in Indian Women Going Through MenopausePhase 3Not yet recruitingOct 31, 2026Mar 31, 2028 (estimated)
NCT03182244A Study of ASP2215 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase 3 (FLT3) MutationPhase 3CompletedOct 25, 2017Dec 25, 2023 (actual)
NCT06364696A Study to Find a Suitable Dose of ASP4396 in Adults With Solid TumorsPhase 1TerminatedApr 16, 2024Jun 17, 2026 (actual)
NCT07318714A Study of ASP2246 for People Who Have Movement Problems Caused by Brain Injury After a StrokePhase 1/Phase 2RecruitingApr 3, 2026Feb 28, 2030 (estimated)
NCT03641560A Safety and Efficacy Study of Enzalutamide in Indian Patients With Progressive Metastatic Castration-Resistant Prostate Cancer (mCRPC) Previously Treated With Docetaxel-Based ChemotherapyPhase 4CompletedSep 19, 2018Feb 20, 2024 (actual)
NCT03971253Japan Post-Marketing Surveillance for Peficitinib to Assess Safety and Effectiveness in the Patients With Rheumatoid ArthritisNot listedCompletedSep 2, 2019May 29, 2026 (actual)
NCT07094204A Study to Find a Suitable Dose of ASP5834 in Adults With Solid TumorsPhase 1RecruitingJul 25, 2025Nov 30, 2028 (estimated)
NCT06206421A Study to Assess Long-term Safety of Fezolinetant Given to Japanese Women Going Through MenopausePhase 3CompletedFeb 22, 2024Mar 19, 2026 (actual)
NCT06206408A Study to Confirm if Fezolinetant Helps Reduce Hot Flashes in Japanese Women Going Through MenopausePhase 3CompletedFeb 16, 2024Oct 22, 2025 (actual)
NCT01186861Phase 2 Study of Maintenance OSI-906 Plus Erlotinib (Tarceva®), or Placebo Plus Erlotinib in Patients With Nonprogression Following 4 Cycles of Platinum-based Chemotherapy2CompletedMar 4, 2011Jul 1, 2013 (actual)
NCT01221077Study of Erlotinib (Tarceva®) in Combination With OSI-906 in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) With Activating Mutations of the Epidermal Growth Factor Receptor (EGFR) GenePhase 2CompletedApr 8, 2011Mar 1, 2013 (actual)
NCT01279538A Study to Assess Pharmacokinetic, Pharmacodynamic, Safety and Tolerability of ASKP1240 in de Novo Kidney TransplantationPhase 1CompletedNov 17, 2010Jan 23, 2012 (actual)
NCT02294461An Asian Study to Evaluate Efficacy and Safety of Oral Enzalutamide in Progressive Metastatic Prostate Cancer ParticipantsPhase 3CompletedApr 23, 2014Sep 20, 2015 (actual)
NCT02310321A Study of ASP2215 in Combination With Induction and Consolidation Chemotherapy in Patients With Newly Diagnosed Acute Myeloid Leukemia.Phase 1/Phase 2CompletedFeb 26, 2015Aug 25, 2021 (actual)
NCT04408820Post-marketing Surveillance of EVRENZO® Tablets (Roxadustat) in Patients With Renal AnemiaNot listedCompletedJun 1, 2020Jun 23, 2025 (actual)
NCT04641962A Study to Evaluate ASP0367 in Participants With Primary Mitochondrial MyopathyPhase 2TerminatedMay 24, 2021May 8, 2024 (actual)
NCT01242202A Study to Assess the Safety and Efficacy of ASP1941 in Combination With α-glucosidase Inhibitor in Type 2 Diabetic PatientsPhase 3CompletedOct 21, 2010May 25, 2012 (actual)
NCT01054092A Study to Assess the Long-term Safety and Efficacy of ASP1941 in Japanese Diabetic PatientsPhase 3CompletedJan 14, 2010Jul 22, 2011 (actual)
NCT01242228A Study to Assess the Safety and Efficacy of ASP1941 in Combination With Dipeptidyl Peptidase-4 (DPP-4) Inhibitor in Type 2 Diabetic PatientsPhase 3CompletedOct 21, 2010Jun 6, 2012 (actual)
NCT01316107A Study to Assess Safety and Efficacy of ASP1941 in Combination With Nateglinide in Type 2 Diabetic PatientsPhase 3CompletedJan 15, 2011Oct 19, 2012 (actual)
NCT01057628A Study to Assess the Efficacy and Safety of ASP1941 in Japanese Type 2 Diabetes PatientsPhase 3CompletedJan 13, 2010Nov 6, 2010 (actual)
NCT01135433A Study to Assess the Efficacy and Safety of ASP1941 in Combination With Metformin in Type 2 Diabetic PatientsPhase 3CompletedMay 15, 2010Nov 28, 2011 (actual)
NCT01225081A Study to Assess the Efficacy and Safety of ASP1941 in Combination With Pioglitazone in Type 2 Diabetic PatientsPhase 3CompletedSep 15, 2010Apr 28, 2012 (actual)
NCT01242215A Study to Assess the Efficacy and Safety of ASP1941 in Combination With Sulfonylurea in Type 2 Diabetic PatientsPhase 3CompletedSep 17, 2010Apr 25, 2012 (actual)
NCT01554696A Study to Evaluate the Safety and Efficacy of ASP015K in Moderate to Severe Rheumatoid Arthritis Subjects Who Have Had an Inadequate Response to MethotrexatePhase 2CompletedJul 6, 2012Feb 11, 2014 (actual)
NCT01071850A Study to Evaluate the Effect of ASP1941 in Adult Patients With Type 2 Diabetes MellitusPhase 2CompletedMar 3, 2010Apr 11, 2011 (actual)
NCT01117584A Study to Evaluate the Effect of ASP1941 in Combination With Metformin in Adult Patients With Type 2 Diabetes MellitusPhase 2CompletedApr 6, 2010Apr 1, 2011 (actual)
NCT01316094A Study to Assess Efficacy and Safety of ASP1941 in Diabetic Patients With Renal ImpairmentPhase 3CompletedJan 18, 2011Nov 28, 2012 (actual)
NCT03053427A Study of Oral Dosing of Gabapentin Enacarbil in Japanese Restless Legs Syndrome PatientsPhase 4CompletedMar 30, 2017Jun 25, 2018 (actual)
NCT00634049Isavuconazole in the Treatment of Renally Impaired Aspergillosis and Rare FungiPhase 3CompletedApr 22, 2008Jan 3, 2014 (actual)
NCT00412893Isavuconazole (BAL8557) for Primary Treatment of Invasive AspergillosisPhase 3CompletedMar 7, 2007Mar 28, 2013 (actual)
NCT00413218Isavuconazole (BAL8557) in the Treatment of Candidemia and Other Invasive Candida InfectionsPhase 3CompletedMar 8, 2007Mar 3, 2015 (actual)
NCT02918968Study on Enzalutamide and Flutamide in Patients With Castration Resistant Prostate CancerPhase 4CompletedNov 2, 2016Mar 27, 2020 (actual)
NCT01451203Efficacy Confirmation Study of CDP870 in Early Rheumatoid ArthritisPhase 3CompletedOct 11, 2011Aug 28, 2013 (actual)
NCT01288911A Study of Enzalutamide Versus Bicalutamide in Castrate Men With Metastatic Prostate CancerPhase 2CompletedMar 22, 2011Oct 19, 2014 (actual)
NCT01534052A Study to Assess the Safety of Continued Administration of MDV3100 in Subjects With Prostate Cancer Who Showed Benefit From Prior Exposure to MDV3100Phase 2CompletedOct 21, 2011Apr 18, 2017 (actual)
NCT01334918A Study of Regadenoson in Subjects Undergoing Stress Myocardial Perfusion Imaging (MPI) Using Multidetector Computed Tomography (MDCT) Compared to Single Photon Emission Computed Tomography (SPECT)Phase 2CompletedApr 26, 2011Jul 2, 2012 (actual)
NCT03941483Study to Evaluate the Efficacy of ASP1128 (MA-0217) in Subjects at Risk for Acute Kidney Injury (AKI) Following Coronary Artery Bypass Graft (CABG) and/or Valve SurgeryPhase 2CompletedNov 1, 2019Jul 26, 2021 (actual)
NCT00826280Caffeine's Effect on Regadenoson Administration With Single Photon Emission Computed Tomography (SPECT) Myocardial Perfusion Imaging (MPI)Phase 3CompletedMar 24, 2009Jul 15, 2010 (actual)
NCT01093534Study of 2 Doses of Solifenacin Succinate in Female Subjects With Overactive Bladder.Phase 4CompletedJan 19, 2010Jun 23, 2011 (actual)
NCT03528629A Study of IMAB362 in Japanese Subjects With Locally Advanced or Metastatic Gastric or Gastro-esophageal Junction (GEJ) AdenocarcinomaNot phased (device or behavioral study)CompletedJun 8, 2018Jun 9, 2020 (actual)
NCT03101267A Dose-finding Study of ASP4070Phase 2CompletedApr 13, 2017Jan 26, 2018 (actual)
NCT01371994A Study to Assess Efficacy and Safety With Solifenacin Succinate to Improve Urinary Continence After Robotic Assisted Radical ProstatectomyPhase 4CompletedAug 2, 2011Oct 21, 2013 (actual)
NCT00912964A Study to Test the Efficacy and Safety of the Beta-3 Agonist Mirabegron (YM178) in Patients With Symptoms of Overactive BladderPhase 3CompletedApr 28, 2009Apr 27, 2010 (actual)
NCT01284920A Study of MDV3100 to Evaluate Safety, Tolerability, Pharmacokinetics and Efficacy of in Prostate Cancer PatientsPhase 1/Phase 2CompletedNov 2, 2010Jul 12, 2012 (actual)
NCT02669771Long-Term Specified Drug Use-Results Survey for Xtandi CapsuleNot listedCompletedNov 30, 2014Nov 30, 2018 (actual)
NCT00514306Study of Intermittent OSI-906 DosingPhase 1CompletedJul 5, 2007Sep 20, 2010 (actual)
Feedback