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COMPANY

Barinthus Biotherapeutics

HQ: Germantown, MD source · barinthusbio.com ↗

Clinical Phase 2

Keywords: immunology inflammatory diseases Influenza Hepatitis B Celiac Disease Chronic Hepatitis B Prostate Cancer HPV Infection CIN1 VTP-1000 ChAdOx1-HBV

Location: Germantown, MD · source · Oct 14, 2026

Profile checked Oct 10, 2026

10Trials (company is sponsor)

Timeline

  1. Trial start Early phase 1: VTP-1000 in Adults With Celiac Disease source ↗
  2. Trial start Phase 1/Phase 2: Prime-boost Immunotherapeutic Trial in Men With Biochemical Recurrence After Definitive Local Therapy for Prostate Cancer source ↗
  3. Trial start Phase 2: Efficacy of VTP-300 in Chronic Hepatitis B Infection source ↗
  4. Trial start Phase 1/Phase 2: Prime-boost Vaccine Study in Women With Low-grade Cervical HPV Lesions source ↗
  5. Trial start Phase 1/Phase 2: First-In-Human Study of ChAdOx1-HBV & MVA-HBV Vaccines (VTP-300) for Chronic HBV source ↗
  6. Trial start Phase 2: Efficacy of MVA-NP+M1 in the Influenza H3N2 Human Challenge Model source ↗
  7. Trial start Phase 2: Efficacy of Candidate Influenza Vaccine MVA-NP+M1 in Adults source ↗
  8. Trial start Phase 1: First in Human Study of ChAdOx1-HBV in Healthy Participants and Participants With Chronic hepB Infection source ↗
  9. Trial start Phase 2: Improved Novel VaccIne CombinaTion InflUenza Study source ↗
  10. Trial start Early phase 1: A Study to Determine the Safety and Immunogenicity of the Candidate Influenza Vaccine MVA-NP+M1 source ↗

Upcoming milestones

Estimated primary completion per ClinicalTrials.gov. Dates move.

Clinical trials (lead sponsor) 10

RecordTitlePhaseStatusStartPrimary completion
NCT06310291VTP-1000 in Adults With Celiac DiseaseEarly phase 1RecruitingAug 1, 20242026-11 (estimated)
NCT05343481Efficacy of VTP-300 in Chronic Hepatitis B InfectionPhase 2CompletedSep 21, 2022Jan 13, 2026 (actual)
NCT05617040Prime-boost Immunotherapeutic Trial in Men With Biochemical Recurrence After Definitive Local Therapy for Prostate CancerPhase 1/Phase 2TerminatedJan 30, 2023Feb 5, 2025 (actual)
NCT04607850Prime-boost Vaccine Study in Women With Low-grade Cervical HPV LesionsPhase 1/Phase 2CompletedMar 16, 2021Jan 16, 2024 (actual)
NCT04297917First in Human Study of ChAdOx1-HBV in Healthy Participants and Participants With Chronic hepB InfectionPhase 1CompletedFeb 10, 2019May 23, 2022 (actual)
NCT04778904First-In-Human Study of ChAdOx1-HBV & MVA-HBV Vaccines (VTP-300) for Chronic HBVPhase 1/Phase 2CompletedDec 22, 2020Feb 24, 2023 (actual)
NCT03880474Efficacy of Candidate Influenza Vaccine MVA-NP+M1 in AdultsPhase 2TerminatedMar 18, 2019Oct 15, 2019 (actual)
NCT03883113Efficacy of MVA-NP+M1 in the Influenza H3N2 Human Challenge ModelPhase 2CompletedJun 3, 2019Dec 16, 2019 (actual)
NCT03300362Improved Novel VaccIne CombinaTion InflUenza StudyPhase 2TerminatedOct 13, 2017Oct 31, 2018 (actual)
NCT03277456A Study to Determine the Safety and Immunogenicity of the Candidate Influenza Vaccine MVA-NP+M1Early phase 1CompletedSep 18, 2017Nov 2, 2017 (actual)
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