COMPANY
PTC Therapeutics
FDA-approved therapeutic company Clinical Phase 3
Hiring
| Title | Location (from posting) | Employer posted | First seen |
|---|---|---|---|
| Senior Manager, Statistical Programming | 3 locations, including Warren, New Jersey, USA | Oct 22, 2026 | Oct 9, 2026 |
| Senior Manager, Global Clinical Regulatory Lead | USA - New Jersey - Warren | Oct 22, 2026 | Oct 9, 2026 |
| Marketing & Communications Manager | Tokyo | Oct 22, 2026 | Oct 21, 2026 |
| Associate Director, Clinical Operations | 8 locations, including Warren, New Jersey, USA | Oct 21, 2026 | Oct 9, 2026 |
| Senior Manager, Clinical Operations | 8 locations, including Warren, New Jersey, USA | Oct 21, 2026 | Oct 9, 2026 |
Timeline
- Board tracked Radar started tracking this company’s job board (43 open jobs at last check). source ↗
- Trial start Phase 2: Study of PTC844 in Participants With Active Rheumatoid Arthritis source ↗
- Trial start Phase 3: Long-Term Efficacy Study of Vatiquinone for the Treatment of Friedreich's Ataxia (FA) source ↗
- FDA FDA New drug/biologic (novel): SEPHIENCE (sepiapterin) — NDA219666, Jul 28, 2025. Applicant at approval: PTC Therapeutics, Inc. source ↗
- Partnership Partnership / licensing: $1B (upfront, as published); deal value up to $1.9B (kept separate from upfront), announced Dec 2, 2024. Source: SEC filing. source ↗
- FDA FDA New drug/biologic (novel): KEBILIDI (eladocagene exuparvovec-tneq) — BLA125722, Nov 13, 2024. Applicant at approval: PTC Therapeutics, Inc. source ↗
- Trial start Phase 3: A Study of Sepiapterin in Participants With Phenylketonuria (PKU) source ↗
- Trial start Phase 3: A Study to Assess the Safety and Efficacy of Vatiquinone in Participants With Friedreich Ataxia source ↗
- Trial start Phase 2: A Study of Vatiquinone for the Treatment of Participants With Friedreich Ataxia source ↗
- Trial start Phase 3: A Safety Study for Previously Treated Vatiquinone (PTC743) Participants With Inherited Mitochondrial Disease source ↗
- Trial start Phase 2/Phase 3: A Study of Unesbulin in Participants With Advanced Leiomyosarcoma (LMS) source ↗
- Trial start Phase 2: Study to Assess the Effects of PTC857 Treatment in Participants With Amyotrophic Lateral Sclerosis ALS source ↗
- Trial start Phase 3: A Long-Term Safety Study of PTC923 in Participants With Phenylketonuria source ↗
- Trial start Phase 2: A Study to Evaluate the Safety and Pharmacokinetics of Ataluren in Participants From ≥6 Months to <2 Years of Age With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD) source ↗
- Trial start Phase 3: A Study of PTC923 in Participants With Phenylketonuria source ↗
- Trial start Phase 2: A Study of SmartFlow Magnetic Resonance (MR) Compatible Ventricular Cannula for Administering Eladocagene Exuparvovec to Pediatric Participants source ↗
- Trial start Phase 2/Phase 3: A Study to Assess the Efficacy and Safety of Vatiquinone for the Treatment of Participants With Friedreich Ataxia source ↗
- Trial start Phase 2/Phase 3: A Study to Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy source ↗
- Trial start Phase 2/Phase 3: A Study to Evaluate Efficacy and Safety of PTC299 (Emvododstat) in Hospitalized Participants With Coronavirus (COVID-19) source ↗
- Trial start Phase 3: A Study of Deflazacort (Emflaza®) in Participants With Limb-Girdle Muscular Dystrophy 2I (LGMD2I) source ↗
- Trial start Phase 2: A Study to Assess Dystrophin Levels in Participants With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD) Who Have Been Treated With Ataluren source ↗
- Trial start Phase 1: A Study of Unesbulin (PTC596) in Combination With Dacarbazine in Participants With Advanced Leiomyosarcoma (LMS) source ↗
- Trial start Phase 2: A Study of CNSA-001 in Women With Diabetic Gastroparesis source ↗
- Trial start Phase 1/Phase 2: A Study of PTC923 (CNSA-001) in Primary Tetrahydrobiopterin (BH4) Deficient Participants With Hyperphenylalaninemia source ↗
- Trial start 2: A Phase 2 Open Label Extension Study in Participants With Nonsense Mutation Aniridia source ↗
Upcoming milestones
- Sep 30, 2027 (ESTIMATED) · Phase 2 · Study of PTC844 in Participants With Active Rheumatoid Arthritis · NCT07779616
- Dec 31, 2027 (ESTIMATED) · Phase 3 · A Study to Assess the Safety and Efficacy of Vatiquinone in Participants With Friedreich Ataxia · NCT05515536
- Mar 15, 2029 (ESTIMATED) · Phase 3 · Long-Term Efficacy Study of Vatiquinone for the Treatment of Friedreich's Ataxia (FA) · NCT07681713
- Feb 28, 2031 (ESTIMATED) · Phase 3 · A Study of Sepiapterin in Participants With Phenylketonuria (PKU) · NCT06302348
Open jobs 43
| Title | Location (from posting, not HQ) | Employer posted | First seen | Level |
|---|---|---|---|---|
| Senior Manager, Statistical Programming | 3 locations, including Warren, New Jersey, USA | Oct 22, 2026 | Oct 9, 2026 | Senior |
| Senior Manager, Global Clinical Regulatory Lead | USA - New Jersey - Warren | Oct 22, 2026 | Oct 9, 2026 | Senior |
| Marketing & Communications Manager | Tokyo | Oct 22, 2026 | Oct 21, 2026 | Not stated |
| Associate Director, Clinical Operations | 8 locations, including Warren, New Jersey, USA | Oct 21, 2026 | Oct 9, 2026 | Senior |
| Senior Manager, Clinical Operations | 8 locations, including Warren, New Jersey, USA | Oct 21, 2026 | Oct 9, 2026 | Senior |
| Senior Manager, Clinical Operations | 8 locations, including Warren, New Jersey, USA | Oct 20, 2026 | Oct 9, 2026 | Not stated |
| Patient Support Specialist - Bilingual (West Coast Candidates) | 3 locations (listed on the posting) | Oct 20, 2026 | Oct 21, 2026 | Not stated |
| Key Account Manager Japan | Japan (Remote) | Oct 20, 2026 | Oct 21, 2026 | Not stated |
| Contractor, Clinical Operations | USA - New Jersey - Warren | Oct 19, 2026 | Oct 9, 2026 | Not stated |
| Senior Manager, Biostatistics | USA - New Jersey - Warren | Oct 19, 2026 | Oct 20, 2026 | Not stated |
| Senior Manager, Manufacturing Science and Technology - Drug Product | Ireland - Dublin | Oct 16, 2026 | Oct 16, 2026 | Not stated |
| Associate Director, EU Data Protection Officer (DPO) | 2 locations, including Dublin, Ireland | Oct 14, 2026 | Oct 15, 2026 | Senior |
| Key Account Manager, Italy Central | Italy (Remote) | Oct 14, 2026 | Oct 15, 2026 | Mid |
| Key Account Manager, Italy South. | Italy (Remote) | Oct 14, 2026 | Oct 15, 2026 | Mid |
| MSL I - Doenças Raras (Nordeste, Centro-oeste ou São Paulo) | 2 locations (listed on the posting) | Oct 13, 2026 | Oct 14, 2026 | Mid |
| Senior Director, Biostatistics | USA - New Jersey - Warren | Oct 12, 2026 | Oct 14, 2026 | Senior |
| Director, Global Compensation and Equity | USA - New Jersey - Warren | Oct 9, 2026 | Oct 9, 2026 | Senior |
| Manager, Total Rewards | Ireland - Dublin | Oct 9, 2026 | Oct 9, 2026 | Senior |
| Contractor, Drug Metabolism and Pharmacokinetics (DMPK) | USA - New Jersey - Bridgewater | Oct 8, 2026 | Oct 9, 2026 | Mid |
| Associate Director, Pharmacovigilance - Safety Scientist | 3 locations, including Guildford, United Kingdom | Oct 8, 2026 | Oct 9, 2026 | Senior |
| Contractor, Accounting Analyst | Brazil - Sao Paulo | Oct 7, 2026 | Oct 9, 2026 | Mid |
| Regional Account Manager-Eastern Midwest Region | Remote (United States) | Oct 7, 2026 | Oct 9, 2026 | Mid |
| Regional Account Manager -Northeast/Eastern Region | Not listed | Oct 7, 2026 | Oct 9, 2026 | Mid |
| Contractor, GxP Bioanalytical Scientist, Clinical Pharmacology | USA - New Jersey - Pennington | Oct 6, 2026 | Oct 9, 2026 | Entry |
| Senior Director, Clinical Development | 9 locations, including Warren, New Jersey, USA | Oct 5, 2026 | Oct 9, 2026 | Senior |
| Director, Clinical Development | 9 locations, including Warren, New Jersey, USA | Oct 5, 2026 | Oct 9, 2026 | Senior |
| Contractor, Clinical Data Management | USA - New Jersey - Warren | Oct 1, 2026 | Oct 9, 2026 | Senior |
| Associate Director, Manufacturing Science and Technology – Drug Product | USA - New Jersey - Warren | Sep 30, 2026 | Oct 9, 2026 | Senior |
| Regional Account Manager - Upstate NY | Remote(US-New York) | Sep 30, 2026 | Oct 9, 2026 | Mid |
| Director, Project Management | USA - New Jersey - Warren | Sep 29, 2026 | Oct 9, 2026 | Senior |
| Senior Manager, Clinical Data Management | USA - New Jersey - Warren | Sep 29, 2026 | Oct 9, 2026 | Senior |
| Medical Science Liaison - Metabolic (Mid Atlantic) | 7 locations (listed on the posting) | Sep 28, 2026 | Oct 9, 2026 | Entry |
| Contractor, Global Medical Affairs Operations | USA - New Jersey - Warren | Sep 24, 2026 | Oct 9, 2026 | Mid |
| Patient Engagement Liaison (Midwest) | 4 locations (listed on the posting) | Sep 24, 2026 | Oct 9, 2026 | Mid |
| Patient Engagement Liaison (Mid-Atlantic/Ohio Valley) | 4 locations (listed on the posting) | Sep 24, 2026 | Oct 9, 2026 | Mid |
| Associate Director, Clinical Supplies | USA - New Jersey - Warren | Sep 23, 2026 | Oct 9, 2026 | Senior |
| Medical Value Director | Remote (United States) | Sep 23, 2026 | Oct 9, 2026 | Senior |
| Senior Scientist, Analytical Development | USA - New Jersey - Bridgewater | Sep 23, 2026 | Oct 9, 2026 | Senior |
| Medical Science Liaison | France - Paris | Sep 23, 2026 | Oct 9, 2026 | Senior |
| Associate Director, Regulatory Affairs - CMC | Not listed | Sep 23, 2026 | Oct 9, 2026 | Senior |
| Associate Manager, Financial Planning & Analysis -Commercial Functions | USA - New Jersey - Warren | Sep 23, 2026 | Oct 9, 2026 | Mid |
| Director, Clinical Data Management | USA - New Jersey - Warren | Sep 23, 2026 | Oct 9, 2026 | Senior |
| Associate Director, Clinical Data Management | USA - New Jersey - Warren | Sep 23, 2026 | Oct 9, 2026 | Senior |
Funding
- Partnership / licensing: $1B (upfront, as published); deal value up to $1.9B (kept separate from upfront), announced Dec 2, 2024. Source: SEC filing. source ↗
Clinical trials (lead sponsor) Showing 50 of 65
| Record | Title | Phase | Status | Start | Primary completion |
|---|---|---|---|---|---|
| NCT01247207 | Study of Ataluren in Previously Treated Participants With Nonsense Mutation Dystrophinopathy (nmDBMD) | Phase 3 | Terminated | Nov 22, 2010 | Feb 10, 2026 (actual) |
| NCT05166161 | A Long-Term Safety Study of PTC923 in Participants With Phenylketonuria | Phase 3 | Completed | Feb 14, 2022 | Jul 21, 2026 (actual) |
| NCT06302348 | A Study of Sepiapterin in Participants With Phenylketonuria (PKU) | Phase 3 | Recruiting | Mar 4, 2024 | Feb 28, 2031 (estimated) |
| NCT07779616 | Study of PTC844 in Participants With Active Rheumatoid Arthritis | Phase 2 | Not yet recruiting | Aug 31, 2026 | Sep 30, 2027 (estimated) |
| NCT07681713 | Long-Term Efficacy Study of Vatiquinone for the Treatment of Friedreich's Ataxia (FA) | Phase 3 | Not yet recruiting | Aug 15, 2026 | Mar 15, 2029 (estimated) |
| NCT04903288 | A Study of SmartFlow Magnetic Resonance (MR) Compatible Ventricular Cannula for Administering Eladocagene Exuparvovec to Pediatric Participants | Phase 2 | Active, not recruiting | May 12, 2021 | May 22, 2023 (actual) |
| NCT04577352 | A Study to Assess the Efficacy and Safety of Vatiquinone for the Treatment of Participants With Friedreich Ataxia | Phase 2/Phase 3 | Completed | Dec 17, 2020 | Apr 4, 2023 (actual) |
| NCT04378075 | A Study to Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy | Phase 2/Phase 3 | Terminated | Sep 28, 2020 | Mar 18, 2023 (actual) |
| NCT03179631 | Long-Term Outcomes of Ataluren in Duchenne Muscular Dystrophy | Phase 3 | Completed | Jul 6, 2017 | Mar 5, 2022 (actual) |
| NCT02369731 | Registry of Translarna (Ataluren) in Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD) | Not listed | Completed | Apr 30, 2015 | Mar 31, 2025 (actual) |
| NCT05218655 | A Safety Study for Previously Treated Vatiquinone (PTC743) Participants With Inherited Mitochondrial Disease | Phase 3 | Completed | Jun 22, 2022 | Apr 15, 2025 (actual) |
| NCT05515536 | A Study to Assess the Safety and Efficacy of Vatiquinone in Participants With Friedreich Ataxia | Phase 3 | Active, not recruiting | Dec 8, 2022 | Dec 31, 2027 (estimated) |
| NCT05485987 | A Study of Vatiquinone for the Treatment of Participants With Friedreich Ataxia | Phase 2 | Completed | Oct 12, 2022 | Aug 29, 2024 (actual) |
| NCT05349721 | Study to Assess the Effects of PTC857 Treatment in Participants With Amyotrophic Lateral Sclerosis ALS | Phase 2 | Terminated | May 15, 2022 | Sep 26, 2024 (actual) |
| NCT05269355 | A Study of Unesbulin in Participants With Advanced Leiomyosarcoma (LMS) | Phase 2/Phase 3 | Terminated | May 23, 2022 | Jun 17, 2024 (actual) |
| NCT02352896 | Long-Term Safety and Efficacy Evaluation of EPI-743 in Children With Leigh Syndrome | Phase 2 | Completed | Jan 31, 2014 | Oct 30, 2023 (actual) |
| NCT04336826 | A Study to Evaluate the Safety and Pharmacokinetics of Ataluren in Participants From ≥6 Months to <2 Years of Age With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD) | Phase 2 | Completed | Dec 29, 2021 | Aug 7, 2023 (actual) |
| NCT03761095 | A Study of Unesbulin (PTC596) in Combination With Dacarbazine in Participants With Advanced Leiomyosarcoma (LMS) | Phase 1 | Completed | Mar 13, 2019 | Feb 5, 2024 (actual) |
| NCT01370447 | EPI-743 for Mitochondrial Respiratory Chain Diseases | Not listed | No longer available | Not listed | Not listed |
| NCT05099640 | A Study of PTC923 in Participants With Phenylketonuria | Phase 3 | Completed | Sep 30, 2021 | Apr 3, 2023 (actual) |
| NCT03519711 | A Study of PTC923 (CNSA-001) in Primary Tetrahydrobiopterin (BH4) Deficient Participants With Hyperphenylalaninemia | Phase 1/Phase 2 | Completed | Jan 3, 2019 | Oct 2, 2020 (actual) |
| NCT04439071 | A Study to Evaluate Efficacy and Safety of PTC299 (Emvododstat) in Hospitalized Participants With Coronavirus (COVID-19) | Phase 2/Phase 3 | Terminated | Jul 9, 2020 | Jul 20, 2022 (actual) |
| NCT03783923 | A Study of Deflazacort (Emflaza®) in Participants With Limb-Girdle Muscular Dystrophy 2I (LGMD2I) | Phase 3 | Terminated | Oct 31, 2019 | Jan 1, 2021 (actual) |
| NCT02647359 | Study of Ataluren in Participants With Nonsense Mutation Aniridia | Phase 2 | Completed | Jan 31, 2016 | Jan 22, 2021 (actual) |
| NCT03796637 | A Study to Assess Dystrophin Levels in Participants With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD) Who Have Been Treated With Ataluren | Phase 2 | Completed | Apr 11, 2019 | Jun 3, 2019 (actual) |
| NCT03648827 | A Study to Assess Dystrophin Levels in Participants With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD) | Phase 2 | Completed | Dec 21, 2018 | Oct 23, 2020 (actual) |
| NCT03761069 | Study of PTC299 (Emvododstat) in Relapsed/Refractory Acute Leukemias | Phase 1 | Terminated | Oct 29, 2018 | Dec 28, 2021 (actual) |
| NCT03712124 | A Study of CNSA-001 in Women With Diabetic Gastroparesis | Phase 2 | Completed | Feb 27, 2019 | Sep 8, 2019 (actual) |
| NCT01557400 | Study of Ataluren for Previously Treated Participants With Nonsense Mutation Duchenne/Becker Muscular Dystrophy (nmDBMD) in Europe, Israel, Australia, and Canada | Phase 3 | Completed | May 20, 2012 | Jan 19, 2018 (actual) |
| NCT00759876 | Phase 2a Extension Study of Ataluren (PTC124) in Duchenne Muscular Dystrophy (DMD) | 2 | Terminated | Aug 13, 2008 | May 17, 2010 (actual) |
| NCT01140451 | Extension Study of Ataluren (PTC124) in Cystic Fibrosis | Phase 3 | Completed | Aug 12, 2010 | Dec 2, 2013 (actual) |
| NCT02460679 | Safety and Biomarker Study of EPI-589 in Participants With Amyotrophic Lateral Sclerosis (ALS) | Phase 2 | Completed | Jan 14, 2016 | Feb 23, 2018 (actual) |
| NCT01721733 | Safety and Efficacy Study of EPI-743 in Children With Leigh Syndrome | Phase 2 | Completed | Oct 31, 2012 | Feb 28, 2015 (actual) |
| NCT01728064 | Safety and Efficacy of EPI-743 in Patients With Friedreich's Ataxia | Phase 2 | Completed | Dec 31, 2012 | Oct 31, 2015 (actual) |
| NCT02819557 | Study of Ataluren in ≥2 to <5 Year-Old Male Participants With Duchenne Muscular Dystrophy | Phase 2 | Completed | Jun 9, 2016 | Feb 9, 2018 (actual) |
| NCT02090959 | An Extension Study of Ataluren (PTC124) in Participants With Nonsense Mutation Dystrophinopathy | Phase 3 | Terminated | Mar 20, 2014 | Jun 12, 2018 (actual) |
| NCT01826487 | Phase 3 Study of Ataluren in Participants With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD) | 3 | Completed | Mar 26, 2013 | Aug 20, 2015 (actual) |
| NCT01009294 | Study of Ataluren (PTC124) in Nonambulatory Participants With Nonsense-Mutation-Mediated Duchenne/Becker Muscular Dystrophy (nmDMD/BMD) | Phase 2 | Terminated | Jan 13, 2010 | Mar 23, 2010 (actual) |
| NCT00847379 | Phase 2B Extension Study of Ataluren (PTC124) in Duchenne/Becker Muscular Dystrophy (DMD/BMD) | 2B | Terminated | Jan 31, 2009 | May 24, 2010 (actual) |
| NCT01141075 | Ataluren for Nonsense Mutation Methylmalonic Acidemia | Phase 2 | Terminated | Jul 19, 2010 | Nov 3, 2011 (actual) |
| NCT00947193 | Study of Ataluren (PTC124) in Hemophilia A and B | Phase 2 | Terminated | Oct 14, 2009 | Aug 30, 2011 (actual) |
| NCT00237380 | Safety and Efficacy of Ataluren (PTC124) for Cystic Fibrosis | Phase 2 | Completed | Nov 30, 2005 | May 31, 2006 (actual) |
| NCT00803205 | Study of Ataluren (PTC124™) in Cystic Fibrosis | Phase 3 | Completed | Sep 8, 2009 | Nov 12, 2011 (actual) |
| NCT02139306 | Study of Ataluren in Nonsense Mutation Cystic Fibrosis (ACT CF) | Phase 3 | Completed | 2014-08 | 2016-11 (actual) |
| NCT02456103 | Extension Study of Ataluren in Participants With Nonsense Mutation Cystic Fibrosis | Phase 3 | Terminated | Aug 31, 2015 | Jun 2, 2017 (actual) |
| NCT00592553 | Phase 2B Study of PTC124 (Ataluren) in Duchenne/Becker Muscular Dystrophy (DMD/BMD) | 2B | Completed | Feb 29, 2008 | Dec 31, 2009 (actual) |
| NCT02107859 | Study of Ataluren (PTC124) in Cystic Fibrosis | Phase 3 | Terminated | May 23, 2014 | Jun 5, 2017 (actual) |
| NCT00458341 | A Study of Ataluren in Pediatric Participants With Cystic Fibrosis | Phase 2 | Completed | Mar 23, 2007 | Feb 29, 2008 (actual) |
| NCT04117880 | A Phase 2 Open Label Extension Study in Participants With Nonsense Mutation Aniridia | 2 | Withdrawn | Dec 31, 2018 | Jan 31, 2021 (estimated) |
| NCT03642145 | A Study of Deflazacort (Emflaza®) in Participants With Duchenne Muscular Dystrophy (DMD) | Phase 3 | Withdrawn | Oct 31, 2018 | Jul 31, 2021 (estimated) |
FDA records (last 2 years)
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