COMPANY
Humacyte
FDA-approved therapeutic company Clinical Phase 3
Hiring
| Title | Location (from posting) | Employer posted | First seen |
|---|---|---|---|
| Maintenance Engineer | North Carolina, Durham, NC, US | Oct 22, 2026 | Oct 11, 2026 |
| Senior Mechanical Technician | North Carolina, Durham, NC, US | Oct 22, 2026 | Oct 11, 2026 |
| Warehouse Logistics Associate I | North Carolina, Durham, NC, US | Oct 21, 2026 | Oct 22, 2026 |
| (Sr.) Manager, Marketing Communications & DTC | Remote, US | Oct 21, 2026 | Oct 21, 2026 |
| MSAT Engineer II | North Carolina, Durham, NC, US | Oct 16, 2026 | Oct 16, 2026 |
Timeline
- Trial start Phase 4: Multicenter Study to Evaluate the Safety and Efficacy of SYMVESS™ in a Real World Setting in Patients With Extremity Arterial Injury Requiring Urgent Repair source ↗
- Trial start Phase 3: An Open-label Study to Assess the Safety and Efficacy of SYMVESS® as a Vascular Conduit in Adolescents With Extremity Arterial Injury. source ↗
- Trial start Phase 2: Study to Evaluate the Safety and Efficacy of Humacyte's Coronary Tissue Engineered Vessel (CTEV) in Patients With Coronary Artery Disease Requiring Coronary Artery Bypass Grafting (CABG) source ↗
- Raise Follow-on offering: $50M (total, as published), announced Jun 10, 2026. Source: SEC filing. source ↗
- Raise Follow-on offering — Registered direct: $20M (total, as published), announced Mar 19, 2026. Source: SEC filing. source ↗
- Debt Debt financing: $77.5M (up to, as announced), announced Dec 16, 2025. Source: company release on GlobeNewswire. source ↗
- Raise Follow-on offering — Registered direct: $60M (total, as published), announced Oct 7, 2025. Source: company release on GlobeNewswire. source ↗
- Raise Follow-on offering: $50M (total, as published), announced Mar 26, 2025. Source: company release on GlobeNewswire. source ↗
- FDA FDA New drug/biologic (novel): symvess (acellular tissue engineered vessel-tyod) — BLA125812, Dec 19, 2024. Applicant at approval: Humacyte Global, Inc. source ↗
- Raise Follow-on offering — Registered direct: $15M (total, as published), announced Nov 14, 2024. Source: company release on GlobeNewswire. source ↗
- Trial start Phase 3: To Compare the Efficacy and Safety of the ATEV With AVF in Female Patients With End-Stage Renal Disease Requiring Hemodialysis source ↗
- Trial start —: An Observational Study to Evaluate the Safety and Efficacy of Humacyte's HAV for Arterial Replacement or Reconstruction in Ukrainian Patients With Life or Limb-threatening Vascular Trauma source ↗
- Trial start Phase 2: Safety and Efficacy Assessment of HAV in Patients Needing Vascular Access for Dialysis source ↗
- Trial start Phase 2/Phase 3: Humacyte Acellular Tissue Engineered Vessel (ATEV) in Patients With Vascular Trauma source ↗
- Trial start Phase 3: Comparison of the Human Acellular Vessel (HAV) With Fistulas as Conduits for Hemodialysis source ↗
- Trial start Phase 2: Humacyte's HAV for Femoro-Popliteal Bypass in Patients With PAD source ↗
- Trial start Phase 3: Comparison of the Human Acellular Vessel (HAV) With ePTFE Grafts as Conduits for Hemodialysis source ↗
- Trial start Not phased (device or behavioral study): Evaluation of the Safety and Efficacy of a Vascular Prosthesis as an Above-Knee Bypass Graft in Patients With PAD source ↗
- Trial start Phase 1: Safety and Efficacy of a Vascular Prosthesis for Hemodialysis Access in Patients With End-Stage Renal Disease source ↗
- Trial start Not phased (device or behavioral study): Evaluation of the Safety and Efficacy of a Vascular Prosthesis for Hemodialysis Access in Patients With ESRD source ↗
Upcoming milestones
- 2027-06 (ESTIMATED) · Phase 3 · To Compare the Efficacy and Safety of the ATEV With AVF in Female Patients With End-Stage Renal Disease Requiring Hemodialysis · NCT05908084
- 2028-12 (ESTIMATED) · Phase 3 · An Open-label Study to Assess the Safety and Efficacy of SYMVESS® as a Vascular Conduit in Adolescents With Extremity Arterial Injury. · NCT07762313
- 2030-09 (ESTIMATED) · Phase 4 · Multicenter Study to Evaluate the Safety and Efficacy of SYMVESS™ in a Real World Setting in Patients With Extremity Arterial Injury Requiring Urgent Repair · NCT07762794
- 2030-09 (ESTIMATED) · Phase 2 · Study to Evaluate the Safety and Efficacy of Humacyte's Coronary Tissue Engineered Vessel (CTEV) in Patients With Coronary Artery Disease Requiring Coronary Artery Bypass Grafting (CABG) · NCT07730528
Funding
- Follow-on offering: $50M (total, as published), announced Jun 10, 2026. Source: SEC filing. source ↗
- Follow-on offering — Registered direct: $20M (total, as published), announced Mar 19, 2026. Source: SEC filing. source ↗
- Follow-on offering — Registered direct: $60M (total, as published), announced Oct 7, 2025. Source: company release on GlobeNewswire. source ↗
- Follow-on offering: $50M (total, as published), announced Mar 26, 2025. Source: company release on GlobeNewswire. source ↗
- Follow-on offering — Registered direct: $15M (total, as published), announced Nov 14, 2024. Source: company release on GlobeNewswire. source ↗
- Debt financing: $77.5M (up to, as announced), announced Dec 16, 2025. Source: company release on GlobeNewswire. source ↗
Clinical trials (lead sponsor) 15
| Record | Title | Phase | Status | Start | Primary completion |
|---|---|---|---|---|---|
| NCT07141641 | Individual Patient Expanded Access for Acellular Tissue Engineered Vessel (ATEV) for Vascular Disease and Dialysis Access | Not listed | Temporarily not available | Not listed | Not listed |
| NCT02644941 | Comparison of the Human Acellular Vessel (HAV) With ePTFE Grafts as Conduits for Hemodialysis | Phase 3 | Completed | May 24, 2016 | 2019-05 (actual) |
| NCT07762794 | Multicenter Study to Evaluate the Safety and Efficacy of SYMVESS™ in a Real World Setting in Patients With Extremity Arterial Injury Requiring Urgent Repair | Phase 4 | Not yet recruiting | 2026-09 | 2030-09 (estimated) |
| NCT07762313 | An Open-label Study to Assess the Safety and Efficacy of SYMVESS® as a Vascular Conduit in Adolescents With Extremity Arterial Injury. | Phase 3 | Not yet recruiting | 2026-09 | 2028-12 (estimated) |
| NCT03005418 | Humacyte Acellular Tissue Engineered Vessel (ATEV) in Patients With Vascular Trauma | Phase 2/Phase 3 | Completed | Sep 1, 2018 | Sep 19, 2023 (actual) |
| NCT07730528 | Study to Evaluate the Safety and Efficacy of Humacyte's Coronary Tissue Engineered Vessel (CTEV) in Patients With Coronary Artery Disease Requiring Coronary Artery Bypass Grafting (CABG) | Phase 2 | Not yet recruiting | 2026-09 | 2030-09 (estimated) |
| NCT05908084 | To Compare the Efficacy and Safety of the ATEV With AVF in Female Patients With End-Stage Renal Disease Requiring Hemodialysis | Phase 3 | Active, not recruiting | Sep 7, 2023 | 2027-06 (estimated) |
| NCT03183245 | Comparison of the Human Acellular Vessel (HAV) With Fistulas as Conduits for Hemodialysis | Phase 3 | Completed | Sep 29, 2017 | Apr 22, 2024 (actual) |
| NCT03631056 | Individual Patient Expanded Access for Acellular Tissue Engineered Vessel (ATEV) for Vascular System Injuries | Not listed | Approved for marketing | Not listed | Not listed |
| NCT02887859 | Humacyte's HAV for Femoro-Popliteal Bypass in Patients With PAD | Phase 2 | Completed | Dec 20, 2016 | 2020-12 (actual) |
| NCT05873959 | An Observational Study to Evaluate the Safety and Efficacy of Humacyte's HAV for Arterial Replacement or Reconstruction in Ukrainian Patients With Life or Limb-threatening Vascular Trauma | Not listed | Completed | May 1, 2023 | May 26, 2023 (actual) |
| NCT01872208 | Evaluation of the Safety and Efficacy of a Vascular Prosthesis as an Above-Knee Bypass Graft in Patients With PAD | Not phased (device or behavioral study) | Completed | Oct 10, 2013 | May 30, 2016 (actual) |
| NCT01744418 | Evaluation of the Safety and Efficacy of a Vascular Prosthesis for Hemodialysis Access in Patients With ESRD | Not phased (device or behavioral study) | Completed | Nov 22, 2012 | 2014-12 (actual) |
| NCT04135417 | Safety and Efficacy Assessment of HAV in Patients Needing Vascular Access for Dialysis | Phase 2 | Completed | Nov 12, 2019 | May 15, 2021 (actual) |
| NCT01840956 | Safety and Efficacy of a Vascular Prosthesis for Hemodialysis Access in Patients With End-Stage Renal Disease | Phase 1 | Completed | May 23, 2013 | Apr 28, 2016 (actual) |
FDA records (last 2 years)
- FDA New drug/biologic (novel): symvess (acellular tissue engineered vessel-tyod) — BLA125812, Dec 19, 2024. Applicant at approval: Humacyte Global, Inc. source ↗
NIH awards 10
- NIH contract (government contract; not a grant and not an investment round) 268201400011C-3-0-1 FY2016: $478,270 awarded for that fiscal year; activity N01 (OTHER_NIH); PI CONTE, MICHAEL; recipient as written: HUMACYTE, INC., RESEARCH TRIANGLE PARK, NC. IGF::O source ↗
- NIH award 5R44HL118736-06 FY2015: $967,567 awarded for that fiscal year; activity R44 (SBIR); PI LITHGOW, TED; recipient as written: HUMACYTE, INC., RESEARCH TRIANGLE PARK, NC. Novel Manufacturing Processes for Tissu source ↗
- NIH contract (government contract; not a grant and not an investment round) 268201400011C-2-0-1 FY2015: $566,202 awarded for that fiscal year; activity N01 (OTHER_NIH); PI CONTE, MICHAEL; recipient as written: HUMACYTE, INC., RESEARCH TRIANGLE PARK, NC. IGF::O source ↗
- NIH award 5R44HL118736-05 FY2014: $981,567 awarded for that fiscal year; activity R44 (SBIR); PI LITHGOW, TED; recipient as written: HUMACYTE, INC., RESEARCH TRIANGLE PARK, NC. Novel Manufacturing Processes for Tissu source ↗
- NIH award 1R43HL123169-01 FY2014: $217,277 awarded for that fiscal year; activity R43 (SBIR); PI KIRKTON, ROBERT DAVID; recipient as written: HUMACYTE, INC., RESEARCH TRIANGLE PARK, NC. Thromboresistant Small Diamete source ↗
- NIH contract (government contract; not a grant and not an investment round) 268201400011C-0-0-1 FY2014: $526,284 awarded for that fiscal year; activity N01 (OTHER_NIH); PI CONTE, MICHAEL; recipient as written: HUMACYTE, INC., RESEARCH TRIANGLE PARK, NC. IGF::O source ↗
- NIH award 9R44HL118736-04 FY2013: $998,367 awarded for that fiscal year; activity R44 (SBIR); PI DAHL, SHANNON L. M.; recipient as written: HUMACYTE, INC., RESEARCH TRIANGLE PARK, NC. Novel Manufacturing Processes fo source ↗
- NIH award 5R44DK085760-03 FY2012: $592,354 awarded for that fiscal year; activity R44 (SBIR); PI DAHL, SHANNON L. M.; recipient as written: HUMACYTE, INC., RESEARCH TRIANGLE PARK, NC. Novel Manufacturing Processes fo source ↗
- NIH award 2R44DK085760-02 FY2011: $597,466 awarded for that fiscal year; activity R44 (SBIR); PI DAHL, SHANNON L. M.; recipient as written: HUMACYTE, INC., RESEARCH TRIANGLE PARK, NC. Novel Manufacturing Processes fo source ↗
- NIH award 1R43DK085760-01 FY2010: $236,549 awarded for that fiscal year; activity R43 (SBIR); PI DAHL, SHANNON L. M.; recipient as written: HUMACYTE, INC., RESEARCH TRIANGLE PARK, NC. Novel Manufacturing Processes fo source ↗
Open jobs 12
| Title | Location (from posting, not HQ) | Employer posted | First seen | Level |
|---|---|---|---|---|
| Maintenance Engineer | North Carolina, Durham, NC, US | Oct 22, 2026 | Oct 11, 2026 | Mid |
| Senior Mechanical Technician | North Carolina, Durham, NC, US | Oct 22, 2026 | Oct 11, 2026 | Senior |
| Warehouse Logistics Associate I | North Carolina, Durham, NC, US | Oct 21, 2026 | Oct 22, 2026 | Not stated |
| (Sr.) Manager, Marketing Communications & DTC | Remote, US | Oct 21, 2026 | Oct 21, 2026 | Not stated |
| MSAT Engineer II | North Carolina, Durham, NC, US | Oct 16, 2026 | Oct 16, 2026 | Not stated |
| Senior Quality Specialist - QMS & Doc Control | North Carolina, Durham, NC, US | Oct 15, 2026 | Oct 16, 2026 | Not stated |
| Supplier Quality Specialist | North Carolina, Durham, NC, US | Oct 13, 2026 | Oct 14, 2026 | Mid |
| Medical Science Liaison | Remote, US; Minneapolis; Milwaukee; Detroit; Chicago | Oct 8, 2026 | Oct 11, 2026 | Mid |
| Senior Demand Planner | Durham, NC, US | Oct 8, 2026 | Oct 11, 2026 | Senior |
| Manager, Instrumentation & Metrology | North Carolina, Durham, NC, US | Sep 15, 2026 | Oct 11, 2026 | Mid |
| Surgical Sales Executive - Northeast | Massachusetts, Boston, MA, US; Connecticut, New Haven, CT, US; Maine, Portland, ME, US; New York, NY, US; Remote, US | Sep 15, 2026 | Oct 11, 2026 | Mid |
| Surgical Sales Executive- Chicago/Minneapolis | Remote, US; Minneapolis; Chicago | Sep 15, 2026 | Oct 11, 2026 | Mid |
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