COMPANY

Endologix

Profile checked Oct 10, 2026

Keywords: Peripheral Arterial Disease Abdominal Aortic Aneurysm AAA - Abdominal Aortic Aneurysm Abdominal Aortic Aneurysm Without Rupture Symptomatic Femoropopliteal Lesions Safety and Performance of the Nellix Endovascular Sealing System 1 Paravisceral Abdominal Aortic Aneurysm 2 Juxtarenal Abdominal Aortic Aneurysm 3 Pararenal Abdominal Aortic Aneurysm 4 Complex Abdominal Aortic Aneurysms Peripheral Artery Diseases Juxtarenal Aortic Aneurysm Pararenal Aortic Aneurysm DETOUR System Nellix Endovascular Aneurysm Sealing System PQ Bypass System for Femoropopliteal Bypass Nellix® System AFX2 System Chimney Endovascular Aortic Sealing (ChEVAS) System Nellix System PQ Bypass System PQ Bypass Guide Wire Delivery System The Nellix® EndoVascular Aneurysm Sealing System

25Trials (company is sponsor)

Timeline

2025-12 Trial start Not phased (device or behavioral study): JAGUAR Trial (Outside United States; OUS): ObJective Analysis to GaUge EVAR Outcomes Through Randomization source ↗
Oct 6, 2023 Trial start —: The Percutaneous Transmural Arterial Bypass -1 Study (Post Approval Registry) source ↗
Sep 21, 2023 Trial start —: The Long-Term EVAR Assessment and Follow-Up (LEAF) Study for the AFX2 System source ↗
Sep 20, 2021 Trial start Not phased (device or behavioral study): JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization source ↗
Apr 7, 2021 Trial start Not phased (device or behavioral study): Detour2 Continued Access Study source ↗
Jun 29, 2020 Trial start Not phased (device or behavioral study): Chimney EndoVascular Aneurysm Sealing Of New Expanded Indication source ↗
Aug 13, 2018 Trial start Not phased (device or behavioral study): The PQ Bypass Pivotal IDE Intra-arterial Stent Graft Study source ↗
Dec 13, 2017 Trial start Not phased (device or behavioral study): The DETOUR 2 Clinical Trial source ↗
Dec 1, 2017 Trial start Not phased (device or behavioral study): EVAS2 IDE Prospective, Multicenter, Single Arm Safety and Effectiveness Confirmatory Study source ↗
Mar 30, 2017 Trial start Not phased (device or behavioral study): Expanding Patient Applicability With Polymer Sealing Ovation Alto Stent Graft Investigational Device Exemption (IDE) Study source ↗
2016-11 Trial start —: Nellix Registry Study: EVAS-Global source ↗
2016-02 Trial start Not phased (device or behavioral study): TORUS I Clinical Study source ↗
2015-03 Trial start Not phased (device or behavioral study): Post-Market Study to Assess Outcomes of Patients Treated With AFX System Compared to Other EVAR Devices source ↗
2015-01 Trial start Not phased (device or behavioral study): DETOUR I Clinical Study for Percutaneous Femoropopliteal Bypass source ↗
2013-12 Trial start Not phased (device or behavioral study): Safety and Effectiveness Study of Endovascular Abdominal Aortic Aneurysm Repair Using the Nellix® System source ↗
2013-11 Trial start Not phased (device or behavioral study): PQ Bypass Guide Wire Delivery System for Femoropopliteal Bypass source ↗
2013-10 Trial start —: Nellix® Registry Study: EVAS-Global source ↗
Mar 3, 2013 Trial start Not phased (device or behavioral study): Safety and Effectiveness Trial of the Ventana Fenestrated Stent Graft System source ↗
Oct 19, 2011 Trial start Not phased (device or behavioral study): Feasibility and Safety Study of the Endologix Fenestrated Stent Graft System source ↗
Nov 2, 2010 Trial start Not phased (device or behavioral study): Pilot Study of the Endologix Fenestrated Stent Graft System source ↗
Apr 13, 2010 Trial start Not phased (device or behavioral study): Percutaneous Endovascular Aneurysm Repair (PEVAR) Trial source ↗
2008-12 Trial start Not phased (device or behavioral study): The Nellix® EndoVascular Aneurysm Sealing System for the Treatment of Infrarenal Abdominal Aortic Aneurysms source ↗
Aug 10, 2007 Trial start Not phased (device or behavioral study): 34mm Cuff Study for Endovascular Repair of Abdominal Aortic Aneurysms source ↗
May 5, 2006 Trial start Not phased (device or behavioral study): Suprarenal Proximal Cuff Study for Treatment of Abdominal Aortic Aneurysm source ↗
2005-10 Trial start Not phased (device or behavioral study): Powerlink Bifurcated Stent Graft Long-Term Follow-up Study source ↗

Upcoming milestones

2027-05 (ESTIMATED) · · The Long-Term EVAR Assessment and Follow-Up (LEAF) Study for the AFX2 System · NCT06990048
Jun 7, 2028 (ESTIMATED) · · The Percutaneous Transmural Arterial Bypass -1 Study (Post Approval Registry) · NCT06315023
2032-03 (ESTIMATED) · Not phased · JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization · NCT05064540

Estimated primary completion per ClinicalTrials.gov. Dates move.

Clinical trials (lead sponsor) 25

Record	Title	Phase	Status	Start	Primary completion
NCT05064540	JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization	Not phased (device or behavioral study)	Recruiting	Sep 20, 2021	2032-03 (estimated)
NCT04130737	The PQ Bypass Pivotal IDE Intra-arterial Stent Graft Study	Not phased (device or behavioral study)	Completed	Aug 13, 2018	Jan 6, 2023 (actual)
NCT02996396	Nellix Registry Study: EVAS-Global	Not listed	Completed	2016-11	Apr 25, 2023 (actual)
NCT02471638	DETOUR I Clinical Study for Percutaneous Femoropopliteal Bypass	Not phased (device or behavioral study)	Completed	2015-01	2018-09 (actual)
NCT03298477	EVAS2 IDE Prospective, Multicenter, Single Arm Safety and Effectiveness Confirmatory Study	Not phased (device or behavioral study)	Completed	Dec 1, 2017	Jun 7, 2022 (actual)
NCT06990048	The Long-Term EVAR Assessment and Follow-Up (LEAF) Study for the AFX2 System	Not listed	Active, not recruiting	Sep 21, 2023	2027-05 (estimated)
NCT06315023	The Percutaneous Transmural Arterial Bypass -1 Study (Post Approval Registry)	Not listed	Enrolling by invitation	Oct 6, 2023	Jun 7, 2028 (estimated)
NCT02018744	Nellix® Registry Study: EVAS-Global	Not listed	Completed	2013-10	2019-09 (actual)
NCT04252573	Chimney EndoVascular Aneurysm Sealing Of New Expanded Indication	Not phased (device or behavioral study)	Active, not recruiting	Jun 29, 2020	Oct 19, 2022 (actual)
NCT03128424	TORUS I Clinical Study	Not phased (device or behavioral study)	Completed	2016-02	2020-07 (actual)
NCT05409118	JAGUAR Trial (Outside United States; OUS): ObJective Analysis to GaUge EVAR Outcomes Through Randomization	Not phased (device or behavioral study)	Withdrawn	2025-12	2030-12 (estimated)
NCT03119233	The DETOUR 2 Clinical Trial	Not phased (device or behavioral study)	Completed	Dec 13, 2017	Dec 22, 2021 (actual)
NCT01726257	Safety and Effectiveness Study of Endovascular Abdominal Aortic Aneurysm Repair Using the Nellix® System	Not phased (device or behavioral study)	Completed	2013-12	2016-06 (actual)
NCT04625660	Detour2 Continued Access Study	Not phased (device or behavioral study)	Completed	Apr 7, 2021	May 14, 2024 (actual)
NCT02407457	Post-Market Study to Assess Outcomes of Patients Treated With AFX System Compared to Other EVAR Devices	Not phased (device or behavioral study)	Completed	2015-03	2018-10 (actual)
NCT01930071	PQ Bypass Guide Wire Delivery System for Femoropopliteal Bypass	Not phased (device or behavioral study)	Completed	2013-11	2015-06 (actual)
NCT01437215	Pilot Study of the Endologix Fenestrated Stent Graft System	Not phased (device or behavioral study)	Completed	Nov 2, 2010	2011-09 (actual)
NCT01070069	Percutaneous Endovascular Aneurysm Repair (PEVAR) Trial	Not phased (device or behavioral study)	Completed	Apr 13, 2010	Mar 9, 2012 (actual)
NCT02949297	Expanding Patient Applicability With Polymer Sealing Ovation Alto Stent Graft Investigational Device Exemption (IDE) Study	Not phased (device or behavioral study)	Completed	Mar 30, 2017	Mar 6, 2019 (actual)
NCT00739401	Suprarenal Proximal Cuff Study for Treatment of Abdominal Aortic Aneurysm	Not phased (device or behavioral study)	Completed	May 5, 2006	2008-08 (actual)
NCT00706394	34mm Cuff Study for Endovascular Repair of Abdominal Aortic Aneurysms	Not phased (device or behavioral study)	Completed	Aug 10, 2007	2013-09 (actual)
NCT01491945	Safety and Effectiveness Trial of the Ventana Fenestrated Stent Graft System	Not phased (device or behavioral study)	Completed	Mar 3, 2013	2017-04 (actual)
NCT01348828	Feasibility and Safety Study of the Endologix Fenestrated Stent Graft System	Not phased (device or behavioral study)	Completed	Oct 19, 2011	2013-05 (actual)
NCT00543270	Powerlink Bifurcated Stent Graft Long-Term Follow-up Study	Not phased (device or behavioral study)	Completed	2005-10	2009-11 (actual)
NCT02048514	The Nellix® EndoVascular Aneurysm Sealing System for the Treatment of Infrarenal Abdominal Aortic Aneurysms	Not phased (device or behavioral study)	Completed	2008-12	2017-12 (actual)