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Viridian Therapeutics, Inc.

HQ: Waltham, MA source · viridiantherapeutics.com ↗ · New England

FDA-approved therapeutic company Clinical Phase 3

2 open jobs · last seen Oct 23, 2026 · 10 sources

Viridian Therapeutics uses antibody discovery and engineering to build a pipeline of investigational therapeutic candidates, including a thyroid eye disease program. From company website Source · checked 2026-10-19

Sources for this description (1)
  • Viridian Therapeutics uses antibody discovery and engineering to build a pipeline of investigational therapeutic candidates, including a thyroid eye disease program.
    • “Leveraging our team’s expertise in antibody discovery and engineering, we have created a robust pipeline of differentiated investigational therapeutic candidates for well-validated targets.” https://www.viridiantherapeutics.com/about/ (2026-10-19)
    • “Our thyroid eye disease program is an example of our drug development strategy in action, aiming to improve upon the standard-of-care and currently available treatment options within commercially established disease areas, with the ultimate goal of improving patients’ lives.” https://www.viridiantherapeutics.com/about/ (2026-10-19)

Disease: thyroid eye disease

Modality: antibody

Keywords: antibody monoclonal antibody VRDN-003 Veligrotug veligrotrug (LUMVOA™)

Location: Waltham, MA · source · Oct 15, 2026

Profile checked Oct 10, 2026

2Open jobs9Trials (company is sponsor)1FDA records (2 yrs)

Hiring

TitleLocation (from posting)Employer postedFirst seen
[TEMPLATE] GeneralWaltham, MA - USSep 24, 2026Oct 16, 2026
[TEMPLATE] General (UK)Remote - UKSep 24, 2026Oct 16, 2026

See all 2 jobs

Timeline

  1. Trial start Phase 4: An Open-Label Trial of Veligrotug in Participants With Thyroid Eye Disease Who Previously Responded to Teprotumumab source ↗
  2. FDA FDA New drug/biologic (novel): LUMVOA (veligrotug-vvze) — BLA761530, Jun 26, 2026. Applicant at approval: Viridian Therapeutics, Inc. source ↗
  3. Trial start Phase 3: A Safety, Tolerability and Pharmacokinetics Study of VRDN-003 in Participants With Thyroid Eye Disease (TED) source ↗
  4. Trial start Phase 3: A Safety and Tolerability Study of VRDN-003 in Participants With Thyroid Eye Disease (TED) source ↗
  5. Trial start Phase 3: An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Chronic Thyroid Eye Disease (TED) source ↗
  6. Trial start Phase 3: An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Active Thyroid Eye Disease (TED) source ↗
  7. Trial start Phase 3: A Randomized, Controlled, Safety and Tolerability Study of VRDN-001 in Participants With Thyroid Eye Disease (TED) source ↗
  8. Trial start Phase 3: An Open-label Study (OLE) for Non-responders of VRDN-001-101 and VRDN-001-301 source ↗
  9. Trial start Phase 3: An Efficacy, Safety, and Tolerability Study of Veligrotug (VRDN-001), in Participants With Chronic Thyroid Eye Disease (TED) source ↗
  10. Trial start Phase 3: A Safety, Tolerability, and Efficacy Study of Veligrotug (VRDN 001) in Participants With Thyroid Eye Disease (TED) source ↗

Upcoming milestones

Estimated primary completion per ClinicalTrials.gov. Dates move.

Clinical trials (lead sponsor) 9

RecordTitlePhaseStatusStartPrimary completion
NCT07832136An Open-Label Trial of Veligrotug in Participants With Thyroid Eye Disease Who Previously Responded to TeprotumumabPhase 4Not yet recruiting2026-092027-04 (estimated)
NCT06625398An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Chronic Thyroid Eye Disease (TED)Phase 3Active, not recruitingAug 27, 2024Mar 4, 2026 (actual)
NCT06625411An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Active Thyroid Eye Disease (TED)Phase 3Active, not recruitingAug 27, 2024Feb 12, 2026 (actual)
NCT06179875An Open-label Study (OLE) for Non-responders of VRDN-001-101 and VRDN-001-301Phase 3CompletedJan 31, 2024Apr 25, 2025 (actual)
NCT06021054An Efficacy, Safety, and Tolerability Study of Veligrotug (VRDN-001), in Participants With Chronic Thyroid Eye Disease (TED)Phase 3CompletedNov 1, 2023Nov 4, 2024 (actual)
NCT05176639A Safety, Tolerability, and Efficacy Study of Veligrotug (VRDN 001) in Participants With Thyroid Eye Disease (TED)Phase 3CompletedNov 16, 2022Jul 15, 2024 (actual)
NCT06384547A Randomized, Controlled, Safety and Tolerability Study of VRDN-001 in Participants With Thyroid Eye Disease (TED)Phase 3CompletedMay 23, 2024May 1, 2025 (actual)
NCT07155668A Safety, Tolerability and Pharmacokinetics Study of VRDN-003 in Participants With Thyroid Eye Disease (TED)Phase 3CompletedJul 1, 2025May 28, 2026 (actual)
NCT06812325A Safety and Tolerability Study of VRDN-003 in Participants With Thyroid Eye Disease (TED)Phase 3Active, not recruitingFeb 3, 2025Apr 22, 2026 (actual)

FDA records (last 2 years)

Open jobs 2

TitleLocation (from posting, not HQ)Employer postedFirst seenLevel
[TEMPLATE] GeneralWaltham, MA - USSep 24, 2026Oct 16, 2026Not stated
[TEMPLATE] General (UK)Remote - UKSep 24, 2026Oct 16, 2026Not stated

Level (Entry/Mid/Senior/Executive) is estimated from the job title and required years of experience. Descriptions are short excerpts (about the first 60 words) of the posting plus skills picked out of it; use Read full posting for the complete text.

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LinkedIn page linked from the company's own site: source · seen 2026-10-12

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