Biotech RadarJobs updated

COMPANY

Theranica

theranica.com ↗

Clinical Phase 3

Keywords: neurology wearable Migraine Acute Treatment of Migraine Fibromyalgia Migraine With Aura Migraine Without Aura Acute Migraine Chronic Migraine Temporomandibular Disorder Orofacial Pain Conditioned Pain Modulation Migraine in Adolescence Menstrual Migraine Migraine Headache Nerivio Nerivio treatment Nerivio Migra neurostimulation Remote Electrical Neuromodulation

Profile checked Oct 10, 2026

27Trials (company is sponsor)

Timeline

  1. Trial start —: Observational Study to Assess Migraine Prediction Tool source ↗
  2. Trial start Not phased (device or behavioral study): The Effect of Remote Electrical Neuromodulation (REN) on Conditioned Pain Modulation (CPM) in Migraine and Fibromyalgia source ↗
  3. Trial start Not phased (device or behavioral study): An Open Label Study Assessing REN Treatment in Headache Management in Temporomandibular Disorders source ↗
  4. Trial start Not phased (device or behavioral study): Migraine Prevention With the Remote Electrical Neuromodulation (REN) Wearable: A Real-world Evidence Study source ↗
  5. Trial start Phase 4: Treatment Patterns Among US Veterans Using Remote Electrical Neuromodulation (REN) for Migraine Treatment source ↗
  6. Trial start Phase 4: Nerivio Efficacy Under High-Frequency Use source ↗
  7. Trial start Phase 4: Nerivio Efficacy by Time of Treatment Onset source ↗
  8. Trial start —: Machine Learning Assessment of Next-Day Migraine Likelihood source ↗
  9. Trial start —: Nerivio Long-term Usage in Patients With Migraine source ↗
  10. Trial start Not phased (device or behavioral study): Treatment of Fibromyalgia With the FibroNova Neuromodulation Device source ↗
  11. Trial start —: A Survey Study to Assess the Accessibility of the Nerivio Device At School source ↗
  12. Trial start —: Acute Treatment of Migraine in Pre-Adolescents: Real-World Analysis of Remote Electrical Neuromodulation (REN) source ↗
  13. Trial start —: A Prospective Post-marketing Observational Study Assessing the Safety and Efficacy of Nerivio for Migraine Prevention. source ↗
  14. Trial start —: Migraine With and Without Aura Characteristics and Response to Remote Electrical Neuromodulation (REN) Treatment source ↗
  15. Trial start —: Real World Data Analysis: Impact of High-Frequency REN Treatments As Migraine Preventive Therapy in Adolescence source ↗
  16. Trial start —: Real-World Evidence (RWE) Data Analysis of 1-year Consecutive Use of Remote Electrical Neuromodulation (REN) source ↗
  17. Trial start —: Safety of Nerivio in Pregnant Women With Migraine source ↗
  18. Trial start —: Real-world Data Analysis of REN Treatment in Migraine Patients source ↗
  19. Trial start Not phased (device or behavioral study): Assessment of Safety and Efficacy of Nerivio for the Migraine Prevention source ↗
  20. Trial start —: Real-world Data Analysis of REN Treatment in Adolescence With Migraine source ↗
  21. Trial start —: Efficacy and Safety of Nerivio for the Acute Treatment of Menstrual Migraine source ↗
  22. Trial start Not phased (device or behavioral study): Efficacy and Safety of Nerivio Device for Acute Treatment of Migraine in People With Chronic Migraine source ↗
  23. Trial start Not phased (device or behavioral study): Safety and Efficacy of Nerivio™ for the Acute Treatment of Migraine in Adolescents source ↗
  24. Trial start Not phased (device or behavioral study): Efficacy and Safety of Nerivio™ for Acute Treatment of Migraine in People With Chronic Migraine source ↗
  25. Trial start Not phased (device or behavioral study): Evaluation of a Novel Device for Treatment of Migraine Headache source ↗

Showing 25 of 27 dated events.

Upcoming milestones

Estimated primary completion per ClinicalTrials.gov. Dates move.

Clinical trials (lead sponsor) 27

RecordTitlePhaseStatusStartPrimary completion
NCT07639944An Open Label Study Assessing REN Treatment in Headache Management in Temporomandibular DisordersNot phased (device or behavioral study)RecruitingMay 4, 2026Jun 1, 2027 (estimated)
NCT07841509The Effect of Remote Electrical Neuromodulation (REN) on Conditioned Pain Modulation (CPM) in Migraine and FibromyalgiaNot phased (device or behavioral study)RecruitingJun 23, 2026Aug 1, 2027 (estimated)
NCT07487701Migraine Prevention With the Remote Electrical Neuromodulation (REN) Wearable: A Real-world Evidence StudyNot phased (device or behavioral study)CompletedFeb 20, 2026Apr 15, 2026 (actual)
NCT07336420Treatment Patterns Among US Veterans Using Remote Electrical Neuromodulation (REN) for Migraine TreatmentPhase 4CompletedJan 9, 2026Jan 25, 2026 (actual)
NCT07336056Nerivio Efficacy Under High-Frequency UsePhase 4Active, not recruitingJan 8, 2026Jan 20, 2026 (estimated)
NCT07227194Machine Learning Assessment of Next-Day Migraine LikelihoodNot listedCompletedFeb 7, 2025Aug 1, 2025 (actual)
NCT05443659Real-world Data Analysis of REN Treatment in Adolescence With MigraineNot listedCompletedJan 1, 2021May 31, 2022 (actual)
NCT05464069Safety of Nerivio in Pregnant Women With MigraineNot listedCompletedAug 1, 2022Nov 28, 2022 (actual)
NCT06138756Acute Treatment of Migraine in Pre-Adolescents: Real-World Analysis of Remote Electrical Neuromodulation (REN)Not listedCompletedOct 1, 2023May 18, 2024 (actual)
NCT06023953Migraine With and Without Aura Characteristics and Response to Remote Electrical Neuromodulation (REN) TreatmentNot listedCompletedJul 1, 2023Sep 30, 2024 (actual)
NCT06976723Nerivio Efficacy by Time of Treatment OnsetPhase 4CompletedMay 7, 2025Jun 10, 2025 (actual)
NCT06738056Nerivio Long-term Usage in Patients With MigraineNot listedCompletedDec 1, 2024Dec 20, 2024 (actual)
NCT03076515Migraine Treatment With Nerivio Migra Neurostimulation DeviceNot phased (device or behavioral study)TerminatedApr 2, 2017Jan 31, 2018 (actual)
NCT04992897Real-world Data Analysis of REN Treatment in Migraine PatientsNot listedCompletedJun 15, 2021Aug 7, 2021 (actual)
NCT05523310Observational Study to Assess Migraine Prediction ToolNot listedSuspendedJan 1, 2030Oct 1, 2030 (estimated)
NCT05760638Real-World Evidence (RWE) Data Analysis of 1-year Consecutive Use of Remote Electrical Neuromodulation (REN)Not listedCompletedMar 1, 2023Mar 26, 2023 (actual)
NCT05769322Real World Data Analysis: Impact of High-Frequency REN Treatments As Migraine Preventive Therapy in AdolescenceNot listedCompletedApr 1, 2023Apr 15, 2023 (actual)
NCT06180577A Survey Study to Assess the Accessibility of the Nerivio Device At SchoolNot listedCompletedFeb 1, 2024May 1, 2024 (actual)
NCT05940870A Prospective Post-marketing Observational Study Assessing the Safety and Efficacy of Nerivio for Migraine Prevention.Not listedCompletedJul 3, 2023Jun 30, 2024 (actual)
NCT06271746Treatment of Fibromyalgia With the FibroNova Neuromodulation DeviceNot phased (device or behavioral study)Unknown status (ClinicalTrials.gov)Mar 4, 2024Mar 1, 2025 (estimated)
NCT04828707Assessment of Safety and Efficacy of Nerivio for the Migraine PreventionNot phased (device or behavioral study)CompletedApr 13, 2021Aug 31, 2022 (actual)
NCT03361423Evaluation of a Novel Device for Treatment of Migraine HeadacheNot phased (device or behavioral study)CompletedDec 17, 2017Nov 25, 2018 (actual)
NCT04089761Safety and Efficacy of Nerivio™ for the Acute Treatment of Migraine in AdolescentsNot phased (device or behavioral study)TerminatedOct 1, 2019May 10, 2020 (actual)
NCT04161807Efficacy and Safety of Nerivio™ for Acute Treatment of Migraine in People With Chronic MigraineNot phased (device or behavioral study)CompletedSep 18, 2019Feb 18, 2020 (actual)
NCT04194008Efficacy and Safety of Nerivio Device for Acute Treatment of Migraine in People With Chronic MigraineNot phased (device or behavioral study)CompletedNov 18, 2019May 22, 2020 (actual)
NCT04600388Efficacy and Safety of Nerivio for the Acute Treatment of Menstrual MigraineNot listedCompletedSep 9, 2020Nov 1, 2020 (actual)
NCT02453399Relief of Migraine Pain Through Electro StimulationNot phased (device or behavioral study)Completed2015-072016-04 (actual)
Feedback