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Celldex Therapeutics

celldex.com ↗ · New England

Clinical Phase 3

46 open jobs · last seen Oct 23, 2026 · 66 sources

Keywords: antibody immunology Chronic Spontaneous Urticaria Non-small Cell Lung Cancer Gastric Cancer Head and Neck Cancer Ovarian Cancer Fallopian Tube Cancer Bladder Urothelial Carcinoma Colorectal Cancer Esophageal Cancer Hepatic Cancer Renal Cell Carcinoma Cholangiocarcinoma Pancreatic Cancer Melanoma Breast Cancer Kidney Neoplasms Bladder Cancer atherosclerosis Chronic Inducible Urticaria Cold Urticaria Symptomatic Dermographism Prurigo Nodularis Primary Peritoneal Carcinoma Mantle Cell Lymphoma Glioblastoma Small Cell Glioblastoma Giant Cell Glioblastoma Gliosarcoma Glioblastoma With Oligodendroglial Component Kidney Diseases Urogenital Neoplasms Urologic Diseases Urologic Neoplasms Neoplasms by Histologic Type Clear-cell Metastatic Renal Cell Carcinoma Cold-Induced Urticaria Atopic Dermatitis Mild to Moderate Asthma

Profile checked Oct 10, 2026

46Open jobs$345.0MRaised (2 yrs)45Trials (company is sponsor)22NIH grants

Hiring

TitleLocation (from posting)Employer postedFirst seen
Senior Director, Regulatory Science and CMC Development StrategyUS-MA-NeedhamNot statedOct 20, 2026
Associate Director, External Drug Product ManufacturingUS-NJ-HamptonNot statedOct 16, 2026
Director, Clinical SuppliesUS-NJ-HamptonNot statedOct 16, 2026
Associate Director, Quality Medical Device EngineerUS-NJ-HamptonNot statedOct 16, 2026
Vice President, Commercial FinanceUS-NJ-HamptonNot statedOct 16, 2026

See all 46 jobs

Timeline

  1. Trial start Phase 1: A Study of CDX-622 in Participants With Mild to Moderate Asthma source ↗
  2. Raise Follow-on offering: $345M (total, as published), announced Apr 6, 2026. Source: company release on GlobeNewswire. source ↗
  3. Trial start Phase 3: A Study to Investigate Efficacy, Safety and Tolerability of Barzolvolimab Versus Placebo in Adults With Cold Induced Urticaria and Symptomatic Dermographism Inadequately Controlled by H1-anti source ↗
  4. Trial start Phase 3: Long-term Efficacy and Safety Extension (LTE) Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria source ↗
  5. Trial start Phase 2: A Study of Barzolvolimab in Patients With Atopic Dermatitis source ↗
  6. Trial start I: A Phase I Study of CDX-622 source ↗
  7. Trial start 3: A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU) source ↗
  8. Trial start 3: A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria source ↗
  9. Trial start Phase 2: A Study of Barzolvolimab in Patients With Prurigo Nodularis source ↗
  10. Trial start Phase 2: A Study of CDX-0159 in Patients With Eosinophilic Esophagitis source ↗
  11. Trial start Phase 1: A Study of CDX-585 in Patients With Advanced Malignancies source ↗
  12. Trial start Phase 2: A Study of CDX-0159 in Patients With Chronic Inducible Urticaria source ↗
  13. Trial start 2: A Phase 2 Study of CDX-0159 in Patients With Chronic Spontaneous Urticaria source ↗
  14. Trial start Phase 1: A Study of CDX-0159 in Patients With Prurigo Nodularis source ↗
  15. Trial start 1: A Phase 1 Study of Subcutaneous CDX-0159 in Healthy Subjects source ↗
  16. Trial start Phase 1: A Single Dose Study of the Safety, Pharmacokinetics and Pharmacodynamics of CDX-0159 in Patients With Cold Contact Urticaria, Symptomatic Dermographism, or Cholinergic Urticaria source ↗
  17. Trial start Phase 1: A Study of CDX-0159 in Patients With Chronic Spontaneous Urticaria source ↗
  18. Trial start Phase 1: A Study of the PD-L1xCD27 Bispecific Antibody CDX-527 in Patients With Advanced Malignancies source ↗
  19. Trial start 1: A Phase 1 Study of CDX-0159 source ↗
  20. Trial start Phase 2: A Study of CDX-3379 and Cetuximab and in Patients With Advanced Head and Neck Squamous Cell Carcinoma source ↗
  21. Trial start Phase 1: A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies source ↗
  22. Trial start Phase 1: A Dose Escalation, Safety and Activity Study of CDX-014 in Patients With Renal Cell Carcinoma and Ovarian Clear Cell Carcinoma source ↗
  23. Trial start Phase 1: A Study to Evaluate the Safety and Pharmacokinetics of CDX-0158 in Adult Patients With Advanced Solid Tumors source ↗
  24. Trial start Phase 1: A Window of Opportunity Study of KTN3379 in Surgically Resectable Head and Neck Cancer Patients source ↗
  25. Trial start Phase 1: A Study of Varlilumab and Atezolizumab in Patients With Advanced Cancer source ↗

Showing 25 of 44 dated events.

Upcoming milestones

Estimated primary completion per ClinicalTrials.gov. Dates move.

Funding

Raised: $345.0M. Last 2 years.

Clinical trials (lead sponsor) 45

RecordTitlePhaseStatusStartPrimary completion
NCT07256392Long-term Efficacy and Safety Extension (LTE) Study of Barzolvolimab in Participants With Chronic Spontaneous UrticariaPhase 3Enrolling by invitationNov 25, 20252028-09 (estimated)
NCT07266402A Study to Investigate Efficacy, Safety and Tolerability of Barzolvolimab Versus Placebo in Adults With Cold Induced Urticaria and Symptomatic Dermographism Inadequately Controlled by H1-antihistamines (EMBARQ - ColdU and SD)Phase 3RecruitingJan 15, 20262028-06 (estimated)
NCT06727552A Study of Barzolvolimab in Patients With Atopic DermatitisPhase 2Active, not recruitingDec 18, 2024May 6, 2026 (actual)
NCT06366750A Study of Barzolvolimab in Patients With Prurigo NodularisPhase 2Active, not recruitingApr 12, 2024Mar 17, 2026 (actual)
NCT07330778A Study of CDX-622 in Participants With Mild to Moderate AsthmaPhase 1RecruitingJun 1, 20262027-03 (estimated)
NCT05774184A Study of CDX-0159 in Patients With Eosinophilic EsophagitisPhase 2CompletedJun 1, 2023Jun 4, 2025 (actual)
NCT06650761A Phase I Study of CDX-622ICompletedNov 1, 2024Apr 24, 2026 (actual)
NCT06445023A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria3Active, not recruitingJul 11, 20242026-10 (estimated)
NCT06455202A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)3Active, not recruitingJul 19, 20242026-10 (estimated)
NCT05405660A Study of CDX-0159 in Patients With Chronic Inducible UrticariaPhase 2CompletedJun 28, 2022Jun 12, 2024 (actual)
NCT05788484A Study of CDX-585 in Patients With Advanced MalignanciesPhase 1CompletedMay 11, 2023May 21, 2025 (actual)
NCT05368285A Phase 2 Study of CDX-0159 in Patients With Chronic Spontaneous Urticaria2CompletedMay 19, 2022Sep 28, 2023 (actual)
NCT03329950A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced MalignanciesPhase 1CompletedDec 1, 2017Sep 13, 2022 (actual)
NCT04944862A Study of CDX-0159 in Patients With Prurigo NodularisPhase 1CompletedNov 8, 2021Jul 31, 2023 (actual)
NCT04538794A Study of CDX-0159 in Patients With Chronic Spontaneous UrticariaPhase 1CompletedSep 24, 2020Jan 17, 2023 (actual)
NCT04440943A Study of the PD-L1xCD27 Bispecific Antibody CDX-527 in Patients With Advanced MalignanciesPhase 1CompletedAug 4, 2020Apr 6, 2023 (actual)
NCT04548869A Single Dose Study of the Safety, Pharmacokinetics and Pharmacodynamics of CDX-0159 in Patients With Cold Contact Urticaria, Symptomatic Dermographism, or Cholinergic UrticariaPhase 1CompletedNov 24, 2020Dec 16, 2022 (actual)
NCT03254927A Study of CDX-3379 and Cetuximab and in Patients With Advanced Head and Neck Squamous Cell CarcinomaPhase 2TerminatedMar 27, 2018Sep 16, 2020 (actual)
NCT05031624A Phase 1 Study of Subcutaneous CDX-0159 in Healthy Subjects1CompletedAug 30, 2021Jan 14, 2022 (actual)
NCT04146129A Phase 1 Study of CDX-01591CompletedOct 29, 2019Apr 6, 2020 (actual)
NCT02837991A Dose Escalation, Safety and Activity Study of CDX-014 in Patients With Renal Cell Carcinoma and Ovarian Clear Cell CarcinomaPhase 1Terminated2016-06Nov 16, 2018 (actual)
NCT01498328A Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive GlioblastomaPhase 2Completed2011-122015-04 (actual)
NCT01094496A Study of the CDX-1307 Vaccine Regimen in Patients With Newly Diagnosed Muscle-Invasive Bladder Cancer (The "N-ABLE" Study)Phase 2Terminated2010-042011-07 (actual)
NCT02335918A Dose Escalation and Cohort Expansion Study of Anti-CD27 (Varlilumab) and Anti-PD-1 (Nivolumab) in Advanced Refractory Solid TumorsPhase 1/Phase 2Completed2015-01Dec 12, 2018 (actual)
NCT02302339A Study of Glembatumumab Vedotin as Monotherapy or in Combination With Immunotherapies in Patients With Advanced MelanomaPhase 2Terminated2014-11Jun 14, 2018 (actual)
NCT02473731A Window of Opportunity Study of KTN3379 in Surgically Resectable Head and Neck Cancer PatientsPhase 1Completed2015-10Sep 22, 2016 (actual)
NCT02642016A Study to Evaluate the Safety and Pharmacokinetics of CDX-0158 in Adult Patients With Advanced Solid TumorsPhase 1Completed2015-12Jan 30, 2018 (actual)
NCT01997333Study of Glembatumumab Vedotin (CDX-011) in Patients With Metastatic, gpNMB Over-Expressing, Triple Negative Breast CancerPhase 2Completed2013-11Nov 30, 2017 (actual)
NCT02386111A Study of Varlilumab (Anti-CD27) and Sunitinib in Patients With Metastatic Clear Cell Renal Cell CarcinomaPhase 1Terminated2015-052017-08 (actual)
NCT03067935Individual Patient Expanded Access-Glembatumumab VedotinNot listedNo longer availableNot listedNot listed
NCT02543645A Study of Varlilumab and Atezolizumab in Patients With Advanced CancerPhase 1Terminated2015-102017-04 (actual)
NCT01460134A Study of CDX-1127 (Varlilumab) in Patients With Select Solid Tumor Types or Hematologic CancersPhase 1Completed2011-102015-12 (actual)
NCT01480479Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed GlioblastomaIIICompleted2011-112016-11 (actual)
NCT00458601Phase II Study of Rindopepimut (CDX-110) in Patients With Glioblastoma MultiformeIICompleted2007-082010-11 (actual)
NCT03068650Expanded Access (Compassionate Use) Treatment Protocol RindopepimutNot listedNo longer availableNot listedNot listed
NCT02456701Enhancing Radioiodine Incorporation Into BRAF Mutant Thyroid Cancers With the Combination of Vemurafenib and KTN3379Phase 1Completed2015-06Oct 13, 2016 (actual)
NCT02014909A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of KTN3379 in Adult Subjects With Advanced Tumors1Completed2014-01May 25, 2017 (actual)
NCT01156753A Study of CDX-011 (CR011-vcMMAE) in Patients With Advanced GPNMB-expressing Breast CancerPhase 2Completed2010-072012-10 (actual)
NCT01465139A Study to Evaluate CDX-301 (rhuFlt3L) in Healthy VolunteersPhase 1Completed2011-102012-11 (actual)
NCT02200380A Safety and Tolerability Study of CDX-301 With or Without Plerixafor for Stem Cell Mobilization in Matched Related Allogeneic Donor/Recipient Sibling Transplant PairsPhase 2Terminated2014-072016-03 (actual)
NCT02413827A Study of Varlilumab (Anti-CD27) and Ipilimumab and CDX-1401 in Patients With Unresectable Stage III or IV MelanomaPhase 1/Phase 2Terminated2015-04Nov 2, 2016 (actual)
NCT00948961A Study of CDX-1401 in Patients With Malignancies Known to Express NY-ESO-1Phase 1/Phase 2Completed2009-092012-06 (actual)
NCT01791686Clinical Trial of CDX-1135 in Pediatric and Adult Patients With Dense Deposit DiseasePhase 1Terminated2013-012014-03 (actual)
NCT00709462A Study of CDX-1307, in Patients With Incurable Breast, Colorectal, Pancreatic, Ovarian or Bladder Cancer (CDX 1307-01)Phase 1Completed2004-032010-05 (actual)
NCT00648102Phase I Study of CDX-1307, hCG-B Vaccine, for Patients With Incurable, Locally Advanced or Metastatic Breast, Colorectal, Pancreatic, Bladder or Ovarian CancerICompleted2006-012009-05 (actual)

NIH awards 22

Annual award amounts. Total $9.5M.

Open jobs 46

TitleLocation (from posting, not HQ)Employer postedFirst seenLevel
Senior Director, Regulatory Science and CMC Development StrategyUS-MA-NeedhamNot statedOct 20, 2026Not stated
Associate Director, External Drug Product ManufacturingUS-NJ-HamptonNot statedOct 16, 2026Senior
Director, Clinical SuppliesUS-NJ-HamptonNot statedOct 16, 2026Senior
Associate Director, Quality Medical Device EngineerUS-NJ-HamptonNot statedOct 16, 2026Senior
Vice President, Commercial FinanceUS-NJ-HamptonNot statedOct 16, 2026Executive
Manager, Biologics Drug Substance External ManufacturingUS-NJ-HamptonNot statedOct 16, 2026Mid
Senior Manager, Biologics Manufacturing Technical SupportUS-NJ-HamptonNot statedOct 16, 2026Senior
Vice President, Corporate ControllerUS-NJ-HamptonNot statedOct 16, 2026Executive
Senior Director, HCP Marketing - Hampton, NJUS-NJ-HamptonNot statedOct 16, 2026Senior
Computer Validation Engineer IVUS-MA-Fall RiverNot statedOct 16, 2026Senior
Associate Director, Full-Stack Engineer, CommercialUS-NJ-HamptonNot statedOct 16, 2026Senior
Executive Director, Stakeholder Advocacy (Remote)US-NJ-HamptonNot statedOct 16, 2026Executive
Quality Assurance Associate IIUS-MA-Fall RiverNot statedOct 16, 2026Mid
Associate Director, Drug SubstanceUS-NJ-HamptonNot statedOct 16, 2026Senior
Senior Director, US HEOR - Hampton, NJUS-NJ-HamptonNot statedOct 16, 2026Senior
Research AssociateUS-NJ-HamptonNot statedOct 16, 2026Entry
Senior Director, Clinical ScienceUS-NJ-HamptonNot statedOct 16, 2026Senior
Director, Clinical ScienceUS-NJ-HamptonNot statedOct 16, 2026Senior
Vice President, US SalesUS-NJ-HamptonNot statedOct 16, 2026Executive
Executive Director, Managed Markets - National and Key Accounts (Remote)US-NJ-HamptonNot statedOct 16, 2026Executive
Senior Manager, Field Medical Science Liaison, Mid Atlantic (NJ/Phil)US-PA-PhiladelphiaNot statedOct 16, 2026Senior
Senior Manager, Field Medical Science Liaison, Great Lakes (Michigan/Ohio)US-NJ-Hampton | US-MINot statedOct 16, 2026Senior
Senior Manager, Field Medical Science Liaison, Mid-South (Tennessee/Kentucky)US-TN-NashvilleNot statedOct 16, 2026Senior
Senior Manager, Field Medical Science Liaison, North Texas/OklahomaUS-TX-DallasNot statedOct 16, 2026Senior
Senior HR PartnerUS-CT-New HavenNot statedOct 16, 2026Senior
Associate Director, BiostatisticsUS-MA-NeedhamNot statedOct 16, 2026Senior
Director, Scientific Publications - Hampton, NJUS-NJ-HamptonNot statedOct 16, 2026Senior
Sr. Director, Medical Evidence Generation, Immunology - Hampton, NJUS-NJ-HamptonNot statedOct 16, 2026Senior
Materials Handler IUS-MA-Fall RiverNot statedOct 16, 2026Entry
Sr. Director, Epidemiology, Immunology - Hampton, NJUS-NJ-HamptonNot statedOct 16, 2026Senior
Executive Medical Science Liaison _ NorthwestUS-NJ-Hampton | US-WA-SeattleNot statedOct 16, 2026Mid
Director, Scientific Communications - Hampton, NJUS-NJ-HamptonNot statedOct 16, 2026Senior
Senior Medical Science Liaison _ South CentralUS-NJ-Hampton | US-TX-Dallas | US-TX-HoustonNot statedOct 16, 2026Senior
Senior Medical Science Liaison _ Mountain WestUS-NJ-Hampton | US-CO-DenverNot statedOct 16, 2026Senior
Senior Medical Science Liaison _ North CentralUS-NJ-Hampton | US-IL-ChicagoNot statedOct 16, 2026Senior
Executive Medical Science Liaison _ Washington DCUS-NJ-Hampton | US-DC-WashingtonNot statedOct 16, 2026Mid
Senior Medical Science Liaison _ SoutheastUS-NJ-Hampton | US-GA-AtlantaNot statedOct 16, 2026Senior
Senior Medical Science Liaison _ New YorkUS-NJ-Hampton | US-NY-New YorkNot statedOct 16, 2026Senior
Director, Supply Chain Planner - CommercialUS-NJ-HamptonNot statedOct 16, 2026Senior
Vice President, Pharmacovigilance & Risk ManagementUS-NJ-HamptonNot statedOct 16, 2026Executive
Global Clinical Project LeaderUS-CT-New Haven | US-NJ-HamptonNot statedOct 16, 2026Senior
Regional Director, Medical Science Liaison - WestUS-CA-Los Angeles | US-CA-San Francisco | US-WA-SeattleNot statedOct 16, 2026Senior
Senior Director, Commercial Learning and Development and OnboardingUS-NJ-HamptonNot statedOct 16, 2026Senior
Regional Director, Medical Science Liaison - EastUS-PA-Philadelphia | US-MA-Boston | US-FL-Miami | US-NC-Raleigh | US-DC-WashingtonNot statedOct 16, 2026Senior
Executive Director, Medical AffairsUS-NJ-HamptonNot statedOct 16, 2026Executive
Executive Director, Trade & DistributionUS | US-MA-Boston | US-TN-Nashville | US-NC-Raleigh | US-PA-PhiladelphiaNot statedOct 16, 2026Executive

Level (Entry/Mid/Senior/Executive) is estimated from the job title and required years of experience. Descriptions are short excerpts (about the first 60 words) of the posting plus skills picked out of it; use Read full posting for the complete text.

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