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COMPANY

ImmunoGenesis

HQ: Houston, TX source · immunogenesis.com ↗

Clinical Phase 2

Keywords: antibody oncology tumors Non-small Cell Lung Cancer Soft Tissue Sarcoma Pancreatic Adenocarcinoma Pancreatic Cancer Metastatic or Locally Advanced Unresectable Pancreatic Adenocarcinoma Metastatic Melanoma Metastatic Prostate Cancer Metastatic Head and Neck Squamous Cell Carcinoma Metastatic Pancreatic Cancer TH-302 IMGS-001

Location: Houston, TX · source · Oct 15, 2026

Profile checked Oct 10, 2026

8Trials (company is sponsor)

Timeline

  1. Trial start Phase 1/Phase 2: A Study of Evofosfamide in Combination with Zalifrelimab and Balstilimab source ↗
  2. Trial start Phase 1: Study to Evaluate IMGS-001 Treatment in Patients With Relapsed or Refractory Advanced Solid Tumors source ↗
  3. Trial start Phase 2: Study of TH-302 or Placebo in Combination With Pemetrexed in Patients With Non-squamous Non-small Cell Lung Cancer source ↗
  4. Trial start I: Phase I TH-302 Plus Gemcitabine Plus Nab-Paclitaxel in Pancreatic Cancer source ↗
  5. Trial start 2: A Phase 2 Biomarker - Enriched Study of TH-302 in Subjects With Advanced Melanoma source ↗
  6. Trial start Phase 3: Clinical Trial Testing TH-302 in Combination With Gemcitabine in Previously Untreated Subjects With Metastatic or Locally Advanced Unresectable Pancreatic Adenocarcinoma source ↗
  7. Trial start Phase 2: Study of the Safety and Efficacy of TH-302 in Combination With Gemcitabine Compared With Gemcitabine Alone in Previously Untreated Patients With Pancreatic Adenocarcinoma source ↗
  8. Trial start Phase 1/Phase 2: Dose-Escalation Study of TH-302 in Combination With Doxorubicin to Treat Patients With Advanced Soft Tissue Sarcoma source ↗

Upcoming milestones

Estimated primary completion per ClinicalTrials.gov. Dates move.

Clinical trials (lead sponsor) 8

RecordTitlePhaseStatusStartPrimary completion
NCT06014502Study to Evaluate IMGS-001 Treatment in Patients With Relapsed or Refractory Advanced Solid TumorsPhase 1RecruitingSep 7, 20232027-12 (estimated)
NCT02093962Study of TH-302 or Placebo in Combination With Pemetrexed in Patients With Non-squamous Non-small Cell Lung CancerPhase 2Terminated2014-062016-04 (actual)
NCT00742963Dose-Escalation Study of TH-302 in Combination With Doxorubicin to Treat Patients With Advanced Soft Tissue SarcomaPhase 1/Phase 2Completed2008-082013-07 (actual)
NCT01144455Study of the Safety and Efficacy of TH-302 in Combination With Gemcitabine Compared With Gemcitabine Alone in Previously Untreated Patients With Pancreatic AdenocarcinomaPhase 2Completed2010-062013-09 (actual)
NCT02047500Phase I TH-302 Plus Gemcitabine Plus Nab-Paclitaxel in Pancreatic CancerITerminated2014-012015-09 (actual)
NCT01746979Clinical Trial Testing TH-302 in Combination With Gemcitabine in Previously Untreated Subjects With Metastatic or Locally Advanced Unresectable Pancreatic AdenocarcinomaPhase 3Completed2012-122016-02 (actual)
NCT01864538A Phase 2 Biomarker - Enriched Study of TH-302 in Subjects With Advanced Melanoma2Terminated2013-052015-09 (actual)
NCT06782555A Study of Evofosfamide in Combination with Zalifrelimab and BalstilimabPhase 1/Phase 2RecruitingJan 8, 20252027-10 (estimated)
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