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COMPANY

Direct Biologics

HQ: Austin, TX source · directbiologics.com ↗ · Southwest

Clinical Phase 3

3 open jobs · last seen Oct 23, 2026 · 10 sources

Profile checked Oct 10, 2026

Keywords: ARDS Inflammatory Bowel Diseases Covid19 COVID-19 Crohn Disease Perianal Fistula Crohn's Disease Perianal Fistula Due to Crohn's Disease Acute Respiratory Distress Syndrome Ulcerative Colitis Hypoxia Cytokine Storm Postviral Syndrome Dyspnea Human ARDS Solid Organ Transplant Rejection Organ Rejection Transplants Organ Rejection ExoFlo DB-3Q Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicles

3Open jobs12Trials (company is sponsor)

Hiring

TitleLocation (from posting)Employer postedFirst seen
Senior AccountantAustin, Texas, United StatesOct 16, 2026Oct 17, 2026
Director, Data ManagementAustin, Texas, United StatesSep 22, 2026Oct 11, 2026
Scientist, Process Sciences - Analytical DevelopmentPoway, California, United StatesSep 15, 2026Oct 11, 2026

See all 3 jobs

Timeline

  1. Trial start Phase 2: DB-3Q for the Treatment of Medically Refractory Crohn's Disease source ↗
  2. Trial start Phase 2: DB-3Q bmMSC-EVs in Patients With Perianal Fistulizing Crohn's Disease source ↗
  3. Trial start Phase 1/Phase 2: Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicles Infusion Treatment for ARDS source ↗
  4. Trial start Phase 1/Phase 2: ExoFlo™ Infusion for Post-Acute COVID-19 and Chronic Post-COVID-19 Syndrome source ↗
  5. Trial start Phase 1/Phase 2: Study of ExoFlo for the Treatment of Perianal Fistulas source ↗
  6. Trial start Phase 1: Study of ExoFlo for the Treatment of Medically Refractory Crohn's Disease source ↗
  7. Trial start Phase 1: Study of ExoFlo for the Treatment of Medically Refractory Ulcerative Colitis source ↗
  8. Trial start Phase 2: Extracellular Vesicles Infusion Treatment for Mild-to-Moderate COVID-19 source ↗
  9. Trial start Phase 3: Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS) source ↗
  10. Trial start Phase 2: Extracellular Vesicle Infusion Treatment for COVID-19 Associated ARDS source ↗

Upcoming milestones

Estimated primary completion per ClinicalTrials.gov. Dates move.

Clinical trials (lead sponsor) 12

RecordTitlePhaseStatusStartPrimary completion
NCT07625293DB-3Q for the Treatment of Medically Refractory Crohn's DiseasePhase 2RecruitingJun 1, 20262027-06 (estimated)
NCT05836883Study of ExoFlo for the Treatment of Perianal FistulasPhase 1/Phase 2TerminatedAug 28, 2023Dec 1, 2024 (actual)
NCT06918808DB-3Q bmMSC-EVs in Patients With Perianal Fistulizing Crohn's DiseasePhase 2RecruitingMay 19, 2025Jul 30, 2027 (estimated)
NCT05354141Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS)Phase 3RecruitingJul 1, 2022Nov 30, 2027 (estimated)
NCT05130983Study of ExoFlo for the Treatment of Medically Refractory Crohn's DiseasePhase 1TerminatedJan 23, 2023Dec 1, 2024 (actual)
NCT05176366Study of ExoFlo for the Treatment of Medically Refractory Ulcerative ColitisPhase 1TerminatedDec 19, 2022Dec 1, 2024 (actual)
NCT04657458Expanded Access for Use of bmMSC-Derived Extracellular Vesicles in Patients With COVID-19 Associated ARDSNot listedNo longer availableNot listedNot listed
NCT05116761ExoFlo™ Infusion for Post-Acute COVID-19 and Chronic Post-COVID-19 SyndromePhase 1/Phase 2Withdrawn2024-112024-11 (estimated)
NCT05127122Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicles Infusion Treatment for ARDSPhase 1/Phase 2Withdrawn2024-122024-12 (estimated)
NCT05215288Expanded Access for Use of ExoFlo in Abdominal Solid Organ Transplant PatientsNot listedNo longer availableNot listedNot listed
NCT04493242Extracellular Vesicle Infusion Treatment for COVID-19 Associated ARDSPhase 2CompletedSep 24, 2020May 1, 2021 (actual)
NCT05125562Extracellular Vesicles Infusion Treatment for Mild-to-Moderate COVID-19Phase 2WithdrawnDec 7, 2022Mar 7, 2023 (estimated)

Open jobs 3

TitleLocation (from posting, not HQ)Employer postedFirst seenLevel
Senior AccountantAustin, Texas, United StatesOct 16, 2026Oct 17, 2026Not stated
Director, Data ManagementAustin, Texas, United StatesSep 22, 2026Oct 11, 2026Senior
Scientist, Process Sciences - Analytical DevelopmentPoway, California, United StatesSep 15, 2026Oct 11, 2026Senior

Level (Entry/Mid/Senior/Executive) is estimated from the job title and required years of experience. Descriptions are short excerpts (about the first 60 words) of the posting plus skills picked out of it; use Read full posting for the complete text.

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LinkedIn page linked from the company's own site: source · seen 2026-10-18

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