COMPANY
Kura Oncology
FDA-approved therapeutic company Clinical Phase 3
Hiring
| Title | Location (from posting) | Employer posted | First seen |
|---|---|---|---|
| Senior Manager/Associate Director, Scientific Communications & Publications | remote | Oct 21, 2026 | Oct 22, 2026 |
| Oncology Account Manager - Detroit | Field Based | Oct 21, 2026 | Oct 22, 2026 |
| Manager, Biosample Operations | Boston, Mass or Remote | Oct 13, 2026 | Oct 14, 2026 |
| Manager/Sr. Manager, IR & Corporate Communications | San Diego, CA | Oct 9, 2026 | Oct 10, 2026 |
| Senior Director, HR Business Partner | United States | Oct 9, 2026 | Oct 9, 2026 |
Trial and FDA signals
- Drug approval + hiring FDA novel approval for KOMZIFTI (NDA 220305, Nov 13, 2025); since then posted 3 manufacturing/quality or commercial roles. FDA NDA 220305 (Nov 13, 2025)
Evidence (1 event)
- Nov 13, 2025 · FDA NDA 220305
openFDA drugsfda: application_number=NDA220305; sponsor_name='KURA'; submission_type=ORIG; submission_number=1; submission_status=AP; submission_status_date=20251113; submission_class_code=TYPE 1; brand_name=['KOMZIFTI']
- Nov 13, 2025 · FDA NDA 220305
Timeline
- Board tracked Radar started tracking this company’s job board (11 open jobs at last check). source ↗
- FDA FDA New drug/biologic (novel): KOMZIFTI (ziftomenib) — NDA220305, Nov 13, 2025. Applicant at approval: Kura Oncology, Inc. source ↗
- Trial start Phase 3: Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML source ↗
- Trial start Phase 1: A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST) source ↗
- Trial start Phase 1: Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia source ↗
- Trial start Phase 1: KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors source ↗
- Trial start Phase 1: A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML source ↗
- Trial start Phase 1: Tipifarnib and Osimertinib in EGFR-mutated Non-Small Cell Lung Cancer source ↗
- Trial start Phase 1/Phase 2: Combination Trial of Tipifarnib and Alpelisib in Adult Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) source ↗
- Trial start Phase 1: Cardiovascular Safety Study of Tipifarnib in Patients With Advanced Solid Malignancies source ↗
- Trial start Phase 1/Phase 2: First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia source ↗
- Trial start Phase 2: Safety and Efficacy of Tipifarnib in Head and Neck Cancer With HRAS Mutations and Impact of HRAS on Response to Therapy source ↗
- Trial start Phase 1: First-in-Human Study of KO-947 in Non-Hematological Malignancies source ↗
- Trial start Phase 2: Tipifarnib in Subjects With Chronic Myelomonocytic Leukemia, Other MDS/MPN, and Acute Myeloid Leukemia source ↗
- Trial start Phase 2: Tipifarnib in Subjects With Myelodysplastic Syndromes source ↗
- Trial start Phase 2: Investigation of Tipifarnib in Treatment of Subjects With Peripheral T-Cell Lymphoma (PTCL) That Have Not Responded to Standard Therapy source ↗
- Trial start II: Phase II Study of Tipifarnib in Squamous Head and Neck Cancer With HRAS Mutations source ↗
Upcoming milestones
- 2026-12 (ESTIMATED) · Phase 1 · Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia · NCT06001788
- 2027-01 (ESTIMATED) · Phase 1 · KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors · NCT06026410
- 2027-12 (ESTIMATED) · Phase 1 · A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST) · NCT06655246
- Oct 16, 2028 (ESTIMATED) · Phase 1/Phase 2 · First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia · NCT04067336
- 2030-04 (ESTIMATED) · Phase 1 · A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML · NCT05735184
- 2031-11 (ESTIMATED) · Phase 3 · Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML · NCT07007312
Open jobs 11
| Title | Location (from posting, not HQ) | Employer posted | First seen | Level |
|---|---|---|---|---|
| Senior Manager/Associate Director, Scientific Communications & Publications | remote | Oct 21, 2026 | Oct 22, 2026 | Not stated |
| Oncology Account Manager - Detroit | Field Based | Oct 21, 2026 | Oct 22, 2026 | Not stated |
| Manager, Biosample Operations | Boston, Mass or Remote | Oct 13, 2026 | Oct 14, 2026 | Mid |
| Manager/Sr. Manager, IR & Corporate Communications | San Diego, CA | Oct 9, 2026 | Oct 10, 2026 | Mid |
| Senior Director, HR Business Partner | United States | Oct 9, 2026 | Oct 9, 2026 | Senior |
| Director, Clinical Business Operations | Boston, MA | Sep 30, 2026 | Oct 9, 2026 | Senior |
| Clinical Trial Associate | Boston, MA | Sep 30, 2026 | Oct 9, 2026 | Entry |
| Associate Director/Director, Medical & Regulatory Writing | Remote | Sep 30, 2026 | Oct 9, 2026 | Senior |
| Oncology Account Manager - Indianapolis/KY/IL | Field Based | Sep 15, 2026 | Oct 9, 2026 | Mid |
| Assoc Director/Director, IT | remote | Sep 11, 2026 | Oct 9, 2026 | Senior |
| CTL/Senior Clinical Trial Leader | Boston, MA | Aug 21, 2025 | Oct 9, 2026 | Mid |
Clinical trials (lead sponsor) 17
| Record | Title | Phase | Status | Start | Primary completion |
|---|---|---|---|---|---|
| NCT07007312 | Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML | Phase 3 | Recruiting | Sep 26, 2025 | 2031-11 (estimated) |
| NCT04997902 | Combination Trial of Tipifarnib and Alpelisib in Adult Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) | Phase 1/Phase 2 | Completed | Dec 7, 2021 | Aug 29, 2025 (actual) |
| NCT06001788 | Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia | Phase 1 | Recruiting | Feb 22, 2024 | 2026-12 (estimated) |
| NCT05738538 | Expanded Access to Ziftomenib | Not listed | Available | Not listed | Not listed |
| NCT04809233 | Expanded Access to Tipifarnib | Not listed | Available | Not listed | Not listed |
| NCT06026410 | KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors | Phase 1 | Recruiting | Oct 18, 2023 | 2027-01 (estimated) |
| NCT04067336 | First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia | Phase 1/Phase 2 | Active, not recruiting | Sep 12, 2019 | Oct 16, 2028 (estimated) |
| NCT05735184 | A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML | Phase 1 | Recruiting | Jul 18, 2023 | 2030-04 (estimated) |
| NCT06655246 | A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST) | Phase 1 | Recruiting | Mar 27, 2025 | 2027-12 (estimated) |
| NCT02779777 | Tipifarnib in Subjects With Myelodysplastic Syndromes | Phase 2 | Terminated | Jun 1, 2016 | Aug 28, 2018 (actual) |
| NCT02807272 | Tipifarnib in Subjects With Chronic Myelomonocytic Leukemia, Other MDS/MPN, and Acute Myeloid Leukemia | Phase 2 | Completed | Jan 10, 2017 | Nov 30, 2020 (actual) |
| NCT02383927 | Phase II Study of Tipifarnib in Squamous Head and Neck Cancer With HRAS Mutations | II | Completed | May 13, 2015 | Dec 14, 2020 (actual) |
| NCT02464228 | Investigation of Tipifarnib in Treatment of Subjects With Peripheral T-Cell Lymphoma (PTCL) That Have Not Responded to Standard Therapy | Phase 2 | Completed | Feb 25, 2016 | Mar 31, 2021 (actual) |
| NCT03719690 | Safety and Efficacy of Tipifarnib in Head and Neck Cancer With HRAS Mutations and Impact of HRAS on Response to Therapy | Phase 2 | Completed | Mar 15, 2019 | May 2, 2023 (actual) |
| NCT04865159 | Cardiovascular Safety Study of Tipifarnib in Patients With Advanced Solid Malignancies | Phase 1 | Terminated | May 6, 2021 | May 2, 2023 (actual) |
| NCT05693090 | Tipifarnib and Osimertinib in EGFR-mutated Non-Small Cell Lung Cancer | Phase 1 | Withdrawn | Feb 1, 2023 | Jul 27, 2027 (estimated) |
| NCT03051035 | First-in-Human Study of KO-947 in Non-Hematological Malignancies | Phase 1 | Terminated | Apr 6, 2017 | Jun 2, 2020 (actual) |
FDA records (last 2 years)
- FDA New drug/biologic (novel): KOMZIFTI (ziftomenib) — NDA220305, Nov 13, 2025. Applicant at approval: Kura Oncology, Inc. source ↗
Raises and investors new
- InvestorListed in the portfolio of ARCH Venture Partners (captured Oct 12, 2026). portfolio page ↗
Connect
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