COMPANY

MiMedx

FDA-cleared device company Clinical Phase 2

Location: Marietta, GA · source · Oct 14, 2026

Profile checked Oct 10, 2026

Keywords: Diabetic Foot Ulcer Knee Osteoarthritis Plantar Fasciitis Scarring Venous Leg Ulcer Pressure Ulcer Diabetic Foot Foot Ulcer Due to Type 2 Diabetes Mellitus Foot Ulcer Treatment of Partial Thickness Burns Partial Nephrectomy Kidney Cancer Renal Function Aggravated Larynx Cancer Pharynx Cancer Pharyngocutaneous Fistula External Hemorrhoid External Hemorrhoid Thrombosed Shoulder Injury Shoulder Sprain Supraspinatus Tear Erectile Dysfunction Leg Ulcer Spinal Stenosis Herniated Disc Osteoarthritis of the Knee Lateral Humeral Epicondylitis Pudendal Nerve Adhesions of Soft Tissue Micronized dHACM EpiCord Dehydrated human amnion/chorion membrane

35Trials (company is sponsor)

Timeline

Aug 27, 2024 Trial start Not phased (device or behavioral study): Modified Platform Trial Evaluating PpLHACM and SOC Versus SOC Alone in the Treatment of Nonhealing DFUs source ↗
Aug 4, 2023 Trial start Not phased (device or behavioral study): Post-Marketing Surveillance of Dehydrated Human Amnion/Chorion Membrane (DHACM) in Non-Ischemic Chronic Wounds source ↗
Mar 24, 2023 Trial start 2B: Phase 2B Micronized DHACM vs. Saline in the Treatment of Knee Osteoarthritis source ↗
Mar 27, 2018 Trial start Phase 2: Micronized dHACM vs. Saline in the Treatment of Osteoarthritis of the Knee source ↗
Mar 19, 2018 Trial start —: Use of Human Dehydrated Amnion Chorion Allograft in Laryngectomy/Pharyngectomy source ↗
Feb 5, 2018 Trial start Not phased (device or behavioral study): Use of Human Dehydrated Amnion Chorion Allograft in Closed Hemorroidectomy source ↗
Jan 9, 2018 Trial start Phase 3: Micronized dHACM Injectable for the Treatment of Achille Tendonitis source ↗
Jan 8, 2018 Trial start Phase 3: Micronized dHACM Injectable for the Treatment of Plantar Fasciitis source ↗
Jun 6, 2017 Trial start Not phased (device or behavioral study): A Single Center, Prospective, Case Series of the Treatment of Pressure Ulcers and Decubitus Ulcers. source ↗
May 23, 2017 Trial start Not phased (device or behavioral study): Use of Human Dehydrated Amnion/Chorion (DHACM) Allograft in Partial Nephrectomy source ↗
Feb 1, 2017 Trial start Not phased (device or behavioral study): Use of Human Dehydrated Umbilical Cord Allograft in Supraspinatus Tendon Repair source ↗
Jan 23, 2017 Trial start Not phased (device or behavioral study): Protocol for the Clinical Evaluation of Lyophilized Amniotic Fluid in the Treatment of Knee Osteoarthritis source ↗
2016-07 Trial start Not phased (device or behavioral study): Dehydrated Human Umbilical Cord Allograft in the Management of Diabetic Foot Ulcers source ↗
2016-05 Trial start Not phased (device or behavioral study): Case Series of Weekly Applications of dHACM in Treatment of Pressure Ulcers source ↗
2016-04 Trial start Not phased (device or behavioral study): Dehydrated Human Amnion Chorion Membrane (dHACM) vs. Control in the Treatment of Partial Thickness Burns. source ↗
2016-04 Trial start Not phased (device or behavioral study): Evaluation of Amniotic Fluid Product in Knee Osteoarthritis source ↗
Oct 1, 2015 Trial start Not phased (device or behavioral study): DHACM in Robotic Assisted Laparoscopic Prostatectomy (RALP) source ↗
2015-06 Trial start Not phased (device or behavioral study): dHACM In the Treatment of Diabetic Foot Ulcers source ↗
2015-05 Trial start Not phased (device or behavioral study): dHACM Mesh In the Treatment of Diabetic Foot Ulcers source ↗
Mar 31, 2015 Trial start Phase 2/Phase 3: Micronized dHACM Injectable for the Treatment of Plantar Fasciitis source ↗
2014-11 Trial start Not phased (device or behavioral study): dHACM in Lumbar Decompression and Microdiscectomy Surgery source ↗
2014-04 Trial start Not phased (device or behavioral study): Amniotic Membrane in Decompressive Craniectomy to Reduce Scarring source ↗
2014-03 Trial start Not phased (device or behavioral study): Use of dHACM in the Treatment of Venous Leg Ulcers source ↗
2014-01 Trial start Not phased (device or behavioral study): Amniotic Membrane in Total Knee Replacements to Reduce Scarring source ↗
2013-09 Trial start Not phased (device or behavioral study): Dehydrated Human Amnion/Chorion Membrane Micrografts(dHACM) Injectable in the Treatment of Recalcitrant Plantar Fasciitis source ↗

Showing 25 of 35 dated events.

Upcoming milestones

2027-01 (ESTIMATED) · Not phased · Post-Marketing Surveillance of Dehydrated Human Amnion/Chorion Membrane (DHACM) in Non-Ischemic Chronic Wounds · NCT06236750

Estimated primary completion per ClinicalTrials.gov. Dates move.

Clinical trials (lead sponsor) 35

Record	Title	Phase	Status	Start	Primary completion
NCT06600724	Modified Platform Trial Evaluating PpLHACM and SOC Versus SOC Alone in the Treatment of Nonhealing DFUs	Not phased (device or behavioral study)	Unknown status (ClinicalTrials.gov)	Aug 27, 2024	2026-08 (estimated)
NCT06236750	Post-Marketing Surveillance of Dehydrated Human Amnion/Chorion Membrane (DHACM) in Non-Ischemic Chronic Wounds	Not phased (device or behavioral study)	Recruiting	Aug 4, 2023	2027-01 (estimated)
NCT05796765	Phase 2B Micronized DHACM vs. Saline in the Treatment of Knee Osteoarthritis	2B	Terminated	Mar 24, 2023	Dec 15, 2023 (actual)
NCT03485157	Micronized dHACM vs. Saline in the Treatment of Osteoarthritis of the Knee	Phase 2	Completed	Mar 27, 2018	Apr 19, 2022 (actual)
NCT03414255	Micronized dHACM Injectable for the Treatment of Achille Tendonitis	Phase 3	Completed	Jan 9, 2018	Mar 30, 2021 (actual)
NCT03414268	Micronized dHACM Injectable for the Treatment of Plantar Fasciitis	Phase 3	Completed	Jan 8, 2018	Mar 17, 2021 (actual)
NCT02765737	Dehydrated Human Amnion Chorion Membrane (dHACM) vs. Control in the Treatment of Partial Thickness Burns.	Not phased (device or behavioral study)	Terminated	2016-04	2019-01 (actual)
NCT02844660	Dehydrated Human Umbilical Cord Allograft in the Management of Diabetic Foot Ulcers	Not phased (device or behavioral study)	Completed	2016-07	2018-07 (actual)
NCT02427191	Micronized dHACM Injectable for the Treatment of Plantar Fasciitis	Phase 2/Phase 3	Completed	Mar 31, 2015	2018-08 (actual)
NCT03323021	Use of Human Dehydrated Amnion/Chorion (DHACM) Allograft in Partial Nephrectomy	Not phased (device or behavioral study)	Completed	May 23, 2017	Feb 21, 2019 (actual)
NCT03529578	A Single Center, Prospective, Case Series of the Treatment of Pressure Ulcers and Decubitus Ulcers.	Not phased (device or behavioral study)	Completed	Jun 6, 2017	Jun 1, 2019 (actual)
NCT03479463	Use of Human Dehydrated Amnion Chorion Allograft in Laryngectomy/Pharyngectomy	Not listed	Terminated	Mar 19, 2018	Mar 30, 2019 (actual)
NCT03074526	Protocol for the Clinical Evaluation of Lyophilized Amniotic Fluid in the Treatment of Knee Osteoarthritis	Not phased (device or behavioral study)	Completed	Jan 23, 2017	Apr 25, 2018 (actual)
NCT01921491	DHACM vs Other Commercially Available Treatments	Not phased (device or behavioral study)	Completed	2013-08	2015-09 (actual)
NCT03479489	Use of Human Dehydrated Amnion Chorion Allograft in Closed Hemorroidectomy	Not phased (device or behavioral study)	Completed	Feb 5, 2018	Dec 30, 2018 (actual)
NCT03084068	Use of Human Dehydrated Umbilical Cord Allograft in Supraspinatus Tendon Repair	Not phased (device or behavioral study)	Completed	Feb 1, 2017	Jan 17, 2019 (actual)
NCT02526173	DHACM in Robotic Assisted Laparoscopic Prostatectomy (RALP)	Not phased (device or behavioral study)	Completed	Oct 1, 2015	Jun 21, 2018 (actual)
NCT01693133	Trial of Dehydrated Human Amnion/Chorion Membrane (dHACM) In the Management of Diabetic Foot Ulcers	Not phased (device or behavioral study)	Completed	2012-07	2018-06 (actual)
NCT02861560	Case Series of Weekly Applications of dHACM in Treatment of Pressure Ulcers	Not phased (device or behavioral study)	Completed	2016-05	2018-05 (actual)
NCT02011503	Use of dHACM in the Treatment of Venous Leg Ulcers	Not phased (device or behavioral study)	Completed	2014-03	Aug 5, 2017 (actual)
NCT02300909	dHACM in Lumbar Decompression and Microdiscectomy Surgery	Not phased (device or behavioral study)	Completed	2014-11	2018-06 (actual)
NCT02033824	Amniotic Membrane in Decompressive Craniectomy to Reduce Scarring	Not phased (device or behavioral study)	Completed	2014-04	2018-06 (actual)
NCT02768155	Evaluation of Amniotic Fluid Product in Knee Osteoarthritis	Not phased (device or behavioral study)	Completed	2016-04	2017-04 (actual)
NCT02589210	dHACM Mesh In the Treatment of Diabetic Foot Ulcers	Not phased (device or behavioral study)	Completed	2015-05	2016-01 (actual)
NCT02587104	dHACM In the Treatment of Diabetic Foot Ulcers	Not phased (device or behavioral study)	Completed	2015-06	2016-05 (actual)
NCT01552447	Human Amniotic Membrane Grafting and Standard of Care Versus Standard of Care Alone in the Treatment of Venous Leg Ulcers	Not phased (device or behavioral study)	Completed	2012-03	2014-05 (actual)
NCT01921569	Micronized Dehydrated Human Amniotic Membrane Suspension in the Treatment of Lateral Epicondylitis	Not phased (device or behavioral study)	Terminated	2013-06	2014-03 (actual)
NCT02088567	Amniotic Membrane in Total Knee Replacements to Reduce Scarring	Not phased (device or behavioral study)	Completed	2014-01	2014-10 (actual)
NCT01552499	Comparative Study of Amniotic Membrane Wound Graft In the Management of Diabetic Foot Ulcers	Not phased (device or behavioral study)	Completed	2012-03	2012-08 (actual)
NCT01832168	Randomized Clinical Trial Using Amniotic Membrane in Robotic Assisted Laparoscopic Prostatectomy	Not phased (device or behavioral study)	Completed	2013-02	2014-06 (actual)
NCT01357187	An Evaluation of the Effect of the AmnioFix Amniotic Membrane Allograft in Patients Undergoing Posterior Instrumentation Removal	Not phased (device or behavioral study)	Completed	2011-09	2014-05 (actual)
NCT01996111	Dehydrated Human Amnion/Chorion Membrane Micrografts(dHACM) Injectable in the Treatment of Recalcitrant Plantar Fasciitis	Not phased (device or behavioral study)	Terminated	2013-09	2014-03 (actual)
NCT01995604	Dehydrated Human Amnion/Chorion Membrane (dHACM) for Recovery After Fractionated Ablative CO2 Laser Resurfacing of the Face	Not phased (device or behavioral study)	Withdrawn	2013-09	2013-11 (estimated)
NCT01659827	Comparative Study of Amniotic Membrane Injectable in the Treatment of Recalcitrant Plantar Fasciitis	Not phased (device or behavioral study)	Completed	2012-09	2013-03 (actual)
NCT01657474	Comparative Study of Two Application Regimens of Amniotic Membrane Wound Graft In the Management of Diabetic Foot Ulcers	Not phased (device or behavioral study)	Completed	2012-09	2013-10 (actual)