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COMPANY

BioCryst Pharmaceuticals

HQ: Durham, NC source · biocryst.com ↗ · Southeast

FDA-approved therapeutic company Clinical Phase 3

24 open jobs · last seen Oct 23, 2026 · 67 sources

Location: Durham, NC · source · Oct 15, 2026

Profile checked Oct 10, 2026

Keywords: Influenza Hereditary Angioedema HAE Paroxysmal Nocturnal Hemoglobinuria COVID-19 Gout Lymphoma Prophylaxis Seasonal Influenza Cough Sore Throat Nasal Congestion Headache Hyperuricemia Arthritis Joint Disease hepatitis c Netherton Syndrome Diabetic Macular Edema Pediatric PNH HAE Hereditary Angioedema Complement 3 Glomerulopathy Immunoglobulin A Nephropathy Membranous Nephropathy Marburg Virus Disease Yellow Fever Filovirus Infections Ebola Virus Infection Uncomplicated Human Influenza Acute Myalgia Fatigue Fever Renal Insufficiency Leukemia, Lymphocytic, Chronic Chronic Lymphocytic Leukemia Leukemia Cutaneous T-cell Lymphoma

24Open jobs54Trials (company is sponsor)1FDA records (2 yrs)17NIH grants

Hiring

TitleLocation (from posting)Employer postedFirst seen
Senior Search & Evaluation DirectorUS_North Carolina_RemoteOct 20, 2026Oct 21, 2026
Sr. Clinical Data Manager (contract)US_North Carolina_RemoteOct 17, 2026Oct 18, 2026
Regional Business Director10 locations (listed on the posting)Oct 15, 2026Oct 16, 2026
Contracts Manager2 locations (listed on the posting)Oct 15, 2026Oct 16, 2026
Regional Business Director6 locations (listed on the posting)Oct 15, 2026Oct 16, 2026

See all 24 jobs

Trial and FDA signals

Job counts as of Oct 18, 2026. All trial and FDA signals

Timeline

  1. Board tracked Radar started tracking this company’s job board (24 open jobs at last check). source ↗
  2. FDA FDA Original approval: ORLADEYO (berotralstat dihydrochloride) — NDA219776, Dec 11, 2025. Applicant at approval: BioCryst Pharmaceuticals, Inc. source ↗
  3. Trial start Phase 1: A Study of Avoralstat In Participants With Diabetic Macular Edema source ↗
  4. Trial start Phase 1: A Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of BCX17725 source ↗
  5. Trial start Phase 1: Dose Escalation of BCX10013 in Participants with Paroxysmal Nocturnal Hemoglobinuria (PNH) source ↗
  6. Trial start Phase 2: Long-term Safety of BCX9930 in Participants With Paroxysmal Nocturnal Hemoglobinuria source ↗
  7. Trial start Phase 3: Berotralstat Treatment in Children With Hereditary Angioedema source ↗
  8. Trial start Phase 2: Study to Evaluate the Safety, Tolerability of BCX9930 in Participants With Either Complement 3 Glomerulopathy (C3G), Immunoglobulin A Nephropathy (IgAN), or Primary Membranous Nephropathy (PM source ↗
  9. Trial start Phase 2: BCX9930 for the Treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH) in Participants With Inadequate Response to C5 Inhibitor Therapy source ↗
  10. Trial start Phase 2: BCX9930 for the Treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH) in Participants Not Receiving Other Complement Inhibitor Therapy source ↗
  11. Trial start Phase 3: Open-label Berotralstat Access to HAE Patients Previously Enrolled in Berotralstat Studies source ↗
  12. Trial start Phase 2: A Long-Term Safety Study of BCX9930 in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) source ↗
  13. Trial start Phase 1: A Study to Evaluate the Safety, Pharmacokinetics and Antiviral Effects of Galidesivir in Yellow Fever or COVID-19 source ↗
  14. Trial start Phase 1/Phase 2: First-in-Human Study of BCX9930 in Healthy Volunteers and Patients With PNH source ↗
  15. Trial start Phase 3: Study to Evaluate the Efficacy and Safety of BCX7353 as an Oral Treatment for the Prevention of HAE Attacks in Japan source ↗
  16. Trial start Phase 1: A Study to Evaluate the Single Dose Safety, Tolerability and Pharmacokinetics of IV BCX4430 source ↗
  17. Trial start Phase 2/Phase 3: A Long Term Safety Study of BCX7353 in Hereditary Angioedema source ↗
  18. Trial start Phase 3: Efficacy and Safety Study of BCX7353 as an Oral Treatment for the Prevention of Attacks in HAE source ↗
  19. Trial start Phase 2: Study of BCX7353 as a Treatment for Attacks of Hereditary Angioedema source ↗
  20. Trial start Phase 1: A Relative Bioavailability Study of Two Formulations of BCX7353 source ↗
  21. Trial start Phase 1: A Drug-Drug Interaction Study to Evaluate Drug Transporter Interactions source ↗
  22. Trial start Phase 2: Efficacy and Safety of BCX7353 to Prevent Angioedema Attacks in Subjects With Hereditary Angioedema source ↗
  23. Trial start Phase 1: An Open-label Drug-Drug Interaction Study to Evaluate the Effect of BCX7353 on Cytochrome P450 Enzyme Activity Using Probe Substrates source ↗
  24. Trial start Phase 3: Safety, PK and Effectiveness of IV Peramivir in Elderly and Higher Risk Subjects With Uncomplicated Influenza source ↗
  25. Trial start Phase 3: Open-label, Long-term Safety Study of Avoralstat in Subjects With Hereditary Angioedema source ↗

Showing 25 of 50 dated events.

Upcoming milestones

Estimated primary completion per ClinicalTrials.gov. Dates move.

Open jobs 24

TitleLocation (from posting, not HQ)Employer postedFirst seenLevel
Senior Search & Evaluation DirectorUS_North Carolina_RemoteOct 20, 2026Oct 21, 2026Not stated
Sr. Clinical Data Manager (contract)US_North Carolina_RemoteOct 17, 2026Oct 18, 2026Not stated
Regional Business Director10 locations (listed on the posting)Oct 15, 2026Oct 16, 2026Not stated
Contracts Manager2 locations (listed on the posting)Oct 15, 2026Oct 16, 2026Not stated
Regional Business Director6 locations (listed on the posting)Oct 15, 2026Oct 16, 2026Not stated
Sr. Clinical Data ManagerUS_North Carolina_RemoteOct 15, 2026Oct 16, 2026Not stated
Product Safety Associate - Postmarketing (Contract)US_North Carolina_RemoteOct 15, 2026Oct 16, 2026Not stated
Rare Disease Specialist (営業担当) - 日本APAC_JapanOct 13, 2026Oct 5, 2026Mid
Bilingual Patient Support Manager - Philadelphia/New Jersey3 locations (listed on the posting)Oct 5, 2026Oct 5, 2026Mid
Exec. Director, Biostatistics2 locations (listed on the posting)Oct 2, 2026Oct 5, 2026Executive
Corporate Communications Content Manager3 locations (listed on the posting)Oct 2, 2026Oct 5, 2026Mid
VP, Drug Substance2 locations (listed on the posting)Oct 1, 2026Oct 5, 2026Executive
Assoc. Director, IT Business Partner - Pharmaceutical Development3 locations (listed on the posting)Oct 1, 2026Oct 5, 2026Senior
Assoc. Director, Regulatory Affairs StrategyUS_North Carolina_RemoteSep 28, 2026Oct 5, 2026Senior
VP, Biostatistics2 locations (listed on the posting)Sep 28, 2026Oct 5, 2026Executive
Exec. Director, Statistical ProgrammingUS_North Carolina_RemoteSep 25, 2026Oct 5, 2026Executive
Assoc. Director, Analytical DevelopmentUS_North Carolina_RemoteSep 23, 2026Oct 5, 2026Senior
Director, Clinical Development SciencesUS_North Carolina_RemoteSep 23, 2026Oct 5, 2026Senior
Sales - Rare Disease Specialist (Los Angeles)2 locations (listed on the posting)Sep 23, 2026Oct 5, 2026Mid
VP, Global Clinical DevelopmentUS_North Carolina_RemoteSep 23, 2026Oct 5, 2026Executive
Sales - Rare Disease Specialist (Hudson Valley, NY)3 locations (listed on the posting)Sep 23, 2026Oct 5, 2026Mid
Exec. Director, US Market Access2 locations (listed on the posting)Sep 23, 2026Oct 5, 2026Executive
Sr. Systems Engineer (Onsite Support)2 locations (listed on the posting)Sep 23, 2026Oct 5, 2026Senior
Director, Drug Product DevelopmentUS_North Carolina_RemoteSep 23, 2026Oct 5, 2026Senior

Level (Entry/Mid/Senior/Executive) is estimated from the job title and required years of experience. Descriptions are short excerpts (about the first 60 words) of the posting plus skills picked out of it; use Read full posting for the complete text.

Clinical trials (lead sponsor) Showing 50 of 54

RecordTitlePhaseStatusStartPrimary completion
NCT06539507A Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of BCX17725Phase 1RecruitingSep 26, 20242026-10 (estimated)
NCT01224795A Study to Evaluate the Efficacy and Safety of Intravenous Peramivir in Subjects With Uncomplicated Influenza.Phase 3Withdrawn2010-102010-11 (actual)
NCT00486980Intramuscular Peramivir for the Treatment of Uncomplicated InfluenzaPhase 3WithdrawnNot listedNot listed
NCT07228559A Study of Avoralstat In Participants With Diabetic Macular EdemaPhase 1TerminatedOct 2, 2025Apr 17, 2026 (actual)
NCT05453968Berotralstat Treatment in Children With Hereditary AngioedemaPhase 3Active, not recruitingOct 25, 2022Sep 11, 2024 (actual)
NCT04933721Open-label Berotralstat Access to HAE Patients Previously Enrolled in Berotralstat StudiesPhase 3Enrolling by invitationJul 23, 20212031-08 (estimated)
NCT0230362612-Week Safety and Efficacy Study of BCX4161 as an Oral Prophylaxis Against HAE AttacksPhase 2/Phase 3CompletedDec 17, 20142016-01 (actual)
NCT05741346Long-term Safety of BCX9930 in Participants With Paroxysmal Nocturnal HemoglobinuriaPhase 2TerminatedJan 18, 2023Jan 31, 2025 (actual)
NCT04702568A Long-Term Safety Study of BCX9930 in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)Phase 2TerminatedDec 18, 2020Oct 4, 2023 (actual)
NCT05116774BCX9930 for the Treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH) in Participants With Inadequate Response to C5 Inhibitor TherapyPhase 2TerminatedDec 6, 2021Sep 14, 2023 (actual)
NCT06100900Dose Escalation of BCX10013 in Participants with Paroxysmal Nocturnal Hemoglobinuria (PNH)Phase 1CompletedOct 24, 2023Dec 11, 2024 (actual)
NCT05116787BCX9930 for the Treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH) in Participants Not Receiving Other Complement Inhibitor TherapyPhase 2TerminatedOct 26, 2021Sep 18, 2023 (actual)
NCT03873116Study to Evaluate the Efficacy and Safety of BCX7353 as an Oral Treatment for the Prevention of HAE Attacks in JapanPhase 3CompletedDec 27, 2018Jul 8, 2021 (actual)
NCT05162066Study to Evaluate the Safety, Tolerability of BCX9930 in Participants With Either Complement 3 Glomerulopathy (C3G), Immunoglobulin A Nephropathy (IgAN), or Primary Membranous Nephropathy (PMN)Phase 2TerminatedFeb 18, 2022Sep 23, 2022 (actual)
NCT03485911Efficacy and Safety Study of BCX7353 as an Oral Treatment for the Prevention of Attacks in HAEPhase 3CompletedFeb 6, 2018Apr 10, 2019 (actual)
NCT03472040A Long Term Safety Study of BCX7353 in Hereditary AngioedemaPhase 2/Phase 3CompletedFeb 16, 2018Apr 27, 2022 (actual)
NCT04330534First-in-Human Study of BCX9930 in Healthy Volunteers and Patients With PNHPhase 1/Phase 2CompletedMar 3, 2020Nov 11, 2020 (actual)
NCT03800173A Study to Evaluate the Single Dose Safety, Tolerability and Pharmacokinetics of IV BCX4430Phase 1CompletedDec 10, 2018Apr 30, 2019 (actual)
NCT03891420A Study to Evaluate the Safety, Pharmacokinetics and Antiviral Effects of Galidesivir in Yellow Fever or COVID-19Phase 1TerminatedApr 9, 2020Jan 31, 2021 (actual)
NCT03240133Study of BCX7353 as a Treatment for Attacks of Hereditary AngioedemaPhase 2CompletedJul 31, 2017Jan 29, 2019 (actual)
NCT02635724Safety, PK and Effectiveness of IV Peramivir in Elderly and Higher Risk Subjects With Uncomplicated InfluenzaPhase 3Completed2015-122018-04 (actual)
NCT02870972Efficacy and Safety of BCX7353 to Prevent Angioedema Attacks in Subjects With Hereditary AngioedemaPhase 2Completed2016-082017-08 (actual)
NCT02369159Safety, PK and Effectiveness of IV Peramivir Versus Oseltamivir in Pediatric Subjects With Uncomplicated InfluenzaPhase 3CompletedMar 11, 2015Oct 28, 2019 (actual)
NCT00610935Intramuscular Peramivir in Subjects With Uncomplicated Acute InfluenzaPhase 3Terminated2008-012008-02 (actual)
NCT04428632Oral Berotralstat Expanded Access ProgramNot listedApproved for marketingNot listedNot listed
NCT03202784A Relative Bioavailability Study of Two Formulations of BCX7353Phase 1CompletedFeb 27, 2017Aug 1, 2017 (actual)
NCT03136237A Drug-Drug Interaction Study to Evaluate Drug Transporter InteractionsPhase 1CompletedFeb 17, 2017Aug 15, 2017 (actual)
NCT02819102An Open-label Drug-Drug Interaction Study to Evaluate the Effect of BCX7353 on Cytochrome P450 Enzyme Activity Using Probe SubstratesPhase 1Completed2016-032016-06 (actual)
NCT02319772A Phase 1 Study to Evaluate the Safety, Tolerability and Pharmacokinetics of BCX44301Completed2014-122016-03 (actual)
NCT02670720Open-label, Long-term Safety Study of Avoralstat in Subjects With Hereditary AngioedemaPhase 3Terminated2015-122016-02 (actual)
NCT02448264First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BCX7353 in Healthy Western and Japanese VolunteersPhase 1Completed2015-052015-11 (actual)
NCT00705406A Phase II, Multicenter, Randomized, Placebo -Controlled, Study To Evaluate The Efficacy and Safety Of Intramuscular Peramivir 600 mg In Subjects With Uncomplicated Acute InfluenzaIICompleted2008-072009-04 (actual)
NCT00453999Evaluation of Efficacy and Safety of Peramivir in Adults With Acute Serious or Potentially Life-threatening InfluenzaPhase 2Completed2007-072008-09 (actual)
NCT00957996Safety Study of IV Peramivir in Hospitalized Subjects With Confirmed or Suspected InfluenzaPhase 3Completed2009-102010-10 (actual)
NCT00958776A Study to Evaluate the Efficacy and Safety of IV Peramivir in Addition to Standard of Care Compared to Standard of Care Alone in Adults and Adolescents Who Are Hospitalized Due to InfluenzaPhase 3Terminated2009-112012-11 (actual)
NCT00419263Evaluation of the Efficacy and Safety of Peramivir in Subjects With Uncomplicated Acute Influenza.Phase 2Completed2007-012007-09 (actual)
NCT02218294Study to Determine How BCX4161 is Metabolized and Eliminated by the BodyPhase 1Completed2014-082014-09 (actual)
NCT01984788Safety and Efficacy of Oral BCX4161 as a Prophylactic Treatment for HAEPhase 2Completed2013-112014-05 (actual)
NCT02125162A Study of the Relative Bioavailability of a New Formulation of BCX4161 and the Effect of Food on BCX4161Phase 1Completed2014-042014-07 (actual)
NCT01265264Study to Evaluate sUA Lowering Activity, Safety and Efficacy of Oral Ulodesine Added to AllopurinolPhase 2Completed2010-122012-07 (actual)
NCT01407874A Randomized, Double-Blind, Dose-Response Study of the Safety and Uric Acid Effects of Oral Ulodesine Added to Allopurinol in Subjects With Gout and Concomitant Moderate Renal InsufficiencyPhase 2Completed2011-092012-07 (actual)
NCT00098332Forodesine (BCX-1777) in Treating Patients With Refractory Stage IIA, Stage IIB, Stage III, Stage IVA, or Stage IVB Cutaneous T-Cell LymphomaPhase 1Completed2004-112010-12 (actual)
NCT00061880BCX-1777 in Treating Patients With Refractory Cutaneous T-Cell LymphomaPhase 1/Phase 2Completed2003-022005-01 (actual)
NCT00073944BCX-1777 in Treating Patients With Refractory CancerPhase 1Completed2003-042005-01 (actual)
NCT00289549Study of Forodesine Hydrochloride in Patients With Advanced, Fludarabine-refractory Chronic Lymphocytic Leukemia (CLL)Phase 2Completed2005-062009-01 (actual)
NCT00985127Study to Evaluate the Urate-Lowering Activity and Safety of Oral BCX4208 Administered in Subjects With GoutPhase 2Completed2009-092010-09 (actual)
NCT00640523Phase II Study of Forodesine in Subjects With Chronic Lymphocytic Leukemia (CLL)IICompleted2008-032010-11 (actual)
NCT01129648Study to Evaluate sUA-Lowering Activity, Safety & PK Interaction of Oral BCX4208 & Allopurinol Admin. in Subjects w/GoutPhase 2Completed2010-052010-11 (actual)
NCT00419081Study of Forodesine Hydrochloride in Patients With Relapsed/Refractory Precursor T-Lymphoblastic Leukemia/Lymphoma Who Have Failed Two or More Prior Treatment RegimensPhase 2Terminated2006-072007-03 (actual)
NCT00501735Forodesine in the Treatment of Cutaneous T-Cell LymphomaPhase 2Completed2007-072010-07 (actual)

FDA records (last 2 years)

NIH awards 17

Annual award amounts. Total $49.0M.

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LinkedIn page linked from the company's own site: source · seen 2026-10-12

Careers page (Oct 8, 2026)

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