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COMPANY

Adagio Medical

HQ: Laguna Hills, CA source · adagiomedical.com ↗ · West Coast

Keywords: cardiovascular Atrial Fibrillation Atrial Flutter Monomorphic Ventricular Tachycardia Persistent Atrial Fibrillation Sustained Ventricular Tachycardia Sustained VT Paroxysmal Atrial Fibrillation Ventricular Tachycardia Ultra Low Temperature Ablation Adagio AF Cryoablation System (iCLAS™) Atrial ablation for subject scheduled for a de novo endocardial ablation of symptomatic, drug-refractory PsAF. VT Cryoablation System Ablation in the ventricles with the Adagio Medical VT Cryoablation System Cryoablation System PolarStart System

Location: Laguna Hills, CA · source · Oct 14, 2026

Profile checked Oct 10, 2026

$19.0MRaised (2 yrs)9Trials (company is sponsor)

Timeline

  1. Trial start Not phased (device or behavioral study): VT Cryoablation System Post-Market Clinical Follow-up (PMCF) Study source ↗
  2. Trial start Not phased (device or behavioral study): Cryoablation for Monomorphic Ventricular Tachycardia (VTS) source ↗
  3. Raise Private placement: $19M (total, as published), announced Oct 20, 2025. Source: SEC filing. source ↗ · Form D filed Oct 29, 2025 SEC Form D ↗
  4. Trial start Not phased (device or behavioral study): Cryoablation for Monomorphic Ventricular Tachycardia source ↗
  5. Trial start Not phased (device or behavioral study): Pulsed Field Ablation and Pulsed Field CRyoAbLation in PErsistent AtriaL FibrilLation source ↗
  6. Trial start Not phased (device or behavioral study): iCLAS™ Cryoablation System Post-Market Clinical Follow-up (PMCF) Study source ↗
  7. Trial start Not phased (device or behavioral study): Cryoablation for Monomorphic Ventricular Tachycardia (CryoCure-VT) source ↗
  8. Trial start Not phased (device or behavioral study): iCLAS™ for Persistent Atrial Fibrillation source ↗
  9. Trial start Not phased (device or behavioral study): Investigation of the Adagio Cryoablation System in Patients With Atrial Fibrillation source ↗
  10. Trial start Not phased (device or behavioral study): Prospective, Multicenter, Investigation of the Adagio Cryoablation System in Subjects With Atrial Flutter source ↗

Upcoming milestones

Estimated primary completion per ClinicalTrials.gov. Dates move.

Funding

Raised: $19.0M. Last 2 years.

Clinical trials (lead sponsor) 9

RecordTitlePhaseStatusStartPrimary completion
NCT07650032Cryoablation for Monomorphic Ventricular Tachycardia (VTS)Not phased (device or behavioral study)RecruitingAug 1, 2026Mar 31, 2027 (estimated)
NCT05675865Cryoablation for Monomorphic Ventricular TachycardiaNot phased (device or behavioral study)Active, not recruitingSep 11, 2023Jan 31, 2027 (estimated)
NCT04061603iCLAS™ for Persistent Atrial FibrillationNot phased (device or behavioral study)CompletedDec 9, 2019Aug 30, 2023 (actual)
NCT05408754Pulsed Field Ablation and Pulsed Field CRyoAbLation in PErsistent AtriaL FibrilLationNot phased (device or behavioral study)CompletedOct 20, 2022Oct 14, 2024 (actual)
NCT05416086iCLAS™ Cryoablation System Post-Market Clinical Follow-up (PMCF) StudyNot phased (device or behavioral study)TerminatedSep 3, 2021Jan 28, 2025 (actual)
NCT06384599VT Cryoablation System Post-Market Clinical Follow-up (PMCF) StudyNot phased (device or behavioral study)Not yet recruitingSep 1, 2026May 1, 2027 (estimated)
NCT04893317Cryoablation for Monomorphic Ventricular Tachycardia (CryoCure-VT)Not phased (device or behavioral study)CompletedMay 26, 2021Jun 30, 2024 (actual)
NCT02839304Investigation of the Adagio Cryoablation System in Patients With Atrial FibrillationNot phased (device or behavioral study)Completed2016-07Mar 31, 2020 (actual)
NCT02355106Prospective, Multicenter, Investigation of the Adagio Cryoablation System in Subjects With Atrial FlutterNot phased (device or behavioral study)Completed2015-01May 1, 2019 (actual)
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