COMPANY
Krystal Biotech
FDA-approved therapeutic company Clinical Phase 3
Hiring
| Title | Location (from posting) | Employer posted | First seen |
|---|---|---|---|
| Patient Access Liaison | Remote | Not stated | Oct 21, 2026 |
| Regional Gene Therapy Liaison - South Midwest (TX/OK/MO/AR/KS) | Remote | Not stated | Oct 21, 2026 |
| Quality Assurance Associate | Moon Township, PA | Not stated | Oct 20, 2026 |
| Quality Assurance Associate | Pittsburgh, PA | Not stated | Oct 17, 2026 |
| Biotech Warehouse / Materials Associate | Moon Township, PA | Not stated | Oct 15, 2026 |
Timeline
- Trial start Early phase 1: A Study to Investigate Safety and Efficacy of KB111 for the Treatment of Hailey-Hailey Disease source ↗
- FDA FDA CBER noteworthy supplement: VYJUVEK (beremagene geperpavec-svdt) — BLA125774/89, Sep 12, 2025. Applicant at approval: Krystal Biotech, Inc. source ↗
- Trial start Phase 1/Phase 2: A Study Comparing KB801 Verse Placebo in Patients With Stage 2 or 3 Neurotrophic Keratitis source ↗
- Trial start Phase 3: A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis Bullosa source ↗
- Trial start Phase 1/Phase 2: A Study Assessing KB304 for the Treatment of Wrinkles in Women source ↗
- Trial start —: A Natural History Study of Corneal Abrasions in Patients With Dystrophic Epidermolysis Bullosa (DEB) source ↗
- Trial start Phase 1/Phase 2: A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs source ↗
- Trial start Phase 1: A Study of KB408 for the Treatment of Alpha-1 Antitrypsin Deficiency source ↗
- Trial start Phase 1/Phase 2: A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors source ↗
- Trial start Phase 1: A Study Assessing KB407 for the Treatment of Cystic Fibrosis source ↗
- Trial start Phase 2: Topical KB105 for the Treatment of TGM1-deficient Autosomal Recessive Congenital Ichthyosis (ARCI) source ↗
- Trial start Phase 1: A Study of Inhaled KB407 for the Treatment of Cystic Fibrosis source ↗
- Trial start Phase 3: A Long-term Treatment With B-VEC for Dystrophic Epidermolysis Bullosa source ↗
- Trial start —: Long-Term Follow-up Protocol source ↗
- Trial start I: A Phase I Study of KB301, a Replication-Incompetent, Non-Integrating Vector Expressing Human Type III Collagen (COL3) for the Treatment of Superficial Skin Depressions source ↗
- Trial start Phase 3: Ph 3 Efficacy and Safety of B-VEC for the Treatment of DEB source ↗
- Trial start —: The Natural History of Wounds in Patients With Dystrophic Epidermolysis Bullosa (DEB) source ↗
- Trial start Phase 1/Phase 2: Topical KB105 Gene Therapy for the Treatment of TGM1-deficient Autosomal Recessive Congenital Ichthyosis (ARCI) source ↗
- Trial start I: A Phase I/II Study of KB103, a Topical HSV1-COL7, on DEB Patients source ↗
Upcoming milestones
- 2026-11 (ESTIMATED) · Early phase 1 · A Study to Investigate Safety and Efficacy of KB111 for the Treatment of Hailey-Hailey Disease · NCT07717346
- 2026-12 (ESTIMATED) · Phase 1 · A Study Assessing KB407 for the Treatment of Cystic Fibrosis · NCT05504837
- 2026-12 (ESTIMATED) · Phase 3 · A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis Bullosa · NCT07016750
- 2026-12 (ESTIMATED) · Phase 1/Phase 2 · A Study Comparing KB801 Verse Placebo in Patients With Stage 2 or 3 Neurotrophic Keratitis · NCT06999733
- 2027-02 (ESTIMATED) · Phase 1/Phase 2 · A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs · NCT06228326
- 2027-07 (ESTIMATED) · Phase 1/Phase 2 · A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors · NCT05970497
- May 25, 2028 (ESTIMATED) · · Long-Term Follow-up Protocol · NCT04917887
Clinical trials (lead sponsor) 18
| Record | Title | Phase | Status | Start | Primary completion |
|---|---|---|---|---|---|
| NCT07717346 | A Study to Investigate Safety and Efficacy of KB111 for the Treatment of Hailey-Hailey Disease | Early phase 1 | Recruiting | May 6, 2026 | 2026-11 (estimated) |
| NCT05504837 | A Study Assessing KB407 for the Treatment of Cystic Fibrosis | Phase 1 | Recruiting | Jun 30, 2023 | 2026-12 (estimated) |
| NCT07016750 | A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis Bullosa | Phase 3 | Recruiting | Jun 20, 2025 | 2026-12 (estimated) |
| NCT06999733 | A Study Comparing KB801 Verse Placebo in Patients With Stage 2 or 3 Neurotrophic Keratitis | Phase 1/Phase 2 | Recruiting | Jul 7, 2025 | 2026-12 (estimated) |
| NCT06228326 | A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs | Phase 1/Phase 2 | Recruiting | Apr 17, 2024 | 2027-02 (estimated) |
| NCT06049082 | A Study of KB408 for the Treatment of Alpha-1 Antitrypsin Deficiency | Phase 1 | Recruiting | Feb 15, 2024 | 2025-12 (estimated) |
| NCT06563414 | A Natural History Study of Corneal Abrasions in Patients With Dystrophic Epidermolysis Bullosa (DEB) | Not listed | Recruiting | Aug 2, 2024 | 2025-12 (estimated) |
| NCT05970497 | A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors | Phase 1/Phase 2 | Recruiting | Oct 31, 2023 | 2027-07 (estimated) |
| NCT06724900 | A Study Assessing KB304 for the Treatment of Wrinkles in Women | Phase 1/Phase 2 | Active, not recruiting | Nov 20, 2024 | 2025-07 (estimated) |
| NCT04540900 | A Phase I Study of KB301, a Replication-Incompetent, Non-Integrating Vector Expressing Human Type III Collagen (COL3) for the Treatment of Superficial Skin Depressions | I | Active, not recruiting | Oct 7, 2020 | Oct 16, 2024 (actual) |
| NCT04917874 | A Long-term Treatment With B-VEC for Dystrophic Epidermolysis Bullosa | Phase 3 | Completed | May 25, 2021 | Jul 31, 2023 (actual) |
| NCT05095246 | A Study of Inhaled KB407 for the Treatment of Cystic Fibrosis | Phase 1 | Withdrawn | Mar 8, 2022 | Jul 1, 2024 (estimated) |
| NCT05735158 | Topical KB105 for the Treatment of TGM1-deficient Autosomal Recessive Congenital Ichthyosis (ARCI) | Phase 2 | Unknown status (ClinicalTrials.gov) | 2023-03 | 2024-03 (estimated) |
| NCT04491604 | Ph 3 Efficacy and Safety of B-VEC for the Treatment of DEB | Phase 3 | Completed | Aug 17, 2020 | Oct 29, 2021 (actual) |
| NCT03536143 | A Phase I/II Study of KB103, a Topical HSV1-COL7, on DEB Patients | I | Completed | May 6, 2018 | Nov 1, 2019 (actual) |
| NCT04214002 | The Natural History of Wounds in Patients With Dystrophic Epidermolysis Bullosa (DEB) | Not listed | Withdrawn | 2020-01 | Feb 24, 2020 (actual) |
| NCT04047732 | Topical KB105 Gene Therapy for the Treatment of TGM1-deficient Autosomal Recessive Congenital Ichthyosis (ARCI) | Phase 1/Phase 2 | Unknown status (ClinicalTrials.gov) | Aug 27, 2019 | 2022-10 (estimated) |
| NCT04917887 | Long-Term Follow-up Protocol | Not listed | Recruiting | May 25, 2021 | May 25, 2028 (estimated) |
FDA records (last 2 years)
- FDA CBER noteworthy supplement: VYJUVEK (beremagene geperpavec-svdt) — BLA125774/89, Sep 12, 2025. Applicant at approval: Krystal Biotech, Inc. source ↗
Open jobs 11
| Title | Location (from posting, not HQ) | Employer posted | First seen | Level |
|---|---|---|---|---|
| Patient Access Liaison | Remote | Not stated | Oct 21, 2026 | Not stated |
| Regional Gene Therapy Liaison - South Midwest (TX/OK/MO/AR/KS) | Remote | Not stated | Oct 21, 2026 | Not stated |
| Quality Assurance Associate | Moon Township, PA | Not stated | Oct 20, 2026 | Not stated |
| Quality Assurance Associate | Pittsburgh, PA | Not stated | Oct 17, 2026 | Not stated |
| Biotech Warehouse / Materials Associate | Moon Township, PA | Not stated | Oct 15, 2026 | Entry |
| Warehouse Associate | Pittsburgh, PA | Not stated | Oct 15, 2026 | Entry |
| Senior Biostatistician | Pittsburgh, PA | Not stated | Oct 11, 2026 | Senior |
| Validation (CSV) Associate | Pittsburgh, PA | Not stated | Oct 11, 2026 | Entry |
| Quality Assurance Document Control Associate | Moon Township, PA | Not stated | Oct 11, 2026 | Entry |
| Quality Assurance Training Coordinator | Pittsburgh, PA | Not stated | Oct 11, 2026 | Entry |
| Regional Gene Therapy Consultant - Pacific Northwest | Remote | Not stated | Oct 11, 2026 | Senior |
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