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Autobahn Therapeutics

HQ: San Diego, CA source · autobahntx.com ↗ · West Coast

Clinical Phase 2

Our lead molecule, elunetirom (ABX-002), is a potent and selective, CNS-directed thyroid receptor (CNS-TR) agonist that we are developing as a potential treatment for multiple CNS disorders, initially focusing on the adjunctive treatment for people with major depressive disorder (MDD) and bipolar disorder depression. From company website Source · Oct 12, 2026

Keywords: ABX-002 Bipolar Disorder Depression MDD

Profile checked Oct 10, 2026

4Trials (company is sponsor)

Raises and deals from press releases

Raises announced in these releases: $100M disclosed.

From the company’s own releases; this list is partial. All raises and deals

Timeline

  1. Trial start Phase 2: Study of ABX-002 for the Adjunctive Treatment of Depressive Episodes Associated With Bipolar Disorder in Adults source ↗
  2. Trial start Phase 1: ABX-002 Bioequivalence and Effect of Food Study in Healthy Adult Participants source ↗
  3. Trial start Phase 2: Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY) source ↗
  4. Raise Series C · $100M source ↗
  5. Trial start Phase 1: SAD/MAD of ABX-002-1902 Investigating the Safety, Pharmacokinetics/Pharmacodynamics of in Healthy Subjects source ↗

Clinical trials (lead sponsor) 4

RecordTitlePhaseStatusStartPrimary completion
NCT07652697ABX-002 Bioequivalence and Effect of Food Study in Healthy Adult ParticipantsPhase 1CompletedJan 2, 2025Feb 17, 2025 (actual)
NCT06869187Study of ABX-002 for the Adjunctive Treatment of Depressive Episodes Associated With Bipolar Disorder in AdultsPhase 2Active, not recruitingMar 28, 2025Apr 22, 2026 (actual)
NCT06633016Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)Phase 2RecruitingSep 20, 20242026-06 (estimated)
NCT05528315SAD/MAD of ABX-002-1902 Investigating the Safety, Pharmacokinetics/Pharmacodynamics of in Healthy SubjectsPhase 1CompletedOct 12, 2022Jun 26, 2023 (actual)

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