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Shattuck Labs

HQ: Austin, TX source · shattucklabs.com ↗ · Southwest

Clinical Phase 2

3 open jobs · last seen Oct 23, 2026 · 9 sources

Keywords: antibody inflammatory bowel disease Fallopian Tube Cancer Ovarian Cancer Primary Peritoneal Carcinoma Crohn's Disease Acute Myeloid Leukemia Myelodysplastic Syndromes Platinum-resistant Ovarian Cancer Epithelial Ovarian Cancer Platinum-Resistant Fallopian Tube Carcinoma Platinum-Resistant Primary Peritoneal Carcinoma Squamous Cell Carcinoma of the Head and Neck Melanoma Non Small Cell Lung Cancer Urothelial Carcinoma Gastric Adenocarcinoma Gastroesophageal Junction Adenocarcinoma Squamous Cell Carcinoma of the Anus Squamous Cell Carcinoma of the Cervix Squamous Cell Carcinoma of the Skin Renal Cell Carcinoma Hodgkin Lymphoma Diffuse Large B Cell Lymphoma Mismatch Repair Deficient or MSI-High Solid Tumors Cutaneous Squamous Cell Carcinoma Squamous Cell Carcinoma of Head and Neck SL-325 SL-172154 SL-279252 Drug: SL-172154

Profile checked Oct 10, 2026

3Open jobs$206.0MRaised (2 yrs)7Trials (company is sponsor)

Hiring

TitleLocation (from posting)Employer postedFirst seen
Clinical Trials AssociateShattuck Labs, Durham, NC, USOct 6, 2026Oct 11, 2026
Associate Director, Analytical Sciences (Tech Ops)Durham, NC, USAug 11, 2026Oct 11, 2026
Scientist (I, II or Senior), Formulation Sciences (Tech Ops)Durham, NC, USAug 11, 2026Oct 11, 2026

See all 3 jobs

Timeline

  1. Trial start Phase 2: A Study of SL-325 in Crohn's Disease Patients source ↗
  2. Trial start 1: Phase 1 Study of SL-325 in Healthy Volunteers source ↗
  3. Raise Private placement: $103M (up to, as announced), announced Aug 26, 2025. Source: company release on GlobeNewswire. source ↗
  4. Raise Private placement: $103M (total, as published), announced Aug 5, 2025. Source: SEC filing. source ↗
  5. Trial start 1: Phase 1b Study of SL-172154 Administered With Combination Agent(s) in Subjects With Ovarian Cancers source ↗
  6. Trial start 1: Phase 1 Study of Shattuck Labs (SL)-172154 in Subjects With MDS or AML source ↗
  7. Trial start Phase 1: Ph1 Study of SL-172154 Administered Intratumorally in Subjects With Squamous Cell Carcinoma of the Head and Neck or Skin source ↗
  8. Trial start 1: Phase 1 Study of SL-172154 (SIRPα-Fc-CD40L) in Subjects With Ovarian Cancer source ↗
  9. Trial start Phase 1: SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas source ↗

Upcoming milestones

Estimated primary completion per ClinicalTrials.gov. Dates move.

Funding

Raised: $206.0M. Last 2 years.

Clinical trials (lead sponsor) 7

RecordTitlePhaseStatusStartPrimary completion
NCT07753850A Study of SL-325 in Crohn's Disease PatientsPhase 2Not yet recruiting2026-102028-07 (estimated)
NCT07158437Phase 1 Study of SL-325 in Healthy Volunteers1Active, not recruitingSep 18, 20252026-07 (estimated)
NCT05275439Phase 1 Study of Shattuck Labs (SL)-172154 in Subjects With MDS or AML1TerminatedMar 17, 2022Feb 6, 2025 (actual)
NCT05483933Phase 1b Study of SL-172154 Administered With Combination Agent(s) in Subjects With Ovarian Cancers1CompletedAug 18, 2022Feb 7, 2025 (actual)
NCT03894618SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or LymphomasPhase 1CompletedMar 26, 2019May 4, 2023 (actual)
NCT04502888Ph1 Study of SL-172154 Administered Intratumorally in Subjects With Squamous Cell Carcinoma of the Head and Neck or SkinPhase 1TerminatedSep 17, 2020Apr 8, 2022 (actual)
NCT04406623Phase 1 Study of SL-172154 (SIRPα-Fc-CD40L) in Subjects With Ovarian Cancer1CompletedJun 29, 2020Feb 2, 2023 (actual)

Raises and investors new

Form D raises come from the company’s own SEC filing (last 2 years).

Open jobs 3

TitleLocation (from posting, not HQ)Employer postedFirst seenLevel
Clinical Trials AssociateShattuck Labs, Durham, NC, USOct 6, 2026Oct 11, 2026Entry
Associate Director, Analytical Sciences (Tech Ops)Durham, NC, USAug 11, 2026Oct 11, 2026Senior
Scientist (I, II or Senior), Formulation Sciences (Tech Ops)Durham, NC, USAug 11, 2026Oct 11, 2026Mid

Level (Entry/Mid/Senior/Executive) is estimated from the job title and required years of experience. Descriptions are short excerpts (about the first 60 words) of the posting plus skills picked out of it; use Read full posting for the complete text.

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LinkedIn page linked from the company's own site: source · seen 2026-10-18

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